FI951633A0 - Förökad produktion av sekretoriska proteiner vid eukaryotiska rekombinantceller - Google Patents

Förökad produktion av sekretoriska proteiner vid eukaryotiska rekombinantceller

Info

Publication number
FI951633A0
FI951633A0 FI951633A FI951633A FI951633A0 FI 951633 A0 FI951633 A0 FI 951633A0 FI 951633 A FI951633 A FI 951633A FI 951633 A FI951633 A FI 951633A FI 951633 A0 FI951633 A0 FI 951633A0
Authority
FI
Finland
Prior art keywords
dna sequence
recombinant cells
increased production
secretory proteins
eukaryotic recombinant
Prior art date
Application number
FI951633A
Other languages
English (en)
Finnish (fi)
Other versions
FI114482B (sv
FI951633A (sv
Inventor
Sirkka Keraenen
Markku Aalto
Mika Outola
Hans Ronne
Merja Penttilae
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Priority to FI951633A priority Critical patent/FI114482B/sv
Publication of FI951633A0 publication Critical patent/FI951633A0/sv
Publication of FI951633A publication Critical patent/FI951633A/sv
Application granted granted Critical
Publication of FI114482B publication Critical patent/FI114482B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Seasonings (AREA)
  • Peptides Or Proteins (AREA)
FI951633A 1992-10-06 1995-04-05 Förökad produktion av sekretoriska proteiner vid eukaryotiska rekombinantceller FI114482B (sv)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI951633A FI114482B (sv) 1992-10-06 1995-04-05 Förökad produktion av sekretoriska proteiner vid eukaryotiska rekombinantceller

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
FI924494A FI924494A0 (fi) 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
FI924494 1992-10-06
FI9300402 1993-10-06
PCT/FI1993/000402 WO1994008024A1 (en) 1992-10-06 1993-10-06 Increased production of secreted proteins by recombinant eukaryotic cells
FI951633 1995-04-05
FI951633A FI114482B (sv) 1992-10-06 1995-04-05 Förökad produktion av sekretoriska proteiner vid eukaryotiska rekombinantceller

Publications (3)

Publication Number Publication Date
FI951633A0 true FI951633A0 (sv) 1995-04-05
FI951633A FI951633A (sv) 1995-04-05
FI114482B FI114482B (sv) 2004-10-29

Family

ID=8535988

Family Applications (2)

Application Number Title Priority Date Filing Date
FI924494A FI924494A0 (fi) 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
FI951633A FI114482B (sv) 1992-10-06 1995-04-05 Förökad produktion av sekretoriska proteiner vid eukaryotiska rekombinantceller

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI924494A FI924494A0 (fi) 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller

Country Status (14)

Country Link
US (1) US5789193A (sv)
EP (1) EP0665890B1 (sv)
JP (1) JP3638599B2 (sv)
AT (1) ATE254663T1 (sv)
AU (1) AU678402B2 (sv)
CA (1) CA2146240C (sv)
DE (1) DE69333304T2 (sv)
DK (1) DK0665890T3 (sv)
EE (1) EE03074B1 (sv)
ES (1) ES2211870T3 (sv)
FI (2) FI924494A0 (sv)
NO (1) NO319132B1 (sv)
NZ (1) NZ256425A (sv)
WO (1) WO1994008024A1 (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922561A (en) * 1994-10-03 1999-07-13 Novo Nordisk Biotech, Inc. Genes encoding signal recognition particle of Aspergillus niger
DE19920712A1 (de) * 1999-05-05 2000-11-09 Rhein Biotech Proz & Prod Gmbh Verfahren zum Herstellen eines rekombinanten Proteines
JP4849408B2 (ja) 2004-03-01 2012-01-11 財団法人北九州産業学術推進機構 タンパク質産生新規ヒト細胞株、新規ヒト細胞株の選択方法、新規ヒト細胞株の使用、それらからのタンパク質産生方法及び精製方法、及び新規ヒト細胞株を利用した薬学組成物
US20090247609A1 (en) * 2007-12-20 2009-10-01 Hitto Kaufmann Sm-protein based secretion engineering
EP3020273B1 (en) * 2014-11-17 2018-07-04 Competence Centre on Health Technologies A method of producing biotechnological drugs using transgenic bovine animals
WO2019209241A1 (en) 2018-04-23 2019-10-31 Dupont Nutrition Biosciences Aps Increasing export of 2' fucosyllactose from microbial cells through the expression of a heterologous nucleic acid
EP4194560A1 (en) 2021-12-08 2023-06-14 European Molecular Biology Laboratory Improved production of secreted proteins in fungal cells
CN114717124B (zh) * 2022-04-19 2024-07-12 天津科技大学 一株高产麦角甾醇的酿酒酵母工程菌株、构建方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK175243B1 (da) * 1987-03-23 2004-07-19 Zymogenetics Inc Ekspressionsvektor, der er i stand til at styre ekspression af heterologe gener eller cDNA i gær, gærværtscelle samt fremgangsmåde til öget produktion af proteiner i gærværtsceller

Also Published As

Publication number Publication date
NO319132B1 (no) 2005-06-20
DE69333304D1 (de) 2003-12-24
CA2146240C (en) 2007-05-01
AU5112793A (en) 1994-04-26
NZ256425A (en) 1996-08-27
NO951315D0 (no) 1995-04-05
AU678402B2 (en) 1997-05-29
CA2146240A1 (en) 1994-04-14
JP3638599B2 (ja) 2005-04-13
ATE254663T1 (de) 2003-12-15
ES2211870T3 (es) 2004-07-16
FI114482B (sv) 2004-10-29
FI951633A (sv) 1995-04-05
US5789193A (en) 1998-08-04
EE03074B1 (et) 1998-02-16
JPH08501695A (ja) 1996-02-27
NO951315L (no) 1995-06-06
DK0665890T3 (da) 2004-03-08
WO1994008024A1 (en) 1994-04-14
EP0665890A1 (en) 1995-08-09
EP0665890B1 (en) 2003-11-19
FI924494A0 (fi) 1992-10-06
DE69333304T2 (de) 2004-08-26

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