DK1129190T3 - Human TSLP DNA og polypeptider - Google Patents

Human TSLP DNA og polypeptider

Info

Publication number
DK1129190T3
DK1129190T3 DK99960372T DK99960372T DK1129190T3 DK 1129190 T3 DK1129190 T3 DK 1129190T3 DK 99960372 T DK99960372 T DK 99960372T DK 99960372 T DK99960372 T DK 99960372T DK 1129190 T3 DK1129190 T3 DK 1129190T3
Authority
DK
Denmark
Prior art keywords
polypeptides
human tslp
tslp dna
dna
purified
Prior art date
Application number
DK99960372T
Other languages
English (en)
Other versions
DK1129190T4 (da
Inventor
Stewart Lyman
Hilary Mckenna
Allison Armstrong
John E Sims
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22322307&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1129190(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of DK1129190T3 publication Critical patent/DK1129190T3/da
Application granted granted Critical
Publication of DK1129190T4 publication Critical patent/DK1129190T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5418—IL-7
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK99960372.3T 1998-11-13 1999-11-12 Human TSLP DNA og polypeptider DK1129190T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10845298P 1998-11-13 1998-11-13
PCT/US1999/027069 WO2000029581A1 (en) 1998-11-13 1999-11-12 Human tslp dna and polypeptides

Publications (2)

Publication Number Publication Date
DK1129190T3 true DK1129190T3 (da) 2007-09-24
DK1129190T4 DK1129190T4 (da) 2017-04-03

Family

ID=22322307

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99960372.3T DK1129190T4 (da) 1998-11-13 1999-11-12 Human TSLP DNA og polypeptider

Country Status (14)

Country Link
US (8) US6555520B2 (da)
EP (1) EP1129190B2 (da)
JP (3) JP4454859B2 (da)
AT (1) ATE362534T2 (da)
AU (1) AU755562B2 (da)
CA (1) CA2349762C (da)
CY (1) CY1106806T1 (da)
DE (1) DE69936105T3 (da)
DK (1) DK1129190T4 (da)
ES (1) ES2288036T5 (da)
IL (3) IL143034A0 (da)
NZ (1) NZ512105A (da)
PT (1) PT1129190E (da)
WO (1) WO2000029581A1 (da)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6246199A (en) * 1998-09-21 2000-04-10 Schering Corporation Human interleukin-b50, therapeutic uses
US20030099947A1 (en) * 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
WO2000029581A1 (en) 1998-11-13 2000-05-25 Immunex Corporation Human tslp dna and polypeptides
US6890734B2 (en) 2000-11-10 2005-05-10 Schering Corporation Nucleic acids encoding a cytokine receptor complex
WO2003032898A2 (en) * 2001-07-23 2003-04-24 Immunex Corporation Modified human thymic stromal lymphopoietin
PT2311869E (pt) * 2002-02-01 2013-03-04 Merck Sharp & Dohme Utilização de reagentes relacionados com citoquinas de mamíferos
WO2005007186A1 (en) * 2003-07-18 2005-01-27 Schering Corporation Treatment and diagnosis of neoplasms using thymic stromal lymphopoietin
US20050249712A1 (en) * 2004-03-23 2005-11-10 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services Methods for use of TSLP and agonists and antagonists thereof
CA2575721A1 (en) * 2004-07-28 2006-03-02 Tanox, Inc. Thymic stromal lymphopoietin promoter and uses therefor
US20060171943A1 (en) * 2005-02-01 2006-08-03 Amgen Inc. Compositions and methods of treating fibrotic disorders
CA2513350A1 (en) * 2005-03-02 2006-09-02 Sydney West Area Health Service Treatment for multiple sclerosis
RU2486202C2 (ru) * 2006-01-13 2013-06-27 Айрм Ллк Антитела к рецептору тимусного стромального лимфопоэтина
GB0603683D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
SE532251C2 (sv) * 2006-11-28 2009-11-24 Theravac Pharmaceuticals Ab Nya formuleringar av TSLP för behandling av TH2-medierade inflammatoriska sjukdomar genom vaccinering
WO2008076255A2 (en) * 2006-12-14 2008-06-26 Schering-Plough Ltd. Canine thymic stromal lymphopoietin protein and uses thereof
AU2007334499B2 (en) 2006-12-14 2014-04-24 Merck Sharp & Dohme Corp. Engineered anti-TSLP antibody
TW201718635A (zh) 2007-03-06 2017-06-01 安美基公司 變異之活動素受體多肽及其用途
US8501678B2 (en) 2007-03-06 2013-08-06 Atara Biotherapeutics, Inc. Variant activin receptor polypeptides and uses thereof
US7982016B2 (en) 2007-09-10 2011-07-19 Amgen Inc. Antigen binding proteins capable of binding thymic stromal lymphopoietin
SI2370463T1 (sl) 2008-11-26 2017-01-31 Amgen Inc. Stabilizirana varianta IIB receptorja aktivina
EP2213682A1 (en) 2009-01-30 2010-08-04 Institut Curie TSLP promotes immune evasion and persistence of viruses
MY162511A (en) 2009-11-04 2017-06-15 Merck Sharp & Dohme Engineered anti-tslp antibody
PE20142114A1 (es) 2011-12-19 2015-01-04 Amgen Inc Polipeptidos de receptores de activina variantes, solos o en combinacion con quimioterapia, y sus usos
AR090915A1 (es) 2012-05-04 2014-12-17 Intervet Int Bv Proteina de fusion de proteina linfopoyetina estromal timica canina con la region fc de igg
US9592223B2 (en) 2012-11-09 2017-03-14 Cornell University Small molecule inhibitors of MALT1
UY35148A (es) 2012-11-21 2014-05-30 Amgen Inc Immunoglobulinas heterodiméricas
EA201591423A1 (ru) 2013-02-01 2016-01-29 Санта Мария Биотерапевтикс, Инк. Введение антитела к активину-а пациентам
US9708375B2 (en) 2013-03-15 2017-07-18 Amgen Inc. Inhibitory polypeptides specific to WNT inhibitors
EP2981280A2 (en) * 2013-04-04 2016-02-10 IEO - Istituto Europeo di Oncologia Srl Thymic stromal lymphopoietin fragments and uses thereof
AU2014318017B2 (en) 2013-09-05 2020-02-06 Amgen Inc. Fc-containing molecules exhibiting predictable, consistent, and reproducible glycoform profiles
EP3143404B1 (en) 2014-05-16 2018-08-29 Amgen Inc. Assay for detecting th1 and th2 cell populations
MX2016016281A (es) 2014-06-13 2017-03-31 Santa Maria Biotherapeutics Inc Polipeptidos receptores formulados y metodos relacionados.
WO2016148437A1 (ko) * 2015-03-17 2016-09-22 고려대학교 산학협력단 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물
KR101843248B1 (ko) 2015-03-17 2018-03-29 고려대학교 세종산학협력단 흉선 기질 림프단백질 매개 신호전달을 제어하는 펩타이드 유도체 및 이를 포함하는 알러지 및 천식 질환 예방 및 치료용 약학 조성물
UY36889A (es) 2015-09-09 2017-04-28 Novartis Ag Moléculas de unión a linfopoyetina estromal timica (tslp) y métodos de uso de las moléculas
BR112018003326A2 (pt) 2015-09-09 2018-09-18 Novartis Ag anticorpos de ligação de linfopoietina estromal tímica (tslp) e métodos de uso dos anticorpos
EP3596225A1 (en) 2017-03-14 2020-01-22 Amgen Inc. Control of total afucosylated glycoforms of antibodies produced in cell culture
CN111954719A (zh) 2018-03-26 2020-11-17 美国安进公司 细胞培养物中产生的抗体的总去岩藻糖基化糖型
CN109678957B (zh) * 2018-12-06 2021-04-06 浙江工业大学 一种抗人tslp单克隆抗体及其制备与应用
KR102156335B1 (ko) * 2018-12-28 2020-09-16 (주)메디톡스 외래 단백질을 발현하는 미생물, 및 그의 용도
AU2020355251A1 (en) 2019-09-26 2022-04-21 Amgen Inc. Methods of producing antibody compositions
US20230273126A1 (en) 2020-06-04 2023-08-31 Amgen Inc. Assessment of cleaning procedures of a biotherapeutic manufacturing process
CA3197930A1 (en) 2020-10-15 2022-04-21 Amgen Inc. Relative unpaired glycans in antibody production methods
EP4352094A1 (en) 2021-06-07 2024-04-17 Amgen Inc. Using fucosidase to control afucosylation level of glycosylated proteins
CA3233279A1 (en) 2021-10-05 2023-04-13 Amgen Inc. Fc-gamma receptor ii binding and glycan content
WO2023215725A1 (en) 2022-05-02 2023-11-09 Fred Hutchinson Cancer Center Compositions and methods for cellular immunotherapy

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5011912A (en) * 1986-12-19 1991-04-30 Immunex Corporation Hybridoma and monoclonal antibody for use in an immunoaffinity purification system
JPH07509223A (ja) 1992-04-30 1995-10-12 アムジェン インコーポレイテッド インターロイキン−１媒介疾患および腫瘍壊死因子媒介疾患の治療方法
WO1995000103A2 (en) 1993-06-15 1995-01-05 Il-Yang Pharm. Co., Ltd. Anti-sense oligodeoxynucleotide to fibrogenic cytokines and use thereof
GB9702944D0 (en) 1997-02-13 1997-04-02 Univ Manchester Reducing fibrosis
US6982320B2 (en) 1998-03-19 2006-01-03 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
EP1093457B8 (en) 1998-03-19 2011-02-02 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
US6844170B1 (en) * 1998-03-19 2005-01-18 Human Genome Sciences, Inc. Cytokine receptor common gamma chain like
AU6246199A (en) * 1998-09-21 2000-04-10 Schering Corporation Human interleukin-b50, therapeutic uses
US20030099947A1 (en) * 1998-09-21 2003-05-29 Bazan J. Fernando Mammalian cytokines; related reagents and methods
WO2000029581A1 (en) 1998-11-13 2000-05-25 Immunex Corporation Human tslp dna and polypeptides
WO2000039149A2 (en) 1998-12-30 2000-07-06 Millennium Pharmaceuticals, Inc. Secreted proteins and uses thereof
US20010021380A1 (en) 1999-04-19 2001-09-13 Pluenneke John D. Soluble tumor necrosis factor receptor treatment of medical disorders
EP2241328A1 (en) 2000-05-12 2010-10-20 Immunex Corporation Interleukin-1 inhibitors in the treatment of diseases
AU2001271624A1 (en) 2000-06-28 2002-01-08 Whitehead Institute For Biomedical Research Thymic stromal lymphopoietin receptor molecules and uses thereof
WO2002000724A2 (en) 2000-06-28 2002-01-03 Amgen, Inc. Thymic stromal lymphopoietin receptor molecules and uses thereof
PT2311869E (pt) * 2002-02-01 2013-03-04 Merck Sharp & Dohme Utilização de reagentes relacionados com citoquinas de mamíferos
HRP20020453A2 (en) 2002-05-23 2003-12-31 Pliva D D 1,3-diaza-dibenzoazulen as inhibitor of production of tumor necrosis factors and intermediate for preparation thereof
NZ593428A (en) 2002-09-06 2013-01-25 Amgen Inc Therapeutic human anti-il-1r1 monoclonal antibody
WO2005007186A1 (en) 2003-07-18 2005-01-27 Schering Corporation Treatment and diagnosis of neoplasms using thymic stromal lymphopoietin
US20050249712A1 (en) * 2004-03-23 2005-11-10 The Government Of The Usa As Represented By The Secretary Of The Dept. Of Health & Human Services Methods for use of TSLP and agonists and antagonists thereof
WO2006023791A2 (en) 2004-08-20 2006-03-02 Amgen Inc. Methods and compositions for treating allergic inflammation
RU2486202C2 (ru) 2006-01-13 2013-06-27 Айрм Ллк Антитела к рецептору тимусного стромального лимфопоэтина
GB0603683D0 (en) 2006-02-23 2006-04-05 Novartis Ag Organic compounds
AU2007334499B2 (en) 2006-12-14 2014-04-24 Merck Sharp & Dohme Corp. Engineered anti-TSLP antibody
EP2170957A1 (en) 2007-06-20 2010-04-07 Irm, Llc Methods and compositions for treating allergic diseases
WO2012141199A1 (ja) † 2011-04-11 2012-10-18 クラリオン株式会社 位置算出方法及び位置算出装置

Also Published As

Publication number Publication date
US9346870B2 (en) 2016-05-24
US20120014961A1 (en) 2012-01-19
DE69936105D1 (de) 2007-06-28
ES2288036T5 (es) 2017-07-06
US8444979B2 (en) 2013-05-21
JP2002530079A (ja) 2002-09-17
IL143034A0 (en) 2002-04-21
CA2349762A1 (en) 2000-05-25
JP2010088445A (ja) 2010-04-22
US7304144B2 (en) 2007-12-04
EP1129190B1 (en) 2007-05-16
US7405058B2 (en) 2008-07-29
JP2013078331A (ja) 2013-05-02
ES2288036T3 (es) 2007-12-16
IL143034A (en) 2009-07-20
US20100266601A1 (en) 2010-10-21
US20060223754A1 (en) 2006-10-05
DE69936105T2 (de) 2008-01-24
US20150005226A1 (en) 2015-01-01
US20020146819A1 (en) 2002-10-10
EP1129190B2 (en) 2017-01-11
ATE362534T2 (de) 2007-06-15
AU1726600A (en) 2000-06-05
US20130225490A1 (en) 2013-08-29
US7786271B2 (en) 2010-08-31
IL195812A0 (en) 2011-08-01
IL195812A (en) 2012-04-30
US20030181360A1 (en) 2003-09-25
DE69936105T3 (de) 2017-07-27
US20090017034A1 (en) 2009-01-15
DK1129190T4 (da) 2017-04-03
US6555520B2 (en) 2003-04-29
WO2000029581A1 (en) 2000-05-25
NZ512105A (en) 2004-04-30
PT1129190E (pt) 2007-08-08
JP4454859B2 (ja) 2010-04-21
JP5632155B2 (ja) 2014-11-26
EP1129190A1 (en) 2001-09-05
CA2349762C (en) 2013-12-24
AU755562B2 (en) 2002-12-12
CY1106806T1 (el) 2012-05-23

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