WO2002012475A3 - C1q-related factor, homologous polypeptides and therapeutic uses thereof - Google Patents

C1q-related factor, homologous polypeptides and therapeutic uses thereof Download PDF

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Publication number
WO2002012475A3
WO2002012475A3 PCT/US2001/021109 US0121109W WO0212475A3 WO 2002012475 A3 WO2002012475 A3 WO 2002012475A3 US 0121109 W US0121109 W US 0121109W WO 0212475 A3 WO0212475 A3 WO 0212475A3
Authority
WO
WIPO (PCT)
Prior art keywords
therapeutic uses
homologous polypeptides
related factor
cerebellin
similarity
Prior art date
Application number
PCT/US2001/021109
Other languages
French (fr)
Other versions
WO2002012475A2 (en
Inventor
Eric Wen Su
Original Assignee
Lilly Co Eli
Eric Wen Su
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Eric Wen Su filed Critical Lilly Co Eli
Priority to EP01958853A priority Critical patent/EP1328632A2/en
Priority to AU2001280464A priority patent/AU2001280464A1/en
Publication of WO2002012475A2 publication Critical patent/WO2002012475A2/en
Publication of WO2002012475A3 publication Critical patent/WO2002012475A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/472—Complement proteins, e.g. anaphylatoxin, C3a, C5a

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention provides nucleic acid sequences encoding novel human CRF-like protein having some similarity to cerebellin. These novel nucleic acids are useful for constructing the claimed DNA vectors and host cells of the invention and for preparing the claimed recombinant proteins and antibodies.
PCT/US2001/021109 2000-08-04 2001-07-23 C1q-related factor, homologous polypeptides and therapeutic uses thereof WO2002012475A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01958853A EP1328632A2 (en) 2000-08-04 2001-07-23 C1q-related factor, homologous polypeptides and therapeutic uses thereof
AU2001280464A AU2001280464A1 (en) 2000-08-04 2001-07-23 C1q-related factor, homologous polypeptides and therapeutic uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22323600P 2000-08-04 2000-08-04
US60/223,236 2000-08-04

Publications (2)

Publication Number Publication Date
WO2002012475A2 WO2002012475A2 (en) 2002-02-14
WO2002012475A3 true WO2002012475A3 (en) 2003-05-15

Family

ID=22835644

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/021109 WO2002012475A2 (en) 2000-08-04 2001-07-23 C1q-related factor, homologous polypeptides and therapeutic uses thereof

Country Status (3)

Country Link
EP (1) EP1328632A2 (en)
AU (1) AU2001280464A1 (en)
WO (1) WO2002012475A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002216671A1 (en) * 2000-11-29 2002-06-11 Zymogenetics Inc. Adipocyte complement related protein zacrp12
AU2014324884B2 (en) 2013-09-25 2020-03-26 Cytomx Therapeutics, Inc Matrix metalloproteinase substrates and other cleavable moieties and methods of use thereof
DK3628328T3 (en) 2014-01-31 2022-12-05 Cytomx Therapeutics Inc MATRIPTASE AND U PLASMINOGEN ACTIVATOR SUBSTRATES AND OTHER CLEAVABLE PARTS AND METHODS OF USING THEREOF
MA41374A (en) 2015-01-20 2017-11-28 Cytomx Therapeutics Inc MATRIX METALLOPROTEASE CLIVABLE AND SERINE PROTEASE CLIVABLE SUBSTRATES AND METHODS OF USE THEREOF

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042576A1 (en) * 1998-02-23 1999-08-26 Smithkline Beecham Plc Cerebellin-2 related polypeptides and dna coding therefor

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999042576A1 (en) * 1998-02-23 1999-08-26 Smithkline Beecham Plc Cerebellin-2 related polypeptides and dna coding therefor

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BERUBE NATHALIE G ET AL: "Cloning and characterization of CRF, a novel C1q-related factor, expressed in areas of the brain involved in motor function.", MOLECULAR BRAIN RESEARCH, vol. 63, no. 2, 8 January 1999 (1999-01-08), pages 233 - 240, XP002205214, ISSN: 0169-328X *
DATABASE EMBL [online] EBI, Hinxton, UK; 14 December 1999 (1999-12-14), "Homo sapiens BAC clone RP11-17N4 from 2, complete sequence.", XP002205216, Database accession no. AC016673 *
See also references of EP1328632A2 *
URADE Y ET AL: "PRECEREBELLIN IS A CEREBELLUM-SPECIFIC PROTEIN WITH SIMILARITY TO THE GLOBULAR DOMAIN OF COMPLEMENT C1Q B CHAIN", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 88, no. 3, 1991, 1991, pages 1069 - 1073, XP002205215, ISSN: 0027-8424 *
WADA C & OHTANI ET AL: "Molecular cloning of rat cerebellin-like protein cDNA which encodes a novel membrane-associated glycoprotein", MOLECULAR BRAIN RESEARCH, ELSEVIER SCIENCE BV, AMSTERDAM, NL, vol. 9, no. 1/2, January 1991 (1991-01-01), pages 71 - 77, XP002103511, ISSN: 0169-328X *

Also Published As

Publication number Publication date
EP1328632A2 (en) 2003-07-23
WO2002012475A2 (en) 2002-02-14
AU2001280464A1 (en) 2002-02-18

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