DK2900675T3 - Fremgangsmåde til fremstilling af et thienopyrimidinderivat - Google Patents
Fremgangsmåde til fremstilling af et thienopyrimidinderivat Download PDFInfo
- Publication number
- DK2900675T3 DK2900675T3 DK13779938.3T DK13779938T DK2900675T3 DK 2900675 T3 DK2900675 T3 DK 2900675T3 DK 13779938 T DK13779938 T DK 13779938T DK 2900675 T3 DK2900675 T3 DK 2900675T3
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- manufacture
- thienopyrimidine derivative
- thienopyrimidine
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2012217679 | 2012-09-28 | ||
| PCT/JP2013/077013 WO2014051164A2 (en) | 2012-09-28 | 2013-09-27 | Production method of thienopyrimidine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2900675T3 true DK2900675T3 (da) | 2019-06-03 |
Family
ID=49448235
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18185835.8T DK3415517T3 (da) | 2012-09-28 | 2013-09-27 | Krystallinsk form af 1-(4-1-(2,6-difluorbenzyl)-5-dimethylaminomethyl-3-(6- methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno(2,3-d)-pyrimidin- 6yl)phenyl)-3-methoxyurea |
| DK13779938.3T DK2900675T3 (da) | 2012-09-28 | 2013-09-27 | Fremgangsmåde til fremstilling af et thienopyrimidinderivat |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK18185835.8T DK3415517T3 (da) | 2012-09-28 | 2013-09-27 | Krystallinsk form af 1-(4-1-(2,6-difluorbenzyl)-5-dimethylaminomethyl-3-(6- methoxypyridazin-3-yl)-2,4-dioxo-1,2,3,4-tetrahydrothieno(2,3-d)-pyrimidin- 6yl)phenyl)-3-methoxyurea |
Country Status (20)
| Country | Link |
|---|---|
| US (8) | US9758528B2 (da) |
| EP (3) | EP2900675B1 (da) |
| JP (1) | JP6250564B2 (da) |
| CN (3) | CN104703992B (da) |
| AR (1) | AR092707A1 (da) |
| CA (1) | CA2881132C (da) |
| CY (1) | CY1121641T1 (da) |
| DK (2) | DK3415517T3 (da) |
| ES (2) | ES2724206T3 (da) |
| HR (2) | HRP20220622T1 (da) |
| HU (2) | HUE059077T2 (da) |
| LT (2) | LT2900675T (da) |
| PL (2) | PL3415517T3 (da) |
| PT (2) | PT2900675T (da) |
| RS (2) | RS63199B1 (da) |
| SI (2) | SI2900675T1 (da) |
| TR (1) | TR201906318T4 (da) |
| TW (3) | TWI641611B (da) |
| UY (1) | UY35058A (da) |
| WO (1) | WO2014051164A2 (da) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2900675T1 (sl) | 2012-09-28 | 2019-06-28 | Takeda Pharmaceutical Company Limited | Postopek za pridobivanje tienopirimidin derivata |
| MY180680A (en) | 2015-02-26 | 2020-12-06 | Takeda Pharmaceuticals Co | Solid preparation |
| CN110312512B (zh) | 2016-09-30 | 2023-05-09 | 梦欧文科学有限责任公司 | 用于治疗子宫肌瘤和子宫内膜异位症的方法 |
| WO2018060463A2 (en) | 2016-09-30 | 2018-04-05 | Myovant Sciences Gmbh | Treatment of prostate cancer |
| US10787451B2 (en) * | 2016-11-14 | 2020-09-29 | Jiangsu Hengrui Medicine Co., Ltd. | Crystalline form of GnRH receptor antagonist and preparation method therefor |
| KR20200027481A (ko) | 2017-06-05 | 2020-03-12 | 옵스에파 에스에이 | 자궁내막증의 치료를 위한 고나도트로핀 방출호르몬 길항제 투약요법 |
| CN107188855A (zh) * | 2017-07-14 | 2017-09-22 | 常州工程职业技术学院 | 一种3‑氨基‑6甲氧基哒嗪的制备方法 |
| US11306104B2 (en) | 2018-03-14 | 2022-04-19 | Teva Pharmaceuticals International Gmbh | Solid state forms of Relugolix |
| EP3666776A1 (en) | 2018-12-11 | 2020-06-17 | Sandoz AG | Hydrate of a gonadotropin-releasing hormone receptor antagonist |
| EP3969455A4 (en) * | 2019-05-15 | 2023-07-05 | Dr. Reddy's Laboratories Limited | AMORPHOUS AND CRYSTALLINE FORMS OF RELUGOLIX |
| CN110194776B (zh) * | 2019-06-27 | 2021-05-28 | 四川伊诺达博医药科技有限公司 | 一种瑞卢戈利的合成方法 |
| EP4004001A4 (en) * | 2019-07-29 | 2023-08-30 | Sunshine Lake Pharma Co., Ltd. | SUBSTITUTED PYRIMIDINEONE COMPOUNDS AND USES THEREOF |
| JP2022542159A (ja) * | 2019-08-02 | 2022-09-29 | ジョンソン、マッセイ、パブリック、リミテッド、カンパニー | 固体形態レルゴリクス（Ｒｅｌｕｇｏｌｉｘ） |
| CN112321602A (zh) * | 2019-08-05 | 2021-02-05 | 苏州鹏旭医药科技有限公司 | 一种瑞卢戈利药物中间体的制备方法 |
| CN112390812A (zh) * | 2019-08-14 | 2021-02-23 | 苏州鹏旭医药科技有限公司 | 瑞卢戈利化合物的晶型和无定型固体及其制备方法 |
| CN112771052B (zh) * | 2019-08-21 | 2023-04-07 | 深圳仁泰医药科技有限公司 | 促性腺素释放激素拮抗剂的晶型及其制备方法和用途 |
| JP2022551316A (ja) * | 2019-10-10 | 2022-12-08 | ミオバント サイエンシズ ゲーエムベーハー | Ｎ－（４－（１－（２，６－ジフルオロベンジル）－５－（（ジメチルアミノ）メチル）－３－（６－メトキシ－３－ピリダジニル）－２，４－ジオキソ－１，２，３，４－テトラヒドロチエノ［２，３－ｄ］ピリミジン－６－イル）フェニル）－Ｎ’－メトキシ尿素の結晶形 |
| WO2021069700A1 (en) * | 2019-10-10 | 2021-04-15 | Myovant Sciences Gmbh | Crystalline solvated forms of n-(4-(1-(2,6-difluorobenzyl)-5- ((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4- tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea |
| CN112745304A (zh) * | 2019-10-29 | 2021-05-04 | 上海度德医药科技有限公司 | 一种Relugolix的制备方法及中间体化合物 |
| CN111423452B (zh) * | 2020-03-26 | 2023-08-22 | 江西青峰药业有限公司 | 瑞卢戈利的中间体及其制备方法和应用 |
| CN113444105A (zh) * | 2020-03-27 | 2021-09-28 | 南京海润医药有限公司 | 一种Relugolix的制备方法 |
| CN111333633B (zh) * | 2020-04-01 | 2023-10-20 | 江西科睿药业有限公司 | 一种瑞卢戈利的中间体化合物及其制备方法和用途 |
| CN111574534B (zh) * | 2020-05-25 | 2021-06-04 | 东莞市东阳光新药研发有限公司 | 苯基取代的噻吩并[2,3-d]嘧啶-2,4(1H,3H)-二酮类化合物及其用途 |
| CN115666531A (zh) | 2020-05-29 | 2023-01-31 | 梦欧文科学有限责任公司 | ***释放激素拮抗剂的组合固体口服剂型 |
| US11655256B1 (en) | 2020-11-06 | 2023-05-23 | Macfarlan Smith Limited | Processes for making a solid-state form of relugolix |
| JP2023549196A (ja) | 2020-11-11 | 2023-11-22 | ミオバント サイエンシズ ゲーエムベーハー | レルゴリクスの投与方法 |
| CN112552312B (zh) * | 2020-12-07 | 2022-08-05 | 杭州科巢生物科技有限公司 | 一种瑞卢戈利或其盐的合成方法 |
| CN114685468A (zh) * | 2020-12-25 | 2022-07-01 | 成都硕德药业有限公司 | 用于治疗子宫肌瘤的药物的中间体化合物及其制备方法 |
| CN113620972A (zh) * | 2021-02-02 | 2021-11-09 | 奥锐特药业(天津)有限公司 | 瑞卢戈利新晶型及其制备方法 |
| CN114907370B (zh) | 2021-02-10 | 2023-11-03 | 奥锐特药业(天津)有限公司 | 高纯度的噻吩并嘧啶化合物及其制备方法 |
| CN115073491A (zh) * | 2021-03-12 | 2022-09-20 | 上海医药工业研究院 | 一种瑞卢戈利中间体、其制备方法及其应用 |
| WO2022214645A1 (en) | 2021-04-09 | 2022-10-13 | Farmhispania Group, S.L. | Processes and intermediates for the preparation of relugolix |
| CN115594688B (zh) * | 2021-06-28 | 2023-11-17 | 成都倍特药业股份有限公司 | 瑞卢戈利中间体的制备方法 |
| WO2023066941A1 (en) | 2021-10-18 | 2023-04-27 | Myovant Sciences Gmbh | Crystalline form of an ethanol solvate of n-(4-(1-(2,6-difluorobenzyl)-5-((dimethylamino)methyl)-3-(6-methoxy-3-pyridazinyl)-2,4-dioxo-1,2,3,4-tetrahydrothieno[2,3-d]pyrimidin-6-yl)phenyl)-n'-methoxyurea |
| CN114230576A (zh) * | 2021-12-21 | 2022-03-25 | 伊诺药物研究(南京)有限公司 | 一种瑞卢戈利的制备方法 |
| WO2023119333A1 (en) * | 2021-12-25 | 2023-06-29 | Dr. Reddy’S Laboratories Limited | Process for preparation of relugolix and its intermediates |
| CN114409629B (zh) * | 2022-02-22 | 2023-12-29 | 浙江科聚生物医药有限公司 | 一种高纯度Relugolix关键中间体的制备方法及应用 |
| CN114790189B (zh) * | 2022-02-24 | 2023-06-09 | 海化生命(厦门)科技有限公司 | 瑞卢戈利中间体的制备方法 |
| CN114755320A (zh) * | 2022-03-17 | 2022-07-15 | 南京方生和医药科技有限公司 | 一种3-氨基-6-甲氧基哒嗪有关物质的检测方法 |
| WO2023194924A1 (en) * | 2022-04-08 | 2023-10-12 | Glenmark Life Sciences Limited | Process for preparation of relugolix |
| CN114621249B (zh) * | 2022-04-27 | 2024-01-26 | 江苏慧聚药业股份有限公司 | 瑞卢戈利关键中间体的制备 |
| TW202345840A (zh) * | 2022-05-05 | 2023-12-01 | 台灣神隆股份有限公司 | 瑞格列克及其中間體的製備方法 |
| CN117285506A (zh) * | 2022-07-14 | 2023-12-26 | 江西同和药业股份有限公司 | 一种瑞卢戈利中间体及其制备方法 |
| CN115594689B (zh) * | 2022-07-14 | 2024-03-19 | 江西同和药业股份有限公司 | 一种瑞卢戈利中间体、一种瑞卢戈利的合成方法 |
| CN115417883A (zh) * | 2022-09-16 | 2022-12-02 | 浙江科聚生物医药有限公司 | 一种瑞卢戈利的晶型及其制备方法 |
| WO2024069492A1 (en) | 2022-09-29 | 2024-04-04 | Macfarlan Smith Limited | Processes for the preparation and manufacture of relugolix |
| CN115650950A (zh) * | 2022-11-03 | 2023-01-31 | 江西同和药业股份有限公司 | 一种瑞卢戈利中间体及其制备方法以及一种酰胺缩合方法 |
| WO2024126674A1 (en) | 2022-12-15 | 2024-06-20 | Medichem, S.A. | Process for the preparation of relugolix |
| CN115650965B (zh) * | 2022-12-26 | 2023-03-31 | 南京威凯尔生物医药科技有限公司 | 一种瑞卢戈利关键中间体的制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5116436B1 (da) * | 1971-05-31 | 1976-05-24 | ||
| EP0237289A3 (en) | 1986-03-14 | 1988-07-27 | Takeda Chemical Industries, Ltd. | Pyrazolo [3,4-d] pyrimidine derivatives, their production and use |
| US5312958A (en) | 1992-01-31 | 1994-05-17 | Takeda Chemical Industries, Ltd. | Process for producing 4-bromomethylbiphenyl compounds |
| JP2859791B2 (ja) * | 1992-01-31 | 1999-02-24 | 吉富製薬株式会社 | ４−ブロモメチルビフェニル化合物の製造法 |
| JPH10298156A (ja) * | 1997-04-28 | 1998-11-10 | Nippon Nohyaku Co Ltd | 置換ハロメチルフェニルカルバミド酸エステル類の製造方法 |
| TWI225863B (en) * | 1999-03-24 | 2005-01-01 | Takeda Chemical Industries Ltd | Thienopyrimidine compounds, their production and use |
| RU2233284C2 (ru) | 1999-03-24 | 2004-07-27 | Такеда Кемикал Индастриз, Лтд. | Тиенопиримидиновые производные, способ их получения, фармацевтическая композиция и способ антагонизации гонадотропин-рилизинг гормона |
| JP2001316391A (ja) * | 2000-02-29 | 2001-11-13 | Takeda Chem Ind Ltd | チエノピリミジン誘導体の製造法 |
| AU2001234188A1 (en) | 2000-02-29 | 2001-09-12 | Takeda Chemical Industries Ltd. | Processes for the production of thienopyrimidine derivatives |
| GB2361917A (en) * | 2000-05-04 | 2001-11-07 | Astrazeneca Ab | Novel thieno[2,3-d]pyrimidinediones |
| JP2002068044A (ja) | 2000-09-04 | 2002-03-08 | Yamaha Motor Co Ltd | 自動二輪車用ハンドルシート |
| JP2002088044A (ja) * | 2000-09-14 | 2002-03-27 | Sumitomo Seika Chem Co Ltd | ４’−ブロモメチル−２−シアノビフェニルの製造方法 |
| ES2252540T3 (es) | 2001-09-04 | 2006-05-16 | Akzo Nobel N.V. | Tieno (2,3-d) pirimidinas glicino-sustituidas con actividad agonistas combinada lh y fsh. |
| US7569570B2 (en) * | 2002-01-30 | 2009-08-04 | Takeda Pharmaceutical Company Limited | Thienopyrimidines, process for preparing the same and use thereof |
| KR20050084311A (ko) | 2002-12-20 | 2005-08-26 | 코닌클리즈케 필립스 일렉트로닉스 엔.브이. | 비디오 이미지 개선 방법 및 이를 이용한 비디오 디코더,셋탑 박스, 텔레비전 |
| ES2217956B1 (es) * | 2003-01-23 | 2006-04-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de 4-aminotieno(2,3-d)pirimidin-6-carbonitrilo. |
| US7300935B2 (en) | 2003-01-29 | 2007-11-27 | Takeda Pharmaceutical Company | Thienopyrimidine compounds and use thereof |
| US7947691B2 (en) * | 2004-07-21 | 2011-05-24 | Athersys, Inc. | Cyclic n-hydroxy imides as inhibitors of flap endonuclease and uses thereof |
| RU2007115517A (ru) | 2004-10-25 | 2008-10-27 | Нихон Нохияку Ко. | Гербицидная композиция для пастбищно-выпасного хозяйства на холмах и способ борьбы с сорняками |
| ES2494842T3 (es) * | 2005-07-22 | 2014-09-16 | Takeda Pharmaceutical Company Limited | Agente que previene la ovulación precoz |
| EP2329823A4 (en) | 2008-09-03 | 2013-04-03 | Takeda Pharmaceutical | METHOD FOR IMPROVING CAPACITY OF PREPARATION TO BE ABSORBED AND PREPARATION WHICH CAPACITY TO BE ABSORBED IS IMPROVED |
| CU24177B1 (es) * | 2011-02-23 | 2016-04-25 | Lupin Ltd | Derivados de heteroarilo como moduladores de nachr alfa 7 |
| JP2012217679A (ja) | 2011-04-11 | 2012-11-12 | Okumura Yu-Ki Co Ltd | パチンコ遊技機 |
| SI2900675T1 (sl) | 2012-09-28 | 2019-06-28 | Takeda Pharmaceutical Company Limited | Postopek za pridobivanje tienopirimidin derivata |
| MY180680A (en) | 2015-02-26 | 2020-12-06 | Takeda Pharmaceuticals Co | Solid preparation |
-
2013
- 2013-09-27 SI SI201331414T patent/SI2900675T1/sl unknown
- 2013-09-27 TW TW106130632A patent/TWI641611B/zh active
- 2013-09-27 ES ES13779938T patent/ES2724206T3/es active Active
- 2013-09-27 DK DK18185835.8T patent/DK3415517T3/da active
- 2013-09-27 PT PT13779938T patent/PT2900675T/pt unknown
- 2013-09-27 ES ES18185835T patent/ES2913753T3/es active Active
- 2013-09-27 RS RS20220449A patent/RS63199B1/sr unknown
- 2013-09-27 WO PCT/JP2013/077013 patent/WO2014051164A2/en active Application Filing
- 2013-09-27 HR HRP20220622TT patent/HRP20220622T1/hr unknown
- 2013-09-27 EP EP13779938.3A patent/EP2900675B1/en active Active
- 2013-09-27 PT PT181858358T patent/PT3415517T/pt unknown
- 2013-09-27 DK DK13779938.3T patent/DK2900675T3/da active
- 2013-09-27 AR ARP130103480A patent/AR092707A1/es unknown
- 2013-09-27 US US14/432,188 patent/US9758528B2/en active Active
- 2013-09-27 JP JP2014557263A patent/JP6250564B2/ja active Active
- 2013-09-27 TW TW102134983A patent/TWI602819B/zh active
- 2013-09-27 LT LTEP13779938.3T patent/LT2900675T/lt unknown
- 2013-09-27 PL PL18185835T patent/PL3415517T3/pl unknown
- 2013-09-27 CA CA2881132A patent/CA2881132C/en not_active Expired - Fee Related
- 2013-09-27 UY UY0001035058A patent/UY35058A/es not_active Application Discontinuation
- 2013-09-27 EP EP22168256.0A patent/EP4119564A1/en active Pending
- 2013-09-27 SI SI201331988T patent/SI3415517T1/sl unknown
- 2013-09-27 LT LTEP18185835.8T patent/LT3415517T/lt unknown
- 2013-09-27 TW TW107136006A patent/TWI663171B/zh active
- 2013-09-27 CN CN201380051107.2A patent/CN104703992B/zh active Active
- 2013-09-27 PL PL13779938T patent/PL2900675T3/pl unknown
- 2013-09-27 CN CN201811130716.8A patent/CN109053766B/zh active Active
- 2013-09-27 HU HUE18185835A patent/HUE059077T2/hu unknown
- 2013-09-27 TR TR2019/06318T patent/TR201906318T4/tr unknown
- 2013-09-27 RS RS20190473A patent/RS58703B1/sr unknown
- 2013-09-27 CN CN202110609164.4A patent/CN113372358B/zh active Active
- 2013-09-27 HU HUE13779938A patent/HUE044048T2/hu unknown
- 2013-09-27 EP EP18185835.8A patent/EP3415517B1/en active Active
-
2017
- 2017-04-07 US US15/481,505 patent/US10150778B2/en active Active
-
2018
- 2018-07-12 US US16/034,002 patent/US10464945B2/en active Active
- 2018-08-29 US US16/116,804 patent/US10544160B2/en active Active
-
2019
- 2019-04-17 HR HRP20190729TT patent/HRP20190729T1/hr unknown
- 2019-05-21 CY CY20191100544T patent/CY1121641T1/el unknown
- 2019-12-11 US US16/710,390 patent/US11053257B2/en active Active
-
2021
- 2021-06-16 US US17/349,584 patent/US11731983B2/en active Active
-
2022
- 2022-03-14 US US17/694,635 patent/US11795178B2/en active Active
-
2023
- 2023-03-15 US US18/121,886 patent/US20230212184A1/en active Pending
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK2900675T3 (da) | Fremgangsmåde til fremstilling af et thienopyrimidinderivat | |
| DK3225604T3 (da) | Fremgangsmåde til fremstilling af flerlagsruder | |
| DK3454346T3 (da) | Anordning til cylotronfremstilling af technetium-99m | |
| DK3470397T3 (da) | Krystallinske former af en prolylhydroxylaseinhibitor | |
| DK3257546T3 (da) | Fremgangsmåde til fremstilling af et brugsklart kateter | |
| DK2953904T3 (da) | Fremgangsmåde til kontrolleret fremstilling af et biocid | |
| DK2639050T3 (da) | Fremgangsmåde til fremstilling af en artikel ved formning | |
| DK2730878T3 (da) | Pladestak og fremgangsmåde til fremstilling af en pladestak | |
| DK2906696T4 (da) | Fremgangsmåder til modulering af c9orf72-ekspression | |
| DK3824991T3 (da) | Fremgangsmåde til forberedelse af lithiumsulfat | |
| DK2736837T3 (da) | Fremgangsmåde til fremstilling af nanosiliciumtråde | |
| DK2718404T3 (da) | Fremgangsmåde til fremstilling af flydende carbonhydrider | |
| DK2814849T3 (da) | Fremgangsmåde til fremstilling af cyclodextrin-derivater | |
| DK3210978T3 (da) | Fremgangsmåde til fremstilling af acesulfamkalium | |
| DK2623288T3 (da) | Fremgangsmåde til fremstilling af formstøbte skumdele | |
| DK2895033T3 (da) | Mønsterdannelse til konstruerbart redskab | |
| DK2595948T3 (da) | Fremgangsmåde til fremstilling af ingenol-3-angelat | |
| DK3399035T3 (da) | Fremgangsmåde til fremstilling af et beriget bibliotek | |
| DK2822965T3 (da) | FREMGANGSMÅDE TIL BERIGELSE AF IgA | |
| DK2919777T3 (da) | Transmukosal afgivelse af tocotrienol | |
| DK2836460T3 (da) | Fremgangsmåde til fremstilling af graphen | |
| DK2938747T3 (da) | Fremgangsmåde til fremstilling af en mycoplasma vaccine | |
| DK2685204T3 (da) | Indretning til montering af en sigteindretning på et håndvåben | |
| DK2908724T3 (da) | Fremgangsmåde til at følge udviklingen af en hjernelæsion | |
| DK2811835T3 (da) | Fremgangsmåde til fremstilling af bagværk |