DK3399035T3 - Fremgangsmåde til fremstilling af et beriget bibliotek - Google Patents

Fremgangsmåde til fremstilling af et beriget bibliotek Download PDF

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Publication number
DK3399035T3
DK3399035T3 DK18161280.5T DK18161280T DK3399035T3 DK 3399035 T3 DK3399035 T3 DK 3399035T3 DK 18161280 T DK18161280 T DK 18161280T DK 3399035 T3 DK3399035 T3 DK 3399035T3
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DK
Denmark
Prior art keywords
procedure
making
enriched library
enriched
library
Prior art date
Application number
DK18161280.5T
Other languages
English (en)
Inventor
Nils Jakob Vest Hansen
Allan Beck Christensen
Leif Kongskov Larsen
Lars Kolster Petersen
Judith Rasmussen-Dietvorst
Tara Heitner Hansen
Johan Holmkvist
Peter Blakskjaer
Frank Abildgaard Sløk
Original Assignee
Vipergen Aps
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Vipergen Aps filed Critical Vipergen Aps
Application granted granted Critical
Publication of DK3399035T3 publication Critical patent/DK3399035T3/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1075Isolating an individual clone by screening libraries by coupling phenotype to genotype, not provided for in other groups of this subclass
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1068Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis

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  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK18161280.5T 2010-09-27 2011-09-01 Fremgangsmåde til fremstilling af et beriget bibliotek DK3399035T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP10180435 2010-09-27
EP11749853.5A EP2622073B1 (en) 2010-09-27 2011-09-01 A method for making an enriched library

Publications (1)

Publication Number Publication Date
DK3399035T3 true DK3399035T3 (da) 2021-05-17

Family

ID=43629282

Family Applications (2)

Application Number Title Priority Date Filing Date
DK11749853.5T DK2622073T5 (da) 2010-09-27 2011-09-01 Fremgangsmåde til fremstilling af et beriget bibliotek
DK18161280.5T DK3399035T3 (da) 2010-09-27 2011-09-01 Fremgangsmåde til fremstilling af et beriget bibliotek

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK11749853.5T DK2622073T5 (da) 2010-09-27 2011-09-01 Fremgangsmåde til fremstilling af et beriget bibliotek

Country Status (8)

Country Link
US (2) US20130288929A1 (da)
EP (2) EP3399035B1 (da)
JP (2) JP6193761B2 (da)
CN (1) CN103119165B (da)
CA (1) CA2808656C (da)
DK (2) DK2622073T5 (da)
IL (1) IL224694B (da)
WO (1) WO2012041633A1 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2622073T5 (da) * 2010-09-27 2019-02-25 Vipergen Fremgangsmåde til fremstilling af et beriget bibliotek
WO2014088830A2 (en) * 2012-12-05 2014-06-12 The Regents Of The University Of California Screening of nucleic acid agents via particle display
CN104630202A (zh) * 2013-11-13 2015-05-20 北京大学 一种能够减小微量核酸物质整体扩增时产生偏倚的扩增方法
GB201420852D0 (en) * 2014-11-24 2015-01-07 Genevillage Kft Method
US11028427B2 (en) * 2015-08-18 2021-06-08 Purdue Research Foundation Systems and methods for proteomic activity analysis using DNA-encoded probes
KR102379048B1 (ko) 2016-05-02 2022-03-28 엔코디아, 인코포레이티드 암호화 핵산을 사용한 거대분자 분석
CN115820806A (zh) 2016-06-16 2023-03-21 哈斯达克科学公司 寡核苷酸指导和记录的编码探针分子的组合合成
EP3619340A4 (en) 2017-05-02 2021-01-20 Haystack Sciences Corporation MOLECULES FOR THE VERIFICATION OF OLIGONUCLEOTIDE DIRECTED COMBINATIONAL SYNTHESIS AND METHOD OF MANUFACTURING AND USING THEREOF
MX2020004559A (es) 2017-10-31 2020-10-05 Encodia Inc Kits para análisis utilizando codificación y/o etiqueta de ácido nucleico.
SG11202003664TA (en) 2017-11-30 2020-05-28 Arrakis Therapeutics Inc Nucleic acid-binding photoprobes and uses thereof
AU2020211270A1 (en) * 2019-01-22 2021-07-15 Vipergen Aps A method for screening of an in vitro display library within a cell
CA3138367A1 (en) 2019-04-30 2020-11-05 Encodia, Inc. Methods for preparing analytes and related kits
CN112941634B (zh) * 2019-12-10 2023-09-26 成都先导药物开发股份有限公司 通过dna编码化合物库筛选同时结合多个生物靶标的化合物的方法
US20240209350A1 (en) * 2021-04-26 2024-06-27 European Molecular Biology Laboratory High complexity microcompartment-based interaction screening

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
EP1123305A1 (en) 1998-10-19 2001-08-16 The Board Of Trustees Of The Leland Stanford Junior University Dna-templated combinatorial library chemistry
ATE335754T1 (de) 2001-03-19 2006-09-15 Harvard College Entwicklung neuer molekularer funktionen
WO2002103008A2 (en) 2001-06-20 2002-12-27 Nuevolution A/S Templated molecules and methods for using such molecules
DE602004023960D1 (de) * 2003-09-18 2009-12-17 Nuevolution As Methode zur Gewinnung struktureller Informationen kodierter Moleküle und zur Selektion von Verbindungen
MXPA06006863A (es) * 2003-12-17 2006-09-04 Praecis Pharm Inc Metodo para la sintesis de bibliotecas codificadas.
US7968287B2 (en) * 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
US20060099626A1 (en) * 2004-10-27 2006-05-11 Harbury Pehr B DNA-templated combinatorial library device and method for use
KR101411361B1 (ko) * 2004-11-08 2014-06-25 비퍼겐 에이피에스 구조적 핵산에 의해 가이드되는 화학적 합성
DE602005012319D1 (de) 2004-11-22 2009-02-26 Peter Birk Rasmussen Matrizengerichtete split-and-mix-synthese von bibliotheken kleiner moleküle
CN101617046A (zh) 2007-02-23 2009-12-30 新英格兰生物实验室公司 使用体外区室化选择和富集蛋白质
EP2210104A4 (en) * 2007-11-01 2011-02-23 Univ Arizona State CELL-FREE PROCEDURE FOR DETECTING PROTEIN-LIGAND INTERACTIONS
US8153446B2 (en) 2008-05-23 2012-04-10 Kent State University Fluorogenic compounds converted to fluorophores by photochemical or chemical means and their use in biological systems
US8871686B2 (en) * 2009-07-07 2014-10-28 Agency For Science, Technology And Research Methods of identifying a pair of binding partners
DK2622073T5 (da) * 2010-09-27 2019-02-25 Vipergen Fremgangsmåde til fremstilling af et beriget bibliotek

Also Published As

Publication number Publication date
US20170233726A1 (en) 2017-08-17
IL224694A0 (en) 2013-07-31
WO2012041633A1 (en) 2012-04-05
DK2622073T3 (da) 2018-07-30
EP2622073B1 (en) 2018-04-18
CN103119165A (zh) 2013-05-22
US10513700B2 (en) 2019-12-24
US20130288929A1 (en) 2013-10-31
JP2013540440A (ja) 2013-11-07
EP3399035A1 (en) 2018-11-07
JP6193761B2 (ja) 2017-09-06
CA2808656C (en) 2019-12-03
CA2808656A1 (en) 2012-04-05
DK2622073T5 (da) 2019-02-25
IL224694B (en) 2018-08-30
CN103119165B (zh) 2017-04-12
EP3399035B1 (en) 2021-02-17
EP2622073A1 (en) 2013-08-07
JP2017060513A (ja) 2017-03-30

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