DK2919777T3 - Transmukosal afgivelse af tocotrienol - Google Patents

Transmukosal afgivelse af tocotrienol Download PDF

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Publication number
DK2919777T3
DK2919777T3 DK13854440.8T DK13854440T DK2919777T3 DK 2919777 T3 DK2919777 T3 DK 2919777T3 DK 13854440 T DK13854440 T DK 13854440T DK 2919777 T3 DK2919777 T3 DK 2919777T3
Authority
DK
Denmark
Prior art keywords
transmukosal
tocotrienol
release
transmukosal release
Prior art date
Application number
DK13854440.8T
Other languages
English (en)
Inventor
Glenn Tong
Original Assignee
Invictus Biotechnology Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2012904937A external-priority patent/AU2012904937A0/en
Application filed by Invictus Biotechnology Pty Ltd filed Critical Invictus Biotechnology Pty Ltd
Application granted granted Critical
Publication of DK2919777T3 publication Critical patent/DK2919777T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355Tocopherols, e.g. vitamin E
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/006Oral mucosa, e.g. mucoadhesive forms, sublingual droplets; Buccal patches or films; Buccal sprays
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
DK13854440.8T 2012-11-13 2013-11-13 Transmukosal afgivelse af tocotrienol DK2919777T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2012904937A AU2012904937A0 (en) 2012-11-13 Sublingual and buccal delivery of tocotrienol derivatives as therapeutic agents
AU2012905406A AU2012905406A0 (en) 2012-12-11 Sublingual and buccal delivery of tocotrienol derivatives as therapeutic agents
PCT/AU2013/001310 WO2014075135A1 (en) 2012-11-13 2013-11-13 Transmucosal delivery of tocotrienol

Publications (1)

Publication Number Publication Date
DK2919777T3 true DK2919777T3 (da) 2020-03-09

Family

ID=50730398

Family Applications (1)

Application Number Title Priority Date Filing Date
DK13854440.8T DK2919777T3 (da) 2012-11-13 2013-11-13 Transmukosal afgivelse af tocotrienol

Country Status (23)

Country Link
US (2) US10675265B2 (da)
EP (1) EP2919777B1 (da)
JP (3) JP6460998B2 (da)
KR (1) KR20150082109A (da)
CN (2) CN104582700B (da)
AU (1) AU2013344817B2 (da)
BR (1) BR112015010703B1 (da)
CA (1) CA2891164C (da)
DK (1) DK2919777T3 (da)
ES (1) ES2778065T3 (da)
HK (1) HK1207295A1 (da)
IL (1) IL238727A0 (da)
IN (1) IN2015DN04006A (da)
MY (1) MY177940A (da)
NZ (1) NZ628963A (da)
PE (1) PE20151518A1 (da)
PH (1) PH12015501048A1 (da)
PL (1) PL2919777T3 (da)
PT (1) PT2919777T (da)
RU (1) RU2015120181A (da)
SG (1) SG11201503640WA (da)
WO (1) WO2014075135A1 (da)
ZA (1) ZA201504191B (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9171343B1 (en) 2012-09-11 2015-10-27 Aseko, Inc. Means and method for improved glycemic control for diabetic patients
US9897565B1 (en) 2012-09-11 2018-02-20 Aseko, Inc. System and method for optimizing insulin dosages for diabetic subjects
CN104582700B (zh) * 2012-11-13 2021-01-05 因维克特斯生物技术有限公司 生育三烯酚的经粘膜递送
US9486580B2 (en) 2014-01-31 2016-11-08 Aseko, Inc. Insulin management
US9233204B2 (en) 2014-01-31 2016-01-12 Aseko, Inc. Insulin management
EP3050023B1 (en) 2014-10-27 2021-08-25 Aseko, Inc. Subcutaneous outpatient management
US11081226B2 (en) 2014-10-27 2021-08-03 Aseko, Inc. Method and controller for administering recommended insulin dosages to a patient
US20170128412A1 (en) * 2015-08-11 2017-05-11 Satoru Sugiyama System and method for improved blood circulation and maintaining mitochondrial energy production
CA2993275C (en) 2015-08-20 2022-06-21 Aseko, Inc. Diabetes management therapy advisor
WO2019032685A1 (en) * 2017-08-08 2019-02-14 Robert John Petcavich FORMULATIONS FOR THE CONTRIBUTION OF TREHALOSE STIMULATING AUTOPHAGIA
CN117098556A (zh) * 2020-12-04 2023-11-21 因维克特斯生物技术有限公司 生育三烯酚的经粘膜递送

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EP0543417A1 (en) * 1991-11-22 1993-05-26 Lipogenics, Incorporated Tocotrienols and tocotrienol-like compounds and methods for their use
JPH0892050A (ja) 1994-09-27 1996-04-09 Lion Corp 消臭剤及び口腔用組成物
JP4271742B2 (ja) * 1997-08-07 2009-06-03 エーザイ・アール・アンド・ディー・マネジメント株式会社 免疫機能改善剤
US6264981B1 (en) 1999-10-27 2001-07-24 Anesta Corporation Oral transmucosal drug dosage using solid solution
ATE470442T1 (de) 2000-03-31 2010-06-15 Eisai R&D Man Co Ltd Verwendung von gamma-tocotrienol als diuretika
JP2001342133A (ja) * 2000-03-31 2001-12-11 Eisai Co Ltd γ―トコトリエノール含有利尿剤
JP2002037727A (ja) 2000-07-26 2002-02-06 Eisai Co Ltd 脂溶性薬物を配合した速崩性固形製剤及びその製造方法
JP4693140B2 (ja) 2000-10-06 2011-06-01 富士化学工業株式会社 トコトリエノール含有医薬用剤
US6608103B2 (en) * 2001-02-08 2003-08-19 Fuji Chemical Industry Co., Ltd. Inhibitor for neovasculation, cell multiplication, lumen formation and FGF
JP4447198B2 (ja) * 2001-02-08 2010-04-07 富士化学工業株式会社 トコトリエノールを有効成分とする血管新生阻害剤、細胞増殖阻害剤、管腔形成阻害剤及びfgf阻害剤並びに食品或いは食品添加物
US7919525B2 (en) 2003-02-14 2011-04-05 Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Radiation protection by gamma-tocotrienol
SG2010050664A (en) * 2003-04-10 2015-09-29 Barrie Tan Annatto extract compositions including tocotrienols and tocopherols and methods of use
US20050209315A1 (en) * 2004-03-20 2005-09-22 Papas Andreas M Bioavailable nutritional supplement and method of treatment of malabsorption
DE602005025339D1 (de) * 2004-05-26 2011-01-27 Kgk Synergize Inc Flavonoide und Tocotrienole enthaltende Zusammensetzungen und deren Verwendungen
CN1775289B (zh) 2004-11-15 2011-08-24 杭州赛诺菲民生健康药业有限公司 多维生素口腔崩解片制剂及其制备方法
JP5613657B2 (ja) 2008-03-28 2014-10-29 ヘイル バイオファーマ ベンチャーズ,エルエルシー ベンゾジアゼピン組成物の投与
WO2009126866A2 (en) * 2008-04-10 2009-10-15 Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. Delta-tocotrienol as a radioprotective countermeasure agent
JP2012527406A (ja) 2009-05-20 2012-11-08 リングアル コンセグナ ピーティーワイ エルティーディー 口腔内および/または舌下治療用製剤
JP2012531411A (ja) 2009-06-25 2012-12-10 アンペア ライフ サイエンシーズ,インコーポレイテッド トコトリエノールまたはトコトリエノール濃縮抽出物を用いた広汎性発達障害の処置
HUE037592T2 (hu) * 2009-08-26 2018-09-28 Bioelectron Tech Corp Eljárások cerebrális ischemia megelõzésére és kezelésére
WO2011082355A1 (en) * 2009-12-31 2011-07-07 Edison Pharmaceuticals, Inc. Treatment of leigh syndrome and leigh-like syndrome with tocotrienol quinones
BR112012025558A2 (pt) 2010-04-06 2016-06-28 Edison Pharmaceuticals Inc tratamento para a ataxia-telangiectasia
WO2012068552A1 (en) * 2010-11-19 2012-05-24 Edison Pharmaceuticals, Inc. Methods for improving blood glucose control
MX2018007514A (es) 2011-02-18 2022-10-21 Biolingus Ip Llc Proceso para preparar productos que comprenden activos estabilizados y composiciones que los comprenden.
CN107737100A (zh) 2011-06-14 2018-02-27 哈尔生物药投资有限责任公司 苯二氮卓组合物的投与
CN104582700B (zh) * 2012-11-13 2021-01-05 因维克特斯生物技术有限公司 生育三烯酚的经粘膜递送

Also Published As

Publication number Publication date
AU2013344817B2 (en) 2015-09-17
MY177940A (en) 2020-09-28
US20150265570A1 (en) 2015-09-24
KR20150082109A (ko) 2015-07-15
ES2778065T3 (es) 2020-08-07
ZA201504191B (en) 2016-11-30
HK1207295A1 (en) 2016-01-29
US20200246306A1 (en) 2020-08-06
JP2016503407A (ja) 2016-02-04
JP6978392B2 (ja) 2021-12-08
BR112015010703A2 (pt) 2017-07-11
PE20151518A1 (es) 2015-11-25
EP2919777B1 (en) 2020-01-08
PH12015501048A1 (en) 2015-07-27
AU2013344817A1 (en) 2015-02-12
EP2919777A1 (en) 2015-09-23
CN104582700B (zh) 2021-01-05
CN112451518A (zh) 2021-03-09
IL238727A0 (en) 2015-06-30
JP6460998B2 (ja) 2019-01-30
RU2015120181A (ru) 2017-01-10
US11331302B2 (en) 2022-05-17
CA2891164C (en) 2021-02-09
IN2015DN04006A (da) 2015-10-02
EP2919777A4 (en) 2016-05-18
BR112015010703B1 (pt) 2021-02-17
PT2919777T (pt) 2020-03-30
JP2019031504A (ja) 2019-02-28
WO2014075135A1 (en) 2014-05-22
NZ628963A (en) 2017-02-24
CA2891164A1 (en) 2014-05-22
JP2021008509A (ja) 2021-01-28
SG11201503640WA (en) 2015-06-29
US10675265B2 (en) 2020-06-09
PL2919777T3 (pl) 2020-07-13
CN104582700A (zh) 2015-04-29
BR112015010703A8 (pt) 2018-08-14

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