DK2699553T3 - Substituerede diaminocarboxamid- og diaminocarbonitrilpyrimidiner, sammensætninger deraf og fremgangsmåder til behandling dermed - Google Patents
Substituerede diaminocarboxamid- og diaminocarbonitrilpyrimidiner, sammensætninger deraf og fremgangsmåder til behandling dermed Download PDFInfo
- Publication number
- DK2699553T3 DK2699553T3 DK12718524.7T DK12718524T DK2699553T3 DK 2699553 T3 DK2699553 T3 DK 2699553T3 DK 12718524 T DK12718524 T DK 12718524T DK 2699553 T3 DK2699553 T3 DK 2699553T3
- Authority
- DK
- Denmark
- Prior art keywords
- compositions
- processes
- treatment
- diaminocarboxamide
- substituted
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- CTAWBMDQTAZKIE-UHFFFAOYSA-N n,n-diaminoformamide Chemical class NN(N)C=O CTAWBMDQTAZKIE-UHFFFAOYSA-N 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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US201161478076P | 2011-04-22 | 2011-04-22 | |
US201161555339P | 2011-11-03 | 2011-11-03 | |
PCT/US2012/034349 WO2012145569A1 (en) | 2011-04-22 | 2012-04-20 | Substituted diaminocarboxamide and diaminocarbonitrile pyrimidines, compositions thereof, and methods of treatment therewith |
Publications (1)
Publication Number | Publication Date |
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DK2699553T3 true DK2699553T3 (da) | 2024-01-29 |
Family
ID=46025954
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12718524.7T DK2699553T3 (da) | 2011-04-22 | 2012-04-20 | Substituerede diaminocarboxamid- og diaminocarbonitrilpyrimidiner, sammensætninger deraf og fremgangsmåder til behandling dermed |
Country Status (33)
Country | Link |
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US (7) | US9139534B2 (da) |
EP (2) | EP2699553B1 (da) |
JP (5) | JP6027095B2 (da) |
KR (2) | KR102055532B1 (da) |
CN (5) | CN105001165B (da) |
AR (1) | AR087151A1 (da) |
AU (1) | AU2012245387C1 (da) |
BR (1) | BR112013022813B1 (da) |
CA (1) | CA2829264C (da) |
CL (1) | CL2013003025A1 (da) |
CO (1) | CO6821941A2 (da) |
CR (1) | CR20130490A (da) |
DK (1) | DK2699553T3 (da) |
EC (1) | ECSP13012985A (da) |
FI (1) | FI2699553T3 (da) |
HR (1) | HRP20240097T1 (da) |
HU (1) | HUE064883T2 (da) |
IL (3) | IL228721A (da) |
LT (1) | LT2699553T (da) |
MX (1) | MX351754B (da) |
NI (1) | NI201300113A (da) |
PE (1) | PE20140502A1 (da) |
PH (1) | PH12015501677A1 (da) |
PL (1) | PL2699553T3 (da) |
PT (1) | PT2699553T (da) |
RS (1) | RS65202B1 (da) |
RU (2) | RU2697712C2 (da) |
SG (2) | SG10201702654VA (da) |
SI (1) | SI2699553T1 (da) |
TW (3) | TWI681952B (da) |
UA (1) | UA120740C2 (da) |
WO (1) | WO2012145569A1 (da) |
ZA (1) | ZA201306471B (da) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2697712C2 (ru) | 2011-04-22 | 2019-08-19 | СИГНАЛ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи | Замещенные диаминокарбоксамидные и диаминокарбонитрильные производные пиримидинов, их композиции и способы лечения с их помощью |
CN104903301B (zh) * | 2012-11-08 | 2017-08-29 | 百时美施贵宝公司 | 可用于调节IL‑12、IL‑23和/或IFNα的烷基酰胺取代的嘧啶化合物 |
CA2903431C (en) | 2013-03-14 | 2022-12-06 | Kalyra Pharmaceuticals, Inc. | Bicyclopentane analgesic compounds |
WO2015039613A1 (zh) * | 2013-09-18 | 2015-03-26 | 北京韩美药品有限公司 | 抑制btk和/或jak3激酶活性的化合物 |
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