DK1631569T3 - Quinuclidinderivater, der binder til muscariniske M3-receptorer - Google Patents

Quinuclidinderivater, der binder til muscariniske M3-receptorer

Info

Publication number: DK1631569T3
Authority: DK; Denmark
Prior art keywords: muscarinic; receptors; bind; quinuclidine derivatives; quinuclidine
Prior art date: 2003-05-02

Application number

DK04730519T

Other languages

Danish (da)

English (en)

Inventor

Stephen Paul Collingwood

Brian Cox

Urs Baettig

Gurdip Bhalay

Nicholas James Devereux

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-05-02

Filing date

2004-04-30

Publication date

2009-11-23

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33420896&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1631569(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2003-10-24 Priority claimed from GB0324887A external-priority patent/GB0324887D0/en

2004-04-30 Application filed by Novartis Ag filed Critical Novartis Ag

2009-11-23 Application granted granted Critical

2009-11-23 Publication of DK1631569T3 publication Critical patent/DK1631569T3/da

Links

102000007202 Muscarinic M3 Receptor Human genes 0.000 title 1
108010008405 Muscarinic M3 Receptor Proteins 0.000 title 1
150000008584 quinuclidines Chemical class 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

DK04730519T 2003-05-02 2004-04-30 Quinuclidinderivater, der binder til muscariniske M3-receptorer DK1631569T3 (da)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0310232		2003-05-02
GB0324887A GB0324887D0 (en)	2003-10-24	2003-10-24	Organic compounds
PCT/EP2004/004605 WO2004096800A2 (en)	2003-05-02	2004-04-30	Quinuclidine derivatives binding to mucarinic m3 receptors

Publications (1)

Publication Number	Publication Date
DK1631569T3 true DK1631569T3 (da)	2009-11-23

Family

ID=33420896

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK04730519T DK1631569T3 (da)	2003-05-02	2004-04-30	Quinuclidinderivater, der binder til muscariniske M3-receptorer

Country Status (32)

Country	Link
US (2)	US20070060563A1 (es)
EP (1)	EP1631569B1 (es)
JP (1)	JP4416786B2 (es)
KR (1)	KR100896544B1 (es)
AR (1)	AR044134A1 (es)
AT (1)	ATE440840T1 (es)
AU (1)	AU2004234069B2 (es)
BR (1)	BRPI0410238A (es)
CA (1)	CA2523436C (es)
CL (1)	CL2004000918A1 (es)
CO (1)	CO5700782A2 (es)
CY (1)	CY1109655T1 (es)
DE (1)	DE602004022805D1 (es)
DK (1)	DK1631569T3 (es)
EC (1)	ECSP056134A (es)
ES (1)	ES2331185T3 (es)
HK (1)	HK1087704A1 (es)
HR (1)	HRP20050933A2 (es)
IL (1)	IL171591A (es)
IS (1)	IS2746B (es)
MA (1)	MA27775A1 (es)
MX (1)	MXPA05011739A (es)
MY (1)	MY142652A (es)
NO (1)	NO20055688L (es)
NZ (1)	NZ542995A (es)
PE (1)	PE20050465A1 (es)
PL (1)	PL1631569T3 (es)
PT (1)	PT1631569E (es)
RU (1)	RU2363700C2 (es)
SI (1)	SI1631569T1 (es)
TW (1)	TWI340139B (es)
WO (1)	WO2004096800A2 (es)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2239546B1 (es) *	2004-03-15	2006-12-01	Almirall Prodesfarma, S.A.	Nuevos esteres de quinuclidina cuaternizados.
GB0410712D0 (en)	2004-05-13	2004-06-16	Novartis Ag	Organic compounds
GB0424284D0 (en)	2004-11-02	2004-12-01	Novartis Ag	Organic compounds
GB0428416D0 (en)	2004-12-24	2005-02-02	Novartis Ag	Organic compounds
GB0601951D0 (en)	2006-01-31	2006-03-15	Novartis Ag	Organic compounds
EP1900737A1 (en) *	2006-08-31	2008-03-19	Novartis AG	Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide
EP1894568A1 (en) *	2006-08-31	2008-03-05	Novartis AG	Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
TW200825084A (en)	2006-11-14	2008-06-16	Astrazeneca Ab	New compounds 521
ATE555111T1 (de) *	2006-12-19	2012-05-15	Astrazeneca Ab	Chinuclidinol-derivate als muscarinrezeptor- antagonisten
EP1950196A1 (de) *	2007-01-29	2008-07-30	Boehringer Ingelheim Pharma GmbH & Co. KG	Verfahren zur Herstellung von Ammoniumhexafluorophosphaten
PL2197841T3 (pl)	2007-09-07	2012-04-30	Theravance Inc	Związki zawierające guanidynę przydatne jako antagoniści receptorów
EP2222637A1 (en)	2007-12-14	2010-09-01	Theravance, Inc.	Amidine-containing compounds useful as muscarinic receptor antagonists
PL2231642T3 (pl)	2008-01-11	2014-04-30	Novartis Ag	Pirymidyny jako inhibitory kinazy
EP2300464A1 (en)	2008-05-13	2011-03-30	AstraZeneca AB	Quinuclidine derivatives as muscarinic m3 receptor antagonists
CN102088976B (zh) *	2008-05-13	2012-12-26	阿斯利康(瑞典)有限公司	包含毒蕈碱性受体拮抗剂和β2-肾上腺素受体激动剂的药物产品
GB0808709D0 (en) *	2008-05-13	2008-06-18	Astrazeneca Ab	New combination 295
US20090326004A1 (en)	2008-06-03	2009-12-31	Ranbaxy Laboratories Limited	Muscarinic receptor antagonists
WO2009153536A1 (en) *	2008-06-17	2009-12-23	Argenta Discovery Limited	1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
GB0811100D0 (en) *	2008-06-17	2008-07-23	Astrazeneca Ab	New combination
RU2580835C2 (ru) *	2010-06-22	2016-04-10	КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А.	Алкалоидные производные на основе сложных аминоэфиров и композиции лекарственных средств, содержащие их
US8637516B2 (en)	2010-09-09	2014-01-28	Irm Llc	Compounds and compositions as TRK inhibitors
WO2012034095A1 (en)	2010-09-09	2012-03-15	Irm Llc	Compounds and compositions as trk inhibitors
CA2828219A1 (en)	2011-02-25	2012-08-30	Irm Llc	Pyrazolo [1,5-a] pyridines as trk inhibitors
JP2011195593A (ja) *	2011-06-30	2011-10-06	Astrazeneca Ab	ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
CA2862008A1 (en) *	2011-12-30	2013-07-04	Chiesi Farmaceutici S.P.A.	Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof
EP2844251B1 (en) *	2012-05-03	2018-08-01	Saint Louis College of Pharmacy	Compositions and methods for increasing neurotrophic peptides
TWI647227B (zh) *	2013-02-28	2019-01-11	日商安斯泰來製藥股份有限公司	２－醯胺噻唑衍生物或其鹽
CZ306791B6 (cs)	2013-10-29	2017-07-12	Zentiva, K.S.	Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě
PT108370B (pt) *	2015-03-30	2018-10-25	Hovione Farm S A	Processo de preparação de brometo de aclidínio
EP3111978B1 (en)	2015-07-03	2021-09-01	Novartis AG	Inhaler adapted to read information stored in a data storage means of a container

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1219606A (en) *	1968-07-15	1971-01-20	Rech S Et D Applic Scient Soge	Quinuclidinol derivatives and preparation thereof
DK534178A (da) *	1977-12-16	1979-06-17	Interx Research Corp	Anticholinerge midler med sektrtionshaemmende virkning
ES2165768B1 (es) *	1999-07-14	2003-04-01	Almirall Prodesfarma Sa	Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
WO2002004402A1 (fr) *	2000-07-11	2002-01-17	Banyu Pharmaceutical Co., Ltd.	Derives d'ester
CN1250545C (zh) *	2000-12-28	2006-04-12	阿尔米雷尔普罗迪斯制药有限公司	新的奎宁环衍生物类及含有这类衍生物的药物组合物
IL162596A0 (en) *	2001-12-20	2005-11-20	S A L V A T Lab Sa	1-Alkyl-1-azoniabicyclo Ä2.2.2Ü octane carbamate derivatives and their use as muscarinic receptor ntagonists
GB0424284D0 (en) *	2004-11-02	2004-12-01	Novartis Ag	Organic compounds
EP1900737A1 (en) *	2006-08-31	2008-03-19	Novartis AG	Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide

2004
- 2004-04-29 AR ARP040101468A patent/AR044134A1/es not_active Application Discontinuation
- 2004-04-30 US US10/554,558 patent/US20070060563A1/en not_active Abandoned
- 2004-04-30 ES ES04730519T patent/ES2331185T3/es not_active Expired - Lifetime
- 2004-04-30 DE DE602004022805T patent/DE602004022805D1/de not_active Expired - Lifetime
- 2004-04-30 RU RU2005137360/04A patent/RU2363700C2/ru not_active IP Right Cessation
- 2004-04-30 TW TW093112339A patent/TWI340139B/zh not_active IP Right Cessation
- 2004-04-30 PE PE2004000435A patent/PE20050465A1/es not_active Application Discontinuation
- 2004-04-30 CA CA2523436A patent/CA2523436C/en not_active Expired - Fee Related
- 2004-04-30 CL CL200400918A patent/CL2004000918A1/es unknown
- 2004-04-30 NZ NZ542995A patent/NZ542995A/en not_active IP Right Cessation
- 2004-04-30 WO PCT/EP2004/004605 patent/WO2004096800A2/en active Application Filing
- 2004-04-30 SI SI200431277T patent/SI1631569T1/sl unknown
- 2004-04-30 JP JP2006505341A patent/JP4416786B2/ja not_active Expired - Fee Related
- 2004-04-30 BR BRPI0410238-0A patent/BRPI0410238A/pt not_active IP Right Cessation
- 2004-04-30 MX MXPA05011739A patent/MXPA05011739A/es active IP Right Grant
- 2004-04-30 AT AT04730519T patent/ATE440840T1/de active
- 2004-04-30 EP EP04730519A patent/EP1631569B1/en not_active Expired - Lifetime
- 2004-04-30 MY MYPI20041637A patent/MY142652A/en unknown
- 2004-04-30 AU AU2004234069A patent/AU2004234069B2/en not_active Ceased
- 2004-04-30 KR KR1020057020776A patent/KR100896544B1/ko not_active IP Right Cessation
- 2004-04-30 PT PT04730519T patent/PT1631569E/pt unknown
- 2004-04-30 DK DK04730519T patent/DK1631569T3/da active
- 2004-04-30 PL PL04730519T patent/PL1631569T3/pl unknown
2005
- 2005-10-27 IL IL171591A patent/IL171591A/en not_active IP Right Cessation
- 2005-10-28 HR HR20050933A patent/HRP20050933A2/xx not_active Application Discontinuation
- 2005-11-01 EC EC2005006134A patent/ECSP056134A/es unknown
- 2005-11-03 CO CO05112195A patent/CO5700782A2/es not_active Application Discontinuation
- 2005-11-08 MA MA28583A patent/MA27775A1/fr unknown
- 2005-11-30 IS IS8158A patent/IS2746B/is unknown
- 2005-12-01 NO NO20055688A patent/NO20055688L/no not_active Application Discontinuation
2006
- 2006-07-17 HK HK06107974.9A patent/HK1087704A1/xx not_active IP Right Cessation
2009
- 2009-10-20 US US12/582,291 patent/US8168654B2/en not_active Expired - Fee Related
- 2009-11-25 CY CY20091101230T patent/CY1109655T1/el unknown

Also Published As

Publication number	Publication date
US8168654B2 (en)	2012-05-01
EP1631569B1 (en)	2009-08-26
CY1109655T1 (el)	2014-08-13
MA27775A1 (fr)	2006-02-01
PT1631569E (pt)	2009-11-26
BRPI0410238A (pt)	2006-05-16
AU2004234069A1 (en)	2004-11-11
HK1087704A1 (en)	2006-10-20
CO5700782A2 (es)	2006-11-30
HRP20050933A2 (en)	2006-12-31
PE20050465A1 (es)	2005-07-18
IS8158A (is)	2005-11-30
ES2331185T3 (es)	2009-12-23
KR100896544B1 (ko)	2009-05-07
CA2523436A1 (en)	2004-11-11
RU2363700C2 (ru)	2009-08-10
IS2746B (is)	2011-08-15
ATE440840T1 (de)	2009-09-15
MXPA05011739A (es)	2006-01-26
CA2523436C (en)	2011-11-01
CL2004000918A1 (es)	2005-02-11
NO20055688L (no)	2006-01-09
WO2004096800A2 (en)	2004-11-11
KR20060015572A (ko)	2006-02-17
US20070060563A1 (en)	2007-03-15
JP4416786B2 (ja)	2010-02-17
AR044134A1 (es)	2005-08-24
ECSP056134A (es)	2006-04-19
NZ542995A (en)	2009-02-28
TWI340139B (en)	2011-04-11
TW200505920A (en)	2005-02-16
PL1631569T3 (pl)	2010-02-26
SI1631569T1 (sl)	2010-01-29
AU2004234069B2 (en)	2008-02-21
EP1631569A2 (en)	2006-03-08
JP2006525267A (ja)	2006-11-09
DE602004022805D1 (de)	2009-10-08
MY142652A (en)	2010-12-15
NO20055688D0 (no)	2005-12-01
RU2005137360A (ru)	2006-07-27
WO2004096800A3 (en)	2005-01-06
US20100041887A1 (en)	2010-02-18
IL171591A (en)	2010-11-30

Publication	Publication Date	Title
DK1631569T3 (da)	2009-11-23	Quinuclidinderivater, der binder til muscariniske M3-receptorer
DK1730191T3 (da)	2011-10-17	Immunglobulin som binder HOSM
LTC1725537I2 (lt)	2018-02-26	Nauji junginiai, kaip opioido receptoriaus moduliatoriai
DK1572874T3 (da)	2013-12-16	Antistoffer, der immunospecifikt binder til TRAIL receptorer
ATE380166T1 (de)	2007-12-15	Hydraulisches bindemittel
NO20055847D0 (no)	2005-12-09	Nye peptider som binder til erytiupoietinreseptoren
DK1629007T3 (da)	2009-06-29	Hidtil ukendte peptider som binder til erythropoietin-receptoren
IS3021B (is)	2020-04-15	Mótefni gegn M-CSF
DE602005027445D1 (de)	2011-05-26	Neue zusammensetzungen mit chinolin-verbindungen
DK2177537T3 (da)	2011-12-12	Antistoffer til MAdCAM
DK2215119T3 (da)	2013-02-04	Monoklonale antistoffer der binder til HGM-CSF og medicinske sammensætninger omfattende de samme.
DE602006008032D1 (de)	2009-09-03	Asphaltbindemittel für poröse pflaster
DK1963369T3 (da)	2013-06-03	Il-21-antagonister
ATE387202T1 (de)	2008-03-15	Pyrrolidinderivate als histaminrezeptor-liganden
DK1957517T3 (da)	2013-04-08	Anvendelse af peptider, der binder til TPO-receptor
JP2008525358A5 (ja)	2009-02-12	Ｍ３ムスカリン受容体としてのピロリジニウム誘導体
ZA200608273B (en)	2007-06-27	Hydraulic binder
ATE404546T1 (de)	2008-08-15	Substituierte n-sulfonylaminobenzyl-2- phenoxyacetamidverbindungen
DK1812448T3 (da)	2012-08-27	Organiske forbindelser
DK1539739T3 (da)	2011-03-07	Piperidinylforbindelser, der selektivt binder integriner
DK1725223T3 (da)	2011-11-28	Anvendelse af antagonister til CB1-receptoren til fremstilling af en sammensætning, der er anvendelig til behandling af leversygdomme
MA28801B1 (fr)	2007-08-01	Composition antihistaminique
DK200700967A (da)	2007-07-02	Omledningsværktöj
DE602005008596D1 (de)	2008-09-11	Neue tetracyclische tetrahydrofuranderivate
DK1871804T3 (da)	2013-12-02	Antistoffer, der binder CCX-CKR2