HK1087704A1 - Quinuclidine derivatives binding to mucarinic m3 receptors - Google Patents

Quinuclidine derivatives binding to mucarinic m3 receptors

Info

Publication number
HK1087704A1
HK1087704A1 HK06107974.9A HK06107974A HK1087704A1 HK 1087704 A1 HK1087704 A1 HK 1087704A1 HK 06107974 A HK06107974 A HK 06107974A HK 1087704 A1 HK1087704 A1 HK 1087704A1
Authority
HK
Hong Kong
Prior art keywords
mucarinic
receptors
quinuclidine derivatives
derivatives binding
binding
Prior art date
Application number
HK06107974.9A
Other languages
English (en)
Inventor
Stephen Paul Collingwood
Brian Cox
Urs Baettig
Gurdip Bhalay
Nicholas James Devereux
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33420896&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1087704(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0324887A external-priority patent/GB0324887D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HK1087704A1 publication Critical patent/HK1087704A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK06107974.9A 2003-05-02 2006-07-17 Quinuclidine derivatives binding to mucarinic m3 receptors HK1087704A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0310232 2003-05-02
GB0324887A GB0324887D0 (en) 2003-10-24 2003-10-24 Organic compounds
PCT/EP2004/004605 WO2004096800A2 (en) 2003-05-02 2004-04-30 Quinuclidine derivatives binding to mucarinic m3 receptors

Publications (1)

Publication Number Publication Date
HK1087704A1 true HK1087704A1 (en) 2006-10-20

Family

ID=33420896

Family Applications (1)

Application Number Title Priority Date Filing Date
HK06107974.9A HK1087704A1 (en) 2003-05-02 2006-07-17 Quinuclidine derivatives binding to mucarinic m3 receptors

Country Status (32)

Country Link
US (2) US20070060563A1 (xx)
EP (1) EP1631569B1 (xx)
JP (1) JP4416786B2 (xx)
KR (1) KR100896544B1 (xx)
AR (1) AR044134A1 (xx)
AT (1) ATE440840T1 (xx)
AU (1) AU2004234069B2 (xx)
BR (1) BRPI0410238A (xx)
CA (1) CA2523436C (xx)
CL (1) CL2004000918A1 (xx)
CO (1) CO5700782A2 (xx)
CY (1) CY1109655T1 (xx)
DE (1) DE602004022805D1 (xx)
DK (1) DK1631569T3 (xx)
EC (1) ECSP056134A (xx)
ES (1) ES2331185T3 (xx)
HK (1) HK1087704A1 (xx)
HR (1) HRP20050933A2 (xx)
IL (1) IL171591A (xx)
IS (1) IS2746B (xx)
MA (1) MA27775A1 (xx)
MX (1) MXPA05011739A (xx)
MY (1) MY142652A (xx)
NO (1) NO20055688L (xx)
NZ (1) NZ542995A (xx)
PE (1) PE20050465A1 (xx)
PL (1) PL1631569T3 (xx)
PT (1) PT1631569E (xx)
RU (1) RU2363700C2 (xx)
SI (1) SI1631569T1 (xx)
TW (1) TWI340139B (xx)
WO (1) WO2004096800A2 (xx)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2239546B1 (es) * 2004-03-15 2006-12-01 Almirall Prodesfarma, S.A. Nuevos esteres de quinuclidina cuaternizados.
GB0410712D0 (en) 2004-05-13 2004-06-16 Novartis Ag Organic compounds
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0428416D0 (en) 2004-12-24 2005-02-02 Novartis Ag Organic compounds
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide
EP1894568A1 (en) * 2006-08-31 2008-03-05 Novartis AG Pharmaceutical compositions for the treatment of inflammatory or obstructive airway diseases
TW200825084A (en) 2006-11-14 2008-06-16 Astrazeneca Ab New compounds 521
ATE555111T1 (de) * 2006-12-19 2012-05-15 Astrazeneca Ab Chinuclidinol-derivate als muscarinrezeptor- antagonisten
EP1950196A1 (de) * 2007-01-29 2008-07-30 Boehringer Ingelheim Pharma GmbH & Co. KG Verfahren zur Herstellung von Ammoniumhexafluorophosphaten
CA2697752C (en) 2007-09-07 2016-01-26 Theravance, Inc. Guanidine-containing compounds useful as muscarinic receptor antagonists
EP2222637A1 (en) 2007-12-14 2010-09-01 Theravance, Inc. Amidine-containing compounds useful as muscarinic receptor antagonists
ES2442930T3 (es) 2008-01-11 2014-02-14 Novartis Ag Pirimidinas como inhibidores de cinasas
CN102089304A (zh) 2008-05-13 2011-06-08 阿斯利康(瑞典)有限公司 作为m3毒蕈碱性受体拮抗剂的奎宁环衍生物
GB0808709D0 (en) * 2008-05-13 2008-06-18 Astrazeneca Ab New combination 295
EP2315589A4 (en) * 2008-05-13 2013-09-11 Astrazeneca Ab PHARMACEUTICAL PRODUCT COMPRISING A MUSCARINIC RECEPTOR ANTAGONIST AND A beta2-ADRENOCEPTOR AGONIST
US20090326004A1 (en) 2008-06-03 2009-12-31 Ranbaxy Laboratories Limited Muscarinic receptor antagonists
GB0811100D0 (en) * 2008-06-17 2008-07-23 Astrazeneca Ab New combination
WO2009153536A1 (en) * 2008-06-17 2009-12-23 Argenta Discovery Limited 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists
WO2011161018A1 (en) * 2010-06-22 2011-12-29 Chiesi Farmaceutici S.P.A. Alkaloid aminoester derivatives and medicinal compositions thereof
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
CA2828219A1 (en) 2011-02-25 2012-08-30 Irm Llc Pyrazolo [1,5-a] pyridines as trk inhibitors
JP2011195593A (ja) * 2011-06-30 2011-10-06 Astrazeneca Ab ムスカリンｍ３受容体アンタゴニストとしてのキヌクリジン誘導体
RU2628082C2 (ru) * 2011-12-30 2017-08-14 КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. Хинуклидиновые эфиры 1-азагетероциклилуксусной кислоты в качестве антимускариновых средств, способ их получения и их лекарственные композиции
EP2844251B1 (en) 2012-05-03 2018-08-01 Saint Louis College of Pharmacy Compositions and methods for increasing neurotrophic peptides
TWI647227B (zh) * 2013-02-28 2019-01-11 日商安斯泰來製藥股份有限公司 ２－醯胺噻唑衍生物或其鹽
CZ306791B6 (cs) 2013-10-29 2017-07-12 Zentiva, K.S. Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě
PT108370B (pt) * 2015-03-30 2018-10-25 Hovione Farm S A Processo de preparação de brometo de aclidínio
PL3111978T3 (pl) 2015-07-03 2022-01-24 Novartis Ag Inhalator przystosowany do odczytu informacji przechowywanych w środkach przechowywania danych pojemnika

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1219606A (en) * 1968-07-15 1971-01-20 Rech S Et D Applic Scient Soge Quinuclidinol derivatives and preparation thereof
DK534178A (da) * 1977-12-16 1979-06-17 Interx Research Corp Anticholinerge midler med sektrtionshaemmende virkning
ES2165768B1 (es) * 1999-07-14 2003-04-01 Almirall Prodesfarma Sa Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
EP1302458A4 (en) * 2000-07-11 2005-10-19 Banyu Pharma Co Ltd ESTERDERIVATE
RU2282629C2 (ru) * 2000-12-28 2006-08-27 Альмиралль Продесфарма Аг Производные хинуклидина, способ их получения и фармацевтическая композиция на их основе
EA006505B1 (ru) * 2001-12-20 2005-12-29 Лабораториос С.А.Л.В.А.Т.,С.А. Производные карбамата 1-алкил-1-азониабицикло[2.2.2]октана и их применение в качестве антагонистов мускаринового рецептора
GB0424284D0 (en) * 2004-11-02 2004-12-01 Novartis Ag Organic compounds
EP1900737A1 (en) * 2006-08-31 2008-03-19 Novartis AG Polymorph of (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromide

Also Published As

Publication number Publication date
CA2523436A1 (en) 2004-11-11
CO5700782A2 (es) 2006-11-30
ES2331185T3 (es) 2009-12-23
DE602004022805D1 (de) 2009-10-08
KR20060015572A (ko) 2006-02-17
MA27775A1 (fr) 2006-02-01
US20070060563A1 (en) 2007-03-15
JP4416786B2 (ja) 2010-02-17
DK1631569T3 (da) 2009-11-23
IS2746B (is) 2011-08-15
AU2004234069B2 (en) 2008-02-21
KR100896544B1 (ko) 2009-05-07
RU2363700C2 (ru) 2009-08-10
NO20055688L (no) 2006-01-09
EP1631569A2 (en) 2006-03-08
IS8158A (is) 2005-11-30
PE20050465A1 (es) 2005-07-18
US8168654B2 (en) 2012-05-01
BRPI0410238A (pt) 2006-05-16
WO2004096800A2 (en) 2004-11-11
AR044134A1 (es) 2005-08-24
PT1631569E (pt) 2009-11-26
HRP20050933A2 (en) 2006-12-31
TWI340139B (en) 2011-04-11
NO20055688D0 (no) 2005-12-01
SI1631569T1 (sl) 2010-01-29
ATE440840T1 (de) 2009-09-15
TW200505920A (en) 2005-02-16
PL1631569T3 (pl) 2010-02-26
EP1631569B1 (en) 2009-08-26
ECSP056134A (es) 2006-04-19
CA2523436C (en) 2011-11-01
AU2004234069A1 (en) 2004-11-11
CY1109655T1 (el) 2014-08-13
CL2004000918A1 (es) 2005-02-11
RU2005137360A (ru) 2006-07-27
MY142652A (en) 2010-12-15
JP2006525267A (ja) 2006-11-09
WO2004096800A3 (en) 2005-01-06
IL171591A (en) 2010-11-30
US20100041887A1 (en) 2010-02-18
MXPA05011739A (es) 2006-01-26
NZ542995A (en) 2009-02-28

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20130430