DE602004022805D1 - Quinuclidin-derivate bindend an muscarin-m3-rezeptoren - Google Patents
Quinuclidin-derivate bindend an muscarin-m3-rezeptorenInfo
- Publication number
- DE602004022805D1 DE602004022805D1 DE602004022805T DE602004022805T DE602004022805D1 DE 602004022805 D1 DE602004022805 D1 DE 602004022805D1 DE 602004022805 T DE602004022805 T DE 602004022805T DE 602004022805 T DE602004022805 T DE 602004022805T DE 602004022805 D1 DE602004022805 D1 DE 602004022805D1
- Authority
- DE
- Germany
- Prior art keywords
- muscarin
- receptors
- derivatives binding
- quinuclidin derivatives
- quinuclidin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- UQOFGTXDASPNLL-XHNCKOQMSA-N Muscarine Chemical compound C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O UQOFGTXDASPNLL-XHNCKOQMSA-N 0.000 title 1
- SBYHFKPVCBCYGV-UHFFFAOYSA-N quinuclidine Chemical class C1CC2CCN1CC2 SBYHFKPVCBCYGV-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0310232 | 2003-05-02 | ||
GB0324887A GB0324887D0 (en) | 2003-10-24 | 2003-10-24 | Organic compounds |
PCT/EP2004/004605 WO2004096800A2 (en) | 2003-05-02 | 2004-04-30 | Quinuclidine derivatives binding to mucarinic m3 receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
DE602004022805D1 true DE602004022805D1 (de) | 2009-10-08 |
Family
ID=33420896
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004022805T Expired - Lifetime DE602004022805D1 (de) | 2003-05-02 | 2004-04-30 | Quinuclidin-derivate bindend an muscarin-m3-rezeptoren |
Country Status (32)
Country | Link |
---|---|
US (2) | US20070060563A1 (de) |
EP (1) | EP1631569B1 (de) |
JP (1) | JP4416786B2 (de) |
KR (1) | KR100896544B1 (de) |
AR (1) | AR044134A1 (de) |
AT (1) | ATE440840T1 (de) |
AU (1) | AU2004234069B2 (de) |
BR (1) | BRPI0410238A (de) |
CA (1) | CA2523436C (de) |
CL (1) | CL2004000918A1 (de) |
CO (1) | CO5700782A2 (de) |
CY (1) | CY1109655T1 (de) |
DE (1) | DE602004022805D1 (de) |
DK (1) | DK1631569T3 (de) |
EC (1) | ECSP056134A (de) |
ES (1) | ES2331185T3 (de) |
HK (1) | HK1087704A1 (de) |
HR (1) | HRP20050933A2 (de) |
IL (1) | IL171591A (de) |
IS (1) | IS2746B (de) |
MA (1) | MA27775A1 (de) |
MX (1) | MXPA05011739A (de) |
MY (1) | MY142652A (de) |
NO (1) | NO20055688L (de) |
NZ (1) | NZ542995A (de) |
PE (1) | PE20050465A1 (de) |
PL (1) | PL1631569T3 (de) |
PT (1) | PT1631569E (de) |
RU (1) | RU2363700C2 (de) |
SI (1) | SI1631569T1 (de) |
TW (1) | TWI340139B (de) |
WO (1) | WO2004096800A2 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2239546B1 (es) * | 2004-03-15 | 2006-12-01 | Almirall Prodesfarma, S.A. | Nuevos esteres de quinuclidina cuaternizados. |
GB0410712D0 (en) | 2004-05-13 | 2004-06-16 | Novartis Ag | Organic compounds |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0428416D0 (en) | 2004-12-24 | 2005-02-02 | Novartis Ag | Organic compounds |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
EP1900737A1 (de) * | 2006-08-31 | 2008-03-19 | Novartis AG | Polymorph von (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromid |
EP1894568A1 (de) * | 2006-08-31 | 2008-03-05 | Novartis AG | Pharmazeutische Zusammensetzungen zur Behandlung von entzündlichen oder obstruktiven Atemwegserkrankungen |
TW200825084A (en) | 2006-11-14 | 2008-06-16 | Astrazeneca Ab | New compounds 521 |
ATE555111T1 (de) * | 2006-12-19 | 2012-05-15 | Astrazeneca Ab | Chinuclidinol-derivate als muscarinrezeptor- antagonisten |
EP1950196A1 (de) * | 2007-01-29 | 2008-07-30 | Boehringer Ingelheim Pharma GmbH & Co. KG | Verfahren zur Herstellung von Ammoniumhexafluorophosphaten |
PL2197841T3 (pl) | 2007-09-07 | 2012-04-30 | Theravance Inc | Związki zawierające guanidynę przydatne jako antagoniści receptorów |
EP2222637A1 (de) | 2007-12-14 | 2010-09-01 | Theravance, Inc. | Amidinhaltige verbindungen als muscarinrezeptor-antagonisten |
PL2231642T3 (pl) | 2008-01-11 | 2014-04-30 | Novartis Ag | Pirymidyny jako inhibitory kinazy |
EP2300464A1 (de) | 2008-05-13 | 2011-03-30 | AstraZeneca AB | Chinuklidinderivate als antagonisten des muskarin-m3-rezeptors |
CN102088976B (zh) * | 2008-05-13 | 2012-12-26 | 阿斯利康(瑞典)有限公司 | 包含毒蕈碱性受体拮抗剂和β2-肾上腺素受体激动剂的药物产品 |
GB0808709D0 (en) * | 2008-05-13 | 2008-06-18 | Astrazeneca Ab | New combination 295 |
US20090326004A1 (en) | 2008-06-03 | 2009-12-31 | Ranbaxy Laboratories Limited | Muscarinic receptor antagonists |
WO2009153536A1 (en) * | 2008-06-17 | 2009-12-23 | Argenta Discovery Limited | 1-aza-bicyclo [2.2.2] octane derivatives useful as muscarinic receptor antagonists |
GB0811100D0 (en) * | 2008-06-17 | 2008-07-23 | Astrazeneca Ab | New combination |
RU2580835C2 (ru) * | 2010-06-22 | 2016-04-10 | КЬЕЗИ ФАРМАЧЕУТИЧИ С.п.А. | Алкалоидные производные на основе сложных аминоэфиров и композиции лекарственных средств, содержащие их |
US8637516B2 (en) | 2010-09-09 | 2014-01-28 | Irm Llc | Compounds and compositions as TRK inhibitors |
WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
CA2828219A1 (en) | 2011-02-25 | 2012-08-30 | Irm Llc | Pyrazolo [1,5-a] pyridines as trk inhibitors |
JP2011195593A (ja) * | 2011-06-30 | 2011-10-06 | Astrazeneca Ab | ムスカリンm3受容体アンタゴニストとしてのキヌクリジン誘導体 |
CA2862008A1 (en) * | 2011-12-30 | 2013-07-04 | Chiesi Farmaceutici S.P.A. | Quinuclidine esters of 1-azaheterocyclylacetic acid as antimuscarinic agents, process for their preparation and medicinal compositions thereof |
EP2844251B1 (de) * | 2012-05-03 | 2018-08-01 | Saint Louis College of Pharmacy | Zusammensetzungen und verfahren zur erhöhung neurotropher peptide |
TWI647227B (zh) * | 2013-02-28 | 2019-01-11 | 日商安斯泰來製藥股份有限公司 | 2-醯胺噻唑衍生物或其鹽 |
CZ306791B6 (cs) | 2013-10-29 | 2017-07-12 | Zentiva, K.S. | Průmyslově využitelný způsob přípravy aklidinium bromidu o vysoké čistotě |
PT108370B (pt) * | 2015-03-30 | 2018-10-25 | Hovione Farm S A | Processo de preparação de brometo de aclidínio |
EP3111978B1 (de) | 2015-07-03 | 2021-09-01 | Novartis AG | Zum lesen von in einem datenspeichermittel eines behälters gespeicherten informationen angepasster inhalator |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1219606A (en) * | 1968-07-15 | 1971-01-20 | Rech S Et D Applic Scient Soge | Quinuclidinol derivatives and preparation thereof |
DK534178A (da) * | 1977-12-16 | 1979-06-17 | Interx Research Corp | Anticholinerge midler med sektrtionshaemmende virkning |
ES2165768B1 (es) * | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
WO2002004402A1 (fr) * | 2000-07-11 | 2002-01-17 | Banyu Pharmaceutical Co., Ltd. | Derives d'ester |
CN1250545C (zh) * | 2000-12-28 | 2006-04-12 | 阿尔米雷尔普罗迪斯制药有限公司 | 新的奎宁环衍生物类及含有这类衍生物的药物组合物 |
IL162596A0 (en) * | 2001-12-20 | 2005-11-20 | S A L V A T Lab Sa | 1-Alkyl-1-azoniabicyclo Ä2.2.2Ü octane carbamate derivatives and their use as muscarinic receptor ntagonists |
GB0424284D0 (en) * | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
EP1900737A1 (de) * | 2006-08-31 | 2008-03-19 | Novartis AG | Polymorph von (R)-3-(2-hydroxy-2,2-diphenyl-acetoxy)-1-(isoxazol-3-ylcarbamoyl-methyl)-1-azonia-bicyclo-[2.2.2]octane bromid |
-
2004
- 2004-04-29 AR ARP040101468A patent/AR044134A1/es not_active Application Discontinuation
- 2004-04-30 US US10/554,558 patent/US20070060563A1/en not_active Abandoned
- 2004-04-30 ES ES04730519T patent/ES2331185T3/es not_active Expired - Lifetime
- 2004-04-30 DE DE602004022805T patent/DE602004022805D1/de not_active Expired - Lifetime
- 2004-04-30 RU RU2005137360/04A patent/RU2363700C2/ru not_active IP Right Cessation
- 2004-04-30 TW TW093112339A patent/TWI340139B/zh not_active IP Right Cessation
- 2004-04-30 PE PE2004000435A patent/PE20050465A1/es not_active Application Discontinuation
- 2004-04-30 CA CA2523436A patent/CA2523436C/en not_active Expired - Fee Related
- 2004-04-30 CL CL200400918A patent/CL2004000918A1/es unknown
- 2004-04-30 NZ NZ542995A patent/NZ542995A/en not_active IP Right Cessation
- 2004-04-30 WO PCT/EP2004/004605 patent/WO2004096800A2/en active Application Filing
- 2004-04-30 SI SI200431277T patent/SI1631569T1/sl unknown
- 2004-04-30 JP JP2006505341A patent/JP4416786B2/ja not_active Expired - Fee Related
- 2004-04-30 BR BRPI0410238-0A patent/BRPI0410238A/pt not_active IP Right Cessation
- 2004-04-30 MX MXPA05011739A patent/MXPA05011739A/es active IP Right Grant
- 2004-04-30 AT AT04730519T patent/ATE440840T1/de active
- 2004-04-30 EP EP04730519A patent/EP1631569B1/de not_active Expired - Lifetime
- 2004-04-30 MY MYPI20041637A patent/MY142652A/en unknown
- 2004-04-30 AU AU2004234069A patent/AU2004234069B2/en not_active Ceased
- 2004-04-30 KR KR1020057020776A patent/KR100896544B1/ko not_active IP Right Cessation
- 2004-04-30 PT PT04730519T patent/PT1631569E/pt unknown
- 2004-04-30 DK DK04730519T patent/DK1631569T3/da active
- 2004-04-30 PL PL04730519T patent/PL1631569T3/pl unknown
-
2005
- 2005-10-27 IL IL171591A patent/IL171591A/en not_active IP Right Cessation
- 2005-10-28 HR HR20050933A patent/HRP20050933A2/xx not_active Application Discontinuation
- 2005-11-01 EC EC2005006134A patent/ECSP056134A/es unknown
- 2005-11-03 CO CO05112195A patent/CO5700782A2/es not_active Application Discontinuation
- 2005-11-08 MA MA28583A patent/MA27775A1/fr unknown
- 2005-11-30 IS IS8158A patent/IS2746B/is unknown
- 2005-12-01 NO NO20055688A patent/NO20055688L/no not_active Application Discontinuation
-
2006
- 2006-07-17 HK HK06107974.9A patent/HK1087704A1/xx not_active IP Right Cessation
-
2009
- 2009-10-20 US US12/582,291 patent/US8168654B2/en not_active Expired - Fee Related
- 2009-11-25 CY CY20091101230T patent/CY1109655T1/el unknown
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |