PL2231642T3 - Pirymidyny jako inhibitory kinazy - Google Patents

Pirymidyny jako inhibitory kinazy

Info

Publication number
PL2231642T3
PL2231642T3 PL09700452T PL09700452T PL2231642T3 PL 2231642 T3 PL2231642 T3 PL 2231642T3 PL 09700452 T PL09700452 T PL 09700452T PL 09700452 T PL09700452 T PL 09700452T PL 2231642 T3 PL2231642 T3 PL 2231642T3
Authority
PL
Poland
Prior art keywords
pyrimidines
kinase inhibitors
kinase
inhibitors
Prior art date
Application number
PL09700452T
Other languages
English (en)
Inventor
Peter Hunt
Catherine Leblanc
Robert Alexander Pulz
Nikolaus Johannes Stiefl
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PL2231642T3 publication Critical patent/PL2231642T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P31/20—Antivirals for DNA viruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
PL09700452T 2008-01-11 2009-01-09 Pirymidyny jako inhibitory kinazy PL2231642T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08150194 2008-01-11
EP08157985 2008-06-10
PCT/EP2009/050222 WO2009087224A1 (en) 2008-01-11 2009-01-09 Pyrimidines as kinase inhibitors
EP09700452.7A EP2231642B1 (en) 2008-01-11 2009-01-09 Pyrimidines as kinase inhibitors

Publications (1)

Publication Number Publication Date
PL2231642T3 true PL2231642T3 (pl) 2014-04-30

Family

ID=40551454

Family Applications (1)

Application Number Title Priority Date Filing Date
PL09700452T PL2231642T3 (pl) 2008-01-11 2009-01-09 Pirymidyny jako inhibitory kinazy

Country Status (14)

Country Link
US (1) US8431578B2 (pl)
EP (1) EP2231642B1 (pl)
JP (1) JP5584138B2 (pl)
KR (1) KR20100113557A (pl)
CN (1) CN101910153B (pl)
AU (1) AU2009203693B2 (pl)
BR (1) BRPI0906838A2 (pl)
CA (1) CA2711637A1 (pl)
EA (1) EA201001129A1 (pl)
ES (1) ES2442930T3 (pl)
MX (1) MX2010007604A (pl)
PL (1) PL2231642T3 (pl)
PT (1) PT2231642E (pl)
WO (1) WO2009087224A1 (pl)

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MX2023000519A (es) 2020-07-15 2023-02-13 Chiesi Farm Spa Derivados de pirido-oxazina-amino como inhibidores de alk5.
EP4182322B1 (en) 2020-07-15 2024-04-24 Chiesi Farmaceutici S.p.A. Pyrido oxazine derivatives as alk5 inhibitors
KR20230051500A (ko) 2020-07-15 2023-04-18 키에시 파르마슈티시 엣스. 피. 에이. Alk5 억제제로서 피리다진일 아미노 유도체
WO2022136221A1 (en) 2020-12-23 2022-06-30 Chiesi Farmaceutici S.P.A. Pyrido oxazine derivatives as alk5 inhibitors
WO2023046698A1 (en) 2021-09-21 2023-03-30 Chiesi Farmaceutici S.P.A. Pyridazinyl amino derivatives as alk5 inhibitors
WO2023135107A1 (en) * 2022-01-11 2023-07-20 Chiesi Farmaceutici S.P.A. Pyridazinyl amino derivatives as alk5 inhibitors
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US20100298337A1 (en) 2010-11-25
KR20100113557A (ko) 2010-10-21
AU2009203693B2 (en) 2012-06-07
ES2442930T3 (es) 2014-02-14
BRPI0906838A2 (pt) 2015-07-14
AU2009203693A1 (en) 2009-07-16
EP2231642B1 (en) 2013-10-23
PT2231642E (pt) 2014-03-12
JP2011509278A (ja) 2011-03-24
CN101910153B (zh) 2014-01-22
WO2009087224A1 (en) 2009-07-16
EA201001129A1 (ru) 2011-02-28
EP2231642A1 (en) 2010-09-29
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CA2711637A1 (en) 2009-07-16
US8431578B2 (en) 2013-04-30

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