DK0888356T3 - Kondenserede 2,3-benzodiazepinderivater og deres anvendelse som AMPA-receptohaemmere - Google Patents

Kondenserede 2,3-benzodiazepinderivater og deres anvendelse som AMPA-receptohaemmere

Info

Publication number: DK0888356T3
Authority: DK; Denmark
Prior art keywords: condensed; receptor inhibitors; ampa receptor; benzodiazepine derivatives; hydrogen
Prior art date: 1996-02-01

Application number

DK97916315T

Other languages

English (en)

Inventor

Ernese Csuzdi

Tamas Hamori

Gizella Abraham

Sandor Solyom

Istvan Tarnawa

Pal Berzsenyi

Ferenc Andrasi

Istvan Ling

Antal Simay

Melinda Gal

Eszter Szentkuti

Marta Szoellosy

Istvan Pallagi

Katalin Horvath

Original Assignee

Schering Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-01

Filing date

1997-01-29

Publication date

2002-06-03

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7785064&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0888356(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-01-29 Application filed by Schering Ag filed Critical Schering Ag

2002-06-03 Application granted granted Critical

2002-06-03 Publication of DK0888356T3 publication Critical patent/DK0888356T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems

DK97916315T 1996-02-01 1997-01-29 Kondenserede 2,3-benzodiazepinderivater og deres anvendelse som AMPA-receptohaemmere DK0888356T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19604919A DE19604919A1 (de)	1996-02-01	1996-02-01	Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
PCT/DE1997/000234 WO1997028163A1 (de)	1996-02-01	1997-01-29	Kondensierte 2,3-benzodiazepin derivate und deren verwendung als ampa-rezeptoren-hemmer

Publications (1)

Publication Number	Publication Date
DK0888356T3 true DK0888356T3 (da)	2002-06-03

Family

ID=7785064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97916315T DK0888356T3 (da)	1996-02-01	1997-01-29	Kondenserede 2,3-benzodiazepinderivater og deres anvendelse som AMPA-receptohaemmere

Country Status (31)

Country	Link
US (2)	US6323197B1 (da)
EP (1)	EP0888356B1 (da)
JP (1)	JP4141499B2 (da)
KR (1)	KR100465269B1 (da)
CN (1)	CN1096464C (da)
AT (1)	ATE214703T1 (da)
AU (1)	AU724956B2 (da)
BG (1)	BG63394B1 (da)
BR (1)	BR9707335A (da)
CA (1)	CA2245539C (da)
CZ (1)	CZ289658B6 (da)
DE (2)	DE19604919A1 (da)
DK (1)	DK0888356T3 (da)
EE (1)	EE04017B1 (da)
ES (1)	ES2173435T3 (da)
HK (1)	HK1018782A1 (da)
HU (1)	HU224636B1 (da)
IL (1)	IL125480A (da)
IS (1)	IS2103B (da)
MY (1)	MY119140A (da)
NO (1)	NO983510L (da)
NZ (1)	NZ331187A (da)
PL (1)	PL187128B1 (da)
PT (1)	PT888356E (da)
RU (1)	RU2179557C2 (da)
SK (1)	SK283563B6 (da)
TR (1)	TR199801485T2 (da)
TW (1)	TW438801B (da)
UA (1)	UA56157C2 (da)
WO (1)	WO1997028163A1 (da)
ZA (1)	ZA97848B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP9701325A1 (hu)	1997-07-31	2000-08-28	Gyógyszerkutató Intézet Kft.	Új 2,3-benzodiazepin-származékok
UA67749C2 (uk) *	1997-08-12	2004-07-15	Егіш Дьйодьсердьяр Рт.	Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
JP2002519373A (ja) *	1998-07-02	2002-07-02	エーザイ株式会社	製薬組成物及びそれらの使用
US6887867B2 (en) *	2000-06-16	2005-05-03	Transgenomic, Inc.	5H-2,3-benzodiazepine antagonists of excitatory amino acid receptors
DE10041671C1 (de) *	2000-08-10	2002-06-13	Schering Ag	Verfahren zur Herstellung von Imidazo[1,2-c][2,3]benzodiazepinen sowie Phenylessigsäureester und Oxazol-Derivate als Zwischenprodukte bei deren Herstellung
WO2005113434A1 (en) *	2004-03-25	2005-12-01	William Marsh Rice University	Functionalization of carbon nanotubes in acidic media
US20060166969A1 (en) *	2005-01-14	2006-07-27	Turski Lechoslaw A	AMPA antagonists for the treatment of dizziness, including vertigo and Meniere's disorder
EP2338492A1 (en)	2009-12-24	2011-06-29	Universidad del Pais Vasco	Methods and compositions for the treatment of alzheimer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5891871A (en)	1996-03-21	1999-04-06	Cocensys, Inc.	Substituted 2,3-benzodiazepin-4-ones and the use thereof
HU9600871D0 (en) *	1996-04-04	1996-05-28	Gyogyszerkutato Intezet	New 2,3-benzodiazepine derivatives

1996
- 1996-02-01 DE DE19604919A patent/DE19604919A1/de not_active Withdrawn
1997
- 1997-01-29 CN CN97192012A patent/CN1096464C/zh not_active Expired - Fee Related
- 1997-01-29 DE DE59706686T patent/DE59706686D1/de not_active Expired - Lifetime
- 1997-01-29 WO PCT/DE1997/000234 patent/WO1997028163A1/de active IP Right Grant
- 1997-01-29 ES ES97916315T patent/ES2173435T3/es not_active Expired - Lifetime
- 1997-01-29 DK DK97916315T patent/DK0888356T3/da active
- 1997-01-29 EE EE9800225A patent/EE04017B1/xx not_active IP Right Cessation
- 1997-01-29 PT PT97916315T patent/PT888356E/pt unknown
- 1997-01-29 US US09/117,508 patent/US6323197B1/en not_active Expired - Fee Related
- 1997-01-29 JP JP52724897A patent/JP4141499B2/ja not_active Expired - Fee Related
- 1997-01-29 IL IL12548097A patent/IL125480A/en not_active IP Right Cessation
- 1997-01-29 BR BR9707335A patent/BR9707335A/pt not_active IP Right Cessation
- 1997-01-29 HU HU9901417A patent/HU224636B1/hu not_active IP Right Cessation
- 1997-01-29 PL PL97328224A patent/PL187128B1/pl not_active IP Right Cessation
- 1997-01-29 UA UA98084653A patent/UA56157C2/uk unknown
- 1997-01-29 KR KR10-1998-0705917A patent/KR100465269B1/ko not_active IP Right Cessation
- 1997-01-29 AU AU25029/97A patent/AU724956B2/en not_active Ceased
- 1997-01-29 CZ CZ19982427A patent/CZ289658B6/cs not_active IP Right Cessation
- 1997-01-29 AT AT97916315T patent/ATE214703T1/de not_active IP Right Cessation
- 1997-01-29 RU RU98116292/04A patent/RU2179557C2/ru not_active IP Right Cessation
- 1997-01-29 CA CA002245539A patent/CA2245539C/en not_active Expired - Fee Related
- 1997-01-29 EP EP97916315A patent/EP0888356B1/de not_active Expired - Lifetime
- 1997-01-29 TR TR1998/01485T patent/TR199801485T2/xx unknown
- 1997-01-29 NZ NZ331187A patent/NZ331187A/xx unknown
- 1997-01-29 SK SK1033-98A patent/SK283563B6/sk unknown
- 1997-01-31 MY MYPI97000379A patent/MY119140A/en unknown
- 1997-01-31 ZA ZA9700848A patent/ZA97848B/xx unknown
- 1997-02-01 TW TW086101218A patent/TW438801B/zh not_active IP Right Cessation
1998
- 1998-07-06 IS IS4794A patent/IS2103B/is unknown
- 1998-07-29 BG BG102658A patent/BG63394B1/bg unknown
- 1998-07-30 NO NO983510A patent/NO983510L/no unknown
1999
- 1999-09-02 HK HK99103802A patent/HK1018782A1/xx not_active IP Right Cessation
2001
- 2001-11-27 US US09/993,646 patent/US6600036B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
ES2173435T3 (es)	2002-10-16
WO1997028163A1 (de)	1997-08-07
KR100465269B1 (ko)	2005-04-14
DE19604919A1 (de)	1997-08-07
CZ289658B6 (cs)	2002-03-13
NO983510L (no)	1998-09-30
IL125480A0 (en)	1999-03-12
EP0888356B1 (de)	2002-03-20
CZ242798A3 (cs)	1999-01-13
EE04017B1 (et)	2003-04-15
HUP9901417A2 (hu)	1999-08-30
US6600036B2 (en)	2003-07-29
CN1096464C (zh)	2002-12-18
BR9707335A (pt)	1999-07-20
HK1018782A1 (en)	2000-01-07
TW438801B (en)	2001-06-07
JP4141499B2 (ja)	2008-08-27
MY119140A (en)	2005-04-30
HU224636B1 (hu)	2005-12-28
NZ331187A (en)	2000-01-28
UA56157C2 (uk)	2003-05-15
SK283563B6 (sk)	2003-09-11
RU2179557C2 (ru)	2002-02-20
PT888356E (pt)	2002-09-30
SK103398A3 (en)	1999-01-11
US20020052364A1 (en)	2002-05-02
EE9800225A (et)	1998-12-15
EP0888356A1 (de)	1999-01-07
CA2245539A1 (en)	1997-08-07
DE59706686D1 (de)	2002-04-25
PL187128B1 (pl)	2004-05-31
BG102658A (en)	1999-06-30
AU724956B2 (en)	2000-10-05
IS2103B (is)	2006-05-15
TR199801485T2 (xx)	1998-10-21
PL328224A1 (en)	1999-01-18
IS4794A (is)	1998-07-06
CA2245539C (en)	2005-10-04
CN1210538A (zh)	1999-03-10
AU2502997A (en)	1997-08-22
JP2000503997A (ja)	2000-04-04
NO983510D0 (no)	1998-07-30
KR19990082192A (ko)	1999-11-25
ATE214703T1 (de)	2002-04-15
BG63394B1 (bg)	2001-12-29
IL125480A (en)	2002-07-25
US6323197B1 (en)	2001-11-27
ZA97848B (en)	1997-08-04
HUP9901417A3 (en)	2001-11-28

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HUP0105414A2 (hu)	2002-05-29	Pirrolo-izokinolin-, azepino- és diazepino-indol-származékok, alkalmazásuk és az ezeket tartalmazó gyógyszerkészítmények
AP1246A (en)	2004-02-07	Substituted pyrazoles as p38 Kinase inhibitors.
AP2001002172A0 (en)	2001-06-30	Substituted pyrazoles as p38 kinase inhibitors
GEP20063915B (en)	2006-09-11	PYRROLOTRIAZINE COMPOUNDS USEFUL AS KINASE INHIBITORS AND USE THEREOF FOR TREATING p38 KINASE-ASSOCIATED CONDITIONS
TR200201505T2 (tr)	2003-01-21	Terapötik maddeler olarak pirazolopirimidinler
MX9806171A (es)	1998-10-31	Derivados 2,3-benzodiazepina y sus usos como inhibidores del receptor-ampa.
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