IS2103B - Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar - Google Patents

Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar

Info

Publication number: IS2103B
Authority: IS; Iceland
Prior art keywords: densified; receptor inhibitors; ampa receptor; benzodiazepine derivatives; hydrogen
Prior art date: 1996-02-01

Application number

IS4794A

Other languages

English (en)

Other versions

IS4794A (is

Inventor

Csuzdi Ernese

ibrah βm Gizella

βn Tarnawa Istv

Andr βsi Ferenc

βs H βmori Tam

βndor Solyom S

βl Berzsenyi P

βn Ling Istv

Simay Antal

Horv βth Katalin

βrta Szôllosy M

G βl Melinda

Szentkuti Eszter

βn Pallagi Istv

Original Assignee

Schering Aktiengesellschaft

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-02-01

Filing date

1998-07-06

Publication date

2006-05-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7785064&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IS2103(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-07-06 Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft

1998-07-06 Publication of IS4794A publication Critical patent/IS4794A/is

2006-05-15 Publication of IS2103B publication Critical patent/IS2103B/is

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/14—Ortho-condensed systems

IS4794A 1996-02-01 1998-07-06 Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar IS2103B (is)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19604919A DE19604919A1 (de)	1996-02-01	1996-02-01	Neue 2,3-Benzodiazepinderivate, deren Herstellung und Verwendung als Arzneimittel
PCT/DE1997/000234 WO1997028163A1 (de)	1996-02-01	1997-01-29	Kondensierte 2,3-benzodiazepin derivate und deren verwendung als ampa-rezeptoren-hemmer

Publications (2)

Publication Number	Publication Date
IS4794A IS4794A (is)	1998-07-06
IS2103B true IS2103B (is)	2006-05-15

Family

ID=7785064

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IS4794A IS2103B (is)	1996-02-01	1998-07-06	Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar

Country Status (31)

Country	Link
US (2)	US6323197B1 (is)
EP (1)	EP0888356B1 (is)
JP (1)	JP4141499B2 (is)
KR (1)	KR100465269B1 (is)
CN (1)	CN1096464C (is)
AT (1)	ATE214703T1 (is)
AU (1)	AU724956B2 (is)
BG (1)	BG63394B1 (is)
BR (1)	BR9707335A (is)
CA (1)	CA2245539C (is)
CZ (1)	CZ289658B6 (is)
DE (2)	DE19604919A1 (is)
DK (1)	DK0888356T3 (is)
EE (1)	EE04017B1 (is)
ES (1)	ES2173435T3 (is)
HK (1)	HK1018782A1 (is)
HU (1)	HU224636B1 (is)
IL (1)	IL125480A (is)
IS (1)	IS2103B (is)
MY (1)	MY119140A (is)
NO (1)	NO983510L (is)
NZ (1)	NZ331187A (is)
PL (1)	PL187128B1 (is)
PT (1)	PT888356E (is)
RU (1)	RU2179557C2 (is)
SK (1)	SK283563B6 (is)
TR (1)	TR199801485T2 (is)
TW (1)	TW438801B (is)
UA (1)	UA56157C2 (is)
WO (1)	WO1997028163A1 (is)
ZA (1)	ZA97848B (is)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HUP9701325A1 (hu)	1997-07-31	2000-08-28	Gyógyszerkutató Intézet Kft.	Új 2,3-benzodiazepin-származékok
UA67749C2 (uk) *	1997-08-12	2004-07-15	Егіш Дьйодьсердьяр Рт.	Похідна 8-заміщеного-9н-1,3-діоксол/4,5-h//2,3/бензодіазепіну з властивостями амра/каїнатного антагоніста, спосіб одержання похідних, фармацевтична композиція (варіанти), спосіб її одержання та спосіб лікування
JP2002519373A (ja) *	1998-07-02	2002-07-02	エーザイ株式会社	製薬組成物及びそれらの使用
US6887867B2 (en) *	2000-06-16	2005-05-03	Transgenomic, Inc.	5H-2,3-benzodiazepine antagonists of excitatory amino acid receptors
DE10041671C1 (de)	2000-08-10	2002-06-13	Schering Ag	Verfahren zur Herstellung von Imidazo[1,2-c][2,3]benzodiazepinen sowie Phenylessigsäureester und Oxazol-Derivate als Zwischenprodukte bei deren Herstellung
US20070280876A1 (en) *	2004-03-25	2007-12-06	William Marsh Rice University	Functionalization of Carbon Nanotubes in Acidic Media
US20060166969A1 (en) *	2005-01-14	2006-07-27	Turski Lechoslaw A	AMPA antagonists for the treatment of dizziness, including vertigo and Meniere's disorder
EP2338492A1 (en)	2009-12-24	2011-06-29	Universidad del Pais Vasco	Methods and compositions for the treatment of alzheimer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5891871A (en)	1996-03-21	1999-04-06	Cocensys, Inc.	Substituted 2,3-benzodiazepin-4-ones and the use thereof
HU9600871D0 (en) *	1996-04-04	1996-05-28	Gyogyszerkutato Intezet	New 2,3-benzodiazepine derivatives

1996
- 1996-02-01 DE DE19604919A patent/DE19604919A1/de not_active Withdrawn
1997
- 1997-01-29 AT AT97916315T patent/ATE214703T1/de not_active IP Right Cessation
- 1997-01-29 EP EP97916315A patent/EP0888356B1/de not_active Expired - Lifetime
- 1997-01-29 ES ES97916315T patent/ES2173435T3/es not_active Expired - Lifetime
- 1997-01-29 JP JP52724897A patent/JP4141499B2/ja not_active Expired - Fee Related
- 1997-01-29 BR BR9707335A patent/BR9707335A/pt not_active IP Right Cessation
- 1997-01-29 SK SK1033-98A patent/SK283563B6/sk unknown
- 1997-01-29 NZ NZ331187A patent/NZ331187A/xx unknown
- 1997-01-29 PL PL97328224A patent/PL187128B1/pl not_active IP Right Cessation
- 1997-01-29 US US09/117,508 patent/US6323197B1/en not_active Expired - Fee Related
- 1997-01-29 AU AU25029/97A patent/AU724956B2/en not_active Ceased
- 1997-01-29 IL IL12548097A patent/IL125480A/en not_active IP Right Cessation
- 1997-01-29 DE DE59706686T patent/DE59706686D1/de not_active Expired - Lifetime
- 1997-01-29 HU HU9901417A patent/HU224636B1/hu not_active IP Right Cessation
- 1997-01-29 CZ CZ19982427A patent/CZ289658B6/cs not_active IP Right Cessation
- 1997-01-29 EE EE9800225A patent/EE04017B1/xx not_active IP Right Cessation
- 1997-01-29 KR KR10-1998-0705917A patent/KR100465269B1/ko not_active IP Right Cessation
- 1997-01-29 TR TR1998/01485T patent/TR199801485T2/xx unknown
- 1997-01-29 RU RU98116292/04A patent/RU2179557C2/ru not_active IP Right Cessation
- 1997-01-29 CA CA002245539A patent/CA2245539C/en not_active Expired - Fee Related
- 1997-01-29 UA UA98084653A patent/UA56157C2/uk unknown
- 1997-01-29 CN CN97192012A patent/CN1096464C/zh not_active Expired - Fee Related
- 1997-01-29 WO PCT/DE1997/000234 patent/WO1997028163A1/de active IP Right Grant
- 1997-01-29 PT PT97916315T patent/PT888356E/pt unknown
- 1997-01-29 DK DK97916315T patent/DK0888356T3/da active
- 1997-01-31 ZA ZA9700848A patent/ZA97848B/xx unknown
- 1997-01-31 MY MYPI97000379A patent/MY119140A/en unknown
- 1997-02-01 TW TW086101218A patent/TW438801B/zh not_active IP Right Cessation
1998
- 1998-07-06 IS IS4794A patent/IS2103B/is unknown
- 1998-07-29 BG BG102658A patent/BG63394B1/bg unknown
- 1998-07-30 NO NO983510A patent/NO983510L/no unknown
1999
- 1999-09-02 HK HK99103802A patent/HK1018782A1/xx not_active IP Right Cessation
2001
- 2001-11-27 US US09/993,646 patent/US6600036B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL125480A (en)	2002-07-25
HUP9901417A2 (hu)	1999-08-30
PT888356E (pt)	2002-09-30
TW438801B (en)	2001-06-07
JP4141499B2 (ja)	2008-08-27
ATE214703T1 (de)	2002-04-15
DK0888356T3 (da)	2002-06-03
US20020052364A1 (en)	2002-05-02
CZ289658B6 (cs)	2002-03-13
PL187128B1 (pl)	2004-05-31
TR199801485T2 (xx)	1998-10-21
CZ242798A3 (cs)	1999-01-13
KR100465269B1 (ko)	2005-04-14
AU724956B2 (en)	2000-10-05
NZ331187A (en)	2000-01-28
PL328224A1 (en)	1999-01-18
DE19604919A1 (de)	1997-08-07
EE9800225A (et)	1998-12-15
WO1997028163A1 (de)	1997-08-07
JP2000503997A (ja)	2000-04-04
EE04017B1 (et)	2003-04-15
DE59706686D1 (de)	2002-04-25
BG102658A (en)	1999-06-30
IL125480A0 (en)	1999-03-12
NO983510L (no)	1998-09-30
UA56157C2 (uk)	2003-05-15
CN1096464C (zh)	2002-12-18
BG63394B1 (bg)	2001-12-29
ZA97848B (en)	1997-08-04
MY119140A (en)	2005-04-30
KR19990082192A (ko)	1999-11-25
HU224636B1 (hu)	2005-12-28
ES2173435T3 (es)	2002-10-16
US6323197B1 (en)	2001-11-27
CA2245539C (en)	2005-10-04
CA2245539A1 (en)	1997-08-07
SK283563B6 (sk)	2003-09-11
RU2179557C2 (ru)	2002-02-20
EP0888356B1 (de)	2002-03-20
HUP9901417A3 (en)	2001-11-28
US6600036B2 (en)	2003-07-29
NO983510D0 (no)	1998-07-30
IS4794A (is)	1998-07-06
SK103398A3 (en)	1999-01-11
HK1018782A1 (en)	2000-01-07
EP0888356A1 (de)	1999-01-07
BR9707335A (pt)	1999-07-20
CN1210538A (zh)	1999-03-10
AU2502997A (en)	1997-08-22

Publication	Publication Date	Title
GEP20063915B (en)	2006-09-11	PYRROLOTRIAZINE COMPOUNDS USEFUL AS KINASE INHIBITORS AND USE THEREOF FOR TREATING p38 KINASE-ASSOCIATED CONDITIONS
AP1246A (en)	2004-02-07	Substituted pyrazoles as p38 Kinase inhibitors.
YU35601A (sh)	2005-07-19	SUPSTITUISANI PIRAZOLI KAO INHIBITORI p38 KINAZE
HUP0105414A2 (hu)	2002-05-29	Pirrolo-izokinolin-, azepino- és diazepino-indol-származékok, alkalmazásuk és az ezeket tartalmazó gyógyszerkészítmények
BG105596A (en)	2002-02-28	Substituted benzimidazoles and their use as parp inhibitors
HUP0202757A2 (hu)	2002-12-28	Metabotróp glutamát receptor antagonista heteropoliciklusos vegyületek, ezeket tartalmazó gyógyszerkészítmények és a vegyületek alkalmazása
MY105438A (en)	1994-10-31	3-aminopiperidine derivatives and related nitrogen containing heterocycles.
DE69719350D1 (de)	2003-04-03	2-pyrimidinamin derivaten und verfahrens zu deren herstellung
HRP20031098B1 (en)	2012-03-31	Beta-amino tetrahydroimidazo (1,2-a) pyrazines and tetrahydrotrioazolo (4,3-a) pyrazines as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
FI970150A (fi)	1997-01-14	Substituoituja pyrimidiiniyhdisteitä ja niiden käyttö
MX9806171A (es)	1998-10-31	Derivados 2,3-benzodiazepina y sus usos como inhibidores del receptor-ampa.
SE9702564D0 (sv)	1997-07-02	New compounds
ES2101858T3 (es)	1997-07-16	Derivados de geneserina como inhibidores de colinesterasa.
HUP0303034A2 (hu)	2003-12-29	Új 7-azaindol-származékok, foszfodiészteráz-4 inhibitorjakénti alkalmazásuk és eljárás az előállításukra
ES2140381T3 (es)	2000-03-01	Nuevas 4h-pirido-(1,2-a)pirimidin-4-onas disustituidas en 2,9.
IS2103B (is)	2006-05-15	Þéttaðar 2,3-bensódíasepín afleiður og notkun þeirra sem AMPA-viðtakahindrar
HUP0004142A2 (hu)	2001-05-28	5-HT1F agonista hatású karboxamidszármazékok és a vegyületeket tartalmazó gyógyászati készítmények
TW429255B (en)	2001-04-11	Pyrazine compounds having treatment of central nervous system diseases and disorders
TW360650B (en)	1999-06-11	Pyridin-2-ylmethyloxy-pyridin-5-ylcarbamoyl-indoline derivatives, a process for the preparation thereof, and a pharmaceutical composition comprising them
MX9706014A (es)	1998-02-28	Derivados de xanteno y acridina y su empleo.
ATE214056T1 (de)	2002-03-15	Benzodiazepinderivate
MY141481A (en)	2010-04-30	Substituted pyrazoles as p38 kinase inhibitors
MY104554A (en)	1994-04-30	Benzofuran derivatives.