DE297436T1 - Behandlung von hyperhidrose, ichtyosis und faltenbildung. - Google Patents

Behandlung von hyperhidrose, ichtyosis und faltenbildung.

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Publication number
DE297436T1
DE297436T1 DE198888110037T DE88110037T DE297436T1 DE 297436 T1 DE297436 T1 DE 297436T1 DE 198888110037 T DE198888110037 T DE 198888110037T DE 88110037 T DE88110037 T DE 88110037T DE 297436 T1 DE297436 T1 DE 297436T1
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Prior art keywords
compound
group
azelaic acid
ester
salts
Prior art date
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Pending
Application number
DE198888110037T
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English (en)
Inventor
Carl Richard Ontario Oreg. Thornfeldt
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Individual
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Individual
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Publication date
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Publication of DE297436T1 publication Critical patent/DE297436T1/de
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/362—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Claims (13)

110 037.4 Carl Richard Thornfeld N-.W. 2nd Avenue Ontario, Oregon 97914, USA Unser Z.: P/Sv-T 2506 Behandlung von Hyperhidrose, Ichthyosis und Faltenbildung Patentansprüche
1. Verfahren zur Behandlung von Haut, die unter Hyperhidrose, Ichthiose oder Faltenbildung leidet, wobei das Verfahren das Auftragen einer therapeutisch wirksamen Menge
einer Verbindung auf den betroffenen Bereich umfaßt, die )
aus der aus Mono- und Dikarbonsäuren mit 4 bis 18 Kohlenstoffatomen, Merkaptoderivaten derselben, Salzen derselben und Estern derselben besteht.
2. Verfahren nach Anspruch 1, bei dem die Verbindung aus der Gruppe ausgewählt wird, die aus Azelainsäure, Merkaptoderivaten derselben, Salzen derselben und Estern derselben besteht.
3. Verfahren nach Anspruch 1, bei dem die Verbindung Azelainsäure ist.
4. Verfahren nach Anspruch 1, bei dem die Verbindung ein aus der Gruppe ausgewähltes Mitglied ist, welche aus Monoglyzerid und Monosaccharoseestern von Azelainsäure besteht.
5. Verfahren zur Behandlung einer Haut, die an Hyperhidrose
leidet, wobei das Verfahren das Auftragen einer therapeutisch wirksamen Menge einer dermatologischen Formulierung auf das betroffene Gebiet umfaßt, welche von 0,1 bis etwa 40 Gew.-% einer Verbindung enthält, die aus Mono- und
Dikarbonsäuren mit 4 bis 18 Kohlenstoffatomen,
Merkaptoderivaten derselben, Salzen derselben und Polyol- und Oligosaccharid-Estern derselben besteht.
6. Verfahren nach Anspruch 5, bei dem die Verbindung ein aus der aus Azelainsäure, dem Monoglyzeridester und dem Monosaccharoseester derselben bestehenden Gruppe ausgewählt
ist.
7. Verfahren für die Behandlung einer an Ichthiose leidenden Haut, wobei das Verfahren das Auftragen einer therapeutisch wirksamen Menge einer dermatologischen Formulierung
T auf das betroffene Gebiet umfaßt, welche von etwa 0,1 bis
etwa 40 Gew.-% einer Verbindung enthält, die aus der aus Mono- und Dikarbonsäuren mit 4 bis 18 Kohlenstoffatomen, Merkaptoderivaten derselben, Salzen derselben und Polyol- und Oligosaccharid-Estern derselben bestehenden Gruppe
ausgewählt, ist.
8. Verfahren nach Anspruch 7, bei dem die Verbindung ein aus der aus Azelainsäure, dem Monoglyzeridester und dem Monosaccharoseester derselben bestehenden Gruppe ausgewähltes Mitglied ist.
9. Verfahren zur Behandlung einer an Keratosis pilaris leidenden Haut, wobei das Verfahren das Auftragen einer
therapeutisch wirksamen Menge "einer dermatologischen Formulierung auf das betroffene Gebiet umfaßt, die Von 0,1
bis etwa 4 0 Gew.-% einer Verbindung enthält, welche aus
der aus Mono- und Dikarbonsäuren mit 7 bis 13 Kohlenstoffatomen, Merkaptoderivaten derselben, Salzen derselben und
Polyol- und Oligosaccharid-Estern derselben bestehenden Gruppe ausgewählt ist.
10. Verfahren nach Anspruch 9, bei dem die Verbindung ein aus der aus Azelainsäure, dem Monoglyzeridester und dem Monosaccharoseester derselben ausgewähltes Mitglied ist.
11. Verfahren zur Behandlung einer an Faltenbildung infolge von Eigen-Alterung oder Licht-Alterung leidenden Haut, wobei das Verfahren das Auftragen einer therapeutisch wirksamen Menge einer dermatologischen Formulierung auf das betroffene Gebiet umfaßt, welche von 0,1 bis etwa 4 0 Gew.-% einer Verbindung enthält, die aus der aus Mono- und Dikarbonsäuren mit 7 bis 13 Kohlenstoffatomen, Merkaptoderivaten derselben, Salzen derselben und Polyol- und Oligosaccharid-Estern derselben bestehenden Gruppe ausgewählt ist.
12. Verfahren nach Anspruch 11, bei dem die Verbindung ein aus der aus Azelainsäure, dem Monoglyzerid-Ester und dem Monosaccharoseester derselben bestehenden Gruppe ausgewähltes Mitglied ist.
13. Verfahren zur Behandlung einer an Hyperhidrose, an Ichthiosis vulgaris mit oder ohne Keratosis pilaris oder an Faltenbildung leidenden Haut, wobei das Verfahren das Auftragen einer therapeutisch wirksamen Menge einer dermatologischen Formulierung auf die betroffene Fläche umfaßt, welche von etwa 5 bis etwa 20 Gew.-% Azelainsäure enthält.
DE198888110037T 1987-07-02 1988-06-23 Behandlung von hyperhidrose, ichtyosis und faltenbildung. Pending DE297436T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6907187A 1987-07-02 1987-07-02
US07/160,042 US4885282A (en) 1987-07-02 1988-03-08 Treatment of hyperhidrosis, ichthyosis and wrinkling

Publications (1)

Publication Number Publication Date
DE297436T1 true DE297436T1 (de) 1989-08-03

Family

ID=26749652

Family Applications (3)

Application Number Title Priority Date Filing Date
DE3853558T Expired - Fee Related DE3853558T2 (de) 1987-07-02 1988-06-23 Behandlung von Hyperhidrose und Ichtyosis.
DE198888110037T Pending DE297436T1 (de) 1987-07-02 1988-06-23 Behandlung von hyperhidrose, ichtyosis und faltenbildung.
DE3855489T Expired - Fee Related DE3855489T2 (de) 1987-07-02 1988-06-23 Behandlung von Hautfalten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE3853558T Expired - Fee Related DE3853558T2 (de) 1987-07-02 1988-06-23 Behandlung von Hyperhidrose und Ichtyosis.

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE3855489T Expired - Fee Related DE3855489T2 (de) 1987-07-02 1988-06-23 Behandlung von Hautfalten

Country Status (4)

Country Link
US (1) US4885282A (de)
EP (2) EP0297436B1 (de)
JP (3) JP2608762B2 (de)
DE (3) DE3853558T2 (de)

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Also Published As

Publication number Publication date
JPH085785B2 (ja) 1996-01-24
JPS6429308A (en) 1989-01-31
EP0588379A3 (en) 1994-06-01
EP0297436B1 (de) 1995-04-12
JPH06298643A (ja) 1994-10-25
EP0297436A2 (de) 1989-01-04
JP2608762B2 (ja) 1997-05-14
DE3855489D1 (de) 1996-09-26
EP0297436A3 (de) 1991-05-15
DE3853558T2 (de) 1995-08-24
JP2538516B2 (ja) 1996-09-25
EP0588379A2 (de) 1994-03-23
US4885282A (en) 1989-12-05
DE3853558D1 (de) 1995-05-18
EP0588379B1 (de) 1996-08-21
DE3855489T2 (de) 1996-12-19
JPH06321779A (ja) 1994-11-22

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