US6083903A
(en)
*
|
1994-10-28 |
2000-07-04 |
Leukosite, Inc. |
Boronic ester and acid compounds, synthesis and uses
|
US6838477B2
(en)
*
|
1995-04-12 |
2005-01-04 |
President And Fellows Of Harvard College |
Lactacystin analogs
|
FR2758329B1
(fr)
*
|
1997-01-16 |
1999-02-12 |
Synthelabo |
Derives d'imidazole-4-butane boronique, leur preparation et leur utilisation en therapeutique
|
AU741802B2
(en)
*
|
1997-02-15 |
2001-12-13 |
Millennium Pharmaceuticals, Inc. |
Treatment of infarcts through inhibition of NF-kappaB
|
US6221888B1
(en)
*
|
1997-05-29 |
2001-04-24 |
Merck & Co., Inc. |
Sulfonamides as cell adhesion inhibitors
|
EP1017398A1
(de)
*
|
1997-09-25 |
2000-07-12 |
Proscript, Inc. |
Proteasome inhibitoren, inhibitoren des ubiquitinweges oder verbindungen, die mit der durch den ubiquitinweg enstehenden nf-kb aktivierung interferieren zur behandlung von entzündlichen und autoimmunerkrankungen
|
CA2304206A1
(en)
*
|
1997-09-29 |
1999-04-08 |
Point Therapeutics, Inc. |
Stimulation of hematopoietic cells in vitro
|
US6831057B2
(en)
*
|
1997-10-28 |
2004-12-14 |
The University Of North Carolina At Chapel Hill |
Use of NF-κB inhibition in combination therapy for cancer
|
CA2219867A1
(en)
*
|
1997-10-31 |
1999-04-30 |
Jiangping Wu |
The use of proteasome inhibitors for treating cancer, inflammation, autoimmune disease, graft rejection and septic shock
|
DE19802450A1
(de)
*
|
1998-01-23 |
1999-07-29 |
Hoechst Marion Roussel De Gmbh |
Ustilipide, Verfahren zu deren Herstellung sowie deren Verwendung
|
US6075150A
(en)
|
1998-01-26 |
2000-06-13 |
Cv Therapeutics, Inc. |
α-ketoamide inhibitors of 20S proteasome
|
US6617171B2
(en)
*
|
1998-02-27 |
2003-09-09 |
The General Hospital Corporation |
Methods for diagnosing and treating autoimmune disease
|
FR2779653B1
(fr)
|
1998-06-11 |
2002-12-20 |
Inst Nat Sante Rech Med |
Utilisation de composes modulateurs du proteasome en therapie
|
US6462019B1
(en)
|
1998-07-10 |
2002-10-08 |
Osteoscreen, Inc. |
Inhibitors of proteasomal activity and production for stimulating bone growth
|
US6838436B1
(en)
*
|
1998-07-10 |
2005-01-04 |
Osteoscreen Inc. |
Inhibitors of proteasomal activity for stimulating bone growth
|
US6902721B1
(en)
*
|
1998-07-10 |
2005-06-07 |
Osteoscreen, Inc. |
Inhibitors of proteasomal activity for stimulating bone growth
|
US6979697B1
(en)
*
|
1998-08-21 |
2005-12-27 |
Point Therapeutics, Inc. |
Regulation of substrate activity
|
EP0982317A1
(de)
*
|
1998-08-26 |
2000-03-01 |
Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. |
Bivalente Proteasome Inhibitore
|
IL142647A0
(en)
*
|
1998-10-20 |
2002-03-10 |
Millenium Pharmaceuticals Inc |
A method and kit for measuring proteasome activity
|
US6492333B1
(en)
*
|
1999-04-09 |
2002-12-10 |
Osteoscreen, Inc. |
Treatment of myeloma bone disease with proteasomal and NF-κB activity inhibitors
|
US6890904B1
(en)
*
|
1999-05-25 |
2005-05-10 |
Point Therapeutics, Inc. |
Anti-tumor agents
|
US6649593B1
(en)
*
|
1999-10-13 |
2003-11-18 |
Tularik Inc. |
Modulators of SREBP processing
|
AU2001287399A1
(en)
*
|
2000-08-16 |
2002-02-25 |
University Of Alberta |
Non-pressurized methods for the preparation of conjugated solid supports for boronic acids
|
US6919382B2
(en)
|
2000-08-31 |
2005-07-19 |
The Governors Of The University Of Alberta |
Preparation and uses of conjugated solid supports for boronic acids
|
EP1430903A1
(de)
*
|
2000-10-12 |
2004-06-23 |
Viromics Gmbh |
Verwendung von Proteasome Hemmern zur Behandlung von Virus-Infektionen
|
DK1355910T3
(da)
*
|
2001-01-25 |
2011-06-27 |
Us Of America Represented By The Secretary Dept Of Health And Human Services |
Formulering af borsyreforbindelser
|
CN1509183A
(zh)
|
2001-05-21 |
2004-06-30 |
|
蛋白酶体抑制剂在治疗干眼疾病中的用途
|
US7112588B2
(en)
*
|
2001-05-21 |
2006-09-26 |
Alcon, Inc. |
Use of proteasome inhibitors to treat dry eye disorders
|
PT1399468E
(pt)
*
|
2001-05-30 |
2006-05-31 |
Novartis Ag |
Derivados do acido 2-{[n-(2-amino-3-(heteroaril ou aril)propionil)-aminoacil]-amino}-alquilboronico
|
WO2003033507A1
(fr)
*
|
2001-10-12 |
2003-04-24 |
Kyorin Pharmaceutical Co., Ltd. |
Derives d'acide benzylmalonique et inhibiteurs de proteasomes les contenant
|
JPWO2003033506A1
(ja)
*
|
2001-10-12 |
2005-02-03 |
杏林製薬株式会社 |
アミノボラン酸誘導体およびそれを含有するプロテアソーム阻害薬
|
EP1463719A2
(de)
*
|
2002-01-08 |
2004-10-06 |
Eisai Co., Ltd |
Eponemycin und epoxomicin analoge und verwendungen davon
|
WO2003077928A1
(en)
*
|
2002-03-12 |
2003-09-25 |
Ariad Pharmaceuticals, Inc. |
Peptide analogues and uses thereof
|
CN100396679C
(zh)
*
|
2002-03-13 |
2008-06-25 |
詹森药业有限公司 |
用作组蛋白脱乙酰化酶抑制剂的哌嗪基、哌啶基和吗啉基衍生物
|
JP4648628B2
(ja)
|
2002-03-13 |
2011-03-09 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
ヒストンデアセチラーゼの新規な阻害剤としてのカルボニルアミノ誘導体
|
BR0307599A
(pt)
|
2002-03-13 |
2005-02-01 |
Janssen Pharmaceutica Nv |
Derivados de sulfonilamino como inibidores de histona deacetilase
|
EA007272B1
(ru)
|
2002-03-13 |
2006-08-25 |
Янссен Фармацевтика Н. В. |
Новые ингибиторы гистондеацетилазы
|
US20050203029A1
(en)
*
|
2002-04-05 |
2005-09-15 |
Ulrich Schubert |
Agents for treating <I>flaviviridae</I>infections
|
US7514579B2
(en)
*
|
2002-06-13 |
2009-04-07 |
Johns Hopkins University |
Boronic chalcone derivatives and uses thereof
|
WO2004004658A2
(en)
*
|
2002-07-09 |
2004-01-15 |
Point Therapeutics, Inc. |
Methods and compositions relating to isoleucine boroproline compounds
|
CA2495068A1
(en)
*
|
2002-08-14 |
2004-02-26 |
Janssen Pharmaceutica N.V. |
Use of nf-kappa b inhibitors for the treatment of mastitis
|
US20050176651A1
(en)
*
|
2002-09-09 |
2005-08-11 |
Trigen Limited |
Peptide boronic acids useful in making salts thereof
|
US20050282757A1
(en)
*
|
2002-09-09 |
2005-12-22 |
Trigen Limited |
Peptide boronic acid compounds useful in anticoagulation
|
US20050119226A1
(en)
*
|
2003-09-09 |
2005-06-02 |
Trigen Limited |
Methods for synthesizing organoboronic compounds and products thereof
|
US20050288253A1
(en)
*
|
2002-09-09 |
2005-12-29 |
Trigen Limited |
Boronic acid salts
|
US20060084592A1
(en)
*
|
2002-09-09 |
2006-04-20 |
Trigen Limited |
Peptide boronic acid inhibitors
|
EP1561466A3
(de)
*
|
2002-09-09 |
2006-08-23 |
Trigen Limited |
Borsäuresalze und deren Verwendung in der Bereitstellung von Medikamente für die Thrombosebehandlung
|
CN1684738A
(zh)
*
|
2002-09-20 |
2005-10-19 |
爱尔康公司 |
细胞因子合成抑制剂用于治疗干眼病的用途
|
ES2542328T3
(es)
|
2002-12-06 |
2015-08-04 |
Millennium Pharmaceuticals, Inc. |
Métodos para la identificación, evaluación y tratamiento de pacientes con terapia de inhibición del proteasoma
|
CN100341880C
(zh)
*
|
2003-02-13 |
2007-10-10 |
上海仁虎制药股份有限公司 |
新型硼酸或硼酸酯类化合物、制备方法及在药学上的应用
|
US20070110785A1
(en)
*
|
2003-07-03 |
2007-05-17 |
Eugene Tedeschi |
Medical devices with proteasome inhibitors for the treatment of restenosis
|
US7576206B2
(en)
*
|
2003-08-14 |
2009-08-18 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
US7223745B2
(en)
*
|
2003-08-14 |
2007-05-29 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
SG148161A1
(en)
|
2003-11-05 |
2008-12-31 |
Palingen Inc |
Enhanced b cell cytotoxicity of cdim binding antibody
|
US20060052390A1
(en)
*
|
2003-12-24 |
2006-03-09 |
Scios, Inc. |
Treatment of multiple myeloma by p38 MAP kinase and proteasome inhibition
|
CA2558106A1
(en)
*
|
2004-02-23 |
2005-09-09 |
Trustees Of Tufts College |
Inhibitors of dipeptidylpeptidase iv for regulating glucose metabolism
|
GB0405272D0
(en)
*
|
2004-03-09 |
2004-04-21 |
Trigen Ltd |
Compounds
|
US7371875B2
(en)
*
|
2004-03-12 |
2008-05-13 |
Miikana Therapeutics, Inc. |
Cytotoxic agents and methods of use
|
DK2377869T3
(da)
*
|
2004-03-30 |
2014-04-14 |
Millennium Pharm Inc |
Syntese af Bortezomib
|
AU2016202747B2
(en)
*
|
2004-03-30 |
2017-11-23 |
Millennium Pharmaceuticals, Inc. |
Synthesis of boronic ester and acid compounds
|
US8198270B2
(en)
|
2004-04-15 |
2012-06-12 |
Onyx Therapeutics, Inc. |
Compounds for proteasome enzyme inhibition
|
CN103554222A
(zh)
|
2004-04-15 |
2014-02-05 |
欧尼斯治疗公司 |
用于抑制蛋白酶体酶的化合物
|
CN102875642A
(zh)
|
2004-05-10 |
2013-01-16 |
普罗特奥里克斯公司 |
用于酶抑制的化合物
|
WO2006002422A2
(en)
|
2004-06-24 |
2006-01-05 |
Novartis Vaccines And Diagnostics Inc. |
Compounds for immunopotentiation
|
EP1794120B1
(de)
|
2004-07-23 |
2012-04-11 |
Nuada, LLC |
Peptidaseinhibitoren
|
AU2005266312C1
(en)
*
|
2004-07-28 |
2011-06-16 |
Janssen Pharmaceutica N.V. |
Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase
|
CA2584515A1
(en)
|
2004-10-20 |
2006-04-27 |
Proteolix, Inc. |
Labeled compounds for proteasome inhibition
|
EP1814913B1
(de)
|
2004-11-05 |
2015-08-19 |
IGM Biosciences, Inc. |
Antikörperinduzierte zellmembranverletzung
|
TW200618820A
(en)
*
|
2004-11-05 |
2006-06-16 |
Alza Corp |
Liposome formulations of boronic acid compounds
|
US8017395B2
(en)
|
2004-12-17 |
2011-09-13 |
Lifescan, Inc. |
Seeding cells on porous supports
|
US20070098685A1
(en)
*
|
2005-01-19 |
2007-05-03 |
Brand Stephen J |
Methods and kits to treat chronic inflammatory immune diseases by administering a proteasome inhibitor and an interleukin 2 receptor agonist
|
AU2006207325B2
(en)
|
2005-01-21 |
2012-08-16 |
Astex Therapeutics Limited |
Pharmaceutical compounds
|
CA2595749A1
(en)
*
|
2005-01-27 |
2006-08-03 |
Research Development Foundation |
Combination therapy with triterpenoid compounds and proteasome inhibitors
|
US7468383B2
(en)
*
|
2005-02-11 |
2008-12-23 |
Cephalon, Inc. |
Proteasome inhibitors and methods of using the same
|
JP5038912B2
(ja)
|
2005-02-16 |
2012-10-03 |
アナコール ファーマシューティカルズ,インコーポレイテッド |
ホウ素含有小分子
|
US7589066B2
(en)
*
|
2005-03-11 |
2009-09-15 |
The University Of North Carolina At Chapel Hill |
Potent and specific immunoproteasome inhibitors
|
AU2006242446A1
(en)
*
|
2005-04-29 |
2006-11-09 |
Kosan Biosciences Incorporated |
Method of treating multiple myeloma using 17-AAG or 17-AG or a prodrug of either in combination with a proteasome inhibitor
|
DK1885710T3
(en)
|
2005-05-18 |
2015-11-23 |
Janssen Pharmaceutica Nv |
SUBSTITUTED AMINOPROPENYLPIPERIDINE OR MORPHOLINE DERIVATIVES AS UNKNOWN INHIBITORS OF HISTONDEACETYLASE
|
AU2006202209B2
(en)
*
|
2005-05-27 |
2011-04-14 |
Lifescan, Inc. |
Amniotic fluid derived cells
|
CN101484575B
(zh)
*
|
2005-06-08 |
2013-10-02 |
森托科尔公司 |
用于眼变性的细胞疗法
|
EP1912664A2
(de)
*
|
2005-07-06 |
2008-04-23 |
Biodevelops Pharma Entwicklung GmbH |
Verwendung einer verbindung zur verstärkung der expression von membranproteinen auf der zelloberfläche
|
EP1752467A1
(de)
|
2005-08-10 |
2007-02-14 |
4Sc Ag |
Krebszellen-, t-Zellen- und Keratinocyte-Proliferation-Inhibitoren
|
US7531517B2
(en)
|
2005-08-10 |
2009-05-12 |
4Sc Ag |
Inhibitors of cancer cell, T-cell and keratinocyte proliferation
|
US20070059382A1
(en)
*
|
2005-09-09 |
2007-03-15 |
Board Of Regents, Univ. And Comm. College System Of Nevada... |
Medical treatment of breast cancer with boric acid materials
|
DK2623113T3
(en)
|
2005-11-09 |
2017-07-17 |
Onyx Therapeutics Inc |
Enzyme inhibition compound
|
WO2007067752A2
(en)
*
|
2005-12-08 |
2007-06-14 |
Cytokinetics, Inc. |
Certain compositions and methods of treatment
|
CN106008583A
(zh)
|
2005-12-30 |
2016-10-12 |
安纳考尔医药公司 |
含硼的小分子
|
EP1979326B1
(de)
|
2006-01-19 |
2012-10-03 |
Janssen Pharmaceutica N.V. |
Pyridin- und pyrimidinderivate als inhibitoren von histondeacetylase
|
US8101616B2
(en)
*
|
2006-01-19 |
2012-01-24 |
Janssen Pharmaceutica N.V. |
Pyridine and pyrimidine derivatives as inhibitors of histone deacetylase
|
PL1981874T3
(pl)
*
|
2006-01-19 |
2009-10-30 |
Janssen Pharmaceutica Nv |
Pochodne aminofenylowe jako nowe inhibitory deacetylazy histonowej
|
AU2007206950B2
(en)
*
|
2006-01-19 |
2012-02-02 |
Janssen Pharmaceutica N.V. |
Substituted indolyl-alkyl-amino-derivatives as inhibitors of histone deacetylase
|
JO2660B1
(en)
|
2006-01-20 |
2012-06-17 |
نوفارتيس ايه جي |
Pi-3 inhibitors and methods of use
|
PE20070978A1
(es)
*
|
2006-02-14 |
2007-11-15 |
Novartis Ag |
COMPUESTOS HETEROCICLICOS COMO INHIBIDORES DE FOSFATIDILINOSITOL 3-QUINASAS (PI3Ks)
|
PT2719388T
(pt)
|
2006-02-16 |
2019-06-11 |
Anacor Pharmaceuticals Inc |
Moléculas pequenas que contêm boro como agentes antiinflamatórios
|
AR060358A1
(es)
*
|
2006-04-06 |
2008-06-11 |
Novartis Vaccines & Diagnostic |
Quinazolinas para la inhibicion de pdk 1
|
US8741643B2
(en)
|
2006-04-28 |
2014-06-03 |
Lifescan, Inc. |
Differentiation of pluripotent stem cells to definitive endoderm lineage
|
DE102006026464A1
(de)
|
2006-06-01 |
2007-12-06 |
Virologik Gmbh Innovationszentrum Medizintechnik Und Pharma |
Pharmazeutische Zusammensetzung zur Behandlung von Virusinfektionen und / oder Tumorerkrankungen durch Inhibition der Proteinfaltung und des Proteinabbaus
|
WO2007143600A2
(en)
*
|
2006-06-05 |
2007-12-13 |
Incyte Corporation |
Sheddase inhibitors combined with cd30-binding immunotherapeutics for the treatment of cd30 positive diseases
|
PT2041158E
(pt)
|
2006-06-19 |
2013-07-17 |
Onyx Therapeutics Inc |
Péptido epoxicetonas para inibição de proteassoma
|
WO2008031817A2
(en)
*
|
2006-09-15 |
2008-03-20 |
Janssen Pharmaceutica Nv |
Histone deacetylase inhibitors with combined activity on class-i and class-iib histone deacetylases in combination with proteasome inhibitors
|
EP2066328A2
(de)
*
|
2006-09-15 |
2009-06-10 |
Janssen Pharmaceutica N.V. |
Kombinationen aus klasse-1-spezifischen histon-deacetylasehemmern mit proteasomhemmern
|
US8883790B2
(en)
|
2006-10-12 |
2014-11-11 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
US8916552B2
(en)
|
2006-10-12 |
2014-12-23 |
Astex Therapeutics Limited |
Pharmaceutical combinations
|
CA2606634A1
(en)
*
|
2006-12-08 |
2008-06-08 |
Centenary Institute Of Cancer Medicine And Cell Biology |
Assay for response to proteasome inhibitors
|
JO3396B1
(ar)
|
2007-06-20 |
2019-10-20 |
Anacor Pharmaceuticals Inc |
جزيئات صغيرة تحتوي على البورون
|
US9080145B2
(en)
|
2007-07-01 |
2015-07-14 |
Lifescan Corporation |
Single pluripotent stem cell culture
|
DK2185693T3
(da)
|
2007-07-31 |
2019-09-23 |
Lifescan Inc |
Differentiering af humane embryoniske stamceller
|
CA2685540C
(en)
|
2007-08-03 |
2018-10-16 |
Graham Michael Wynne |
Drug combinations for the treatment of duchenne muscular dystrophy
|
GB0715087D0
(en)
|
2007-08-03 |
2007-09-12 |
Summit Corp Plc |
Drug combinations for the treatment of duchenne muscular dystrophy
|
UA97536C2
(en)
*
|
2007-08-06 |
2012-02-27 |
Милленниум Фармасьютикалз, Инк. |
Proteasome inhibitors
|
US7442830B1
(en)
|
2007-08-06 |
2008-10-28 |
Millenium Pharmaceuticals, Inc. |
Proteasome inhibitors
|
EA034601B1
(ru)
*
|
2007-08-06 |
2020-02-25 |
Милленниум Фармасьютикалз, Инк. |
Способ получения бороновых кислот
|
AU2016253697A1
(en)
*
|
2007-08-06 |
2016-11-24 |
Millennium Pharmaceuticals, Inc. |
Proteasome inhibitors
|
AU2008298694A1
(en)
*
|
2007-09-12 |
2009-03-19 |
Dr. Reddy's Laboratories Ltd. |
Bortezomib and process for producing same
|
US20090076031A1
(en)
*
|
2007-09-17 |
2009-03-19 |
Protia, Llc |
Deuterium-enriched bortezomib
|
AU2008307510A1
(en)
|
2007-10-04 |
2009-04-09 |
Onyx Therapeutics, Inc. |
Crystalline peptide epoxy ketone protease inhibitors and the synthesis of amino acid keto-epoxides
|
US7838673B2
(en)
*
|
2007-10-16 |
2010-11-23 |
Millennium Pharmaceuticals, Inc. |
Proteasome inhibitors
|
US20090110688A1
(en)
*
|
2007-10-24 |
2009-04-30 |
Georg Fertig |
Combination therapy of type ii anti-cd20 antibody with a proteasome inhibitor
|
JP5710264B2
(ja)
*
|
2007-11-27 |
2015-04-30 |
ライフスキャン・インコーポレイテッドLifescan,Inc. |
ヒト胚性幹細胞の分化
|
CN101220048B
(zh)
*
|
2007-12-14 |
2012-08-15 |
江苏先声药物研究有限公司 |
ZnCl2催化下的蒎烷二醇酯的制备方法
|
US8940771B2
(en)
|
2007-12-20 |
2015-01-27 |
Novartis Ag |
Organic compounds
|
AU2009215516B2
(en)
|
2008-02-21 |
2014-12-18 |
Janssen Biotech Inc. |
Methods, surface modified plates and compositions for cell attachment, cultivation and detachment
|
KR101672511B1
(ko)
|
2008-03-06 |
2016-11-03 |
아나코르 파마슈티칼스 인코포레이티드 |
소염제로써 붕소가 함유된 소분자
|
EP2285384A4
(de)
*
|
2008-05-12 |
2012-04-25 |
Anacor Pharmaceuticals Inc |
Borhaltige kleine moleküle
|
RS54020B1
(en)
|
2008-06-17 |
2015-10-30 |
Millennium Pharmaceuticals Inc. |
ORGANOBOR ESTAR UNITS AND THEIR PHARMACEUTICAL COMPOSITIONS
|
AU2009267137A1
(en)
|
2008-06-30 |
2010-01-07 |
Centocor Ortho Biotech Inc. |
Differentiation of pluripotent stem cells
|
CN101638414B
(zh)
*
|
2008-07-30 |
2014-01-08 |
江苏先声药物研究有限公司 |
肽硼酸及其酯类化合物、制备方法及其用途
|
US20100028307A1
(en)
*
|
2008-07-31 |
2010-02-04 |
O'neil John J |
Pluripotent stem cell differentiation
|
US8461336B2
(en)
|
2008-09-04 |
2013-06-11 |
Anacor Pharmaceuticals, Inc. |
Boron-containing small molecules
|
WO2010027975A1
(en)
*
|
2008-09-04 |
2010-03-11 |
Anacor Pharmaceuticals, Inc. |
Boron-containing small molecules
|
AR075090A1
(es)
*
|
2008-09-29 |
2011-03-09 |
Millennium Pharm Inc |
Derivados de acido 1-amino-2-ciclobutiletilboronico inhibidores de proteosoma,utiles como agentes anticancerigenos, y composiciones farmaceuticas que los comprenden.
|
US9493489B2
(en)
*
|
2008-10-15 |
2016-11-15 |
Anacor Pharmaceuticals, Inc. |
Boron-containing small molecules as anti-protozoal agents
|
KR20110073584A
(ko)
|
2008-10-21 |
2011-06-29 |
오닉스 세라퓨틱스, 인크. |
펩티드 에폭시케톤과의 병용 요법
|
RU2528861C2
(ru)
*
|
2008-10-31 |
2014-09-20 |
Сентокор Орто Байотек Инк. |
Дифференцирование человеческих эмбриональных стволовых клеток в линию панкреатических эндокринных клеток
|
CA2742268C
(en)
|
2008-10-31 |
2020-02-18 |
Centocor Ortho Biotech Inc. |
Differentiation of human embryonic stem cells to the pancreatic endocrine lineage
|
PL2366022T3
(pl)
*
|
2008-11-20 |
2016-11-30 |
|
Sposoby i kompozycje do przyłączania i hodowli komórek na podłożach planarnych
|
ES2642070T3
(es)
|
2008-11-20 |
2017-11-15 |
Janssen Biotech, Inc. |
Cultivo de células madre pluripotentes en microportadores
|
CN101747354B
(zh)
*
|
2008-12-04 |
2014-08-13 |
江苏先声药物研究有限公司 |
一类β氨基酸组成的二肽硼酸及其酯类化合物、制备方法及其用途
|
AU2009335744A1
(en)
*
|
2008-12-17 |
2010-07-15 |
Anacor Pharmaceuticals, Inc. |
Polymorphs of (S)-3-aminomethyl-7-(3-hydroxy-propoxy) -3H-benzo[c][1,2] oxaborol-1-ol
|
JP5689816B2
(ja)
|
2009-01-09 |
2015-03-25 |
サン・ファーマ・アドバンスド・リサーチ・カンパニー・リミテッド |
非経口用医薬組成物及びその非経口用医薬組成物の製造方法
|
EP3021120A1
(de)
|
2009-02-20 |
2016-05-18 |
Michael P. Lisanti |
Verfahren zur diagnose oder prognose eines neoplasmas einschliesslich der bestimmung des expressionsgrads eines proteins in stromazellen neben dem neoplasma
|
JP5709766B2
(ja)
|
2009-03-12 |
2015-04-30 |
ジェネンテック, インコーポレイテッド |
造血器腫瘍の治療のためのホスホイノシチド3キナーゼ阻害剤化合物と化学療法剤の併用
|
WO2010106135A1
(en)
|
2009-03-20 |
2010-09-23 |
Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. |
Combined use for the treatment of ovarian carcinoma
|
AR075899A1
(es)
|
2009-03-20 |
2011-05-04 |
Onyx Therapeutics Inc |
Tripeptidos epoxicetonas cristalinos inhibidores de proteasa
|
CA2756193A1
(en)
|
2009-03-24 |
2010-09-30 |
Janssen Pharmaceutica Nv |
Biomarkers for assessing peripheral neuropathy response to treatment with a proteasome inhibitor
|
CA2756072A1
(en)
*
|
2009-03-30 |
2010-10-14 |
Cerulean Pharma Inc. |
Polymer-agent conjugates, particles, compositions, and related methods of use
|
WO2010114770A1
(en)
*
|
2009-03-30 |
2010-10-07 |
Cerulean Pharma Inc. |
Polymer-agent conjugates, particles, compositions, and related methods of use
|
WO2010114768A1
(en)
*
|
2009-03-30 |
2010-10-07 |
Cerulean Pharma Inc. |
Polymer-epothilone conjugates, particles, compositions, and related methods of use
|
MX2011012538A
(es)
*
|
2009-05-27 |
2012-02-08 |
Cephalon Inc |
Terapia de combinacion para el tratamiento del mieloma multiple.
|
EP2280016A1
(de)
|
2009-07-27 |
2011-02-02 |
LEK Pharmaceuticals d.d. |
Neue synthetische Route zur Herstellung von Alpha-Aminoborestern über substituierte Alylene
|
EP2270019A1
(de)
|
2009-06-19 |
2011-01-05 |
LEK Pharmaceuticals d.d. |
Neue synthetische Route zur Herstellung von alpha-Aminoborestern
|
EP2443128B1
(de)
|
2009-06-19 |
2017-12-20 |
LEK Pharmaceuticals d.d. |
Neue synthetische Route zur Herstellung von alpha-Aminoboronsäure-estern
|
CN101928329B
(zh)
*
|
2009-06-19 |
2013-07-17 |
北京大学 |
三肽硼酸(酯)类化合物、其制备方法和应用
|
US8293753B2
(en)
|
2009-07-02 |
2012-10-23 |
Novartis Ag |
Substituted 2-carboxamide cycloamino ureas
|
DE102009027754A1
(de)
|
2009-07-15 |
2011-05-05 |
Schubert, Ulrich, Dr. |
Verfahren zur Hemmung der Reifung von dendritischen Zellen
|
JP6219568B2
(ja)
|
2009-07-20 |
2017-10-25 |
ヤンセン バイオテツク,インコーポレーテツド |
ヒト胚性幹細胞の分化
|
ES2693088T3
(es)
*
|
2009-07-20 |
2018-12-07 |
Janssen Biotech, Inc. |
Diferenciación de células madre embriónicas humanas
|
AR077766A1
(es)
|
2009-07-20 |
2011-09-21 |
Janssen Biotech Inc |
Diferenciacion de celulas madre embrionarias humanas
|
BR112012001987A2
(pt)
*
|
2009-07-28 |
2015-09-01 |
Anacor Pharmaceuticals Inc |
Composto, combinação, formulação farmacêutica, uso de um composto, uma combinação ou um sal farmaceuticamente aceitável dos mesmos, e, métodos para tratar uma infecção bacteriana, para matar ou inibir o crescimento de uma bactéria, e para inibir uma beta-lactamase.
|
AP4039A
(en)
*
|
2009-08-14 |
2017-02-28 |
Daitao Chen |
Boron-containing small molecules as antiprotozoal agents
|
US20120149663A1
(en)
|
2009-08-18 |
2012-06-14 |
Georgetown University |
Boronic acid compositions and methods related to cancer
|
US20110207701A1
(en)
*
|
2009-08-19 |
2011-08-25 |
Anacor Pharmaceuticals, Inc. |
Boron-containing small molecules as antiprotozoal agents
|
CA2770252C
(en)
|
2009-09-08 |
2018-06-12 |
F. Hoffmann-La Roche Ag |
4-substituted pyridin-3-yl-carboxamide compounds and uses thereof for treating cancer
|
WO2011037731A1
(en)
*
|
2009-09-25 |
2011-03-31 |
Anacor Pharmaceuticals, Inc. |
Boron containing small molecules
|
EP2305285A1
(de)
|
2009-09-29 |
2011-04-06 |
Julius-Maximilians-Universität Würzburg |
Mittel und Verfahren zur Behandlung von ischämischen Erkrankungen
|
EP2519231B1
(de)
|
2009-10-01 |
2017-03-15 |
Janssen Pharmaceutica NV |
Behandlung von erkrankungen mit proteasomhemmern
|
WO2011049971A1
(en)
|
2009-10-20 |
2011-04-28 |
Anacor Pharmaceuticals, Inc. |
Boron-containing small molecules as antiprotozoal agents
|
WO2011060199A1
(en)
*
|
2009-11-11 |
2011-05-19 |
Anacor Pharmaceuticals, Inc. |
Boron-containing small molecules
|
JP5919196B2
(ja)
|
2009-11-13 |
2016-05-18 |
オニキス セラピューティクス, インク.Onyx Therapeutics, Inc. |
転移抑制のためのペプチドエポキシケトンの使用
|
MX2012007341A
(es)
|
2009-12-22 |
2012-07-20 |
Cephalon Inc |
Inhibidores de proteasoma y procesos para su preparacion, purificacion y uso.
|
CN102741395B
(zh)
|
2009-12-23 |
2016-03-16 |
詹森生物科技公司 |
人胚胎干细胞的分化
|
CN102712902B
(zh)
|
2009-12-23 |
2019-01-08 |
詹森生物科技公司 |
人胚胎干细胞的分化
|
US20110178287A1
(en)
|
2010-01-19 |
2011-07-21 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
WO2011094450A1
(en)
|
2010-01-27 |
2011-08-04 |
Anacor Pharmaceuticals, Inc |
Boron-containing small molecules
|
MX2012010017A
(es)
*
|
2010-03-01 |
2012-10-01 |
Onyx Therapeutics Inc |
Compuestos de para la inhibicion de inmunoproteasomas.
|
WO2011109279A2
(en)
*
|
2010-03-01 |
2011-09-09 |
Centocor Ortho Biotech Inc. |
Methods for purifying cells derived from pluripotent stem cells
|
US8263578B2
(en)
|
2010-03-18 |
2012-09-11 |
Innopharma, Inc. |
Stable bortezomib formulations
|
US9061037B2
(en)
*
|
2010-03-18 |
2015-06-23 |
Innopharma, Inc. |
Stable bortezomib formulations
|
AP2012006482A0
(en)
|
2010-03-19 |
2012-10-31 |
Anacor Pharmacueticals Inc |
Boron-containing small molecules as anti-protozoalagent
|
EP2550362B1
(de)
|
2010-03-25 |
2017-01-04 |
Oregon Health&Science University |
Cmv-glycoproteine und rekombinante vektoren
|
KR20130036228A
(ko)
*
|
2010-03-31 |
2013-04-11 |
밀레니엄 파머슈티컬스 인코퍼레이티드 |
1-아미노-2-사이클로프로필에틸보론산의 유도체
|
AU2013204868B2
(en)
*
|
2010-03-31 |
2016-10-13 |
Millennium Pharmaceuticals, Inc. |
Derivatives of 1-amino-2-cyclopropylethylboronic acid
|
US8697646B2
(en)
|
2010-04-07 |
2014-04-15 |
Onyx Therapeutics, Inc. |
Crystalline peptide epoxyketone immunoproteasome inhibitor
|
CN101812026B
(zh)
*
|
2010-04-12 |
2013-08-28 |
亚邦医药股份有限公司 |
一种硼替佐米的合成方法
|
CN102946879B
(zh)
|
2010-04-19 |
2015-04-22 |
尼基制药公司 |
一种蛋白酶体抑制剂和镓络合物在制备治疗增殖性疾病的药物中的应用
|
US8809282B2
(en)
|
2010-05-06 |
2014-08-19 |
Duke University |
Method of reducing titers of antibodies specific for a therapeutic agent
|
SG10201503652WA
(en)
|
2010-05-12 |
2015-08-28 |
Janssen Biotech Inc |
Differentiation of human embryonic stem cells
|
CA2799202C
(en)
|
2010-05-18 |
2016-07-05 |
Cerulean Pharma Inc. |
Compositions and methods for treatment of autoimmune and other diseases
|
AR082418A1
(es)
|
2010-08-02 |
2012-12-05 |
Novartis Ag |
Formas cristalinas de 1-(4-metil-5-[2-(2,2,2-trifluoro-1,1-dimetil-etil)-piridin-4-il]-tiazol-2-il)-amida de 2-amida del acido (s)-pirrolidin-1,2-dicarboxilico
|
EP3372672A1
(de)
|
2010-08-31 |
2018-09-12 |
Janssen Biotech, Inc. |
Differenzierung menschlicher embryonischer stammzellen
|
CN108517310B
(zh)
|
2010-08-31 |
2022-02-15 |
詹森生物科技公司 |
人胚胎干细胞的分化
|
SG187947A1
(en)
|
2010-08-31 |
2013-03-28 |
Janssen Biotech Inc |
Differentiation of pluripotent stem cells
|
US9126997B1
(en)
|
2010-09-07 |
2015-09-08 |
Northwestern University |
Synergistic effect of glucocorticoid receptor agonists in combination with proteosome inhibitors for treating leukemia and myeloma
|
HRP20211762T1
(hr)
|
2010-09-07 |
2022-02-18 |
Anacor Pharmaceuticals, Inc. |
Derivati benzoksaborola za liječenje bakterijskih infekcija
|
EP2624818B1
(de)
|
2010-10-05 |
2017-04-05 |
Fresenius Kabi USA, LLC |
Mit borsäure stabilisierte bortezomib-formulierungen
|
US8884009B2
(en)
|
2010-10-14 |
2014-11-11 |
Synthon Bv |
Process for making bortezomib and intermediates for the process
|
AU2012213080B2
(en)
|
2011-01-31 |
2014-03-27 |
Novartis Ag |
Novel heterocyclic derivatives
|
TW201309303A
(zh)
*
|
2011-03-03 |
2013-03-01 |
Cephalon Inc |
用於治療狼瘡的蛋白酶體抑制劑
|
WO2012135528A2
(en)
|
2011-03-29 |
2012-10-04 |
Texas Tech University System |
Galectin-3c combination therapy for human cancer
|
WO2012133884A1
(ja)
|
2011-03-31 |
2012-10-04 |
ナノキャリア株式会社 |
ボロン酸化合物を含有したブロック共重合体を含む医薬組成物
|
CA2832109C
(en)
|
2011-06-10 |
2021-07-06 |
Oregon Health & Science University |
Cmv glycoproteins and recombinant vectors
|
MX2013015308A
(es)
*
|
2011-06-22 |
2014-05-20 |
Cephalon Inc |
Inhibidores de proteasoma y procesos para su preparacion, purificacion y uso.
|
US8481655B2
(en)
|
2011-07-27 |
2013-07-09 |
Wacker Chemical Corporation |
Copper complexes of amino-functional organosilicon compounds and their use
|
RS55053B1
(sr)
|
2011-08-11 |
2016-12-30 |
Janssen Pharmaceutica Nv |
Prediktori za lečenje kancera
|
WO2013021032A1
(en)
|
2011-08-11 |
2013-02-14 |
Janssen Pharmaceutica Nv |
Histone deacetylase inhibitors in combination with proteasome inhibitors and dexamethasone
|
SG10201606883QA
(en)
|
2011-08-19 |
2016-10-28 |
Glaxo Group Ltd |
Benzofuran compounds for the treatment of hepatitis c virus infections
|
ES2929179T3
(es)
*
|
2011-08-30 |
2022-11-25 |
Tufts College |
Inhibidores del proteasoma activados por FAP para el tratamiento de tumores sólidos
|
AU2012216792A1
(en)
|
2011-09-12 |
2013-03-28 |
International Aids Vaccine Initiative |
Immunoselection of recombinant vesicular stomatitis virus expressing HIV-1 proteins by broadly neutralizing antibodies
|
US9402894B2
(en)
|
2011-10-27 |
2016-08-02 |
International Aids Vaccine Initiative |
Viral particles derived from an enveloped virus
|
ES2776144T3
(es)
|
2011-10-28 |
2020-07-29 |
Millennium Pharm Inc |
Biomarcadores de respuesta a inhibidores de NAE
|
CN104039790B
(zh)
|
2011-10-28 |
2016-04-13 |
诺华股份有限公司 |
嘌呤衍生物及它们在治疗疾病中的应用
|
JP6286358B2
(ja)
|
2011-11-11 |
2018-02-28 |
ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. |
プロテアソーム阻害剤に応答するバイオマーカー
|
EP2776043B1
(de)
|
2011-11-11 |
2018-02-21 |
Millennium Pharmaceuticals, Inc. |
Biomarker der reaktion auf proteasomenhemmer
|
JP5481614B2
(ja)
|
2011-11-17 |
2014-04-23 |
国立大学法人 東京大学 |
フェニルボロン酸基が導入されたブロックコポリマーおよびその使用
|
AU2012355698B2
(en)
|
2011-12-22 |
2018-11-29 |
Janssen Biotech, Inc. |
Differentiation of human embryonic stem cells into single hormonal insulin positive cells
|
US9732101B2
(en)
|
2012-01-18 |
2017-08-15 |
Wisconsin Alumni Research Foundation |
Bioreversible boronates for delivery of molecules into cells
|
US9234048B2
(en)
|
2012-01-18 |
2016-01-12 |
Wisconsin Alumni Research Foundation |
Boronate-mediated delivery of molecules into cells
|
CA2862492A1
(en)
|
2012-01-24 |
2013-08-01 |
Millennium Pharmaceuticals, Inc. |
Methods of treatment of cancer
|
GB2523211B
(en)
|
2012-01-27 |
2020-03-18 |
Univ Jefferson |
MCT protein inhibitor-related prognostic and therapeutic methods
|
MX363819B
(es)
|
2012-02-08 |
2019-04-03 |
Igm Biosciences Inc |
Uniones a cdim y sus usos.
|
CA2866135A1
(en)
|
2012-03-02 |
2014-09-06 |
Dr. Reddy's Laboratories Limited |
Pharmaceutical compositions comprising boronic acid compounds
|
RU2018128383A
(ru)
|
2012-03-07 |
2019-03-14 |
Янссен Байотек, Инк. |
Среда определенного состава для размножения и обновления плюрипотентных стволовых клеток
|
CA2784240C
(en)
|
2012-03-27 |
2014-07-08 |
Innopharma, Inc. |
Stable bortezomib formulations
|
SG11201406550QA
(en)
|
2012-05-16 |
2014-11-27 |
Novartis Ag |
Dosage regimen for a pi-3 kinase inhibitor
|
EP3450543A1
(de)
|
2012-06-08 |
2019-03-06 |
Janssen Biotech, Inc. |
Differenzierung humaner embryonaler stammzellen in endokrine pankreaszellen
|
ES2631608T3
(es)
|
2012-06-27 |
2017-09-01 |
International Aids Vaccine Initiative |
Variante de la glicoproteína Env del VIH-1
|
US20140105921A1
(en)
|
2012-07-09 |
2014-04-17 |
Onyx Therapeutics, Inc. |
Prodrugs of Peptide Epoxy Ketone Protease Inhibitors
|
JP2013006855A
(ja)
*
|
2012-09-03 |
2013-01-10 |
Millennium Pharmaceuticals Inc |
プロテアソーム阻害剤
|
JP2015532915A
(ja)
*
|
2012-09-11 |
2015-11-16 |
シプラ・リミテッド |
ボルテゾミブの製造方法
|
JP6486826B2
(ja)
|
2012-10-01 |
2019-03-20 |
ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. |
阻害剤に対する応答を予測するためのバイオマーカーおよび方法、ならびにそれらの使用
|
WO2014072985A1
(en)
|
2012-11-06 |
2014-05-15 |
Natco Pharma Limited |
Novel boronic acid derivatives as anti cancer agents
|
NZ630287A
(en)
|
2012-11-16 |
2016-07-29 |
Shilpa Medicare Ltd |
Crystalline bortezomib process
|
WO2014097306A1
(en)
|
2012-12-21 |
2014-06-26 |
Natco Pharma Limited |
Stable and pure polymorphic form of bortezomib
|
US10370644B2
(en)
|
2012-12-31 |
2019-08-06 |
Janssen Biotech, Inc. |
Method for making human pluripotent suspension cultures and cells derived therefrom
|
RU2658488C2
(ru)
|
2012-12-31 |
2018-06-21 |
Янссен Байотек, Инк. |
Способ получения клеток, экспрессирующих маркеры, характерные для панкреатических эндокринных клеток
|
ES2906998T3
(es)
|
2012-12-31 |
2022-04-21 |
Janssen Biotech Inc |
Suspensión y agrupación de células pluripotentes humanas para su diferenciación en células endocrinas pancreáticas
|
CA2896658C
(en)
|
2012-12-31 |
2021-06-22 |
Janssen Biotech, Inc. |
Differentiation of human embryonic stem cells into pancreatic endocrine cells using hb9 regulators
|
CN112521369A
(zh)
|
2013-03-13 |
2021-03-19 |
福马治疗股份有限公司 |
用于抑制fasn的化合物及组合物
|
EP2986619A1
(de)
|
2013-04-16 |
2016-02-24 |
Cipla Limited |
Verfahren zur herstellung von bortezomib-mannitol-ester
|
US10022372B2
(en)
|
2013-04-19 |
2018-07-17 |
Thomas Jefferson University |
Caveolin-1 related methods for treating glioblastoma with temozolomide
|
US9603775B2
(en)
|
2013-04-24 |
2017-03-28 |
Corning Incorporated |
Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients
|
WO2015003146A1
(en)
|
2013-07-03 |
2015-01-08 |
Georgetown University |
Boronic acid derivatives of resveratrol for activating deacetylase enzymes
|
US20150065381A1
(en)
|
2013-09-05 |
2015-03-05 |
International Aids Vaccine Initiative |
Methods of identifying novel hiv-1 immunogens
|
EP3052105A1
(de)
|
2013-10-03 |
2016-08-10 |
Millennium Pharmaceuticals, Inc. |
Verfahren zur prophylaxe oder behandlung von systemischem lupus erythematosus und/oder lupus nephritis
|
US10058604B2
(en)
|
2013-10-07 |
2018-08-28 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
CN104586776B
(zh)
*
|
2013-10-30 |
2017-05-17 |
扬子江药业集团上海海尼药业有限公司 |
以硼替佐米为活性成分的制剂及其制备方法
|
JP6468562B2
(ja)
*
|
2013-11-21 |
2019-02-13 |
国立大学法人北海道大学 |
プロテアソーム阻害性化合物
|
US10191033B2
(en)
|
2013-12-05 |
2019-01-29 |
The Broad Institute, Inc. |
Biomarkers for detecting pre-cachexia or cachexia and methods of treatment thereof
|
DK3076969T3
(da)
|
2013-12-06 |
2021-11-22 |
Novartis Ag |
Doseringsregime for en alfa-isoform-selektiv phosphatidylinositol-3-kinase-hæmmer
|
CN106132970B
(zh)
|
2014-02-03 |
2020-09-04 |
俄亥俄州创新基金会 |
硼酸酯和其药物制剂
|
EP2910557A1
(de)
*
|
2014-02-20 |
2015-08-26 |
Ikerchem, S.L. |
Enantiomerenreine tetrasubstituierte Pyrrolidine als Gerüste für Proteasomhemmer und medizinische Anwendungen davon
|
JP6566936B2
(ja)
|
2014-05-08 |
2019-08-28 |
国立大学法人 東京大学 |
医薬組成物
|
WO2015175307A1
(en)
|
2014-05-16 |
2015-11-19 |
Janssen Biotech, Inc. |
Use of small molecules to enhance mafa expression in pancreatic endocrine cells
|
UA121389C2
(uk)
|
2014-05-20 |
2020-05-25 |
Мілленніум Фармасьютікалз, Інк. |
Борвмісні інгібітори протеасом для застосування після первинної протиракової терапії
|
EP4180041A1
(de)
|
2014-08-07 |
2023-05-17 |
Mayo Foundation for Medical Education and Research |
Verbindungen und verfahren zur behandlung von krebs
|
BR112017006349A2
(pt)
*
|
2014-10-01 |
2017-12-12 |
Merck Patent Gmbh |
derivados de ácido borônico
|
WO2016110870A1
(en)
|
2015-01-07 |
2016-07-14 |
Emcure Pharmaceuticals Limited |
Pharmaceutical composition of bortezomid
|
MA41505A
(fr)
|
2015-02-11 |
2017-12-19 |
Millennium Pharm Inc |
Nouvelle forme cristalline d'un inhibiteur de protéasome
|
EP3270891A1
(de)
|
2015-03-17 |
2018-01-24 |
Leon-Nanodrugs GmbH |
Nanopartikel mit einer stabilisierten boronsäureverbindung
|
US10174292B2
(en)
|
2015-03-20 |
2019-01-08 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
US9931394B2
(en)
|
2015-03-23 |
2018-04-03 |
International Aids Vaccine Initiative |
Soluble HIV-1 envelope glycoprotein trimers
|
WO2016184793A1
(en)
|
2015-05-15 |
2016-11-24 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for treating a patient with vegfr inhibitor-resistant metastatic renal cell carcinoma
|
WO2016205790A2
(en)
|
2015-06-19 |
2016-12-22 |
Hanlin Scientific, Inc. |
Chiral specific boron-containing compounds and their use in treating cancer or amyloidosis
|
EP3120837A1
(de)
|
2015-07-22 |
2017-01-25 |
Stada Arzneimittel Ag |
Verfahren zur herstellung einer bortezomibester-lösung
|
CN106478700B
(zh)
*
|
2015-08-26 |
2020-12-29 |
杭州雷索药业有限公司 |
硼基取代的苯胺类蛋白激酶抑制剂
|
CN106588965A
(zh)
*
|
2015-10-15 |
2017-04-26 |
北京大学 |
脲拟肽硼酸化合物及其药物组合物、制备方法和用途
|
CA3002954A1
(en)
|
2015-11-02 |
2017-05-11 |
Novartis Ag |
Dosage regimen for a phosphatidylinositol 3-kinase inhibitor
|
EP3389715A4
(de)
|
2015-12-14 |
2019-06-12 |
David K. Thomas |
Zusammensetzungen und verfahren zur behandlung von kardialer dysfunktion
|
CN107151255A
(zh)
*
|
2016-03-06 |
2017-09-12 |
复旦大学 |
硼酸类化合物及其制备方法和用途
|
CN107151254A
(zh)
*
|
2016-03-06 |
2017-09-12 |
复旦大学 |
一种作为20s蛋白酶体抑制剂的硼酸类化合物及其制备方法
|
MA45479A
(fr)
|
2016-04-14 |
2019-02-20 |
Janssen Biotech Inc |
Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen
|
US11447506B2
(en)
|
2016-05-09 |
2022-09-20 |
Anacor Pharmaceuticals, Inc. |
Crystal forms of crisaborole in free form and preparation method and use thereof
|
CN106008572B
(zh)
*
|
2016-05-23 |
2018-08-17 |
成都千禧莱医药科技有限公司 |
一类二肽硼酸化合物及制备方法和用途
|
PT3472149T
(pt)
|
2016-06-21 |
2023-11-23 |
Orion Opthalmology Llc |
Derivados de prolinamida heterocíclicos
|
JP7164521B2
(ja)
|
2016-06-21 |
2022-11-01 |
オリオン・オフサルモロジー・エルエルシー |
炭素環式プロリンアミド誘導体
|
JP6681284B2
(ja)
*
|
2016-06-23 |
2020-04-15 |
信越化学工業株式会社 |
糖アルコール化合物の金属低減方法
|
JP6223508B2
(ja)
*
|
2016-06-27 |
2017-11-01 |
ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. |
プロテアソーム阻害剤
|
WO2018038687A1
(en)
|
2016-08-22 |
2018-03-01 |
Mustafa Nevzat Ilaç Sanayii A.Ş. |
Pharmaceutical formulations comprising a bortezomib-cyclodextrin complex
|
WO2018060833A1
(en)
|
2016-09-27 |
2018-04-05 |
Novartis Ag |
Dosage regimen for alpha-isoform selective phosphatidylinositol 3-kinase inhibitor alpelisib
|
CA3040820A1
(en)
|
2016-10-20 |
2018-04-26 |
Pfizer Inc. |
Therapeutic particles with peptide boronic acid or boronate ester compounds and methods of making and using same
|
US11584733B2
(en)
|
2017-01-09 |
2023-02-21 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
CA3049435A1
(en)
|
2017-01-09 |
2018-07-12 |
Scott Grindrod |
Selective histone deacetylase inhibitors for the treatment of human disease
|
EP3583110A1
(de)
|
2017-02-17 |
2019-12-25 |
Fresenius Kabi Oncology Ltd |
Verbessertes verfahren zur herstellung von boronsäureestern
|
EP3589659A4
(de)
|
2017-02-28 |
2021-03-24 |
Mayo Foundation for Medical Education and Research |
Verbindungen und verwendung zur behandlung von krebs
|
US20210128667A1
(en)
|
2017-08-23 |
2021-05-06 |
Kezar Life Sciences |
Immunoproteasome inhibitors and immunosuppressive agent in the treatment of autoimmune disorders
|
BR112020005079A2
(pt)
|
2017-09-14 |
2020-09-15 |
Glaxosmithkline Intellectual Property Development Limited |
tratamento de combinação para câncer
|
JP2018024694A
(ja)
*
|
2017-10-03 |
2018-02-15 |
ミレニアム ファーマシューティカルズ, インコーポレイテッドMillennium Pharmaceuticals, Inc. |
プロテアソーム阻害剤
|
SG11202003867SA
(en)
|
2017-11-16 |
2020-05-28 |
Principia Biopharma Inc |
Immunoproteasome inhibitors
|
MX2020005036A
(es)
*
|
2017-11-16 |
2020-08-17 |
Principia Biopharma Inc |
Inhibidores de inmunoproteasoma.
|
US10537585B2
(en)
|
2017-12-18 |
2020-01-21 |
Dexcel Pharma Technologies Ltd. |
Compositions comprising dexamethasone
|
US11407723B2
(en)
|
2018-01-09 |
2022-08-09 |
Shuttle Pharmaceuticals, Inc. |
Selective histone deacetylase inhibitors for the treatment of human disease
|
US20210106522A1
(en)
|
2018-01-29 |
2021-04-15 |
Cognos Therapeutics, Inc. |
Intratumoral delivery of bortezomib
|
TW202003553A
(zh)
|
2018-03-15 |
2020-01-16 |
美商艾伯維有限公司 |
用於治療癌症之abbv-621與抗癌劑之組合
|
US11243207B2
(en)
|
2018-03-29 |
2022-02-08 |
Mayo Foundation For Medical Education And Research |
Assessing and treating cancer
|
US10793554B2
(en)
|
2018-10-29 |
2020-10-06 |
Forma Therapeutics, Inc. |
Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone
|
CN109824756B
(zh)
*
|
2019-03-19 |
2022-03-22 |
山东大学 |
含有4-(苯磺酰基)哌嗪-2-酮的苯丙氨酸衍生物及其制备方法与应用
|
CN114437119A
(zh)
*
|
2020-10-30 |
2022-05-06 |
苏州开拓药业股份有限公司 |
一种c-Myc蛋白抑制剂及其制备方法和用途
|
WO2022120039A2
(en)
*
|
2020-12-02 |
2022-06-09 |
Steven Hoffman |
Compositions and methods for modulating cancer in non-human mammals
|
TW202237143A
(zh)
*
|
2020-12-10 |
2022-10-01 |
南韓商Lg化學股份有限公司 |
酸(Boronic Acid)化合物
|
US11964993B2
(en)
|
2021-07-03 |
2024-04-23 |
Shilpa Pharma Lifesciences Limited |
Crystalline bortezomib process
|
US20230062279A1
(en)
|
2021-08-12 |
2023-03-02 |
Extrovis Ag |
Pharmaceutical compositions of bortezomib
|
CN113957441B
(zh)
*
|
2021-10-29 |
2024-01-02 |
光华科学技术研究院(广东)有限公司 |
蚀刻液及其制备方法和应用
|
WO2023220641A2
(en)
|
2022-05-11 |
2023-11-16 |
Juno Therapeutics, Inc. |
Methods and uses related to t cell therapy and production of same
|
WO2023220655A1
(en)
|
2022-05-11 |
2023-11-16 |
Celgene Corporation |
Methods to overcome drug resistance by re-sensitizing cancer cells to treatment with a prior therapy via treatment with a t cell therapy
|