US1132581A
(en)
*
|
|
1915-03-23 |
Automobil Construktions Ges M B H Deutsche |
Method of operating combustion-engines.
|
US3980781A
(en)
*
|
1966-03-31 |
1976-09-14 |
Imperial Chemical Industries Limited |
Fungicidal composition and method containing 2-amino-pyrimidines
|
US4000138A
(en)
*
|
1966-03-31 |
1976-12-28 |
Imperial Chemical Industries Limited |
Organic compounds and compositions containing them
|
US4062950A
(en)
|
1973-09-22 |
1977-12-13 |
Bayer Aktiengesellschaft |
Amino sugar derivatives
|
US3914250A
(en)
|
1974-08-01 |
1975-10-21 |
American Home Prod |
1,4-Diazepino{8 6,5,4-jk{9 carbazoles
|
JPS608117B2
(ja)
|
1977-02-08 |
1985-02-28 |
財団法人微生物化学研究会 |
新生理活性物質エステラスチンおよびその製造法
|
DE2716677C2
(de)
|
1977-04-15 |
1985-10-10 |
Hoechst Ag, 6230 Frankfurt |
Cephemderivate und Verfahren zu ihrer Herstellung
|
DE2714880A1
(de)
|
1977-04-02 |
1978-10-26 |
Hoechst Ag |
Cephemderivate und verfahren zu ihrer herstellung
|
DE2719912C3
(de)
|
1977-05-04 |
1979-12-06 |
Bayer Ag, 5090 Leverkusen |
Verfahren zur Isolierung von 0- |4,6-Dideoxy-4- [JJl S-O,4,6/5)-4,5,6-trihydroxy-3-hydroxymethyl-2cyclohexen-1-yl] -amino] - a -D-glucopyranosyl} -(I Pfeil nach rechts 4)-0- a D-glucopyranosyl-(l Pfeil nach rechts 4)-D-glucopyranose aus Kulturbrühen
|
NO154918C
(no)
|
1977-08-27 |
1987-01-14 |
Bayer Ag |
Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
|
JPS5953920B2
(ja)
|
1977-12-28 |
1984-12-27 |
東洋醸造株式会社 |
新規なアミノ糖化合物およびその製法
|
CA1121290A
(en)
|
1978-02-14 |
1982-04-06 |
Yasuji Suhara |
Amino sugar derivatives
|
DE2928485A1
(de)
|
1979-07-14 |
1981-01-29 |
Bayer Ag |
Verwendung von harnstoffderivaten als arzneimittel bei der behandlung von fettstoffwechselstoerungen
|
ES505959A0
(es)
|
1980-10-09 |
1982-09-01 |
Hoechst Ag |
Procedimiento para la preparacion de un inactivador de alfa-amilasa
|
EP0056194B1
(en)
|
1981-01-05 |
1984-09-12 |
Takeda Chemical Industries, Ltd. |
N-substituted pseudo-aminosugars, their production and use
|
ZA821577B
(en)
|
1981-04-06 |
1983-03-30 |
Boots Co Plc |
Therapeutic agents
|
US4452813A
(en)
|
1981-05-22 |
1984-06-05 |
Taiho Pharmaceutical Company Limited |
Sulfonate derivatives, process for preparing same and antilipemic compositions containing the derivative
|
CA1247547A
(en)
|
1983-06-22 |
1988-12-28 |
Paul Hadvary |
Leucine derivatives
|
FI844289L
(fi)
|
1984-01-21 |
1985-07-22 |
Hoechst Ag |
Nya polypeptider med -amylashaemmande verkan, foerfarande foer deras framstaellning, deras anvaendning och farmaceutiska preparat.
|
US4713313A
(en)
|
1984-05-02 |
1987-12-15 |
Polaroid Corporation |
Photographic system and novel compounds
|
US4780126A
(en)
|
1984-08-30 |
1988-10-25 |
Bayer Aktiengesellschaft |
3-substituted 1-(2-halogenoalkoxy-benzenesulphonyl)-3-heteroaryl-(thio)ureas
|
US4634765A
(en)
|
1984-12-18 |
1987-01-06 |
Merrell Dow Pharmaceuticals Inc. |
Homodisaccharide hypoglycemic agents
|
FR2593178B1
(fr)
|
1986-01-20 |
1988-04-29 |
Esteve Labor Dr |
Derives de 2-benzimidazolylalkylthio (ou sulfinyle ou sulfonyle) leur preparation et leur application en tant que medicaments.
|
US4847271A
(en)
|
1986-01-27 |
1989-07-11 |
Merck & Co., Inc. |
Antihypercholesterolemic β-lactones
|
US4751237A
(en)
|
1986-01-27 |
1988-06-14 |
Merck & Co., Inc. |
Antihypercholesterolemic beta-lactones
|
DE3642824A1
(de)
|
1986-12-16 |
1988-06-30 |
Bayer Ag |
Substituierte 1-benzylsulfonyl-3-heteroaryl-(thio)harnstoffe
|
US4816477A
(en)
|
1987-05-26 |
1989-03-28 |
Merck & Co., Inc. |
Antihypercholesterolemic β-lactones
|
US4806564A
(en)
|
1987-05-26 |
1989-02-21 |
Merck & Co., Inc. |
Antihypercholesterolemic beta-lactones
|
IL86941A
(en)
|
1987-07-10 |
1993-07-08 |
Gist Brocades Nv |
Process for the preparation of cephem compounds and some new cephalosporin derivatives prepared by this process
|
DE3723327A1
(de)
|
1987-07-15 |
1989-02-02 |
Hoechst Ag |
Substituierte thienoimidazol-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische zubereitungen und ihre verwendung als magensaeuresekretionshemmer, magenschutzmittel sowie als medikament gegen intestinale entzuendungen
|
JPH01132581A
(ja)
*
|
1987-11-18 |
1989-05-25 |
Yoshitomi Pharmaceut Ind Ltd |
ピリミジン化合物
|
NZ227042A
(en)
|
1987-11-27 |
1991-05-28 |
Banyu Pharma Co Ltd |
Substituted alkylamine derivatives and pharmaceutical compositions
|
US5192772A
(en)
|
1987-12-09 |
1993-03-09 |
Nippon Shinyaku Co. Ltd. |
Therapeutic agents
|
JPH01216997A
(ja)
|
1988-02-24 |
1989-08-30 |
Fujisawa Pharmaceut Co Ltd |
新規セフェム化合物ならびにその製造法
|
EP0344383A1
(en)
|
1988-06-02 |
1989-12-06 |
Merrell Dow Pharmaceuticals Inc. |
Novel alpha-Glucosidase inhibitors
|
DE3836675A1
(de)
|
1988-10-28 |
1990-05-03 |
Hoechst Ag |
Glykosidase-inhibitor salbostatin, verfahren zu seiner herstellung und seine verwendung
|
IE61928B1
(en)
|
1988-11-29 |
1994-11-30 |
Boots Co Plc |
Treatment of obesity
|
JPH02169571A
(ja)
|
1988-12-22 |
1990-06-29 |
Banyu Pharmaceut Co Ltd |
置換アリルアミン誘導体
|
US5236917A
(en)
|
1989-05-04 |
1993-08-17 |
Sterling Winthrop Inc. |
Saccharin derivatives useful as proteolytic enzyme inhibitors and compositions and method of use thereof
|
US5064856A
(en)
|
1989-07-31 |
1991-11-12 |
Merck & Co., Inc. |
Novel hmg-coa synthase inhibitors
|
US5256675A
(en)
|
1989-08-07 |
1993-10-26 |
Fujisawa Pharmaceutical Co., Ltd. |
Thiazole derivatives, processes for production thereof and pharmaceutical compositions comprising the same
|
US4983597A
(en)
|
1989-08-31 |
1991-01-08 |
Merck & Co., Inc. |
Beta-lactams as anticholesterolemic agents
|
US5391571A
(en)
|
1989-11-15 |
1995-02-21 |
American Home Products Corporation |
Cholesterol ester hydrolase inhibitors
|
US5112820A
(en)
|
1990-03-05 |
1992-05-12 |
Sterling Drug Inc. |
Anti-glaucoma compositions containing 2- and 3-aminomethyl-6-arylcarbonyl- or 6-phenylthio-2,3-dihydropyrrolo-(1,2,3-de)-1,4-benzoxazines and method of use thereof
|
US5081122A
(en)
|
1990-03-05 |
1992-01-14 |
Sterling Drug Inc. |
Antiglaucoma compositions containing 4-arylcarbonyl-1-(4-morpholinyl)-lower-alkyl)-1H-indoles and method of use thereof
|
US4973587A
(en)
|
1990-03-08 |
1990-11-27 |
Sterling Drug Inc. |
3-arylcarbonyl-1-aminoalkyl-1H-indole-containing antiglaucoma method
|
US5013837A
(en)
|
1990-03-08 |
1991-05-07 |
Sterling Drug Inc. |
3-Arylcarbonyl-1H-indole-containing compounds
|
US5504078A
(en)
|
1990-06-08 |
1996-04-02 |
Merrell Dow Pharmaceuticals Inc. |
α-glucosidase inhibitors
|
US5120729A
(en)
|
1990-06-20 |
1992-06-09 |
Merck & Co., Inc. |
Beta-lactams as antihypercholesterolemics
|
FR2665159B1
(fr)
|
1990-07-24 |
1992-11-13 |
Rhone Poulenc Sante |
Nouveaux derives de la pyridine et de la quinoleine, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
US5217877A
(en)
|
1990-09-28 |
1993-06-08 |
Bristol-Myers Squibb Company |
Process for the preparation of α-glucosidase inhibitor, pradimicin Q
|
US5091418A
(en)
|
1990-09-28 |
1992-02-25 |
Bristol-Myers Squibb Company |
Novel alpha-glucosidase inhibitor, pradimicin Q
|
US5472967A
(en)
|
1991-02-20 |
1995-12-05 |
Synthelabo |
4-pyrimidinone derivatives their preparation and their application in therapy
|
US5182298A
(en)
|
1991-03-18 |
1993-01-26 |
Merck & Co., Inc. |
Cholesterol lowering agents
|
GB9105771D0
(en)
|
1991-03-19 |
1991-05-01 |
Cancer Res Inst Royal |
Anti-cancer compounds
|
IL101850A
(en)
|
1991-06-13 |
1996-01-31 |
Janssen Pharmaceutica Nv |
History 11-) 4-Pipridinyl (-Imidazo] B-1, 2 [] 3 [Benzazepine, their preparation and pharmaceutical preparations containing them
|
DE4243287A1
(de)
*
|
1992-06-19 |
1993-12-23 |
Basf Ag |
N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
|
FR2692575B1
(fr)
|
1992-06-23 |
1995-06-30 |
Sanofi Elf |
Nouveaux derives du pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
US5349056A
(en)
|
1992-10-09 |
1994-09-20 |
Regeneron Pharmaceuticals |
Modified ciliary neurotrophic factors
|
US6472178B1
(en)
|
1998-02-27 |
2002-10-29 |
Regeneron Pharmaceuticals, Inc. |
Nucleic acids encoding a modified ciliary neurotrophic factor and method of making thereof
|
JP3503064B2
(ja)
|
1992-12-04 |
2004-03-02 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノート シヤツプ |
抗アレルギー性イミダゾ[1,2,−a](ピロロ、チエノ又はフラノ)[2,3−d]アゼピン誘導体
|
JP3572074B2
(ja)
|
1992-12-04 |
2004-09-29 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
抗アレルギー性トリアゾロベンズアゼピン誘導体
|
KR100251296B1
(ko)
|
1992-12-04 |
2000-05-01 |
디르크 반테 |
항앨러지성 트리아졸로(피롤로, 티에노 또는 푸라노)아제핀 유도체(Antiallergic triazolo(pyrrolo, thieno or furano)azepine derivatives)
|
US5451677A
(en)
|
1993-02-09 |
1995-09-19 |
Merck & Co., Inc. |
Substituted phenyl sulfonamides as selective β 3 agonists for the treatment of diabetes and obesity
|
US5292736A
(en)
|
1993-02-26 |
1994-03-08 |
Sterling Winthrop Inc. |
Morpholinoalkylindenes as antiglaucoma agents
|
TW252112B
(pt)
|
1993-08-19 |
1995-07-21 |
Pfizer |
|
FR2714057B1
(fr)
|
1993-12-17 |
1996-03-08 |
Sanofi Elf |
Nouveaux dérivés du 3-pyrazolecarboxamide, procédé pour leur préparation et compositions pharmaceutiques les contenant.
|
IL112290A
(en)
|
1994-01-12 |
1999-01-26 |
Novartis Ag |
Transformed aryl and the troiryl pyrimidines and herbicides containing them
|
US5705515A
(en)
|
1994-04-26 |
1998-01-06 |
Merck & Co., Inc. |
Substituted sulfonamides as selective β-3 agonists for the treatment of diabetes and obesity
|
EP0685466A1
(de)
|
1994-06-02 |
1995-12-06 |
Ciba-Geigy Ag |
3-Heteroaliphatyl- und 3-Hetero-(aryl)aliphatyl-2(1H)-chinolonderivate
|
JPH0862604A
(ja)
|
1994-06-13 |
1996-03-08 |
Mitsui Petrochem Ind Ltd |
液晶素子およびその製造方法
|
US5888420A
(en)
|
1994-06-13 |
1999-03-30 |
Mitsui Chemicals, Inc. |
Liquid crystal device and process for preparing the same
|
CA2203878C
(en)
|
1994-11-07 |
2002-06-25 |
John M. Peterson |
Certain substituted benzylamine derivatives; a new class of neuropeptide y1 specific ligands
|
WO1996023517A1
(en)
|
1995-01-31 |
1996-08-08 |
Eli Lilly And Company |
Anti-obesity proteins
|
US5554727A
(en)
|
1995-01-31 |
1996-09-10 |
Eli Lilly And Company |
Anti-obesity proteins
|
US5605886A
(en)
|
1995-01-31 |
1997-02-25 |
Eli Lilly And Company |
Anti-obesity proteins
|
CA2211656A1
(en)
|
1995-01-31 |
1996-08-08 |
Margret B. Basinski |
Anti-obesity proteins
|
US5552522A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
US5559208A
(en)
|
1995-01-31 |
1996-09-24 |
Eli Lilly And Company |
Anti-obesity proteins
|
US5552523A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
US5552524A
(en)
|
1995-01-31 |
1996-09-03 |
Eli Lilly And Company |
Anti-obesity proteins
|
US5521283A
(en)
|
1995-01-31 |
1996-05-28 |
Eli Lilly And Company |
Anti-obesity proteins
|
US5760038A
(en)
|
1995-02-06 |
1998-06-02 |
Bristol-Myers Squibb Company |
Substituted biphenyl sulfonamide endothelin antagonists
|
US5780473A
(en)
|
1995-02-06 |
1998-07-14 |
Bristol-Myers Squibb Company |
Substituted biphenyl sulfonamide endothelin antagonists
|
US5532237A
(en)
|
1995-02-15 |
1996-07-02 |
Merck Frosst Canada, Inc. |
Indole derivatives with affinity for the cannabinoid receptor
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
US20020006964A1
(en)
|
1995-05-16 |
2002-01-17 |
Young James W. |
Methods of using and compositions comprising (+) sibutramine optionally in combination with other pharmacologically active compounds
|
JPH08327993A
(ja)
|
1995-05-30 |
1996-12-13 |
Mitsui Petrochem Ind Ltd |
液晶素子
|
US5739106A
(en)
|
1995-06-07 |
1998-04-14 |
Rink; Timothy J. |
Appetite regulating compositions
|
GB9522007D0
(en)
|
1995-10-27 |
1996-01-03 |
Fujisawa Pharmaceutical Co |
New compound
|
FR2741621B1
(fr)
|
1995-11-23 |
1998-02-13 |
Sanofi Sa |
Nouveaux derives de pyrazole, procede pour leur preparation et compositions pharmaceutiques en contenant
|
AU7692896A
(en)
|
1995-12-01 |
1997-06-27 |
Novartis Ag |
Quinazolin-2,4-diazirines as NPY receptor antagonist
|
AU1328197A
(en)
|
1995-12-01 |
1997-06-19 |
Synaptic Pharmaceutical Corporation |
Aryl sulfonamide and sulfamide derivatives and uses thereof
|
WO1997020820A1
(en)
|
1995-12-01 |
1997-06-12 |
Novartis Ag |
Heteroaryl compounds
|
AU7692996A
(en)
|
1995-12-01 |
1997-06-27 |
Ciba-Geigy Ag |
Receptor antagonists
|
WO1997020821A1
(en)
|
1995-12-01 |
1997-06-12 |
Novartis Ag |
Heteroaryl derivatives
|
TW432073B
(en)
|
1995-12-28 |
2001-05-01 |
Pfizer |
Pyrazolopyridine compounds
|
EP0906103A1
(en)
|
1995-12-29 |
1999-04-07 |
Smithkline Beecham Corporation |
Vitronectin receptor antagonists
|
ATE236137T1
(de)
|
1996-02-02 |
2003-04-15 |
Merck & Co Inc |
Heterocyclische verbindungen als antidiabetische mittel und für die behandlung von fettleibigkeit
|
ES2241036T3
(es)
|
1996-02-02 |
2005-10-16 |
MERCK & CO., INC. |
Procedimiento de tratamiento de diabetes y estados patologicos asociados.
|
DE69728267T2
(de)
|
1996-02-02 |
2005-02-24 |
Merck & Co., Inc. |
Antidiabetisches mittel
|
ATE245622T1
(de)
|
1996-02-02 |
2003-08-15 |
Merck & Co Inc |
Antidiabetische mittel
|
EP0887340A4
(en)
|
1996-02-06 |
2000-03-29 |
Japan Tobacco Inc |
CHEMICAL COMPOUNDS AND THEIR PHARMACEUTICAL USE
|
JPH09274290A
(ja)
|
1996-02-07 |
1997-10-21 |
Fuji Photo Film Co Ltd |
ハロゲン化銀写真感光材料用の現像液および処理方法
|
CN1161202A
(zh)
|
1996-03-14 |
1997-10-08 |
袁安令 |
无伤疤复原型烧烫伤药品配方
|
DE69716810T2
(de)
|
1996-05-15 |
2003-02-27 |
Pfizer |
2,3-Disubstituierte-(5,6)-heteroarylkondensierte-pyrimidin-4-one
|
IT1288388B1
(it)
|
1996-11-19 |
1998-09-22 |
Angeletti P Ist Richerche Bio |
Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
|
US6180653B1
(en)
|
1996-12-16 |
2001-01-30 |
Banyu Pharmaceutical Co., Ltd. |
Aminopyrazole derivatives
|
JPH10237049A
(ja)
|
1996-12-24 |
1998-09-08 |
Nippon Chemiphar Co Ltd |
ベンズイソキサゾ−ル誘導体
|
ES2425559T5
(es)
|
1997-01-07 |
2018-02-02 |
Amylin Pharmaceuticals, Llc |
Composiciones farmacéuticas que comprenden las exendinas y los agonistas de las mismas
|
EP0971588B1
(en)
|
1997-01-21 |
2004-03-17 |
Smithkline Beecham Corporation |
Novel cannabinoid receptor modulators
|
WO1998033765A1
(en)
|
1997-02-04 |
1998-08-06 |
E.I. Du Pont De Nemours And Company |
Fungicidal carboxamides
|
AU735137B2
(en)
|
1997-02-21 |
2001-07-05 |
Bayer Intellectual Property Gmbh |
Arylsulphonamides and analogues and their use for the treatment and neurovegetative disorders
|
JP2001516361A
(ja)
|
1997-03-18 |
2001-09-25 |
スミスクライン・ビーチャム・コーポレイション |
新規カンナビノイド受容体作動薬
|
FR2761266B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique formee par granulation humide pour l'administration orale d'un derive du n-piperidino-3- pyrazolecarboxamide, de ses sels et de leurs solvates
|
FR2761265B1
(fr)
|
1997-03-28 |
1999-07-02 |
Sanofi Sa |
Composition pharmaceutique pour l'administration orale d'un derive du n-piperidino-3-pyrazolecarboxamide, de ses sels et de leurs solvates
|
AU7079498A
(en)
|
1997-04-23 |
1998-11-13 |
Banyu Pharmaceutical Co., Ltd. |
Neuropeptide y receptor antagonist
|
US6001836A
(en)
|
1997-05-28 |
1999-12-14 |
Bristol-Myers Squibb Company |
Dihydropyridine NPY antagonists: cyanoguanidine derivatives
|
SE9702457D0
(sv)
|
1997-06-26 |
1997-06-26 |
Pharmacia & Upjohn Ab |
Screening
|
WO1999002499A1
(fr)
|
1997-07-11 |
1999-01-21 |
Japan Tobacco Inc. |
Composes quinoline et utilisations de ceux-ci en medecine
|
US6251912B1
(en)
|
1997-08-01 |
2001-06-26 |
American Cyanamid Company |
Substituted quinazoline derivatives
|
US6369067B1
(en)
|
1997-10-27 |
2002-04-09 |
Dr. Reddy's Research Foundation |
Monocyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them
|
JP2001523688A
(ja)
|
1997-11-14 |
2001-11-27 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
新規エキセンジン・アゴニスト化合物
|
JPH11209366A
(ja)
|
1998-01-23 |
1999-08-03 |
Nissan Chem Ind Ltd |
クロマン誘導体及び心不全治療薬
|
JPH11279158A
(ja)
|
1998-02-09 |
1999-10-12 |
Pfizer Prod Inc |
キナゾリン―4―オン誘導体の製造方法
|
AU3285499A
(en)
*
|
1998-02-13 |
1999-08-30 |
G.D. Searle & Co. |
Substituted pyridines useful for inhibiting cholesteryl ester transfer protein activity
|
JP2002510688A
(ja)
|
1998-04-02 |
2002-04-09 |
ニューロゲン コーポレイション |
アミノアルキル置換9H−ピリジノ[2,3−b]インドールおよび9H−ピリミジノ[4,5−b]インドール誘導体
|
CN1208326C
(zh)
|
1998-04-23 |
2005-06-29 |
雷迪实验室有限公司 |
杂环化合物及其在医药方面的应用、其制备方法及含有它们的药物组合物
|
IL139239A0
(en)
|
1998-04-27 |
2001-11-25 |
Centre Nat Rech Scient |
3-(amino-or aminoalkyl) pyridinone derivatives and their use for the treatment of hiv related diseases
|
DE69918296T2
(de)
|
1998-04-29 |
2005-08-04 |
Ortho-Mcneil Pharmaceutical, Inc. |
N-substituierte aminotetraline als neuropeptid y y5 rezeptor-liganden und ihre anwendung zur behandlung von fettleibigkeit und anderen erkrankungen
|
US6329395B1
(en)
|
1998-06-08 |
2001-12-11 |
Schering Corporation |
Neuropeptide Y5 receptor antagonists
|
EP1085869A4
(en)
|
1998-06-11 |
2001-10-04 |
Merck & Co Inc |
SPIRO PIPERID DERIVATIVES AS MELANOCORTIN RECEPTORAGONISTS
|
DE19837627A1
(de)
|
1998-08-19 |
2000-02-24 |
Bayer Ag |
Neue Aminosäureester von Arylsulfonamiden und Analoga
|
HN1998000027A
(es)
|
1998-08-19 |
1999-06-02 |
Bayer Ip Gmbh |
Arilsulfonamidas y analagos
|
US6358951B1
(en)
|
1998-08-21 |
2002-03-19 |
Pfizer Inc. |
Growth hormone secretagogues
|
US6337332B1
(en)
|
1998-09-17 |
2002-01-08 |
Pfizer Inc. |
Neuropeptide Y receptor antagonists
|
GT199900147A
(es)
|
1998-09-17 |
1999-09-06 |
|
1, 2, 3, 4- tetrahidroquinolinas 2-sustituidas 4-amino sustituidas.
|
US6147089A
(en)
|
1998-09-17 |
2000-11-14 |
Pfizer Inc. |
Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
|
US6197786B1
(en)
|
1998-09-17 |
2001-03-06 |
Pfizer Inc |
4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
|
US6147090A
(en)
|
1998-09-17 |
2000-11-14 |
Pfizer Inc. |
4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
|
US6297258B1
(en)
|
1998-09-29 |
2001-10-02 |
American Cyanamid Company |
Substituted 3-cyanoquinolines
|
US6147018A
(en)
|
1998-09-29 |
2000-11-14 |
E. I. Du Pont De Nemours And Company |
Hybrid protective composite
|
BR9914164A
(pt)
|
1998-09-29 |
2001-06-26 |
American Cyanamid Co |
Composto, método para o tratamento, inibição do crescimento de, ou erradiacação de um neoplasma, e de doença de rim policìstico, em um mamìfero em necessidade do mesmo, composição farmacêutica, e, processo para preparar um composto
|
EP1121111B1
(en)
|
1998-10-15 |
2010-02-10 |
Imperial Innovations Limited |
Compounds for the treatment of weight loss
|
ATE314371T1
(de)
|
1998-11-10 |
2006-01-15 |
Merck & Co Inc |
Spiro-indole als y5-rezeptor antagonisten
|
ES2161594B1
(es)
|
1998-12-17 |
2003-04-01 |
Servier Lab |
Nuevos derivados de la hidrazida, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
|
SI1144411T1
(en)
|
1998-12-19 |
2005-10-31 |
Janssen Pharmaceutica N.V. |
Antihistaminic spiro compounds
|
US6844368B1
(en)
|
1998-12-22 |
2005-01-18 |
Edward Roberts |
Compounds useful in pain management
|
US6344481B1
(en)
|
1999-03-01 |
2002-02-05 |
Pfizer Inc. |
Thyromimetic antiobesity agents
|
IL145240A
(en)
|
1999-03-19 |
2007-02-11 |
Abbott Gmbh & Co Kg |
Compound and its use in the treatment of eating disorders
|
AU2830800A
(en)
|
1999-03-25 |
2000-10-16 |
Nissan Chemical Industries Ltd. |
Chroman derivatives
|
FR2792314B1
(fr)
|
1999-04-15 |
2001-06-01 |
Adir |
Nouveaux composes aminotriazoles, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
AU775166B2
(en)
|
1999-04-22 |
2004-07-22 |
H. Lundbeck A/S |
Selective NPY (Y5) antagonists
|
US6340683B1
(en)
|
1999-04-22 |
2002-01-22 |
Synaptic Pharmaceutical Corporation |
Selective NPY (Y5) antagonists (triazines)
|
WO2000068197A1
(en)
|
1999-05-05 |
2000-11-16 |
Ortho-Mcneil Pharmaceutical, Inc. |
3a,4,5,9b-TETRAHYDRO-1H-BENZ[e]INDOL-2-YL AMINE-DERIVED NEUROPEPTIDE Y RECEPTORS LIGANDS USEFUL IN THE TREATMENT OF OBESITY AND OTHER DISORDERS
|
US6291476B1
(en)
|
1999-05-12 |
2001-09-18 |
Ortho-Mcneil Pharmaceutical, Inc. |
Pyrazole carboxamides useful for the treatment of obesity and other disorders
|
CA2377369A1
(en)
|
1999-06-04 |
2000-12-14 |
Merck & Co., Inc. |
Substituted piperidines as melanocortin-4 receptor agonists
|
WO2001002379A1
(en)
|
1999-06-30 |
2001-01-11 |
Synaptic Pharmaceutical Corporation |
Selective npy (y5) antagonists
|
AU6000900A
(en)
|
1999-07-23 |
2001-02-13 |
Astrazeneca Uk Limited |
Carbazole derivatives and their use as neuropeptide y5 receptor ligands
|
WO2001009120A1
(en)
|
1999-07-28 |
2001-02-08 |
Ortho-Mcneil Pharmaceutical, Inc. |
Amine and amide derivatives as ligands for the neuropeptide y y5 receptor useful in the treatment of obesity and other disorders
|
TWI279402B
(en)
|
1999-08-20 |
2007-04-21 |
Banyu Pharma Co Ltd |
Spiro compounds having NPY antagonistic activities and agents containing the same
|
CN1377356A
(zh)
|
1999-09-30 |
2002-10-30 |
纽罗杰有限公司 |
亚烷基二胺取代的杂环
|
AU7737900A
(en)
|
1999-09-30 |
2001-04-30 |
Neurogen Corporation |
Amino substituted pyrazolo(1,5,-a)-1,5-pyrimidines and pyrazolo(1,5-a)-1,3,5-triazines
|
US6372743B1
(en)
|
1999-09-30 |
2002-04-16 |
Neurogen Corporation |
Certain alkylene diamine-substituted pyrazlo (1,5-a)-1,5-pyrimidines and pyrazolo (1,5-a) 1,3,5-triazines
|
AU769430B2
(en)
|
1999-10-13 |
2004-01-29 |
Pfizer Products Inc. |
Biaryl ether derivatives useful as monoamine reuptake inhibitors
|
DE19949319A1
(de)
|
1999-10-13 |
2001-06-13 |
Ruetgers Vft Ag |
Verfahren zur Herstellung von Arylalkylethern
|
PL356485A1
(en)
|
1999-12-16 |
2004-06-28 |
Schering Corporation |
Substituted imidazole neuropeptide y y5 receptor antagonists
|
AR042578A1
(es)
|
2000-01-31 |
2005-06-29 |
Genaera Corp |
Inhibidores de la sintesis de mucina
|
US7345051B2
(en)
|
2000-01-31 |
2008-03-18 |
Genaera Corporation |
Mucin synthesis inhibitors
|
AU2001228325A1
(en)
|
2000-02-01 |
2001-08-14 |
Novo-Nordisk A/S |
Use of compounds for the regulation of food intake
|
WO2001057018A1
(en)
|
2000-02-02 |
2001-08-09 |
Abbott Laboratories |
Azaazulene inhibitors of p38 map kinase and tnf-alpha
|
AU2001234958A1
(en)
|
2000-02-11 |
2001-08-20 |
Bristol-Myers Squibb Company |
Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators for treating respiratory and non-respiratory diseases
|
ATE437862T1
(de)
|
2000-02-16 |
2009-08-15 |
Smithkline Beecham Plc |
Pyrimidin-5-onderivate als ldl-pla2 inhibitoren
|
GB0004003D0
(en)
|
2000-02-22 |
2000-04-12 |
Knoll Ag |
Therapeutic agents
|
AU2001234128B2
(en)
|
2000-02-22 |
2004-11-11 |
Banyu Pharmaceutical Co., Ltd. |
Novel imidazoline compounds
|
US6531478B2
(en)
|
2000-02-24 |
2003-03-11 |
Cheryl P. Kordik |
Amino pyrazole derivatives useful for the treatment of obesity and other disorders
|
FR2805810B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives de 3- amino-azetidine, les nouveaux derives et leur preparation
|
FR2805818B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
|
FR2805817B1
(fr)
|
2000-03-03 |
2002-04-26 |
Aventis Pharma Sa |
Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
|
EP1132389A1
(en)
|
2000-03-06 |
2001-09-12 |
Vernalis Research Limited |
New aza-indolyl derivatives for the treatment of obesity
|
US6384051B1
(en)
|
2000-03-13 |
2002-05-07 |
American Cyanamid Company |
Method of treating or inhibiting colonic polyps
|
CN100393703C
(zh)
|
2000-03-14 |
2008-06-11 |
埃科特莱茵药品有限公司 |
1,2,3,4-四氢异喹啉的衍生物
|
CA2403631A1
(en)
|
2000-03-23 |
2001-09-27 |
Brenda L. Palucki |
Spiropiperidine derivatives as melanocortin receptor agonists
|
AU2001249296B2
(en)
|
2000-03-23 |
2005-03-24 |
Merck Sharp & Dohme Corp. |
Substituted piperidines as melanocortin receptor agonists
|
US6600015B2
(en)
|
2000-04-04 |
2003-07-29 |
Hoffmann-La Roche Inc. |
Selective linear peptides with melanocortin-4 receptor (MC4-R) agonist activity
|
EP1142886A1
(en)
|
2000-04-07 |
2001-10-10 |
Aventis Pharma Deutschland GmbH |
Percyquinnin, a process for its production and its use as a pharmaceutical
|
DE60142961D1
(de)
|
2000-04-28 |
2010-10-14 |
Takeda Pharmaceutical |
Antagonisten des melanin-konzentrierenden hormons
|
GB0010757D0
(en)
|
2000-05-05 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
GB0011013D0
(en)
|
2000-05-09 |
2000-06-28 |
Astrazeneca Ab |
Chemical compounds
|
US6432960B2
(en)
|
2000-05-10 |
2002-08-13 |
Bristol-Myers Squibb Company |
Squarate derivatives of dihydropyridine NPY antagonists
|
US6444675B2
(en)
|
2000-05-10 |
2002-09-03 |
Bristol-Myers Squibb Company |
4-alkyl and 4-cycloalkyl derivatives of dihydropyridine NPY antagonists
|
WO2001085173A1
(en)
|
2000-05-10 |
2001-11-15 |
Bristol-Myers Squibb Company |
Alkylamine derivatives of dihydropyridine npy antagonists
|
DE60115227T2
(de)
|
2000-05-11 |
2006-08-24 |
Bristol-Myers Squibb Co. |
Tetrahydroisochinolin-analoga als wachstumshormon-sekretagoga
|
AU2001256733A1
(en)
|
2000-05-16 |
2001-11-26 |
Takeda Chemical Industries Ltd. |
Melanin-concentrating hormone antagonist
|
WO2001087335A2
(en)
|
2000-05-17 |
2001-11-22 |
Eli Lilly And Company |
Method for selectively inhibiting ghrelin action
|
US6391881B2
(en)
|
2000-05-19 |
2002-05-21 |
Bristol-Myers Squibb Company |
Thiourea derivatives of dihydropyridine NPY antagonists
|
SE0001899D0
(sv)
|
2000-05-22 |
2000-05-22 |
Pharmacia & Upjohn Ab |
New compounds
|
EP1289526A4
(en)
|
2000-05-30 |
2005-03-16 |
Merck & Co Inc |
MELANOCORTIN RECEPTOR AGONISTS
|
AU2000252458A1
(en)
*
|
2000-06-08 |
2001-12-17 |
Shizuoka Coffein Co., Ltd. |
Benzene derivatives
|
WO2001094300A1
(de)
|
2000-06-09 |
2001-12-13 |
Aventis Pharma Deutschland Gmbh |
Acylphenylharnstoffderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
|
PE20020665A1
(es)
|
2000-06-15 |
2002-08-14 |
Pharmacia Corp |
ACIDO CICLOALQUIL FENIL ALCANOICO COMO ANTAGONISTA DE INTEGRINAS OVß3
|
US6921767B2
(en)
|
2000-06-15 |
2005-07-26 |
Pharmacia Corporation |
Cycloalkyl alkanoic acids as integrin receptor antagonists derivatives
|
WO2001096302A1
(en)
|
2000-06-16 |
2001-12-20 |
Smithkline Beecham P.L.C. |
Piperidines for use as orexin receptor antagonists
|
CA2384041A1
(en)
|
2000-07-05 |
2002-01-24 |
Synaptic Pharmaceuticals Corporation |
Selective melanin concentrating hormone-1 (mch1) receptor antagonists and uses thereof
|
US6569861B2
(en)
|
2000-07-06 |
2003-05-27 |
Neurogen Corporation |
Melanin concentrating hormone receptor ligands
|
CA2409337A1
(en)
|
2000-07-07 |
2002-01-17 |
Lg Life Sciences Ltd. |
Novel cephalosporin compounds and process for preparing the same
|
GB0019357D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel phenyl guanidines
|
WO2002008250A2
(en)
|
2000-07-24 |
2002-01-31 |
Ardana Bioscience Limited |
Ghrelin antagonists
|
AU8395501A
(en)
|
2000-07-31 |
2002-02-13 |
Hoffmann La Roche |
Piperazine derivatives
|
US6768024B1
(en)
|
2000-08-04 |
2004-07-27 |
Lion Bioscience Ag |
Triamine derivative melanocortin receptor ligands and methods of using same
|
GB0019359D0
(en)
|
2000-08-07 |
2000-09-27 |
Melacure Therapeutics Ab |
Novel guanidines
|
ATE542805T1
(de)
|
2000-08-11 |
2012-02-15 |
Nippon Chemiphar Co |
Ppar-delta aktivatoren
|
US6680340B2
(en)
|
2000-08-21 |
2004-01-20 |
Merck & Co., Inc. |
Anti-hypercholesterolemic drug combination
|
EP1320364A1
(en)
|
2000-08-21 |
2003-06-25 |
Gliatech, Inc. |
The use of histamine h3-receptor inverse agonists for the control of appetite and treatment of obesity
|
JP2004506687A
(ja)
|
2000-08-23 |
2004-03-04 |
メルク エンド カムパニー インコーポレーテッド |
メラノコルチン受容体作働薬としての置換ピペリジン類
|
US6900226B2
(en)
|
2000-09-06 |
2005-05-31 |
Hoffman-La Roche Inc. |
Neuropeptide Y antagonists
|
GB0021831D0
(en)
|
2000-09-06 |
2000-10-18 |
Astrazeneca Ab |
Chemical compounds
|
EP1322628A2
(en)
|
2000-09-14 |
2003-07-02 |
Schering Corporation |
Substituted urea neuropeptide y y5 receptor antagonists
|
WO2002026743A1
(en)
|
2000-09-26 |
2002-04-04 |
Biovitrum Ab |
Novel pyridazine compounds for the treatment of diabetes
|
WO2002026707A1
(en)
|
2000-09-26 |
2002-04-04 |
Biovitrum Ab |
Novel compounds
|
JP2002114768A
(ja)
|
2000-10-11 |
2002-04-16 |
Japan Tobacco Inc |
2−(2,5−ジハロゲン−3,4−ジヒドロキシフェニル)アゾール化合物及びそれを含有してなる医薬組成物
|
EP1326851B1
(en)
|
2000-10-13 |
2004-06-30 |
Eli Lilly And Company |
Substituted dipeptides as growth hormone secretagogues
|
WO2002044152A1
(en)
|
2000-10-16 |
2002-06-06 |
F. Hoffmann-La Roche Ag |
Indoline derivatives and their use as 5-ht2 receptor ligands
|
KR20030044013A
(ko)
|
2000-10-20 |
2003-06-02 |
화이자 프로덕츠 인코포레이티드 |
알파-아릴 에탄올아민 및 이들의 베타-3 아드레날린성수용체 작용제로서의 용도
|
WO2002036596A2
(en)
|
2000-11-03 |
2002-05-10 |
Wyeth |
CYCLOALKYL[b][1,4]DIAZEPINO[6,7,1-hi]INDOLES AND DERIVATIVES
|
EP1335907B1
(en)
|
2000-11-20 |
2010-06-09 |
Biovitrum AB (publ) |
Piperazinylpyrazine compounds as agonist or antagonist of serotonin 5ht-2 receptor
|
ES2328671T3
(es)
|
2000-11-20 |
2009-11-17 |
Biovitrum Ab (Publ) |
Compuestos de piperazilpirazinas como antagonistas del receptor de serotonina 5-ht2.
|
WO2002046173A1
(en)
|
2000-12-06 |
2002-06-13 |
F. Hoffmann-La Roche Ag |
Fused heteroaromatic glucokinase activators
|
WO2002048152A2
(en)
|
2000-12-12 |
2002-06-20 |
Neurogen Corporation |
Spiro[isobenzofuran-1,4'-piperidin]-3-ones and 3h-spiroisobenzofuran-1,4'-piperidines
|
US6482951B2
(en)
|
2000-12-13 |
2002-11-19 |
Hoffmann-La Roche Inc. |
Isoindolin-1-one glucokinase activators
|
GB0030710D0
(en)
|
2000-12-15 |
2001-01-31 |
Hoffmann La Roche |
Piperazine derivatives
|
AR035520A1
(es)
|
2000-12-21 |
2004-06-02 |
Schering Corp |
Compuestos heteroarilo urea que son neuropeptidos y antagonistas de los receptores y5 del neuropeptido y, composiciones farmaceuticas, un proceso para su preparacion, uso de dichos compuestos y composiciones para la manufactura de medicamentos
|
ATE302185T1
(de)
|
2000-12-22 |
2005-09-15 |
Schering Corp |
Piperidin mch antagonisten und ihre verwendung in der behandlung von obesität
|
WO2002051232A2
(en)
|
2000-12-27 |
2002-07-04 |
Actelion Pharmaceuticals Ltd. |
Novel benzazepines and related heterocyclic derivatives
|
KR100539143B1
(ko)
|
2000-12-27 |
2005-12-26 |
에프. 호프만-라 로슈 아게 |
인돌 유도체 및 그의 5-ht2b 및 5-ht2c 수용체리간드로서의 용도
|
US7169777B2
(en)
|
2001-01-23 |
2007-01-30 |
Eli Lilly And Company |
Melanocortin receptor agonists
|
US7157463B2
(en)
|
2001-01-23 |
2007-01-02 |
Eli Lilly And Company |
Substituted piperidines/piperazines as melanocortin receptor agonists
|
CA2432985A1
(en)
|
2001-01-23 |
2002-08-01 |
Vincent Mancuso |
Piperazine- and piperidine-derivatives as melanocortin receptor agonists
|
US7034039B2
(en)
|
2001-02-02 |
2006-04-25 |
Takeda Pharmaceutical Company Limited |
Fused heterocyclic compounds
|
US7507767B2
(en)
|
2001-02-08 |
2009-03-24 |
Schering Corporation |
Cannabinoid receptor ligands
|
US7067539B2
(en)
|
2001-02-08 |
2006-06-27 |
Schering Corporation |
Cannabinoid receptor ligands
|
DE60232238D1
(de)
|
2001-02-28 |
2009-06-18 |
Merck & Co Inc |
Acylierte piperidinderivate als melanocortin-4-rezeptoragonisten
|
US7015235B2
(en)
|
2001-02-28 |
2006-03-21 |
Merck & Co., Inc. |
Acylated piperidine derivatives as melanocortin-4 receptor agonists
|
PL210793B1
(pl)
|
2001-02-28 |
2012-03-30 |
Merck & Co Inc |
Acylowane pochodne piperydyny
|
US7153855B2
(en)
|
2001-03-08 |
2006-12-26 |
Smithkline Beecham Corporation |
Pyrazolopyridinyl pyrimidine therapeutic compounds
|
PT1373216E
(pt)
|
2001-03-22 |
2005-05-31 |
Solvay Pharm Bv |
Derivados de 4,5-diidro-1h-pirazol que possuem actividade antagonista de cb1
|
WO2001074782A1
(en)
|
2001-03-29 |
2001-10-11 |
Molecular Design International, Inc. |
β3-ADRENORECEPTOR AGONISTS, AGONIST COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
|
US7034030B2
(en)
|
2001-03-30 |
2006-04-25 |
Smithkline Beecham Corporation |
Pyralopyridines, process for their preparation and use as therapeutic compounds
|
US7348334B2
(en)
|
2001-04-09 |
2008-03-25 |
Dr. Reddy's Laboratories Limited |
Monocyclic derivatives of aryl alkanoic acids and their use in medicine: process for their preparation and pharmaceutical compositions containing them
|
WO2002083672A1
(en)
|
2001-04-10 |
2002-10-24 |
Smithkline Beecham Corporation |
Antiviral pyrazolopyridine compounds
|
US6573287B2
(en)
|
2001-04-12 |
2003-06-03 |
Bristo-Myers Squibb Company |
2,1-oxazoline and 1,2-pyrazoline-based inhibitors of dipeptidyl peptidase IV and method
|
US6962914B2
(en)
|
2001-04-27 |
2005-11-08 |
Smithkline Beecham Corporation |
Pyrazolopyridinyl pyridine and pyrimidine therapeutic compounds
|
DE10121003A1
(de)
|
2001-04-28 |
2002-12-19 |
Aventis Pharma Gmbh |
Anthranilsäureamide, Verfahren zur Herstellung, ihrer Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen
|
FR2824825B1
(fr)
|
2001-05-15 |
2005-05-06 |
Servier Lab |
Nouveaux derives d'alpha-amino-acides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
JP2004535433A
(ja)
|
2001-06-20 |
2004-11-25 |
メルク エンド カムパニー インコーポレーテッド |
糖尿病治療用のジペプチジルペプチダーゼ阻害薬
|
WO2003000181A2
(en)
|
2001-06-20 |
2003-01-03 |
Merck & Co., Inc. |
Dipeptidyl peptidase inhibitors for the treatment of diabetes
|
GB0115517D0
(en)
|
2001-06-25 |
2001-08-15 |
Ferring Bv |
Novel antidiabetic agents
|
US6684968B2
(en)
|
2001-06-25 |
2004-02-03 |
Kennametal Inc. |
Roof bit body and insert assembly
|
DE60221983T2
(de)
|
2001-06-27 |
2008-05-15 |
Smithkline Beecham Corp. |
Fluorpyrrolidine als dipeptidyl-peptidase inhibitoren
|
EP1399420B1
(en)
|
2001-06-27 |
2007-12-05 |
SmithKline Beecham Corporation |
Pyrrolidines as dipeptidyl peptidase inhibitors
|
DE60222667T2
(de)
|
2001-06-27 |
2008-07-17 |
Smithkline Beecham Corp. |
Fluorpyrrolidine als dipeptidylpeptidaseinhibitoren
|
RU2299066C2
(ru)
|
2001-06-27 |
2007-05-20 |
Пробиодруг Аг |
Новые ингибиторы дипептидилпептидазы iv и их применение в качестве противораковых агентов
|
JP4314614B2
(ja)
|
2001-07-02 |
2009-08-19 |
チバ ホールディング インコーポレーテッド |
薄肉フィルム用途の高分子量ヒドロキシフェニルベンゾトリアゾール紫外線吸収剤
|
ATE388951T1
(de)
|
2001-07-03 |
2008-03-15 |
Novo Nordisk As |
Dpp-iv-inhibierende purin-derivative zur behandlung von diabetes
|
CA2453609C
(en)
|
2001-07-18 |
2010-05-04 |
Merck & Co., Inc. |
Bridged piperidine derivatives as melanocortin receptor agonists
|
AU2002319627A1
(en)
|
2001-07-20 |
2003-03-03 |
Merck And Co., Inc. |
Substituted imidazoles as cannabinoid receptor modulators
|
US6977264B2
(en)
|
2001-07-25 |
2005-12-20 |
Amgen Inc. |
Substituted piperidines and methods of use
|
US6915444B2
(en)
|
2001-09-12 |
2005-07-05 |
Rockwell Automation Technologies, Inc. |
Network independent safety protocol for industrial controller using data manipulation techniques
|
WO2003026591A2
(en)
|
2001-09-24 |
2003-04-03 |
Imperial College Innovations Ltd. |
Modification of feeding behavior
|
US20050015820A1
(en)
|
2001-09-24 |
2005-01-20 |
Michael Cowley |
Assessment of neurons in the arcuate nucleus to screen for agents that modify feeding behavior
|
JP4733922B2
(ja)
|
2002-01-10 |
2011-07-27 |
インペリアル・イノベ−ションズ・リミテッド |
摂食行動の修正
|
US20030158199A1
(en)
|
2002-01-25 |
2003-08-21 |
Kylix, B.V. |
Novel compounds for inhibition of Tie-2
|
US20030225273A1
(en)
|
2002-03-21 |
2003-12-04 |
Michaelides Michael R. |
Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
|
US7560552B2
(en)
|
2002-03-21 |
2009-07-14 |
Abbott Laboratories |
Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
|
US20030181468A1
(en)
|
2002-03-21 |
2003-09-25 |
Michaelides Michael R. |
Thiopyrimidine and isothiazolopyrimidine kinase inhibitors
|
US7166293B2
(en)
|
2002-03-29 |
2007-01-23 |
Carlsbad Technology, Inc. |
Angiogenesis inhibitors
|
US6872827B2
(en)
|
2002-04-26 |
2005-03-29 |
Chembridge Research Laboratories, Inc. |
Somatostatin analogue compounds
|
JP2006508030A
(ja)
|
2002-05-09 |
2006-03-09 |
サイトキネティクス・インコーポレーテッド |
ピリミジノン化合物、組成物および方法
|
GB0211019D0
(en)
|
2002-05-14 |
2002-06-26 |
Syngenta Ltd |
Novel compounds
|
AR037647A1
(es)
|
2002-05-29 |
2004-12-01 |
Novartis Ag |
Derivados de diarilurea utiles para el tratamiento de enfermedades dependientes de la cinasa de proteina
|
WO2004005283A1
(en)
|
2002-07-09 |
2004-01-15 |
Vertex Pharmaceuticals Incorporated |
Imidazoles, oxazoles and thiazoles with protein kinase inhibiting activities
|
US7332514B2
(en)
|
2002-08-30 |
2008-02-19 |
Japan Tobacco Inc. |
Dibenzylamine compound and medicinal use thereof
|
WO2004060400A1
(ja)
|
2003-01-06 |
2004-07-22 |
Mitsubishi Pharma Corp |
上皮成長因子受容体を分子標的とする抗精神病薬
|
JP4330353B2
(ja)
*
|
2003-02-21 |
2009-09-16 |
株式会社静岡カフェイン工業所 |
ピリミジン誘導体
|
US7183287B2
(en)
|
2003-04-03 |
2007-02-27 |
Pharmacia Corporation |
Substituted pyrimidinones
|
JP4885709B2
(ja)
*
|
2003-05-08 |
2012-02-29 |
メルク セローノ ソシエテ アノニム |
ピリジニルアセトニトリル類
|
JP2005015421A
(ja)
|
2003-06-27 |
2005-01-20 |
Nissan Chem Ind Ltd |
o−置換ベンゾイル化合物及びこれを有効成分とする除草剤
|
RU2006106267A
(ru)
|
2003-08-01 |
2006-07-27 |
Уайт Холдингз Корпорейшн (Us) |
Применение комбинации ингибитора киназы рецептора эпидермального фактора роста и цитотоксических средств для лечения и ингибирования рака
|
JP2005060299A
(ja)
|
2003-08-12 |
2005-03-10 |
Nissan Chem Ind Ltd |
置換ピリジン誘導体及びこれを有効成分とする除草剤
|
US7504401B2
(en)
|
2003-08-29 |
2009-03-17 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
JP2005104851A
(ja)
|
2003-09-29 |
2005-04-21 |
Meiji Seika Kaisha Ltd |
新規2−メチレンチオ型カルバペネム誘導体
|
US20050076854A1
(en)
*
|
2003-10-10 |
2005-04-14 |
Passno Richard E. |
Pet enclosure
|
EP1689722A2
(en)
|
2003-10-10 |
2006-08-16 |
Bayer Pharmaceuticals Corporation |
4-aminopyrimidine derivatives for treatment of hyperproliferative disorders
|
WO2005041888A2
(en)
|
2003-11-03 |
2005-05-12 |
Cytokinetics, Inc. |
Pyrimidin-4-one compounds, compositions and methods
|
JP2005194250A
(ja)
|
2004-01-09 |
2005-07-21 |
Sumitomo Chemical Takeda Agro Co Ltd |
トリアゾール化合物、その製造法および用途
|
GT200500008A
(es)
|
2004-01-16 |
2005-08-16 |
|
Intermediarios de quinolina como inhibidores de receptores de tirosina quinasas y la sintesis de los mismos
|
EP1713793A4
(en)
*
|
2004-02-04 |
2009-09-02 |
Smithkline Beecham Corp |
PYRIMIDINONE COMPOUNDS SUITED AS KINASEINHIBITORS
|
WO2005085205A1
(ja)
|
2004-03-05 |
2005-09-15 |
Nissan Chemical Industries, Ltd. |
置換ピラゾール化合物および除草剤
|
KR20050091462A
(ko)
|
2004-03-12 |
2005-09-15 |
한국과학기술연구원 |
푸로피리미딘 화합물 및 이를 포함하는 ddr2 티로신키나아제 활성 저해제
|
US20060035893A1
(en)
|
2004-08-07 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
|
WO2006031806A2
(en)
|
2004-09-10 |
2006-03-23 |
Atherogenics, Inc. |
2-thiopyrimidinones as therapeutic agents
|
WO2006032987A1
(en)
|
2004-09-23 |
2006-03-30 |
Pfizer Products Inc. |
Indoline compounds and their use in the treatment of arteriosclerosis
|
WO2006033001A1
(en)
|
2004-09-23 |
2006-03-30 |
Pfizer Products Inc. |
Quinoline compounds
|
WO2006040646A1
(en)
|
2004-10-14 |
2006-04-20 |
Pfizer, Inc. |
Benzimidazole or indole amides as inhibitors of pin1
|
DE102004055998A1
(de)
|
2004-11-19 |
2006-05-24 |
Rheinische Friedrich-Wilhelms-Universität Bonn |
Niedermolekulare Inhibitoren von Guaninnucleotid-Austauschfaktoren der Cytohesin-Familie
|
AU2006214892B2
(en)
*
|
2005-02-16 |
2013-06-27 |
Kt & G Co., Ltd |
Pharmaceutical composition for the treatment or prevention of diseases involving obesity, diabetes, metabolic syndrome, neuro-degenerative diseases and mitochondria dysfunction diseases
|
WO2006113151A2
(en)
|
2005-04-14 |
2006-10-26 |
Wyeth |
Use of an epidermal growth factor receptor kinase inhibitor (egfr) in gefitinib resistant patients
|
WO2006128129A2
(en)
|
2005-05-26 |
2006-11-30 |
Synta Pharmaceuticals Corp. |
Method for treating cancer
|
US20070032493A1
(en)
|
2005-05-26 |
2007-02-08 |
Synta Pharmaceuticals Corp. |
Method for treating B cell regulated autoimmune disorders
|
DE102005027168A1
(de)
|
2005-06-13 |
2006-12-14 |
Merck Patent Gmbh |
Tetrahydrochinoline
|
DE102005027169A1
(de)
|
2005-06-13 |
2006-12-14 |
Merck Patent Gmbh |
Tetrahydrochinolinderivate
|
US8193206B2
(en)
|
2005-06-14 |
2012-06-05 |
Taigen Biotechnology Co., Ltd. |
Pyrimidine compounds
|
US20060281712A1
(en)
|
2005-06-14 |
2006-12-14 |
Chi-Feng Yen |
Pyrimidine compounds
|
GB0520164D0
(en)
|
2005-10-04 |
2005-11-09 |
Novartis Ag |
Organic compounds
|
WO2007047431A2
(en)
|
2005-10-12 |
2007-04-26 |
Kalypsys, Inc. |
Sulfonyl-substituted aryl compounds as modulators of peroxisome proliferator activated receptors
|
US7973060B2
(en)
|
2005-10-13 |
2011-07-05 |
Crystalgenomics, Inc. |
Fab I inhibitor and process for preparing same
|
UY30117A1
(es)
|
2006-01-31 |
2007-06-29 |
Tanabe Seiyaku Co |
Compuesto amina trisustituido
|
US20070208164A1
(en)
|
2006-02-27 |
2007-09-06 |
Wyeth |
Methods of synthesizing radiolabeled 3-cyano[14C]quinolines
|
JP2007317714A
(ja)
|
2006-05-23 |
2007-12-06 |
Fujifilm Corp |
金属用研磨液
|
US7615643B2
(en)
|
2006-06-02 |
2009-11-10 |
Smithkline Beecham Corporation |
Benzimidazole thiophene compounds
|
US20080280891A1
(en)
|
2006-06-27 |
2008-11-13 |
Locus Pharmaceuticals, Inc. |
Anti-cancer agents and uses thereof
|
CA2654852A1
(en)
|
2006-06-30 |
2008-01-03 |
Astrazeneca Ab |
Pyrimidine derivatives useful in the treatment of cancer
|
TW200817375A
(en)
|
2006-07-21 |
2008-04-16 |
Irm Llc |
Compounds and compositions as ITPKB inhibitors
|
WO2008016811A2
(en)
|
2006-07-31 |
2008-02-07 |
Neurogen Corporation |
Aminopiperidines and realted compounds
|
EA018724B1
(ru)
|
2006-08-07 |
2013-10-30 |
Айронвуд Фармасьютикалз, Инк. |
Соединения индола
|
US8008307B2
(en)
|
2006-08-08 |
2011-08-30 |
Millennium Pharmaceuticals, Inc. |
Heteroaryl compounds useful as inhibitors of E1 activating enzymes
|
US20080045534A1
(en)
|
2006-08-18 |
2008-02-21 |
Valeant Pharmaceuticals North America |
Derivatives of 1,3-diamino benzene as potassium channel modulators
|
EP1894924A1
(en)
|
2006-08-29 |
2008-03-05 |
Phenex Pharmaceuticals AG |
Heterocyclic FXR binding compounds
|
WO2008057280A1
(en)
|
2006-10-27 |
2008-05-15 |
Amgen Inc. |
Multi-cyclic compounds and methods of use
|
DE102006054205A1
(de)
|
2006-11-15 |
2008-05-29 |
Rheinische Friedrich-Wilhelms Universität |
Verwendung von Cytohesin-Inhibitoren zur chemischen Induktion von Langlebigkeit
|
LT2848610T
(lt)
|
2006-11-15 |
2017-11-10 |
Ym Biosciences Australia Pty Ltd |
Kinazės aktyvumo inhibitoriai
|
TW200838526A
(en)
|
2006-12-01 |
2008-10-01 |
Astellas Pharma Inc |
Carboxylic acid derivatives
|
JP2010514695A
(ja)
|
2006-12-21 |
2010-05-06 |
プレキシコン,インコーポレーテッド |
キナーゼ調節のための化合物および方法およびそのための適応症
|
WO2008112156A1
(en)
|
2007-03-08 |
2008-09-18 |
Altiris Therapeutics |
Chemokine receptor modulators
|
US20090118503A1
(en)
|
2007-06-20 |
2009-05-07 |
Kevin Sprott |
Faah inhibitors
|
CN101801942B
(zh)
|
2007-07-17 |
2013-03-27 |
美国艾森生物科学公司 |
杂环化合物和作为抗癌剂的用途
|
WO2009013545A2
(en)
|
2007-07-26 |
2009-01-29 |
Astrazeneca Ab |
Chemical compounds
|
US20100286131A1
(en)
|
2007-08-03 |
2010-11-11 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
TW200918521A
(en)
|
2007-08-31 |
2009-05-01 |
Astrazeneca Ab |
Heterocyclic amides and methods of use thereof
|
US8268849B2
(en)
|
2007-09-25 |
2012-09-18 |
Board Of Regents Of The University Of Nebraska |
Multifunctional Antioxidants and methods of use thereof
|
EP2215065B1
(en)
|
2007-10-19 |
2012-07-11 |
Boehringer Ingelheim International GmbH |
Ccr10 antagonists
|
EP2222660B1
(en)
|
2007-11-16 |
2014-03-26 |
Merck Sharp & Dohme Corp. |
3-heterocyclic substituted indole derivatives and methods of use thereof
|
US8642660B2
(en)
*
|
2007-12-21 |
2014-02-04 |
The University Of Rochester |
Method for altering the lifespan of eukaryotic organisms
|
US20090181846A1
(en)
|
2007-12-24 |
2009-07-16 |
Joung Hyeon Lim |
Process for preparing catalyst for synthesis of carbon nanotubes using spray pyrolysis
|
GB0805477D0
(en)
|
2008-03-26 |
2008-04-30 |
Univ Nottingham |
Pyrimidines triazines and their use as pharmaceutical agents
|
WO2010008739A2
(en)
|
2008-06-20 |
2010-01-21 |
Metabolex, Inc. |
Aryl gpr119 agonists and uses thereof
|
EP2310372B1
(en)
|
2008-07-09 |
2012-05-23 |
Sanofi |
Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
|
WO2010047956A1
(en)
|
2008-10-08 |
2010-04-29 |
Bristol-Myers Squibb Company |
Azolopyrrolone melanin concentrating hormone receptor-1 antagonists
|
MX2011004125A
(es)
|
2008-10-21 |
2011-05-19 |
Metabolex Inc |
Agonistas del receptor gpr120 de arilo y usos de los mismos.
|
CN101723936B
(zh)
|
2008-10-27 |
2014-01-15 |
上海睿星基因技术有限公司 |
激酶抑制剂及其在药学中的用途
|
WO2010085246A1
(en)
|
2009-01-21 |
2010-07-29 |
Praecis Pharmaceuticals Inc |
2,4-diamino-1,3,5-triazine and 4, 6-diamino-pyrimidine derivatives and their use as aggrecanase inhibitors
|
AR076601A1
(es)
|
2009-05-21 |
2011-06-22 |
Chlorion Pharma Inc |
Pirimidinas como agentes terapeuticos
|
US8906944B2
(en)
|
2009-09-03 |
2014-12-09 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
AU2010289359A1
(en)
|
2009-09-03 |
2012-03-29 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
US20120189670A1
(en)
|
2009-09-14 |
2012-07-26 |
Kirkpatrick D Lynn |
Pharmaceutical compositions and formulations including inhibitors of the pleckstrin homology domain and methods for using same
|
WO2011066137A1
(en)
|
2009-11-24 |
2011-06-03 |
Schering Corporation |
Substituted biaryl derivatives and methods of use thereof
|
FR2953145B1
(fr)
|
2009-11-30 |
2013-07-19 |
Inst Francais Du Petrole |
Solution absorbante contenant un inhibiteur de degradation derive de la pyrimidine ou de la triazine et procede d'absorption de composes acides contenus dans un effluent gazeux
|
WO2011082098A1
(en)
|
2009-12-30 |
2011-07-07 |
The Rockefeller University |
Lysine and arginine methyltransferase inhibitors for treating cancer
|
CN104829535A
(zh)
|
2010-01-27 |
2015-08-12 |
贝林格尔·英格海姆国际有限公司 |
作为crth2拮抗剂的吡唑化合物
|
CA2800578A1
(en)
|
2010-05-13 |
2011-11-17 |
Amgen Inc. |
Nitrogen-heterocyclic compounds as phosphodiesterase 10 inhibitors
|
EP2569302A1
(en)
|
2010-05-13 |
2013-03-20 |
Amgen, Inc |
Heteroaryloxyheterocyclyl compounds as pde10 inhibitors
|
KR101564806B1
(ko)
|
2010-05-13 |
2015-10-30 |
암젠 인크 |
Pde10 저해제로서 유용한 질소 헤테로시클릭 화합물
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
EP2588467A1
(en)
|
2010-07-01 |
2013-05-08 |
Amgen Inc. |
Heterocyclic compounds and their use as inhibitors of pi3k activity
|
AU2011271460B2
(en)
|
2010-07-01 |
2014-02-06 |
Amgen Inc. |
Heterocyclic compounds and their use as inhibitors of P13K activity
|
JP2013533884A
(ja)
|
2010-07-02 |
2013-08-29 |
アムジエン・インコーポレーテツド |
Pi3k活性阻害剤としての複素環化合物およびそれらの使用
|
JP2013230986A
(ja)
|
2010-08-25 |
2013-11-14 |
Kyorin Pharmaceutical Co Ltd |
新規ヒダントイン誘導体及びそれらを有効成分とする医薬
|
US8765768B2
(en)
|
2010-11-17 |
2014-07-01 |
Amgen Inc. |
Heterocyclic compounds and their uses
|
US20120184572A1
(en)
|
2011-01-13 |
2012-07-19 |
Metabolex, Inc. |
Aryl gpr119 agonists and uses thereof
|
CN102617480A
(zh)
|
2011-01-30 |
2012-08-01 |
中国人民解放军军事医学科学院毒物药物研究所 |
二-(杂)芳基取代的叔胺类化合物及其制备方法和抗肿瘤应用
|
WO2012120415A1
(en)
|
2011-03-04 |
2012-09-13 |
Novartis Ag |
Tetrasubstituted cyclohexyl compounds as kinase inhibitors
|
SI3002278T1
(sl)
|
2011-03-15 |
2017-08-31 |
Astellas Pharma Inc. |
Spojina guanidina
|
WO2012126181A1
(en)
|
2011-03-24 |
2012-09-27 |
Ying Luo |
Use of kinase inhibitors in preventing and treating inflammatory disorder
|
EP2709609B1
(en)
|
2011-05-17 |
2017-10-04 |
Shionogi & Co., Ltd. |
Heterocyclic compounds
|
US9260416B2
(en)
|
2011-05-27 |
2016-02-16 |
Amira Pharmaceuticals, Inc. |
Heterocyclic autotaxin inhibitors and uses thereof
|
GB201111705D0
(en)
|
2011-07-07 |
2011-08-24 |
Takeda Pharmaceutical |
Compounds and their use
|
DE102011088009A1
(de)
|
2011-12-08 |
2013-06-13 |
Henkel Ag & Co. Kgaa |
Theophyllinderivate zur Repigmentierung von keratinhaltigen Fasern
|
EP2802568A1
(en)
|
2012-01-13 |
2014-11-19 |
Acea Biosciences, Inc. |
Heterocyclic compounds and uses as anticancer agents.
|
CN111840294A
(zh)
|
2012-04-11 |
2020-10-30 |
赛特凯恩蒂克公司 |
改善对骨骼肌疲劳的抵抗力的方法
|
US8633182B2
(en)
|
2012-05-30 |
2014-01-21 |
Boehringer Ingelheim International Gmbh |
Indanyloxyphenylcyclopropanecarboxylic acids
|
US9013997B2
(en)
|
2012-06-01 |
2015-04-21 |
Broadcom Corporation |
System for performing distributed data cut-through
|
CA2875964C
(en)
*
|
2012-06-07 |
2018-01-02 |
Georgia State University Research Foundation, Inc. |
Seca inhibitors and methods of making and using thereof
|
MX2015001793A
(es)
|
2012-08-09 |
2015-05-07 |
Neuropore Therapies Inc |
Derivados de benceno sustituidos con arilo y heteroarilo como moduladores de las trayectorias de señalizacion de cinasa pi3.
|
US20140073634A1
(en)
|
2012-08-24 |
2014-03-13 |
Institute For Applied Cancer Science/The University of Texas MD Anderson Cancer Center |
Heterocyclic modulators of hif activity for treatment of disease
|
KR101667799B1
(ko)
|
2012-09-07 |
2016-10-20 |
삼성디스플레이 주식회사 |
유기금속 화합물 및 이를 포함한 유기 발광 소자
|
FR2996129B1
(fr)
|
2012-09-28 |
2014-12-19 |
Oreal |
Procede de coloration capillaire mettant en oeuvre au moins un derive d'heterocycle azote, un sel de manganese ou de zinc, du peroxyde d'hydrogene et du (bi)carbonate
|
JO3470B1
(ar)
|
2012-10-08 |
2020-07-05 |
Merck Sharp & Dohme |
مشتقات 5- فينوكسي-3h-بيريميدين-4-أون واستخدامها كمثبطات ناسخ عكسي ل hiv
|
US10035790B2
(en)
|
2012-10-19 |
2018-07-31 |
Exelixis, Inc. |
RORγ modulators
|
WO2014079805A1
(en)
|
2012-11-23 |
2014-05-30 |
Boehringer Ingelheim International Gmbh |
Pyrazole compounds for treating hairloss
|
US20160002247A1
(en)
|
2013-03-01 |
2016-01-07 |
The University Of Tokyo |
8-substituted imidazopyrimidinone derivative having autotaxin inhibitory activity
|
CN104059082B
(zh)
|
2013-03-21 |
2016-08-03 |
苏州迈泰生物技术有限公司 |
硝基咪唑杂环类化合物及其在制备治疗结核病药物中的应用
|
CN105339359B
(zh)
|
2013-04-26 |
2018-02-16 |
住友化学株式会社 |
四唑啉酮化合物及其用途
|
WO2014181287A1
(en)
|
2013-05-09 |
2014-11-13 |
Piramal Enterprises Limited |
Heterocyclyl compounds and uses thereof
|
US20140350256A1
(en)
|
2013-05-21 |
2014-11-27 |
University Of Southern Denmark |
Iron and manganese complexes comprising hexadentate monocarboxylato-containing ligands and their use for the catalysis of oxidation reactions
|
WO2015017546A1
(en)
|
2013-07-30 |
2015-02-05 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Selective histone deactylase 6 inhibitors
|
WO2015058163A2
(en)
|
2013-10-18 |
2015-04-23 |
Syros Pharmaceuticals, Inc. |
Inhibitors of cyclin-dependent kinase 7 (cdk7)
|
PT3060550T
(pt)
|
2013-10-21 |
2019-08-27 |
Merck Patent Gmbh |
Compostos de heteroarilo como inibidores de btk e utilizações dos mesmos
|
WO2015069287A1
(en)
|
2013-11-08 |
2015-05-14 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
US9340504B2
(en)
|
2013-11-21 |
2016-05-17 |
Purdue Pharma L.P. |
Pyridine and piperidine derivatives as novel sodium channel blockers
|
CN105017085B
(zh)
*
|
2014-04-28 |
2018-06-29 |
中国科学院上海药物研究所 |
一类kcnq钾通道激动剂、其制备方法和用途
|
MX2017002610A
(es)
*
|
2014-08-29 |
2017-10-11 |
Tes Pharma S R L |
INHIBIDORES DE ACIDO A-AMINO-ß-CARBOXIMUCONICO SEMIALDEHIDO DESCARBOXILASA.
|