AR042578A1 - Inhibidores de la sintesis de mucina - Google Patents
Inhibidores de la sintesis de mucinaInfo
- Publication number
- AR042578A1 AR042578A1 ARP010100437A ARP010100437A AR042578A1 AR 042578 A1 AR042578 A1 AR 042578A1 AR P010100437 A ARP010100437 A AR P010100437A AR P010100437 A ARP010100437 A AR P010100437A AR 042578 A1 AR042578 A1 AR 042578A1
- Authority
- AR
- Argentina
- Prior art keywords
- mucin
- therapeutic composition
- composition according
- diseases
- subject
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
- A61K9/122—Foams; Dry foams
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/724—Cyclodextrins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/10—Expectorants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/12—Mucolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Abstract
Métodos para modular la síntesis de mucina y aplicación terapéutico de compuestos en el control de la superproducción de mucina asociada a enfermedades tales como las enfermedades pulmonares obstructivas crónicas (EPOC), incluyendo el asma y la bronquitis crónica, enfermedades pulmonares inflamatorias, fibrosis cística y enfermedades infecciosas respiratorias aguadas o crónicas. Reivindicación 1: Un método para tratar a un sujeto con una enfermedad caracterizada por la producción de mucina, que comprende administrar al sujeto una cantidad efectiva de una composición que comprende al menos un compuesto que disminuye la síntesis o los niveles de mucina en el sujeto. Reivindicación 20: Una composición terapéutica formulada para administrar por inhalación a los pulmones, que comprende una cantidad efectiva para disminuir la producción o niveles de mucina, de al menos un compuesto seleccionado del grupo integrado por talniflumato, ácido niflúmico, ácido nefenámico, sus derivados, sus sales y prodrogas. Reivindicación 21: Una composición terapéutica de acuerdo con la reivindicación 20, en la cual la composición comprende talniflumato, sus sales y prodrogas. Reivindicación 24: Una composición terapéutica de acuerdo con la reivindicación 20, en la cual la composición comprende, además, al menos un expectorante, una agente mucolítico, un antibiótico o un agente descongestionante. Reivindicación 25: Una composición terapéutica de acuerdo con la reivindicación 24, en la cual el expectorante es guaifenesin. Reivindicación 29: Un dispositivo para inhalación que comprende una composición terapéutica de acuerdo con cualquiera de las reivindicaciones 20-28.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17912700P | 2000-01-31 | 2000-01-31 | |
US19311100P | 2000-03-30 | 2000-03-30 | |
US23078300P | 2000-09-07 | 2000-09-07 | |
US24213400P | 2000-10-23 | 2000-10-23 | |
US25205200P | 2000-11-20 | 2000-11-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR042578A1 true AR042578A1 (es) | 2005-06-29 |
Family
ID=27539006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP010100437A AR042578A1 (es) | 2000-01-31 | 2001-01-31 | Inhibidores de la sintesis de mucina |
Country Status (13)
Country | Link |
---|---|
US (2) | US6737427B2 (es) |
EP (1) | EP1255544B1 (es) |
JP (1) | JP2004507444A (es) |
AR (1) | AR042578A1 (es) |
AT (1) | ATE355836T1 (es) |
AU (2) | AU3467101A (es) |
CA (1) | CA2398642A1 (es) |
CY (1) | CY1106643T1 (es) |
DE (1) | DE60127098T2 (es) |
DK (1) | DK1255544T3 (es) |
ES (1) | ES2282235T3 (es) |
PT (1) | PT1255544E (es) |
WO (1) | WO2001054685A1 (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020147216A1 (en) * | 2000-01-31 | 2002-10-10 | Yuhong Zhou | Mucin synthesis inhibitors |
DE60127098T2 (de) * | 2000-01-31 | 2007-11-29 | Genaera Corp. | Inhibitoren der mucin-synthese |
US7345051B2 (en) * | 2000-01-31 | 2008-03-18 | Genaera Corporation | Mucin synthesis inhibitors |
US8474460B2 (en) | 2000-03-04 | 2013-07-02 | Pulmonx Corporation | Implanted bronchial isolation devices and methods |
US20030059434A1 (en) * | 2000-08-09 | 2003-03-27 | Andrew Grupe | Methods and compositions for treating gastrointestinal tract mucin production associated disease conditions |
US20030050648A1 (en) | 2001-09-11 | 2003-03-13 | Spiration, Inc. | Removable lung reduction devices, systems, and methods |
US6592594B2 (en) | 2001-10-25 | 2003-07-15 | Spiration, Inc. | Bronchial obstruction device deployment system and method |
US6818446B2 (en) | 2001-11-21 | 2004-11-16 | The Regents Of The University Of California | Compositions and methods for the analysis of mucin gene expression and identification of drugs having the ability to inhibit mucin gene expression |
US20030216769A1 (en) | 2002-05-17 | 2003-11-20 | Dillard David H. | Removable anchored lung volume reduction devices and methods |
US20030181922A1 (en) | 2002-03-20 | 2003-09-25 | Spiration, Inc. | Removable anchored lung volume reduction devices and methods |
EP1524942B1 (en) | 2002-07-26 | 2008-09-10 | Emphasys Medical, Inc. | Bronchial flow control devices with membrane seal |
CA2451267A1 (en) * | 2002-12-13 | 2004-06-13 | Warner-Lambert Company Llc | Pharmaceutical uses for alpha2delta ligands |
CN1829526A (zh) | 2003-05-28 | 2006-09-06 | 惠氏公司 | 可溶性clca-1及clca-1的拮抗剂 |
JP2007524618A (ja) * | 2003-06-19 | 2007-08-30 | ジェネーラ・コーポレーション | ムチン合成阻害剤 |
US7533671B2 (en) | 2003-08-08 | 2009-05-19 | Spiration, Inc. | Bronchoscopic repair of air leaks in a lung |
EP1773405A4 (en) * | 2004-07-22 | 2011-10-05 | Duska Scient Co | METHOD FOR DIAGNOSIS, MONITORING AND TREATMENT OF LUNG DISEASES |
US7771472B2 (en) | 2004-11-19 | 2010-08-10 | Pulmonx Corporation | Bronchial flow control devices and methods of use |
WO2006061414A1 (en) * | 2004-12-09 | 2006-06-15 | Ingenium Pharmaceuticals Ag | Methods and agents useful in treating conditions characterized by mucus hyperproduction/ hypersecretion |
WO2006075172A2 (en) * | 2005-01-13 | 2006-07-20 | University Of Dundee | Methods for identifying compounds capable of modulating cftr/ck2 interaction and/or cftr phosphorylation by ck2 |
US8876791B2 (en) | 2005-02-25 | 2014-11-04 | Pulmonx Corporation | Collateral pathway treatment using agent entrained by aspiration flow current |
US7691151B2 (en) | 2006-03-31 | 2010-04-06 | Spiration, Inc. | Articulable Anchor |
EP2043603A4 (en) | 2006-07-11 | 2010-10-27 | Arubor Corp | PREVENTION AND THERAPY OF RHINOSINUSITIS WITH PROINFLAMMATORY CYTOKINHERMERS |
HUE048024T2 (hu) | 2006-08-10 | 2020-05-28 | Roy C Levitt | Anakinra bronchiolitis obliterans szindróma kezelésében való alkalmazásra |
US8093246B2 (en) * | 2006-12-14 | 2012-01-10 | Lexicon Pharmaceuticals, Inc. | O-linked pyrimidin-4-amine-based compounds, compositions comprising them, and methods of their use to treat cancer |
US20100166726A1 (en) * | 2007-03-07 | 2010-07-01 | Northeastern University | Compositions for improving cellular uptake of a chemotherapeutic agent in a cell exhibiting mucin deregulation |
EP2641572B1 (en) | 2007-10-12 | 2019-07-24 | Spiration Inc. | Valve loader method, system, and apparatus |
GB0905954D0 (en) * | 2009-04-06 | 2009-05-20 | E Therapeutics Plc | Treatment of exacerbations of asthma |
CA2797033C (en) * | 2010-04-22 | 2021-10-19 | Longevity Biotech, Inc. | Highly active polypeptides and methods of making and using the same |
WO2012134965A1 (en) * | 2011-03-25 | 2012-10-04 | The Trustees Of Columbia University In The City Of New York | Chloride channel and chloride transporter modulators for therapy in smooth muscle diseases |
EP2758010B1 (en) | 2011-09-23 | 2017-02-08 | Pulmonx, Inc | Implant loading system |
EP2968469A4 (en) | 2013-03-15 | 2016-08-31 | Longevity Biotech Inc | PEPTIDES COMPRISING NON-ENDOGENIC AMINO ACIDS AND METHODS OF MAKING AND USING SAME |
WO2015182565A1 (ja) * | 2014-05-27 | 2015-12-03 | リンク・ジェノミクス株式会社 | 肺疾患治療剤 |
CN113121450A (zh) | 2014-08-29 | 2021-07-16 | Tes制药有限责任公司 | α-氨基-β-羧基粘康酸半醛脱羧酶抑制剂 |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4168313A (en) * | 1978-02-21 | 1979-09-18 | Sebastian Bago | Phthalidyl 2-(3'-trifluoromethyl-anilino)-pyridine-3-carboxylate and its salts |
US4515980A (en) * | 1983-07-11 | 1985-05-07 | Sterling Drug Inc. | Substituted aminobenzoates, their preparation and use |
US4552899A (en) * | 1984-04-09 | 1985-11-12 | Analgesic Associates | Cough/cold mixtures comprising non-steroidal anti-inflammatory drugs |
US4666716A (en) * | 1984-09-04 | 1987-05-19 | Richardson-Vicks Inc. | Antidiarrheal compositions and use thereof |
DE3682136D1 (de) * | 1985-07-31 | 1991-11-28 | Hoechst Ag | N-substituierte 5-nitroanthranilsaeuren, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen. |
DE3608726A1 (de) * | 1986-03-15 | 1987-09-17 | Hoechst Ag | Verwendung aminosubstituierter benzoesaeuren als heilmittel gegen diarrhoe und arzneimittel auf basis dieser verbindungen |
GB9200114D0 (en) * | 1992-01-04 | 1992-02-26 | Scras | Dual inhibitors of no synthase and cyclooxygenase |
WO1996039419A1 (en) | 1995-06-06 | 1996-12-12 | Human Genome Sciences, Inc. | Colon specific genes and proteins |
DE29680627U1 (de) * | 1995-07-20 | 1999-06-02 | Juergens, Uwe R., Dr.med., 53859 Niederkassel | Nicht-steroidales Antiphlogistikum zur topischen und systemischen Behandlung der akuten und chronischen polypoiden Rhinosinusitis |
US5875776A (en) * | 1996-04-09 | 1999-03-02 | Vivorx Pharmaceuticals, Inc. | Dry powder inhaler |
NZ336659A (en) * | 1997-01-08 | 2001-01-26 | Upjohn Co | Pharmaceutically active pyrimido[4,5-b]indoles |
WO1998037881A1 (en) * | 1997-02-28 | 1998-09-03 | Warner Lambert Company | Method of treating or preventing septic shock by administering a mek inhibitor |
ATE344791T1 (de) * | 1997-07-01 | 2006-11-15 | Warner Lambert Co | 2-(4-brom or 4-iod phenylamino)benzoesäurederivate und ihre anwendung als mek-inhibitoren |
AU2674399A (en) * | 1998-02-11 | 1999-08-30 | Regents Of The University Of California, The | Compositions and methods for the inhibition of muc-5 mucin gene expression |
US6576434B1 (en) * | 1998-03-03 | 2003-06-10 | Genaera Corporation | Methods for identification of agents which modulate chloride channel activity |
WO2000040235A2 (en) * | 1999-01-07 | 2000-07-13 | Warner-Lambert Company | Treatment of asthma with mek inhibitors |
AU2201500A (en) * | 1999-01-13 | 2000-08-01 | Warner-Lambert Company | Benzenesulfonamide derivatives and their use as mek inhibitors |
SK9822001A3 (en) * | 1999-01-13 | 2002-08-06 | Warner Lambert Co | 1-heterocycle substituted diarylamines, pharmaceutical compositions based thereon and their use in therapy |
US6245320B1 (en) * | 1999-09-01 | 2001-06-12 | University Of Maryland | Inhibition of mucin release from airway goblet cells by polycationic peptides |
AU7965000A (en) * | 1999-09-27 | 2001-04-30 | Jun-Suk Oh | Use of analgesics as digestive and medicines for expectorating and transdermal therapeutic system using the same |
DE60127098T2 (de) * | 2000-01-31 | 2007-11-29 | Genaera Corp. | Inhibitoren der mucin-synthese |
GB2362101A (en) * | 2000-05-12 | 2001-11-14 | Astrazeneca Ab | Treatment of chronic obstructive pulmonary disease |
-
2001
- 2001-01-31 DE DE60127098T patent/DE60127098T2/de not_active Expired - Fee Related
- 2001-01-31 JP JP2001554669A patent/JP2004507444A/ja active Pending
- 2001-01-31 AR ARP010100437A patent/AR042578A1/es not_active Application Discontinuation
- 2001-01-31 US US09/774,243 patent/US6737427B2/en not_active Expired - Fee Related
- 2001-01-31 AU AU3467101A patent/AU3467101A/xx active Pending
- 2001-01-31 EP EP01906804A patent/EP1255544B1/en not_active Expired - Lifetime
- 2001-01-31 AU AU2001234671A patent/AU2001234671B2/en not_active Ceased
- 2001-01-31 ES ES01906804T patent/ES2282235T3/es not_active Expired - Lifetime
- 2001-01-31 WO PCT/US2001/003078 patent/WO2001054685A1/en active IP Right Grant
- 2001-01-31 PT PT01906804T patent/PT1255544E/pt unknown
- 2001-01-31 AT AT01906804T patent/ATE355836T1/de not_active IP Right Cessation
- 2001-01-31 DK DK01906804T patent/DK1255544T3/da active
- 2001-01-31 CA CA002398642A patent/CA2398642A1/en not_active Abandoned
-
2004
- 2004-05-05 US US10/838,338 patent/US7504409B2/en not_active Expired - Fee Related
-
2007
- 2007-06-05 CY CY20071100747T patent/CY1106643T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
US6737427B2 (en) | 2004-05-18 |
EP1255544A4 (en) | 2005-02-02 |
JP2004507444A (ja) | 2004-03-11 |
AU2001234671B2 (en) | 2006-05-18 |
CA2398642A1 (en) | 2001-08-02 |
ATE355836T1 (de) | 2007-03-15 |
CY1106643T1 (el) | 2012-01-25 |
ES2282235T3 (es) | 2007-10-16 |
EP1255544A1 (en) | 2002-11-13 |
US20010041685A1 (en) | 2001-11-15 |
EP1255544B1 (en) | 2007-03-07 |
WO2001054685A1 (en) | 2001-08-02 |
DE60127098D1 (de) | 2007-04-19 |
DK1255544T3 (da) | 2007-09-17 |
DE60127098T2 (de) | 2007-11-29 |
PT1255544E (pt) | 2007-06-15 |
US20040254096A1 (en) | 2004-12-16 |
US7504409B2 (en) | 2009-03-17 |
AU3467101A (en) | 2001-08-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AR042578A1 (es) | Inhibidores de la sintesis de mucina | |
PT1326595E (pt) | Composicao farmaceutica compreendendo resveratrol para o tratamento de disturbios respiratorios inflamatorios | |
RS52940B (en) | PHARMACEUTICAL FORMULATIONS OF SOLUTION FOR MEASURED DOSES OF PRESSURE INHALATORS | |
ES2809177T3 (es) | Inhalación de levofloxacino para reducir la inflamación pulmonar | |
HRP20130052T1 (hr) | Lijeäśenje respiratorne bolesti | |
NO20061254L (no) | Farmasoytiske blandinger | |
CY1115940T1 (el) | Παραγωγα υποκατεστημενου φαινυλαλκανοϊκου οξεος και η χρηση τους για τη θεραπευτικη αντιμετωπιση αναπνευστικων ασθενειων | |
NO20063693L (no) | Forbindelse og metode for anvendelse | |
CO4950524A1 (es) | Inhibidores de acido nitrico sintasa | |
AR053217A1 (es) | Sales de camostato, proceso para su liofilizacion, formulaciones nebulizadas y de sabor enmascarado que las contienen y el uso de éstas para la fabricacion de un medicamento para el tratamiento de enfermedades pulmonares. | |
ECSP22076862A (es) | Compuestos antivirales y métodos para la administración de los mismos | |
BR0311419A (pt) | Amidinas de tiofeno suas composições e métodos de tratamento de doenças e condições mediadas por complemento | |
WO2012047674A3 (en) | Methods and compositions for disease treatment using inhalation | |
NO20054767L (no) | Sammensetninger omfattende apomorfin for inhalering i lunge | |
BRPI0511030A2 (pt) | agente compreendendo fgf2 como um ingrediente efetivo para tratamento ou prevenção de asma e doença pulmonar obstrutiva crÈnica | |
PE20070828A1 (es) | Composicion farmaceutica que contiene una sal de glicopirronio | |
BR112014004435A2 (pt) | inibidores de quinase rock | |
BR112013027241A2 (pt) | "composto inibidor de rock, composição que o compreende e seus usos" | |
CL2023000532A1 (es) | Derivado de nitrilo que actúa como inhibidor de la dipeptidil peptidasa 1 y su uso | |
UY26564A1 (es) | Inhibidores del factor xa con aril - amidinas y sus derivados, y composiciones farmacéuticas que contienen los mismos | |
AR039409A1 (es) | Composicion farmaceutica en polvo seco para inhalacion, fabricacion y uso. | |
UY28590A1 (es) | Procedimiento para la preparación de nuevas sales de tiotropio, nuevas sales de tiotropio como tales, así como las formulaciones medicamentosas que las contienen. | |
BR112015009504A2 (pt) | inibidores de rock | |
BRPI0506704A (pt) | composições farmacêuticas compreendendo inibidor da bomba de prótons e agente pró-cinético | |
BR112014007684A2 (pt) | tratamento da rinite |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Abandonment or withdrawal |