BR0209774A - Pirimidinas inibidoras de cdk, sua preparação e aplicação como medicamento - Google Patents

Pirimidinas inibidoras de cdk, sua preparação e aplicação como medicamento

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Publication number
BR0209774A
BR0209774A BR0209774-5A BR0209774A BR0209774A BR 0209774 A BR0209774 A BR 0209774A BR 0209774 A BR0209774 A BR 0209774A BR 0209774 A BR0209774 A BR 0209774A
Authority
BR
Brazil
Prior art keywords
preparation
application
pyrimidines
medicament
cdk inhibitor
Prior art date
Application number
BR0209774-5A
Other languages
English (en)
Inventor
Thomas Brumby
Rolf Jautelat
Olaf Prien
Martina Schaefer
Gerhard Siemeister
Ulrich Luecking
Christoph Huwe
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10127581A external-priority patent/DE10127581A1/de
Priority claimed from DE10212098A external-priority patent/DE10212098A1/de
Application filed by Schering Ag filed Critical Schering Ag
Publication of BR0209774A publication Critical patent/BR0209774A/pt

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Abstract

"PIRIMIDINAS INIBIDORAS DE CDK, SUA PREPARAçãO E APLICAçãO COMO MEDICAMENTO". A presente invenção refere-se a derivados de pirimidina da fórmula geral (I), na qual R^ 1^, R^ 2^, X, A e B têm os significados contidos na descrição, como inibidores da quinase dependente de ciclina, sua preparação bem como sua aplicação como medicamento para o tratamento de diversas doenças.
BR0209774-5A 2001-05-29 2002-05-23 Pirimidinas inibidoras de cdk, sua preparação e aplicação como medicamento BR0209774A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE10127581A DE10127581A1 (de) 2001-05-29 2001-05-29 CDK inhibitorische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel
DE10212098A DE10212098A1 (de) 2002-03-11 2002-03-11 CDK inhibitorische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel
PCT/EP2002/005669 WO2002096888A1 (de) 2001-05-29 2002-05-23 Cdk inhibitorische pyrimidine, deren herstellung und verwendung als arzneimittel

Publications (1)

Publication Number Publication Date
BR0209774A true BR0209774A (pt) 2004-06-01

Family

ID=26009483

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BR0209774-5A BR0209774A (pt) 2001-05-29 2002-05-23 Pirimidinas inibidoras de cdk, sua preparação e aplicação como medicamento

Country Status (23)

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US (3) US7235561B2 (pt)
EP (1) EP1392662B1 (pt)
JP (1) JP4291135B2 (pt)
KR (1) KR100874791B1 (pt)
CN (1) CN100480242C (pt)
AR (1) AR036035A1 (pt)
AT (1) ATE420077T1 (pt)
AU (1) AU2002312933B2 (pt)
BR (1) BR0209774A (pt)
CA (1) CA2449118A1 (pt)
CO (1) CO5540316A2 (pt)
DE (1) DE50213202D1 (pt)
ES (1) ES2320204T3 (pt)
HR (1) HRP20031081A2 (pt)
IL (1) IL159120A0 (pt)
ME (1) MEP13408A (pt)
MX (1) MXPA03010810A (pt)
NO (1) NO327129B1 (pt)
NZ (1) NZ529654A (pt)
PL (1) PL367130A1 (pt)
RS (1) RS94703A (pt)
RU (1) RU2330024C2 (pt)
WO (1) WO2002096888A1 (pt)

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EP1453516A2 (de) 2001-10-17 2004-09-08 Boehringer Ingelheim Pharma GmbH & Co.KG 5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren
EP2090571B1 (de) * 2001-10-17 2012-05-16 Boehringer Ingelheim Pharma GmbH & Co. KG Pyrimidinderivate, Arzneimittel enthaltend diese Verbindungen, deren Verwendung und Verfahren zu ihrer Herstellung
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WO2003076434A1 (en) 2002-03-09 2003-09-18 Astrazeneca Ab 4- imidazolyl substuited pyrimidine derivatives with cdk inhibitiory activity
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GB0311276D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
GB0311274D0 (en) 2003-05-16 2003-06-18 Astrazeneca Ab Chemical compounds
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