ATE286062T1 - Verfahren zur herstellung von l-ribavirin - Google Patents

Verfahren zur herstellung von l-ribavirin

Info

Publication number: ATE286062T1
Authority: AT; Austria
Prior art keywords: chem; formula; ribavirin; reaction; group
Prior art date: 2001-07-30

Application number

AT02764788T

Other languages

English (en)

Inventor

Marco Frigerio

Aldo Banfi

Oro Bruno Dall

Alfredo Mancini

Original Assignee

Clariant Lsm Italia Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-07-30

Filing date

2002-07-25

Publication date

2005-01-15

2002-07-25 Application filed by Clariant Lsm Italia Spa filed Critical Clariant Lsm Italia Spa

2005-01-15 Application granted granted Critical

2005-01-15 Publication of ATE286062T1 publication Critical patent/ATE286062T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/056—Triazole or tetrazole radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Catalysts (AREA)

AT02764788T 2001-07-30 2002-07-25 Verfahren zur herstellung von l-ribavirin ATE286062T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01830510A EP1281715B1 (de)	2001-07-30	2001-07-30	Verfahren zur Herstellung von Ribavirin
PCT/EP2002/008330 WO2003011883A2 (en)	2001-07-30	2002-07-25	Process for the preparation of l-ribavirin

Publications (1)

Publication Number	Publication Date
ATE286062T1 true ATE286062T1 (de)	2005-01-15

Family

ID=8184638

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT01830510T ATE252594T1 (de)	2001-07-30	2001-07-30	Verfahren zur herstellung von ribavirin
AT02764788T ATE286062T1 (de)	2001-07-30	2002-07-25	Verfahren zur herstellung von l-ribavirin

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT01830510T ATE252594T1 (de)	2001-07-30	2001-07-30	Verfahren zur herstellung von ribavirin

Country Status (13)

Country	Link
US (2)	US7285660B2 (de)
EP (2)	EP1281715B1 (de)
JP (2)	JP2004538317A (de)
KR (2)	KR20040031784A (de)
CN (2)	CN1255420C (de)
AT (2)	ATE252594T1 (de)
AU (1)	AU2002328974A1 (de)
BR (2)	BR0210278A (de)
DE (2)	DE60101056T2 (de)
ES (2)	ES2208540T3 (de)
HU (2)	HUP0401615A2 (de)
MX (2)	MXPA04000382A (de)
WO (2)	WO2003011883A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2005539032A (ja) *	2002-08-12	2005-12-22	エフ．ホフマン−ラ　ロシュ　アーゲー	リボフラノースの製造方法
WO2007007183A2 (en) *	2005-07-08	2007-01-18	Aurobindo Pharma Limited	Compositions of antiviral compound
JP2008222630A (ja) *	2007-03-12	2008-09-25	Permachem Asia Ltd	１−β−Ｄ−リボフラノシルー１，２，４−トリアゾール−３−カルボキサミドのＲ−ＩＩ型結晶の製造法
CN101891786B (zh) *	2010-08-04	2012-09-05	王明	一种利巴韦林化合物及其制法
EP2646453A1 (de)	2010-11-30	2013-10-09	Gilead Pharmasset LLC	Verbindungen
CN102127134B (zh) *	2010-12-02	2012-11-14	海南美兰史克制药有限公司	一种利巴韦林化合物及其方法
CN102532226B (zh) *	2010-12-15	2014-05-07	上海迪赛诺医药发展有限公司	利巴韦林晶型及其制备方法
CN109134565A (zh) *	2017-08-15	2019-01-04	李双喜	一种1/10水利巴韦林化合物及其药物组合物
CN109134566A (zh) *	2017-08-18	2019-01-04	樊艳芳	一种1/20水利巴韦林化合物
CN108484691A (zh) *	2018-06-28	2018-09-04	牡丹江师范学院	一种利巴韦林缩合物的化学合成方法
CN111647033A (zh) *	2020-06-08	2020-09-11	济南明鑫制药股份有限公司	一锅法制备利巴韦林的方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3798209A (en) *	1971-06-01	1974-03-19	Icn Pharmaceuticals	1,2,4-triazole nucleosides
JPS55160793A (en) *	1979-05-29	1980-12-13	Microbial Chem Res Found	Preparation of virazole
JPS5931797A (ja) *	1982-08-18	1984-02-20	Sumitomo Chem Co Ltd	新規１−置換イミダゾ−ルヌクレオシドおよびその製造法
JPS60252493A (ja) *	1984-05-25	1985-12-13	Takeda Chem Ind Ltd	シチジン誘導体の製造法
KR880011146A (ko) *	1987-03-25	1988-10-26	엠.피.젝슨	3'-아지도-3'-디옥시티미딘의 신규 제조방법 및 이러한 공정에 유용한 중간체
CN1049435C (zh) *	1994-11-09	2000-02-16	中国科学院上海药物研究所	含苯基和杂环基的青蒿素衍生物及其制备方法
EP1254911A1 (de) *	1996-10-16	2002-11-06	ICN Pharmaceuticals, Inc.	Monozyklische L-Nukleoside, analoga und ihre Anwendungen
SK284054B6 (sk) *	1996-10-16	2004-08-03	Icn Pharmaceuticals, Inc.	Substituované triazolové nukleozidy, farmaceutický prostriedok s ich obsahom a ich použitie

2001
- 2001-07-30 EP EP01830510A patent/EP1281715B1/de not_active Expired - Lifetime
- 2001-07-30 ES ES01830510T patent/ES2208540T3/es not_active Expired - Lifetime
- 2001-07-30 DE DE60101056T patent/DE60101056T2/de not_active Expired - Lifetime
- 2001-07-30 AT AT01830510T patent/ATE252594T1/de not_active IP Right Cessation
2002
- 2002-07-25 AT AT02764788T patent/ATE286062T1/de not_active IP Right Cessation
- 2002-07-25 EP EP02764788A patent/EP1414836B1/de not_active Expired - Lifetime
- 2002-07-25 DE DE60202483T patent/DE60202483T2/de not_active Expired - Fee Related
- 2002-07-25 WO PCT/EP2002/008330 patent/WO2003011883A2/en active IP Right Grant
- 2002-07-25 HU HU0401615A patent/HUP0401615A2/hu unknown
- 2002-07-25 MX MXPA04000382A patent/MXPA04000382A/es active IP Right Grant
- 2002-07-25 ES ES02764788T patent/ES2233857T3/es not_active Expired - Lifetime
- 2002-07-25 JP JP2003517074A patent/JP2004538317A/ja active Pending
- 2002-07-25 US US10/485,436 patent/US7285660B2/en not_active Expired - Fee Related
- 2002-07-25 KR KR10-2004-7001404A patent/KR20040031784A/ko not_active Application Discontinuation
- 2002-07-25 CN CNB028149246A patent/CN1255420C/zh not_active Expired - Fee Related
- 2002-07-25 AU AU2002328974A patent/AU2002328974A1/en not_active Abandoned
- 2002-07-25 BR BR0210278-1A patent/BR0210278A/pt not_active IP Right Cessation
- 2002-07-29 US US10/485,335 patent/US7285659B2/en not_active Expired - Lifetime
- 2002-07-29 CN CNB028149254A patent/CN1255421C/zh not_active Expired - Fee Related
- 2002-07-29 KR KR1020047001334A patent/KR100953031B1/ko not_active IP Right Cessation
- 2002-07-29 WO PCT/IB2002/002950 patent/WO2003011884A1/en active Application Filing
- 2002-07-29 BR BR0209815-6A patent/BR0209815A/pt not_active IP Right Cessation
- 2002-07-29 HU HU0401899A patent/HUP0401899A2/hu unknown
- 2002-07-29 JP JP2003517075A patent/JP2004538318A/ja active Pending
- 2002-07-29 MX MXPA03010251A patent/MXPA03010251A/es active IP Right Grant

Also Published As

Publication number	Publication date
KR20040021670A (ko)	2004-03-10
DE60101056D1 (de)	2003-11-27
WO2003011883A2 (en)	2003-02-13
ES2208540T3 (es)	2004-06-16
AU2002328974A1 (en)	2003-02-17
EP1414836B1 (de)	2004-12-29
CN1255421C (zh)	2006-05-10
WO2003011883A3 (en)	2003-04-17
DE60101056T2 (de)	2004-05-19
CN1535277A (zh)	2004-10-06
DE60202483D1 (de)	2005-02-03
CN1535278A (zh)	2004-10-06
BR0209815A (pt)	2004-06-01
US7285660B2 (en)	2007-10-23
HUP0401899A2 (hu)	2004-12-28
KR100953031B1 (ko)	2010-04-14
HUP0401615A2 (hu)	2004-11-29
EP1414836A2 (de)	2004-05-06
US20040192904A1 (en)	2004-09-30
EP1281715A1 (de)	2003-02-05
ES2233857T3 (es)	2005-06-16
JP2004538318A (ja)	2004-12-24
DE60202483T2 (de)	2005-12-29
EP1281715B1 (de)	2003-10-22
US20040176587A1 (en)	2004-09-09
ATE252594T1 (de)	2003-11-15
MXPA04000382A (es)	2004-07-23
MXPA03010251A (es)	2004-03-16
WO2003011884A1 (en)	2003-02-13
BR0210278A (pt)	2004-07-20
CN1255420C (zh)	2006-05-10
KR20040031784A (ko)	2004-04-13
JP2004538317A (ja)	2004-12-24
US7285659B2 (en)	2007-10-23

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Legal Events

Date	Code	Title	Description
2005-06-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties