WO2008114656A1 - リパーゼ粉末製剤、その製造方法及び使用 - Google Patents

リパーゼ粉末製剤、その製造方法及び使用 Download PDF

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Publication number
WO2008114656A1
WO2008114656A1 PCT/JP2008/054448 JP2008054448W WO2008114656A1 WO 2008114656 A1 WO2008114656 A1 WO 2008114656A1 JP 2008054448 W JP2008054448 W JP 2008054448W WO 2008114656 A1 WO2008114656 A1 WO 2008114656A1
Authority
WO
WIPO (PCT)
Prior art keywords
production
lipase
lipase preparation
powdery
powdery lipase
Prior art date
Application number
PCT/JP2008/054448
Other languages
English (en)
French (fr)
Inventor
Junko Suzuki
Yoshie Yamauchi
Tamami Manabe
Satoshi Negishi
Original Assignee
The Nisshin Oillio Group, Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to TW097108453A priority Critical patent/TWI438279B/zh
Application filed by The Nisshin Oillio Group, Ltd. filed Critical The Nisshin Oillio Group, Ltd.
Priority to EP08721864.0A priority patent/EP2141229B1/en
Priority to US12/531,327 priority patent/US8921081B2/en
Priority to ES08721864.0T priority patent/ES2537325T3/es
Priority to AU2008227690A priority patent/AU2008227690B2/en
Priority to CN200880014725A priority patent/CN101675159A/zh
Priority to DK08721864.0T priority patent/DK2141229T3/en
Priority to CA2680863A priority patent/CA2680863C/en
Priority to JP2009505150A priority patent/JP5145609B2/ja
Publication of WO2008114656A1 publication Critical patent/WO2008114656A1/ja
Priority to US14/573,383 priority patent/US20150104839A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/96—Stabilising an enzyme by forming an adduct or a composition; Forming enzyme conjugates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6454—Glycerides by esterification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y301/00—Hydrolases acting on ester bonds (3.1)
    • C12Y301/01—Carboxylic ester hydrolases (3.1.1)
    • C12Y301/01003—Triacylglycerol lipase (3.1.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fats And Perfumes (AREA)

Abstract

　Rhizopus oryzae由来及び/又はRhizopus delemar由来のリパーゼと、脂肪含有量が５質量％以上である大豆粉末とを含有する造粒物であるリパーゼ粉末製剤。このリパーゼ粉末製剤にすることにより、リパーゼ活性が向上する。
PCT/JP2008/054448 2007-03-16 2008-03-12 リパーゼ粉末製剤、その製造方法及び使用 WO2008114656A1 (ja)

Priority Applications (10)

Application Number Priority Date Filing Date Title
TW097108453A TWI438279B (zh) 2007-03-16 2008-03-11 脂肪酶粉末製劑，其製造方法及使用
EP08721864.0A EP2141229B1 (en) 2007-03-16 2008-03-12 Powdery lipase preparation, method for production thereof, and use thereof
US12/531,327 US8921081B2 (en) 2007-03-16 2008-03-12 Powdery lipase preparation, method for producing the same and use thereof
ES08721864.0T ES2537325T3 (es) 2007-03-16 2008-03-12 Preparación de lipasa en polvo, método para la producción de la misma y uso de la misma
AU2008227690A AU2008227690B2 (en) 2007-03-16 2008-03-12 Powdery lipase preparation, method for producing the same and use thereof
CN200880014725A CN101675159A (zh) 2007-03-16 2008-03-12 脂肪酶粉末制剂、其制备方法及应用
DK08721864.0T DK2141229T3 (en) 2007-03-16 2008-03-12 Powdery lipase preparation, process for their preparation and use thereof
CA2680863A CA2680863C (en) 2007-03-16 2008-03-12 Powdery lipase preparation, method for producing the same and use thereof
JP2009505150A JP5145609B2 (ja) 2007-03-16 2008-03-12 リパーゼ粉末製剤、その製造方法及び使用
US14/573,383 US20150104839A1 (en) 2007-03-16 2014-12-17 Powdery lipase preparation, method for producing the same and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-069189 2007-03-16
JP2007069189 2007-03-16

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/531,327 A-371-Of-International US8921081B2 (en) 2007-03-16 2008-03-12 Powdery lipase preparation, method for producing the same and use thereof
US14/573,383 Continuation US20150104839A1 (en) 2007-03-16 2014-12-17 Powdery lipase preparation, method for producing the same and use thereof

Publications (1)

Publication Number Publication Date
WO2008114656A1 true WO2008114656A1 (ja) 2008-09-25

Family

ID=39765764

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/054448 WO2008114656A1 (ja) 2007-03-16 2008-03-12 リパーゼ粉末製剤、その製造方法及び使用

Country Status (13)

Country Link
US (2) US8921081B2 (ja)
EP (1) EP2141229B1 (ja)
JP (1) JP5145609B2 (ja)
KR (1) KR101213082B1 (ja)
CN (2) CN101675159A (ja)
AU (1) AU2008227690B2 (ja)
CA (1) CA2680863C (ja)
DK (1) DK2141229T3 (ja)
ES (1) ES2537325T3 (ja)
MY (1) MY151041A (ja)
RU (1) RU2447148C2 (ja)
TW (1) TWI438279B (ja)
WO (1) WO2008114656A1 (ja)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010089967A1 (ja) * 2009-02-04 2010-08-12 不二製油株式会社 乳化粉末リパーゼ製剤の製造方法
WO2011068076A1 (ja) * 2009-12-01 2011-06-09 日清オイリオグループ株式会社 リパーゼ粉末製剤及びその使用
JP2012017284A (ja) * 2010-07-07 2012-01-26 Adeka Corp リパーゼ製剤及びその製造方法
WO2013027697A1 (ja) * 2011-08-19 2013-02-28 日清オイリオグループ株式会社 リパーゼ活性の回復方法
JP2013049803A (ja) * 2011-08-31 2013-03-14 Nisshin Oillio Group Ltd エステル交換油脂の製造方法及びその装置
JP2015216846A (ja) * 2014-05-14 2015-12-07 長谷川香料株式会社 大豆食品の風味付与剤

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3060668A1 (en) * 2017-05-08 2018-11-15 Bunge Loders Croklaan B.V. Emulsifiers

Citations (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6098984A (ja) 1983-09-05 1985-06-01 ノボ　ノルディスク　アクティーゼルスカブ 固定化リパ−ゼ調製品の製造方法
JPS61202688A (ja) 1985-02-27 1986-09-08 ノボ　ノルディスク　アクティーゼルスカブ 固定化リパーゼ調製品の製造方法
JPS62269685A (ja) * 1986-05-15 1987-11-24 Showa Denko Kk 酵素粒剤
JPH01262795A (ja) 1988-04-11 1989-10-19 Kao Corp 固定化酵素の製造方法
JPH02138986A (ja) 1987-12-22 1990-05-28 Unilever Nv 脂肪酸エステルの製造方法
JPH0361485A (ja) 1989-07-31 1991-03-18 Ajinomoto Co Inc 固定化リパーゼ酵素剤
JP2668187B2 (ja) 1993-09-17 1997-10-27 日清製油株式会社 リパーゼ粉末を用いたエステル交換法
JPH11246893A (ja) 1998-03-04 1999-09-14 Kao Corp 酵素固形製剤の製造方法
JP2000106873A (ja) 1998-10-06 2000-04-18 Nisshin Oil Mills Ltd:The 熱安定性酵素およびその製造法
JP3403202B2 (ja) 1995-06-27 2003-05-06 ユニリーバー・ナームローゼ・ベンノートシャープ 固定された酵素及びトリグリセリド油の加工への使用
WO2006030889A1 (ja) * 2004-09-16 2006-03-23 The Nisshin Oillio Group, Ltd. リパーゼ粉末、その製造方法及びその使用
JP2006325465A (ja) * 2005-05-25 2006-12-07 Nisshin Oillio Group Ltd 官能基交換反応用リパーゼ含有組成物、その製造方法及びその使用
JP2007068426A (ja) * 2005-09-05 2007-03-22 Nisshin Oillio Group Ltd リパーゼ粉末製剤、その製造方法及び使用
WO2008010543A1 (fr) * 2006-07-19 2008-01-24 The Nisshin Oillio Group, Ltd. Procédé destiné à produire un beurre solide adapté à un produit de chocolaterie

Family Cites Families (9)

* Cited by examiner, † Cited by third party
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US3660571A (en) * 1968-03-28 1972-05-02 Takeda Chemical Industries Ltd Disease control composition for silkworms
JPH0640822B2 (ja) 1985-12-13 1994-06-01 旭電化工業株式会社 微生物リポプロテインリパ−ゼの製造方法
JP3690951B2 (ja) * 1999-12-22 2005-08-31 日清オイリオグループ株式会社 油脂のエステル交換反応方法
RU2233325C1 (ru) * 2003-01-08 2004-07-27 Государственное образовательное учреждение Воронежская государственная технологическая академия Способ получения комплексного ферментного препарата липазы и липоксигеназы
WO2004105495A2 (en) * 2003-05-29 2004-12-09 Micro Baked Close Corporation Bread premix and bread produced utilizing same
TW200538464A (en) * 2004-04-08 2005-12-01 Nisshin Oillio Group Ltd A 1,3-specific lipase powder, methods for producing the same and use thereof
MY142014A (en) * 2004-04-08 2010-08-16 Nisshin Oillio Group Ltd A lipase powder, methods for producing the same and use thereof
JP4394598B2 (ja) * 2004-08-24 2010-01-06 日清オイリオグループ株式会社 リパーゼ粉末組成物及びそれを用いたエステル化物の製造方法
US20080280020A1 (en) * 2005-03-16 2008-11-13 Hirofumi Kugitani Process for Production of Soybean Puff

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6098984A (ja) 1983-09-05 1985-06-01 ノボ　ノルディスク　アクティーゼルスカブ 固定化リパ−ゼ調製品の製造方法
JPS61202688A (ja) 1985-02-27 1986-09-08 ノボ　ノルディスク　アクティーゼルスカブ 固定化リパーゼ調製品の製造方法
JPS62269685A (ja) * 1986-05-15 1987-11-24 Showa Denko Kk 酵素粒剤
JPH02138986A (ja) 1987-12-22 1990-05-28 Unilever Nv 脂肪酸エステルの製造方法
JPH01262795A (ja) 1988-04-11 1989-10-19 Kao Corp 固定化酵素の製造方法
JPH0361485A (ja) 1989-07-31 1991-03-18 Ajinomoto Co Inc 固定化リパーゼ酵素剤
JP2668187B2 (ja) 1993-09-17 1997-10-27 日清製油株式会社 リパーゼ粉末を用いたエステル交換法
JP3403202B2 (ja) 1995-06-27 2003-05-06 ユニリーバー・ナームローゼ・ベンノートシャープ 固定された酵素及びトリグリセリド油の加工への使用
JPH11246893A (ja) 1998-03-04 1999-09-14 Kao Corp 酵素固形製剤の製造方法
JP2000106873A (ja) 1998-10-06 2000-04-18 Nisshin Oil Mills Ltd:The 熱安定性酵素およびその製造法
WO2006030889A1 (ja) * 2004-09-16 2006-03-23 The Nisshin Oillio Group, Ltd. リパーゼ粉末、その製造方法及びその使用
JP2006325465A (ja) * 2005-05-25 2006-12-07 Nisshin Oillio Group Ltd 官能基交換反応用リパーゼ含有組成物、その製造方法及びその使用
JP2007068426A (ja) * 2005-09-05 2007-03-22 Nisshin Oillio Group Ltd リパーゼ粉末製剤、その製造方法及び使用
WO2008010543A1 (fr) * 2006-07-19 2008-01-24 The Nisshin Oillio Group, Ltd. Procédé destiné à produire un beurre solide adapté à un produit de chocolaterie

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2141229A4

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010089967A1 (ja) * 2009-02-04 2010-08-12 不二製油株式会社 乳化粉末リパーゼ製剤の製造方法
JP5585454B2 (ja) * 2009-02-04 2014-09-10 不二製油株式会社 乳化粉末リパーゼ製剤の製造方法
WO2011068076A1 (ja) * 2009-12-01 2011-06-09 日清オイリオグループ株式会社 リパーゼ粉末製剤及びその使用
CN102575238A (zh) * 2009-12-01 2012-07-11 日清奥利友集团株式会社 脂肪酶粉末制剂及其用途
EP2508598A1 (en) * 2009-12-01 2012-10-10 The Nisshin OilliO Group, Ltd. Lipase powder preparation and use thereof
EP2508598A4 (en) * 2009-12-01 2013-05-29 Nisshin Oillio Group Ltd PREPARATION OF LIPASE POWDER AND USE THEREOF
JP2012017284A (ja) * 2010-07-07 2012-01-26 Adeka Corp リパーゼ製剤及びその製造方法
WO2013027697A1 (ja) * 2011-08-19 2013-02-28 日清オイリオグループ株式会社 リパーゼ活性の回復方法
JP2013039109A (ja) * 2011-08-19 2013-02-28 Nisshin Oillio Group Ltd リパーゼ活性の回復方法
JP2013049803A (ja) * 2011-08-31 2013-03-14 Nisshin Oillio Group Ltd エステル交換油脂の製造方法及びその装置
JP2015216846A (ja) * 2014-05-14 2015-12-07 長谷川香料株式会社 大豆食品の風味付与剤

Also Published As

Publication number Publication date
ES2537325T3 (es) 2015-06-05
US8921081B2 (en) 2014-12-30
CN101675159A (zh) 2010-03-17
CA2680863A1 (en) 2008-09-25
US20100112650A1 (en) 2010-05-06
TW200848513A (en) 2008-12-16
AU2008227690A1 (en) 2008-09-25
JPWO2008114656A1 (ja) 2010-07-01
TWI438279B (zh) 2014-05-21
CN104962535B (zh) 2018-11-02
EP2141229B1 (en) 2015-05-13
RU2447148C2 (ru) 2012-04-10
KR101213082B1 (ko) 2012-12-17
AU2008227690B2 (en) 2013-09-05
US20150104839A1 (en) 2015-04-16
JP5145609B2 (ja) 2013-02-20
KR20090122241A (ko) 2009-11-26
CN104962535A (zh) 2015-10-07
CA2680863C (en) 2012-05-29
MY151041A (en) 2014-03-31
EP2141229A1 (en) 2010-01-06
DK2141229T3 (en) 2015-08-03
RU2009138225A (ru) 2011-04-27
EP2141229A4 (en) 2010-06-02

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