UA97257C2 - Indole derivatives - Google Patents

Indole derivatives

Info

Publication number
UA97257C2
UA97257C2 UAA200904957A UAA200904957A UA97257C2 UA 97257 C2 UA97257 C2 UA 97257C2 UA A200904957 A UAA200904957 A UA A200904957A UA A200904957 A UAA200904957 A UA A200904957A UA 97257 C2 UA97257 C2 UA 97257C2
Authority
UA
Ukraine
Prior art keywords
indole derivatives
ris
present
glucokinase activator
agent
Prior art date
Application number
UAA200904957A
Other languages
English (en)
Ukrainian (uk)
Inventor
Цунео Ясума
Осаму Уджикава
Масахиро ИТОХ
Казуко АОКИ
Original Assignee
Такеда Фармасьютикал Компани Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39010108&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA97257(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Такеда Фармасьютикал Компани Лимитед filed Critical Такеда Фармасьютикал Компани Лимитед
Publication of UA97257C2 publication Critical patent/UA97257C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/433Thidiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Данное изобретение касается соединения, которое представлено формулой (I):, (I)гдеRявляется атомом водорода или атомом галогена;Rявляется группой,которая является активатором глюкокиназы, а также фармацевтической композиции на его основе как средства для профилактики или лечения диабета, ожирения, и т.п.
UAA200904957A 2006-10-19 2007-10-18 Indole derivatives UA97257C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006285551 2006-10-19
PCT/JP2007/070772 WO2008050821A1 (en) 2006-10-19 2007-10-18 Indole compound

Publications (1)

Publication Number Publication Date
UA97257C2 true UA97257C2 (en) 2012-01-25

Family

ID=39010108

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200904957A UA97257C2 (en) 2006-10-19 2007-10-18 Indole derivatives

Country Status (26)

Country Link
US (4) US8410087B2 (ru)
EP (2) EP2074119A1 (ru)
JP (1) JP5260507B2 (ru)
KR (1) KR101444486B1 (ru)
CN (1) CN101573357B (ru)
AU (1) AU2007310064B2 (ru)
BR (1) BRPI0717722A2 (ru)
CA (1) CA2666973C (ru)
CL (1) CL2008001017A1 (ru)
CR (1) CR10748A (ru)
EC (1) ECSP099330A (ru)
GE (1) GEP20115241B (ru)
IL (1) IL198154A (ru)
MA (1) MA30890B1 (ru)
ME (1) ME00681B (ru)
MX (1) MX2009003972A (ru)
MY (1) MY158052A (ru)
NO (1) NO20091948L (ru)
NZ (1) NZ576570A (ru)
PE (1) PE20090884A1 (ru)
RU (1) RU2454415C9 (ru)
TN (1) TN2009000129A1 (ru)
TW (1) TWI460176B (ru)
UA (1) UA97257C2 (ru)
WO (1) WO2008050821A1 (ru)
ZA (1) ZA200902585B (ru)

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Also Published As

Publication number Publication date
US7718798B2 (en) 2010-05-18
CA2666973A1 (en) 2008-05-02
MEP11809A (en) 2011-12-20
NZ576570A (en) 2010-11-26
EP2074119A1 (en) 2009-07-01
KR20090068292A (ko) 2009-06-25
ZA200902585B (en) 2010-09-29
AU2007310064B2 (en) 2013-03-28
AU2007310064A2 (en) 2009-06-04
CA2666973C (en) 2015-03-31
US8410087B2 (en) 2013-04-02
CN101573357B (zh) 2013-01-23
RU2454415C2 (ru) 2012-06-27
ME00681B (me) 2011-12-20
GEP20115241B (en) 2011-06-10
US7652133B2 (en) 2010-01-26
US20090286975A1 (en) 2009-11-19
US20080096877A1 (en) 2008-04-24
US7777047B2 (en) 2010-08-17
RU2454415C9 (ru) 2013-02-27
TN2009000129A1 (en) 2010-10-18
BRPI0717722A2 (pt) 2013-10-29
MA30890B1 (fr) 2009-11-02
CR10748A (es) 2009-05-20
CN101573357A (zh) 2009-11-04
IL198154A (en) 2014-08-31
CL2008001017A1 (es) 2009-04-24
IL198154A0 (en) 2009-12-24
US20100144702A1 (en) 2010-06-10
MX2009003972A (es) 2009-04-27
TW200825071A (en) 2008-06-16
JP5260507B2 (ja) 2013-08-14
PE20090884A1 (es) 2009-08-05
AU2007310064A1 (en) 2008-05-02
EP2508524A3 (en) 2012-10-24
TWI460176B (zh) 2014-11-11
ECSP099330A (es) 2009-06-30
MY158052A (en) 2016-08-30
JP2010506825A (ja) 2010-03-04
RU2009118602A (ru) 2010-11-27
US20100137610A1 (en) 2010-06-03
EP2508524A2 (en) 2012-10-10
WO2008050821A1 (en) 2008-05-02
KR101444486B1 (ko) 2014-09-24
NO20091948L (no) 2009-07-13

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