SV2017005478A - Sal de tosilato n-[3-[(4ar,7as)-2-amino-6-(5-fluoropirimidina-2-il)-4,4a,5,7-tetrahidropirrolo[3,4-d][1,3]tiazina-7a-il]-4-fluoro-fenil]-5-metoxi-pirazina-2-carboxamida - Google Patents
Sal de tosilato n-[3-[(4ar,7as)-2-amino-6-(5-fluoropirimidina-2-il)-4,4a,5,7-tetrahidropirrolo[3,4-d][1,3]tiazina-7a-il]-4-fluoro-fenil]-5-metoxi-pirazina-2-carboxamidaInfo
- Publication number
- SV2017005478A SV2017005478A SV2017005478A SV2017005478A SV2017005478A SV 2017005478 A SV2017005478 A SV 2017005478A SV 2017005478 A SV2017005478 A SV 2017005478A SV 2017005478 A SV2017005478 A SV 2017005478A SV 2017005478 A SV2017005478 A SV 2017005478A
- Authority
- SV
- El Salvador
- Prior art keywords
- tetrahydropirrolo
- pirazina
- carboxamida
- metoxi
- fluoro
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A UNA 10 SAL DE TOSILATO DE N-[3-[(4AR,7AS)-2-AMINO-6-(5-FLUOROPIRIMIDIN-2-IL)-4,4A,5,7-TETRAHIDROPIRROLO[3,4-D][1,3]TIAZIN-7A-IL]-4-FLUORO-FENIL]-5-METOXI-PIRAZINA-2-CARBOXAMIDA
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562109733P | 2015-01-30 | 2015-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SV2017005478A true SV2017005478A (es) | 2018-02-09 |
Family
ID=55275232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SV2017005478A SV2017005478A (es) | 2015-01-30 | 2017-07-06 | Sal de tosilato n-[3-[(4ar,7as)-2-amino-6-(5-fluoropirimidina-2-il)-4,4a,5,7-tetrahidropirrolo[3,4-d][1,3]tiazina-7a-il]-4-fluoro-fenil]-5-metoxi-pirazina-2-carboxamida |
Country Status (41)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR103406A1 (es) * | 2015-01-30 | 2017-05-10 | Lilly Co Eli | Sal de tosilato |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT401651B (de) * | 1994-06-14 | 1996-11-25 | Biochemie Gmbh | 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroximinoacetamido)-3-n,n- dimethylcarbamoyloxymethyl-3-cephem-4- |
| NZ585671A (en) * | 2007-12-07 | 2012-06-29 | Pfizer | Tosylate salt of trans-n-isobutyl-3-fluoro-3- [3-fluoro-4- (pyrrolidin-1-yl-methyl) -phenyl] cyclobut anecarboxamide |
| EP2233474B1 (en) * | 2008-01-18 | 2015-08-05 | Eisai R&D Management Co., Ltd. | Condensed aminodihydrothiazine derivative |
| TWI593692B (zh) * | 2013-03-12 | 2017-08-01 | 美國禮來大藥廠 | 四氫吡咯并噻嗪化合物 |
| TWI570127B (zh) * | 2014-09-15 | 2017-02-11 | 美國禮來大藥廠 | 結晶型N-[3-[(4aR,7aS)-2-胺基-6-(5-氟嘧啶-2-基)-4,4a,5,7-四氫吡咯并[3,4-d][1,3]噻嗪-7a-基]-4-氟-苯基]-5-甲氧基-吡嗪-2-甲醯胺、其用途及醫藥組合物 |
| AR103406A1 (es) * | 2015-01-30 | 2017-05-10 | Lilly Co Eli | Sal de tosilato |
-
2016
- 2016-01-13 AR ARP160100076A patent/AR103406A1/es unknown
- 2016-01-13 TW TW105100973A patent/TWI574969B/zh not_active IP Right Cessation
- 2016-01-22 PT PT167026541T patent/PT3250575T/pt unknown
- 2016-01-22 RS RS20191663A patent/RS59730B1/sr unknown
- 2016-01-22 MA MA41420A patent/MA41420B1/fr unknown
- 2016-01-22 AU AU2016211827A patent/AU2016211827B2/en not_active Ceased
- 2016-01-22 CA CA2969475A patent/CA2969475C/en not_active Expired - Fee Related
- 2016-01-22 JP JP2017540253A patent/JP6723250B2/ja active Active
- 2016-01-22 MX MX2017009713A patent/MX2017009713A/es unknown
- 2016-01-22 US US15/535,523 patent/US10080758B2/en active Active
- 2016-01-22 CR CR20170287A patent/CR20170287A/es unknown
- 2016-01-22 LT LTEP16702654.1T patent/LT3250575T/lt unknown
- 2016-01-22 DK DK16702654.1T patent/DK3250575T3/da active
- 2016-01-22 ME MEP-2019-347A patent/ME03581B/me unknown
- 2016-01-22 WO PCT/US2016/014423 patent/WO2016122968A1/en active Application Filing
- 2016-01-22 TN TNP/2017/000332A patent/TN2017000332A1/en unknown
- 2016-01-22 KR KR1020177020943A patent/KR101950129B1/ko active IP Right Grant
- 2016-01-22 SG SG11201706038PA patent/SG11201706038PA/en unknown
- 2016-01-22 SI SI201630517T patent/SI3250575T1/sl unknown
- 2016-01-22 CN CN201680005234.2A patent/CN107108657B/zh active Active
- 2016-01-22 EA EA201791229A patent/EA031330B1/ru not_active IP Right Cessation
- 2016-01-22 HU HUE16702654A patent/HUE048029T2/hu unknown
- 2016-01-22 MD MDE20170309T patent/MD3250575T2/ro unknown
- 2016-01-22 EP EP16702654.1A patent/EP3250575B1/en active Active
- 2016-01-22 ES ES16702654T patent/ES2768782T3/es active Active
- 2016-01-22 PE PE2017001211A patent/PE20171333A1/es unknown
- 2016-01-22 BR BR112017012149-2A patent/BR112017012149A2/pt not_active Application Discontinuation
- 2016-01-22 UA UAA201707108A patent/UA119581C2/uk unknown
- 2016-01-22 PL PL16702654T patent/PL3250575T3/pl unknown
- 2016-01-22 NZ NZ732381A patent/NZ732381A/en not_active IP Right Cessation
-
2017
- 2017-06-07 IL IL252754A patent/IL252754A0/en unknown
- 2017-06-08 ZA ZA2017/03937A patent/ZA201703937B/en unknown
- 2017-07-03 DO DO2017000159A patent/DOP2017000159A/es unknown
- 2017-07-06 SV SV2017005478A patent/SV2017005478A/es unknown
- 2017-07-25 CL CL2017001899A patent/CL2017001899A1/es unknown
- 2017-07-27 GT GT201700166A patent/GT201700166A/es unknown
- 2017-07-28 PH PH12017501356A patent/PH12017501356A1/en unknown
- 2017-07-28 EC ECIEPI201748768A patent/ECSP17048768A/es unknown
- 2017-08-01 CO CONC2017/0007810A patent/CO2017007810A2/es unknown
-
2019
- 2019-04-10 JP JP2019074951A patent/JP2019142902A/ja not_active Ceased
- 2019-12-12 HR HRP20192240TT patent/HRP20192240T1/hr unknown
-
2020
- 2020-01-15 CY CY20201100033T patent/CY1122548T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA42990A (fr) | Composés utiles en tant qu'immunomodulateurs | |
| AR101995A1 (es) | COMPUESTOS ANTAGONISTAS DE INTEGRINA avb6 | |
| MA40587A (fr) | Composés d'aminopyrimidinyle en tant qu'inhibiteurs de jak | |
| EA201790407A1 (ru) | Зонды для визуализации белка хантингтина | |
| CR20150418A (es) | Compuestos de tetrahidropirrolotiazina | |
| BR112016026942A2 (pt) | geração de visualizações de direção curva por curva. | |
| TR201906366T4 (tr) | Polisiklik-karbamoilpiridon bileşiklerinin sentezi. | |
| BR112017013936A2 (pt) | inibidores de bace1 seletivos. | |
| MA46180A (fr) | Analogues de l'amyline | |
| MA46878A (fr) | Composés de benzodiazolium en tant qu'inhibiteurs d'enac | |
| AR095097A1 (es) | Compuestos de fenoxietoxi | |
| EA201790400A1 (ru) | Зонды для визуализации белка хантингтина | |
| SV2017005478A (es) | Sal de tosilato n-[3-[(4ar,7as)-2-amino-6-(5-fluoropirimidina-2-il)-4,4a,5,7-tetrahidropirrolo[3,4-d][1,3]tiazina-7a-il]-4-fluoro-fenil]-5-metoxi-pirazina-2-carboxamida | |
| CL2017000645A1 (es) | Síntesis de ent-progesterona e intermediarios de la misma | |
| CO2017010725A2 (es) | N-[3-[(4as,5s,7as)-2-amino-5-(1,1-difluoroetil)-4,4a,5,7-tetrahidrofuro[3,4-d][1,3]tiazin-7a-il]-4-fluoro-fenil]-5-ciano-2-picolamida, su sal metanosulfonato y una forma cristalina hemihidrato de la sal 4-metilbencenosulfonato del mismo, composiciones que los contienen y procedimientos para su elaboración | |
| CO2017001927A2 (es) | Formas cristalinas de n-[3-[(4ar,7as)-2-amino-6-(5- fluoropirimidin-2-il)-4,4a,5,7-tetrahidropirrolo[3,4-d][1,3]tiazin-7a-il]-4-fluoro-fenil]-5-metoxi-pirazin-2-carboxamida como inhibidores de bace | |
| DOP2017000016A (es) | Nueva sal de disoproxilo de tenofovir | |
| TH182870B (th) | เกลือทอซิเลทของ n-[3-[(4ar,7as)-2-อะมิโน-6-(5-ฟลูออโรพิริมิดิน-2-อิล)-4,4a,5,7-เททระไฮโดรพิร์โรโล[3,4-d][1,3]ไธอะซิน-7a-อิล]-4-ฟลูออโร-เฟนิล]-5-เมธอกซิ-ไพแรซีน-2-คาร์บอกแซมีด | |
| MA53299A (fr) | Composés de thiazolo-pyridine substitués en tant qu'inhibiteurs de malt1 | |
| DK3426641T3 (da) | Immunoproteasominhibitoranaloger | |
| KR20160023503A (ko) | 갑각류피자 | |
| TH1601002537A (th) | กระบวนการสำหรับการสังเคราะห์สารยับยั้งอินโดลเอมีน 2,3-ไดออกซีจีเนสชนิดหนึ่ง |