GT201700166A - Sal de tosilato - Google Patents
Sal de tosilatoInfo
- Publication number
- GT201700166A GT201700166A GT201700166A GT201700166A GT201700166A GT 201700166 A GT201700166 A GT 201700166A GT 201700166 A GT201700166 A GT 201700166A GT 201700166 A GT201700166 A GT 201700166A GT 201700166 A GT201700166 A GT 201700166A
- Authority
- GT
- Guatemala
- Prior art keywords
- tosilate
- salt
- tosilate salt
- tetrahydropirrolo
- fluoropirimidin
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
LA PRESENTE INVENCIÓN SE REFIERE A UNA SAL DE TOSILATO DE N- [3-[(4AR, 7AS)-2-AMINO-6-(5-FLUOROPIRIMIDIN-2-IL)-4, 4A, 5, 7-TETRAHIDROPIRROLO [3,4-D] [1,3] TIAZIN-7A-IL]-4-FLUORO-FENIL]-5-METOXI-PIRAZINA-2-CARBOXAMIDA.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562109733P | 2015-01-30 | 2015-01-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GT201700166A true GT201700166A (es) | 2018-11-23 |
Family
ID=55275232
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GT201700166A GT201700166A (es) | 2015-01-30 | 2017-07-27 | Sal de tosilato |
Country Status (41)
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI574969B (zh) * | 2015-01-30 | 2017-03-21 | 美國禮來大藥廠 | 甲苯磺酸鹽 |
| WO2019094608A1 (en) | 2017-11-08 | 2019-05-16 | Denali Therapeutics Inc. | Anti-bace1 antibodies and methods of use thereof |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT401651B (de) * | 1994-06-14 | 1996-11-25 | Biochemie Gmbh | 7-(2-(2-aminothiazol-4-yl)-2-(z)- hydroximinoacetamido)-3-n,n- dimethylcarbamoyloxymethyl-3-cephem-4- |
| RU2451016C2 (ru) * | 2007-12-07 | 2012-05-20 | Пфайзер Инк. | Тозилатная соль транс-n-изобутил-3-фтор-3-[3-фтор-4-(пирролидин-1-илметил)фенил]циклобутанкарбоксамида |
| KR101564634B1 (ko) * | 2008-01-18 | 2015-10-30 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 축합 아미노디하이드로 티아진 유도체 |
| TWI593692B (zh) | 2013-03-12 | 2017-08-01 | 美國禮來大藥廠 | 四氫吡咯并噻嗪化合物 |
| TWI570127B (zh) * | 2014-09-15 | 2017-02-11 | 美國禮來大藥廠 | 結晶型N-[3-[(4aR,7aS)-2-胺基-6-(5-氟嘧啶-2-基)-4,4a,5,7-四氫吡咯并[3,4-d][1,3]噻嗪-7a-基]-4-氟-苯基]-5-甲氧基-吡嗪-2-甲醯胺、其用途及醫藥組合物 |
| TWI574969B (zh) * | 2015-01-30 | 2017-03-21 | 美國禮來大藥廠 | 甲苯磺酸鹽 |
-
2016
- 2016-01-13 TW TW105100973A patent/TWI574969B/zh not_active IP Right Cessation
- 2016-01-13 AR ARP160100076A patent/AR103406A1/es unknown
- 2016-01-22 TN TNP/2017/000332A patent/TN2017000332A1/en unknown
- 2016-01-22 ES ES16702654T patent/ES2768782T3/es active Active
- 2016-01-22 SI SI201630517T patent/SI3250575T1/sl unknown
- 2016-01-22 HU HUE16702654A patent/HUE048029T2/hu unknown
- 2016-01-22 LT LTEP16702654.1T patent/LT3250575T/lt unknown
- 2016-01-22 RS RS20191663A patent/RS59730B1/sr unknown
- 2016-01-22 EA EA201791229A patent/EA031330B1/ru not_active IP Right Cessation
- 2016-01-22 CA CA2969475A patent/CA2969475C/en not_active Expired - Fee Related
- 2016-01-22 MD MDE20170309T patent/MD3250575T2/ro unknown
- 2016-01-22 US US15/535,523 patent/US10080758B2/en active Active
- 2016-01-22 MX MX2017009713A patent/MX2017009713A/es unknown
- 2016-01-22 KR KR1020177020943A patent/KR101950129B1/ko active IP Right Grant
- 2016-01-22 PT PT167026541T patent/PT3250575T/pt unknown
- 2016-01-22 CR CR20170287A patent/CR20170287A/es unknown
- 2016-01-22 AU AU2016211827A patent/AU2016211827B2/en not_active Ceased
- 2016-01-22 MA MA41420A patent/MA41420B1/fr unknown
- 2016-01-22 BR BR112017012149-2A patent/BR112017012149A2/pt not_active Application Discontinuation
- 2016-01-22 DK DK16702654.1T patent/DK3250575T3/da active
- 2016-01-22 NZ NZ732381A patent/NZ732381A/en not_active IP Right Cessation
- 2016-01-22 PL PL16702654T patent/PL3250575T3/pl unknown
- 2016-01-22 CN CN201680005234.2A patent/CN107108657B/zh active Active
- 2016-01-22 ME MEP-2019-347A patent/ME03581B/me unknown
- 2016-01-22 WO PCT/US2016/014423 patent/WO2016122968A1/en active Application Filing
- 2016-01-22 UA UAA201707108A patent/UA119581C2/uk unknown
- 2016-01-22 EP EP16702654.1A patent/EP3250575B1/en active Active
- 2016-01-22 SG SG11201706038PA patent/SG11201706038PA/en unknown
- 2016-01-22 PE PE2017001211A patent/PE20171333A1/es unknown
- 2016-01-22 JP JP2017540253A patent/JP6723250B2/ja active Active
-
2017
- 2017-06-07 IL IL252754A patent/IL252754A0/en unknown
- 2017-06-08 ZA ZA2017/03937A patent/ZA201703937B/en unknown
- 2017-07-03 DO DO2017000159A patent/DOP2017000159A/es unknown
- 2017-07-06 SV SV2017005478A patent/SV2017005478A/es unknown
- 2017-07-25 CL CL2017001899A patent/CL2017001899A1/es unknown
- 2017-07-27 GT GT201700166A patent/GT201700166A/es unknown
- 2017-07-28 EC ECIEPI201748768A patent/ECSP17048768A/es unknown
- 2017-07-28 PH PH12017501356A patent/PH12017501356A1/en unknown
- 2017-08-01 CO CONC2017/0007810A patent/CO2017007810A2/es unknown
-
2019
- 2019-04-10 JP JP2019074951A patent/JP2019142902A/ja not_active Ceased
- 2019-12-12 HR HRP20192240TT patent/HRP20192240T1/hr unknown
-
2020
- 2020-01-15 CY CY20201100033T patent/CY1122548T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR101995A1 (es) | COMPUESTOS ANTAGONISTAS DE INTEGRINA avb6 | |
| TR201905829T4 (tr) | Buzdolabı. | |
| EA201790407A1 (ru) | Зонды для визуализации белка хантингтина | |
| BR112016026942A2 (pt) | geração de visualizações de direção curva por curva. | |
| CR20170315A (es) | Inhibridores bace 1 selectivos | |
| EA201790400A1 (ru) | Зонды для визуализации белка хантингтина | |
| AR095097A1 (es) | Compuestos de fenoxietoxi | |
| UY4430S (es) | “motocicleta”. | |
| GT201700166A (es) | Sal de tosilato | |
| CL2017000645A1 (es) | Síntesis de ent-progesterona e intermediarios de la misma | |
| CO2017001927A2 (es) | Formas cristalinas de n-[3-[(4ar,7as)-2-amino-6-(5- fluoropirimidin-2-il)-4,4a,5,7-tetrahidropirrolo[3,4-d][1,3]tiazin-7a-il]-4-fluoro-fenil]-5-metoxi-pirazin-2-carboxamida como inhibidores de bace | |
| DOP2017000016A (es) | Nueva sal de disoproxilo de tenofovir | |
| TH182870B (th) | เกลือทอซิเลทของ n-[3-[(4ar,7as)-2-อะมิโน-6-(5-ฟลูออโรพิริมิดิน-2-อิล)-4,4a,5,7-เททระไฮโดรพิร์โรโล[3,4-d][1,3]ไธอะซิน-7a-อิล]-4-ฟลูออโร-เฟนิล]-5-เมธอกซิ-ไพแรซีน-2-คาร์บอกแซมีด | |
| ГЕПАТИТА et al. | 112∎ MATERIALS OF CONFERENCES∎ | |
| KR20160023503A (ko) | 갑각류피자 | |
| UA112287U (xx) | Застосування вінборону для нівелювання антипроліферативного впливу ібупрофену на шлунковий епітелій | |
| ECSDI15050234S (es) | Motocicleta | |
| ECSDI15046482S (es) | Motocicleta | |
| TH1601000900A (th) | สารประกอบซึ่งถูกแทนที่ด้วยควิโนลีนชนิดใหม่ | |
| TR201401768A2 (tr) | Miyasteninin tedavisine yönelik bir kompozisyon. | |
| UA93238U (uk) | Комплексний препарат "глуцисаргін" | |
| TH1601005811B (th) | โครงสร้างส่วนประดับด้านหน้าของรถจักรยานยนต์ | |
| UA92398U (en) | Biting signalizer | |
| UA93524U (uk) | 5-(феноксиметил)-4-феніл-4н-1,2,4-триазол-3-тіол, що проявляє жарознижуючу активність | |
| RU2012143236A (ru) | Рукав-голинище |