PT902783E - Derivados hidrofobicos do taxano que promovem hidrolise - Google Patents

Derivados hidrofobicos do taxano que promovem hidrolise

Info

Publication number
PT902783E
PT902783E PT96930847T PT96930847T PT902783E PT 902783 E PT902783 E PT 902783E PT 96930847 T PT96930847 T PT 96930847T PT 96930847 T PT96930847 T PT 96930847T PT 902783 E PT902783 E PT 902783E
Authority
PT
Portugal
Prior art keywords
taxane
hydrocarbon
taxano
hydrolysis
hpg
Prior art date
Application number
PT96930847T
Other languages
English (en)
Inventor
Eric Mayhew
Shaukat Ali
Andrew S Janoff
Original Assignee
Elan Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Elan Pharm Inc filed Critical Elan Pharm Inc
Publication of PT902783E publication Critical patent/PT902783E/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
PT96930847T 1995-09-12 1996-09-12 Derivados hidrofobicos do taxano que promovem hidrolise PT902783E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US357595P 1995-09-12 1995-09-12

Publications (1)

Publication Number Publication Date
PT902783E true PT902783E (pt) 2002-09-30

Family

ID=21706522

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96930847T PT902783E (pt) 1995-09-12 1996-09-12 Derivados hidrofobicos do taxano que promovem hidrolise

Country Status (22)

Country Link
US (1) US5703117A (pt)
EP (1) EP0902783B1 (pt)
JP (1) JP4192208B2 (pt)
KR (1) KR100401220B1 (pt)
CN (1) CN1100770C (pt)
AT (2) ATE216377T1 (pt)
CA (1) CA2231750C (pt)
CZ (1) CZ288562B6 (pt)
DE (2) DE69635428T2 (pt)
DK (2) DK0902783T3 (pt)
ES (2) ES2179208T3 (pt)
HK (1) HK1016169A1 (pt)
HU (1) HU226325B1 (pt)
IL (1) IL123595A (pt)
MX (1) MX9801871A (pt)
NO (1) NO319521B1 (pt)
NZ (1) NZ318300A (pt)
PL (1) PL187738B1 (pt)
PT (1) PT902783E (pt)
SK (1) SK283199B6 (pt)
TR (1) TR199800443T1 (pt)
WO (1) WO1997010234A1 (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6107332A (en) * 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6667053B1 (en) * 1996-02-16 2003-12-23 Elan Pharmaceuticals, Inc. D and L etherlipid stereoisomers and liposomes
US5912264A (en) * 1997-03-03 1999-06-15 Bristol-Myers Squibb Company 6-halo-or nitrate-substituted paclitaxels
US8853260B2 (en) 1997-06-27 2014-10-07 Abraxis Bioscience, Llc Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
ES2399480T3 (es) * 1997-11-10 2013-04-01 Memorial Sloan-Kettering Cancer Center Procedimiento de producción de formulaciones de trióxido de arsénico
SK17422000A3 (sk) * 1998-05-20 2001-09-11 The Liposome Company, Inc. Kompozöcie ¬astöc
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6146659A (en) * 1998-07-01 2000-11-14 Neopharm, Inc. Method of administering liposomal encapsulated taxane
AU775875B2 (en) * 1999-01-12 2004-08-19 Quanam Medical Corporation Composition and methods for administration of water-insoluble paclitaxel derivatives
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
CA2410632A1 (en) 2000-06-22 2001-12-27 David S. Garvey Nitrosated and nitrosylated taxanes, compositions and methods of use
US6607689B1 (en) * 2000-08-29 2003-08-19 Micron Technology, Inc. Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length
DE60137229D1 (de) * 2001-10-22 2009-02-12 Viroblock Sa Non-phospholipid Vesikel (npLV) und ihre Verwendung in kosmetischen, therapeutischen und prophylaktischen Anwendungen
JP2005515187A (ja) * 2001-11-26 2005-05-26 スーパージェン インコーポレイテッド ポリオキシエチル化ひまし油を使用する医薬組成物の調製方法
AU2003249882B2 (en) * 2002-06-26 2008-09-18 Medigene Ag Novel method of stabilizing diagnostic and therapeutic compounds in a cationic carrier system
EP1596825A2 (en) 2003-02-03 2005-11-23 Neopharm, Inc. Stable sterile filterable liposomal encapsulated taxane and other antineoplastic drugs
CN101146514B (zh) * 2005-02-18 2013-03-27 阿布拉西斯生物科学公司 用于整合入医疗装置的疏水性改善的药物
CA2603987A1 (en) 2005-04-12 2006-10-19 Wisconsin Alumni Research Foundation Micelle composition of polymer and passenger drug
KR20100133475A (ko) * 2008-04-10 2010-12-21 아브락시스 바이오사이언스, 엘엘씨 소수성 탁산 유도체의 조성물 그의 용도
WO2009126401A1 (en) * 2008-04-10 2009-10-15 Abraxis Bioscience, Llc Compositions of hydrophobic taxane derivatives and uses thereof
WO2011038278A2 (en) 2009-09-25 2011-03-31 Wisconsin Alumni Research Foundation Micelle encapsulation of therapeutic agents
CN105503844A (zh) * 2015-12-11 2016-04-20 上海大学 C-13和c-7位结构改造的紫杉醇类化合物及其制备方法
CN111004195B (zh) * 2019-12-03 2022-01-28 沈阳药科大学 卡巴他赛弱碱性衍生物及其制剂

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
US5059699A (en) * 1990-08-28 1991-10-22 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
CA2119261C (en) * 1992-12-23 2006-01-31 Michael A. Poss Novel sidechain-bearing taxanes and intermediates thereof
IL108316A (en) * 1993-01-15 2006-10-31 Univ Florida State History of C-10 Texan and pharmaceuticals containing them
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives

Also Published As

Publication number Publication date
HK1016169A1 (en) 1999-10-29
EP0902783B1 (en) 2002-04-17
JP4192208B2 (ja) 2008-12-10
CZ288562B6 (cs) 2001-07-11
KR100401220B1 (ko) 2004-03-20
DE69635428T2 (de) 2006-06-14
WO1997010234A1 (en) 1997-03-20
CN1100770C (zh) 2003-02-05
CA2231750C (en) 2006-07-11
AU706290B2 (en) 1999-06-10
HUP9901433A3 (en) 2001-05-28
SK33498A3 (en) 1998-08-05
MX9801871A (es) 1998-05-31
CZ71198A3 (cs) 1998-07-15
PL187738B1 (pl) 2004-09-30
DE69635428D1 (de) 2005-12-15
ES2179208T3 (es) 2003-01-16
TR199800443T1 (xx) 1998-06-22
DK0902783T3 (da) 2002-07-22
ES2252347T3 (es) 2006-05-16
EP0902783A4 (pt) 1999-03-24
AU6975696A (en) 1997-04-01
IL123595A0 (en) 1998-10-30
NO981071L (no) 1998-05-12
SK283199B6 (sk) 2003-03-04
DE69620802D1 (de) 2002-05-23
NZ318300A (en) 1999-08-30
US5703117A (en) 1997-12-30
IL123595A (en) 2000-10-31
KR19990044409A (ko) 1999-06-25
DK1229030T3 (da) 2006-02-13
JP2001519755A (ja) 2001-10-23
NO981071D0 (no) 1998-03-11
PL325477A1 (en) 1998-07-20
EP0902783A1 (en) 1999-03-24
HU226325B1 (en) 2008-08-28
ATE309235T1 (de) 2005-11-15
NO319521B1 (no) 2005-08-22
CN1202166A (zh) 1998-12-16
CA2231750A1 (en) 1997-03-20
ATE216377T1 (de) 2002-05-15
HUP9901433A2 (hu) 2001-04-28
DE69620802T2 (de) 2002-10-10

Similar Documents

Publication Publication Date Title
PT902783E (pt) Derivados hidrofobicos do taxano que promovem hidrolise
DE69713526D1 (de) Lösliche prodrugs von paclitaxel
MX9603479A (es) Derivados de 4-amino de acido micofenolico con actividad inmunosupresora.
PT1063234E (pt) Derivados de taxano hidrofobos
CA2301057A1 (en) A method of administering liposomal encapsulated taxane
FI935394A0 (fi) Foerbaettringar i betraeffande kontrastmedel
ATE297726T1 (de) Forskolin zur entwicklung magerer körpermasse
ATE324119T1 (de) Verwendung von saccharid-konjugaten
CY1109695T1 (el) Μικροοργανισμοι αποδομησης οξαλικου ή ενζυμα αποδομησης οξαλικου για την προληψη παθησης σχετιζομενης με οξαλικο
SE8404283D0 (sv) Anvendning av ett specifikt tumorassocierat antigen, nemligen sialosyllaktotetraos, for diagnostiska och terapeutiska forfaranden vid cancersjukdomar
BR0015149A (pt) Método e composições para administração de taxanos oralmente a pacientes humanos
NO20050216L (no) Steroidkonjugater samt fremstilling og anvendelse derav
ES2038642T3 (es) Tratamiento dermico de enfermedades vermiculares del gato con pracicuantel.
ATE141796T1 (de) 2',5'-oligoadenylat-derivate zur verwendung als heilmittel
EP1229030A3 (en) Hydrolysis-promoting taxane hydrophobic derivates
BR0014687A (pt) Compostos de taxano pentacìclico
CO4340732A1 (es) 4-amino-derivados del acido micofenolico 5-substituido
ES8605989A1 (es) Un metodo de preparar un complejo de fibronectina, dextrano y farmaco
HUP0004647A2 (hu) Glükóz-amino-glükánok alkalmazása diabétesszel társult szembetegségek kezelésére szolgáló gyógyszerkészítmények előállítására
MX9603483A (es) Acido micofenolico 6-sustituido y derivados.
IT8620514V0 (it) Struttura di cannula vaginale monouso, per l'applicazione di pomate, medicamenti semidensi e simili.
MX9709684A (es) Uso de derivados de vitamina d4 para tratamiento de trastornos de la piel.
UA15177C2 (uk) Засіб для лікуваhhя уражеhь слизової травhого тракту