ATE309235T1 - Hydrolyse-einleitende hydrophobe taxane derivate - Google Patents
Hydrolyse-einleitende hydrophobe taxane derivateInfo
- Publication number
- ATE309235T1 ATE309235T1 AT02008590T AT02008590T ATE309235T1 AT E309235 T1 ATE309235 T1 AT E309235T1 AT 02008590 T AT02008590 T AT 02008590T AT 02008590 T AT02008590 T AT 02008590T AT E309235 T1 ATE309235 T1 AT E309235T1
- Authority
- AT
- Austria
- Prior art keywords
- hydrolysis
- taxane
- hydrocarbon
- initiation
- taxane derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US357595P | 1995-09-12 | 1995-09-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE309235T1 true ATE309235T1 (de) | 2005-11-15 |
Family
ID=21706522
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96930847T ATE216377T1 (de) | 1995-09-12 | 1996-09-12 | Hydrolysierbare hydrophobe taxanderivate |
AT02008590T ATE309235T1 (de) | 1995-09-12 | 1996-09-12 | Hydrolyse-einleitende hydrophobe taxane derivate |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96930847T ATE216377T1 (de) | 1995-09-12 | 1996-09-12 | Hydrolysierbare hydrophobe taxanderivate |
Country Status (22)
Country | Link |
---|---|
US (1) | US5703117A (de) |
EP (1) | EP0902783B1 (de) |
JP (1) | JP4192208B2 (de) |
KR (1) | KR100401220B1 (de) |
CN (1) | CN1100770C (de) |
AT (2) | ATE216377T1 (de) |
CA (1) | CA2231750C (de) |
CZ (1) | CZ288562B6 (de) |
DE (2) | DE69620802T2 (de) |
DK (2) | DK1229030T3 (de) |
ES (2) | ES2252347T3 (de) |
HK (1) | HK1016169A1 (de) |
HU (1) | HU226325B1 (de) |
IL (1) | IL123595A (de) |
MX (1) | MX9801871A (de) |
NO (1) | NO319521B1 (de) |
NZ (1) | NZ318300A (de) |
PL (1) | PL187738B1 (de) |
PT (1) | PT902783E (de) |
SK (1) | SK283199B6 (de) |
TR (1) | TR199800443T1 (de) |
WO (1) | WO1997010234A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6107332A (en) * | 1995-09-12 | 2000-08-22 | The Liposome Company, Inc. | Hydrolysis-promoting hydrophobic taxane derivatives |
US6667053B1 (en) * | 1996-02-16 | 2003-12-23 | Elan Pharmaceuticals, Inc. | D and L etherlipid stereoisomers and liposomes |
US5912264A (en) * | 1997-03-03 | 1999-06-15 | Bristol-Myers Squibb Company | 6-halo-or nitrate-substituted paclitaxels |
US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
AU747474C (en) | 1997-11-10 | 2006-09-21 | Memorial Sloan-Kettering Cancer Center | Process for producing arsenic trioxide formulations and methods for treating cancer using arsenic trioxide or melarsoprol |
KR20010052368A (ko) * | 1998-05-20 | 2001-06-25 | 질레스피 카롤 | 신규한 입자 제형 |
US7314637B1 (en) | 1999-06-29 | 2008-01-01 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
US6146659A (en) * | 1998-07-01 | 2000-11-14 | Neopharm, Inc. | Method of administering liposomal encapsulated taxane |
JP2002534461A (ja) * | 1999-01-12 | 2002-10-15 | クアナム メディカル コーポレイション | 水不溶性のパクリタキセル誘導体の投与のための組成物および方法 |
CA2385528C (en) | 1999-10-01 | 2013-12-10 | Immunogen, Inc. | Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents |
US6656966B2 (en) | 2000-06-22 | 2003-12-02 | Nitromed, Inc. | Nitrosated and nitrosylated taxanes, compositions and methods of use |
US6607689B1 (en) * | 2000-08-29 | 2003-08-19 | Micron Technology, Inc. | Layer thickness control for stereolithography utilizing variable liquid elevation and laser focal length |
EP1304103B1 (de) * | 2001-10-22 | 2008-12-31 | Viroblock SA | Non-phospholipid Vesikel (npLV) und ihre Verwendung in kosmetischen, therapeutischen und prophylaktischen Anwendungen |
US6710195B2 (en) * | 2001-11-26 | 2004-03-23 | Supergen, Inc. | Method for preparing and using polyoxyethylated castor oil in pharmaceutical compositions |
DE60335279D1 (de) * | 2002-06-26 | 2011-01-20 | Medigene Ag | Neues verfahren zur stabilisierung von diagnostischen und therapeutischen verbindungen in einem kationischen trägersystem |
EA200501252A1 (ru) | 2003-02-03 | 2006-02-24 | Неофарм, Инк. | Липосомальная композиция, способ ее получения и лекарственное средство на ее основе (варианты) |
EP1861070B1 (de) * | 2005-02-18 | 2018-01-17 | Abraxis BioScience, LLC | Arzneimittel mit verbesserter hydrophobie zur einarbeitung in medizinprodukt |
US8173167B2 (en) | 2005-04-12 | 2012-05-08 | Wisconsin Alumni Research Foundation | Micelle composition of polymer and passenger drug |
KR20100133475A (ko) * | 2008-04-10 | 2010-12-21 | 아브락시스 바이오사이언스, 엘엘씨 | 소수성 탁산 유도체의 조성물 그의 용도 |
CA2721153C (en) * | 2008-04-10 | 2018-10-02 | Abraxis Bioscience, Llc | Compositions of hydrophobic taxane derivatives and uses thereof |
KR101721281B1 (ko) | 2009-09-25 | 2017-04-10 | 위스콘신 얼럼나이 리서어치 화운데이션 | 치료제의 미셀 캡슐화 |
CN105503844A (zh) * | 2015-12-11 | 2016-04-20 | 上海大学 | C-13和c-7位结构改造的紫杉醇类化合物及其制备方法 |
CN111004195B (zh) * | 2019-12-03 | 2022-01-28 | 沈阳药科大学 | 卡巴他赛弱碱性衍生物及其制剂 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5059699A (en) * | 1990-08-28 | 1991-10-22 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
US5278324A (en) * | 1990-08-28 | 1994-01-11 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
KR100378612B1 (ko) * | 1992-12-23 | 2003-04-03 | 브리스톨-마이어스스퀴브컴파니 | 신규 측쇄-함유 탁산 및 그의 중간체 화합물 |
IL108316A (en) * | 1993-01-15 | 2006-10-31 | Univ Florida State | History of C-10 Texan and pharmaceuticals containing them |
US5580899A (en) * | 1995-01-09 | 1996-12-03 | The Liposome Company, Inc. | Hydrophobic taxane derivatives |
-
1996
- 1996-09-12 WO PCT/US1996/014631 patent/WO1997010234A1/en active IP Right Grant
- 1996-09-12 TR TR1998/00443T patent/TR199800443T1/xx unknown
- 1996-09-12 EP EP96930847A patent/EP0902783B1/de not_active Expired - Lifetime
- 1996-09-12 AT AT96930847T patent/ATE216377T1/de not_active IP Right Cessation
- 1996-09-12 ES ES02008590T patent/ES2252347T3/es not_active Expired - Lifetime
- 1996-09-12 DE DE69620802T patent/DE69620802T2/de not_active Expired - Fee Related
- 1996-09-12 MX MX9801871A patent/MX9801871A/es not_active IP Right Cessation
- 1996-09-12 CN CN96198237A patent/CN1100770C/zh not_active Expired - Fee Related
- 1996-09-12 CA CA002231750A patent/CA2231750C/en not_active Expired - Fee Related
- 1996-09-12 KR KR10-1998-0701653A patent/KR100401220B1/ko not_active IP Right Cessation
- 1996-09-12 ES ES96930847T patent/ES2179208T3/es not_active Expired - Lifetime
- 1996-09-12 CZ CZ1998711A patent/CZ288562B6/cs not_active IP Right Cessation
- 1996-09-12 PT PT96930847T patent/PT902783E/pt unknown
- 1996-09-12 DK DK02008590T patent/DK1229030T3/da active
- 1996-09-12 US US08/712,684 patent/US5703117A/en not_active Expired - Fee Related
- 1996-09-12 NZ NZ318300A patent/NZ318300A/xx unknown
- 1996-09-12 DK DK96930847T patent/DK0902783T3/da active
- 1996-09-12 AT AT02008590T patent/ATE309235T1/de not_active IP Right Cessation
- 1996-09-12 SK SK334-98A patent/SK283199B6/sk unknown
- 1996-09-12 PL PL96325477A patent/PL187738B1/pl not_active IP Right Cessation
- 1996-09-12 DE DE69635428T patent/DE69635428T2/de not_active Expired - Fee Related
- 1996-09-12 IL IL12359596A patent/IL123595A/xx not_active IP Right Cessation
- 1996-09-12 JP JP51210297A patent/JP4192208B2/ja not_active Expired - Fee Related
- 1996-09-12 HU HU9901433A patent/HU226325B1/hu unknown
-
1998
- 1998-03-11 NO NO19981071A patent/NO319521B1/no unknown
-
1999
- 1999-03-18 HK HK99101119A patent/HK1016169A1/xx not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1229030 Country of ref document: EP |
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EEFA | Change of the company name | ||
REN | Ceased due to non-payment of the annual fee |