PE20091352A1 - Composicion que comprende anticuerpo que se fija al dominio ii de her2, y sus variantes acidas - Google Patents
Composicion que comprende anticuerpo que se fija al dominio ii de her2, y sus variantes acidasInfo
- Publication number
- PE20091352A1 PE20091352A1 PE2009000115A PE2009000115A PE20091352A1 PE 20091352 A1 PE20091352 A1 PE 20091352A1 PE 2009000115 A PE2009000115 A PE 2009000115A PE 2009000115 A PE2009000115 A PE 2009000115A PE 20091352 A1 PE20091352 A1 PE 20091352A1
- Authority
- PE
- Peru
- Prior art keywords
- her2
- variant
- domain
- fixed
- acid variants
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
- C07K2317/41—Glycosylation, sialylation, or fucosylation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
Abstract
SE REFIERE A UNA COMPOSICION FARMACEUTICA QUE CONTIENE UN ANTICUERPO DE HER2 DE ESPECIE PRINCIPAL QUE SE FIJA AL DOMINIO II DE HER2 Y SUS VARIANTES ACIDAS TALES COMO LA VARIANTE GLICADA, VARIANTE REDUCIDA DE DISULFUROS, VARIANTE NO REDUCTIBLE, ENTRE OTROS, DONDE DICHO ANTICUERPO HER2 COMPRENDE LA SECUENCIA DE AMINOACIDOS VARIABLE LIVIANA EN LA SEC ID NO:3 Y LA SECUENCIA DE AMINOACIDOS VARIABLE PESADA EN LA SEC ID NO:4. SE REFIERE TAMBIEN A UN PROCEDIMIENTO DE PREPARACION DE DICHA COMPOSICION QUE ES UTIL EN EL TRATAMIENTO DE CANCER, PSORIASIS, ENDOMETRIOSIS, OSTEOPOROSIS
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2482508P | 2008-01-30 | 2008-01-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20091352A1 true PE20091352A1 (es) | 2009-09-16 |
Family
ID=40672664
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2013002537A PE20140579A1 (es) | 2008-01-30 | 2009-01-28 | Composicion que comprende anticuerpo que se fija al dominio ii de her2, y sus variantes acidas |
PE2019000440A PE20190906A1 (es) | 2008-01-30 | 2009-01-28 | Composicion que comprende anticuerpo que se fija al dominio ii de her2, y sus variantes acidas |
PE2009000115A PE20091352A1 (es) | 2008-01-30 | 2009-01-28 | Composicion que comprende anticuerpo que se fija al dominio ii de her2, y sus variantes acidas |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2013002537A PE20140579A1 (es) | 2008-01-30 | 2009-01-28 | Composicion que comprende anticuerpo que se fija al dominio ii de her2, y sus variantes acidas |
PE2019000440A PE20190906A1 (es) | 2008-01-30 | 2009-01-28 | Composicion que comprende anticuerpo que se fija al dominio ii de her2, y sus variantes acidas |
Country Status (37)
Country | Link |
---|---|
US (7) | US8652474B2 (es) |
EP (3) | EP2238172B1 (es) |
JP (2) | JP5933179B2 (es) |
KR (1) | KR101223941B1 (es) |
CN (1) | CN101981056B (es) |
AR (2) | AR070276A1 (es) |
AU (1) | AU2009210545C1 (es) |
BR (1) | BRPI0905733B8 (es) |
CA (1) | CA2711798C (es) |
CL (1) | CL2009000178A1 (es) |
CO (1) | CO6231039A2 (es) |
CR (2) | CR11648A (es) |
CY (2) | CY1120191T1 (es) |
DK (2) | DK3401335T3 (es) |
EC (1) | ECSP10010433A (es) |
ES (2) | ES2882041T3 (es) |
HK (1) | HK1151543A1 (es) |
HR (2) | HRP20211469T1 (es) |
HU (2) | HUE055108T2 (es) |
IL (2) | IL206931A (es) |
LT (2) | LT3401335T (es) |
MA (1) | MA32099B1 (es) |
MX (1) | MX2010008035A (es) |
MY (1) | MY158560A (es) |
NO (1) | NO2238172T3 (es) |
NZ (1) | NZ586754A (es) |
PE (3) | PE20140579A1 (es) |
PL (2) | PL2238172T3 (es) |
PT (2) | PT3401335T (es) |
RS (2) | RS57109B1 (es) |
RU (3) | RU2543664C2 (es) |
SG (1) | SG190607A1 (es) |
SI (2) | SI3401335T1 (es) |
TW (1) | TWI472339B (es) |
UA (1) | UA104585C2 (es) |
WO (1) | WO2009099829A1 (es) |
ZA (1) | ZA201004898B (es) |
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