PA8491501A1 - Acidos oxamicos y derivados como ligandos de receptores tiroideos - Google Patents

Acidos oxamicos y derivados como ligandos de receptores tiroideos

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Publication number
PA8491501A1
PA8491501A1 PA20008491501A PA8491501A PA8491501A1 PA 8491501 A1 PA8491501 A1 PA 8491501A1 PA 20008491501 A PA20008491501 A PA 20008491501A PA 8491501 A PA8491501 A PA 8491501A PA 8491501 A1 PA8491501 A1 PA 8491501A1
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Panama
Prior art keywords
isomers
compounds
ligands
derivatives
gorgeous
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PA20008491501A
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English (en)
Inventor
Yuan-Ching Phoebe Chiang
Robert Lee Dow
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Pfizer Prod Inc
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Publication of PA8491501A1 publication Critical patent/PA8491501A1/es

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    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
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  • Indole Compounds (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA NUEVOS COMPUESTOS DE LA FORMULA 1 Y PROFARMACOS DE LOS MISMOS, ISOMEROS GEOMETRICOS Y OPTICOS DE LOS MISMOS Y SALES FARMACEUTICAMENTE ACEPTABLES DE TALES COMPUESTOS, PROFARMACOS E ISOMEROS, EN LOS QUE R1 -R8 Y W SON COMO SE DESCRIBEN EN ESTE DOCUMENTO. TAMBIEN SE PROPORCIONAN COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS, PROFARMACOS, ISOMEROS O SALES FARMACEUTICAMENTE ACEPTABLES DE LOS MISMOS, Y PROCEDIMIENTOS, COMPOSICIONES FARMACEUTICAS Y ESTUCHES PARA EL TRATAMIENTO DE LA OBESIDAD, HIPERLIPIDEMIA, GLAUCOMA, ARRITMIA CARDIACA, TRASTORNOS CUTANEOS, ENFERMEDAD DEL TIROIDES, HIPOTIROIDISMO Y TRASTORNOS Y ENFERMEDADES RELACIONADAS TALES COMO DIABETES MELLITUS, ATEROSCLEROSIS, HIPERTENSION, ENFERMEDAD CARDIACA CORONARIA, HIPERCOLESTEROLEMIA, DEPRESION Y OSTEOPOROSIS.
PA20008491501A 1999-03-01 2000-02-29 Acidos oxamicos y derivados como ligandos de receptores tiroideos PA8491501A1 (es)

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