NO942977L - Piperazin og piperidinderivater og anvendelse derav som antipsykotiske midler - Google Patents

Piperazin og piperidinderivater og anvendelse derav som antipsykotiske midler

Info

Publication number
NO942977L
NO942977L NO942977A NO942977A NO942977L NO 942977 L NO942977 L NO 942977L NO 942977 A NO942977 A NO 942977A NO 942977 A NO942977 A NO 942977A NO 942977 L NO942977 L NO 942977L
Authority
NO
Norway
Prior art keywords
piperazine
piperidine derivatives
antipsychotic agents
group
therapy
Prior art date
Application number
NO942977A
Other languages
English (en)
Other versions
NO942977D0 (no
Inventor
Henry Mark Norman
Frank Navas
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of NO942977D0 publication Critical patent/NO942977D0/no
Publication of NO942977L publication Critical patent/NO942977L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

En gruppe plperazln og piperldinderivater, fremgangs- måte for fremstilling derav, farmasøytiske sammen- setninger Inneholdende disse og anvendelse l terapi, spesielt for behandling psykotiske forstyrrelser, er beskrevet. hvor Y betyr en gruppe med formel (a), (b) eller (c): (a) hvor en enkeltllnje ledsaget av en stiplet linje (---) betyr en enkeltblndlng eller en dobbeltblnding.
NO942977A 1992-02-12 1994-08-11 Piperazin og piperidinderivater og anvendelse derav som antipsykotiske midler NO942977L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929202915A GB9202915D0 (en) 1992-02-12 1992-02-12 Chemical compounds
PCT/GB1993/000285 WO1993016073A1 (en) 1992-02-12 1993-02-11 Piperazine and piperidine derivatives, and their use as antipsychotics

Publications (2)

Publication Number Publication Date
NO942977D0 NO942977D0 (no) 1994-08-11
NO942977L true NO942977L (no) 1994-10-10

Family

ID=10710223

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942977A NO942977L (no) 1992-02-12 1994-08-11 Piperazin og piperidinderivater og anvendelse derav som antipsykotiske midler

Country Status (16)

Country Link
EP (1) EP0625978A1 (no)
JP (1) JPH07503723A (no)
KR (1) KR950700290A (no)
AU (1) AU3460393A (no)
CA (1) CA2117434A1 (no)
CZ (1) CZ194994A3 (no)
FI (1) FI943718A0 (no)
GB (1) GB9202915D0 (no)
HU (1) HUT72309A (no)
IL (1) IL104690A0 (no)
MX (1) MX9300786A (no)
NO (1) NO942977L (no)
RU (1) RU94038064A (no)
SK (1) SK96494A3 (no)
WO (1) WO1993016073A1 (no)
ZA (1) ZA93958B (no)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364866A (en) * 1989-05-19 1994-11-15 Hoechst-Roussel Pharmaceuticals, Inc. Heteroarylpiperidines, pyrrolidines and piperazines and their use as antipsychotics and analetics
US5776963A (en) 1989-05-19 1998-07-07 Hoechst Marion Roussel, Inc. 3-(heteroaryl)-1- (2,3-dihydro-1h-isoindol-2-yl)alkyl!pyrrolidines and 3-(heteroaryl)-1- (2,3-dihydro-1h-indol-1-yl)alkyl!pyrrolidines and related compounds and their therapeutic untility
RU2118322C1 (ru) * 1993-07-05 1998-08-27 Дюфар Интернэшнл Рисерч Б.В. 2,3-дигидро-1,4-бензодиокси-5-ил-пиперазиновые производные или их соли
US5874429A (en) * 1993-12-24 1999-02-23 Suntory Limited Benzothiazine derivative
US6001827A (en) * 1993-12-24 1999-12-14 Suntory Limited Benzothiazine derivative
JPH0912562A (ja) * 1995-06-22 1997-01-14 Suntory Ltd 置換ベンゾチアジン誘導体
WO1995018117A1 (fr) * 1993-12-24 1995-07-06 Suntory Limited Derive de benzothiazine
WO1996014297A1 (fr) * 1994-11-04 1996-05-17 Sumitomo Pharmaceuticals Company, Limited Nouveaux derives de lactame
PT732332E (pt) * 1995-03-17 2002-06-28 Aventis Pharma Inc Benzotienilpiperazinas substituidas sua utilizacao como medicamentos e processos para a sua preparacao
US6087364A (en) * 1998-01-29 2000-07-11 Warner-Lambert Company Dopamine D4 receptor antagonists
DE19814084B4 (de) 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
US7030142B1 (en) 1999-04-06 2006-04-18 Sepracor Inc. Methods for the treatment of neuroleptic and related disorders using ziprasidone metabolites
AU4062900A (en) * 1999-04-06 2000-10-23 Sepracor, Inc. Methods and compositions for the treatment of neuroleptic and related disorders using ziprasidone metabolites
AR028685A1 (es) 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol
DE10234673B4 (de) 2002-07-30 2007-08-16 Schwarz Pharma Ag Heißschmelz-TTS zur Verabreichung von Rotigotin und Verfahren zu seiner Herstellung sowie Verwendung von Rotigotin bei der Herstellung eines TTS im Heißschmelzverfahren
US8246979B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system for the administration of rotigotine
US8246980B2 (en) 2002-07-30 2012-08-21 Ucb Pharma Gmbh Transdermal delivery system
JP4745661B2 (ja) 2002-08-22 2011-08-10 大日本住友製薬株式会社 統合失調症治療剤
DE10261696A1 (de) 2002-12-30 2004-07-15 Schwarz Pharma Ag Vorrichtung zur transdermalen Verabreichung von Rotigotin-Base
CN1826338B (zh) 2003-06-23 2011-07-13 大日本住友制药株式会社 老年性痴呆症治疗药
DE10334188B4 (de) 2003-07-26 2007-07-05 Schwarz Pharma Ag Verwendung von Rotigotin zur Behandlung von Depressionen
US20070160537A1 (en) 2004-02-20 2007-07-12 Takeo Ishiyama In vivo screening method of therapeutic agent for memory/learning dysfunctions by schizophrenia
JP2010514837A (ja) * 2007-01-03 2010-05-06 コーテックス ファーマシューティカルズ， インコーポレイテッド グルタミン酸作動性シナプス反応を強化するための３−置換−［１，２，３］ベンゾトリアジノン化合物
US8258139B2 (en) 2010-11-08 2012-09-04 Dainippon Sumitomo Pharma Co., Ltd. Method of treatment for mental disorders
GB201102248D0 (en) 2011-02-09 2011-03-23 Isis Innovation Treatment of bipolar disorder
US8981095B2 (en) 2011-07-28 2015-03-17 Mapi Pharma Ltd. Intermediate compounds and process for the preparation of lurasidone and salts thereof
PT3027598T (pt) * 2013-07-31 2017-07-17 Merck Patent Gmbh Derivados de oxoquinazolinil-butanamida
CN105669665A (zh) * 2016-03-15 2016-06-15 烟台贝森医药科技有限公司 哌罗匹隆的制备方法
WO2018035046A1 (en) 2016-08-15 2018-02-22 President And Fellows Of Harvard College Treating infections using idsd from proteus mirabilis
CN115124464B (zh) * 2022-07-04 2023-06-06 新乡学院 一种喹啉二酮磺酰哌嗪杂合体及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2258843B1 (no) * 1974-01-30 1977-09-09 Roussel Uclaf
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
JPH0625181B2 (ja) * 1985-03-27 1994-04-06 住友製薬株式会社 新規なイミド誘導体
AU593194B2 (en) * 1986-09-26 1990-02-01 Sumitomo Pharmaceuticals Company, Limited Imide derivatives ,and their production and use
CA1335289C (en) * 1987-10-26 1995-04-18 Fujio Antoku Piperidinyl benzisoxazole derivatives, their production and pharmaceutical use
US5001130A (en) * 1988-02-18 1991-03-19 Bristol-Myers Company Psychotropic heterobicycloalkylpiperazine derivatives
US4780466A (en) * 1988-03-17 1988-10-25 Hoechst-Roussel Pharmaceuticals, Inc. Arylpiperazinylalkoxy derivatives of cyclic imides
NZ230045A (en) * 1988-08-05 1990-11-27 Janssen Pharmaceutica Nv 3-piperazinylbenzazole derivatives and pharmaceutical compositions
US4968792A (en) * 1989-09-25 1990-11-06 American Home Products Corporation Psychotropic benzisothiazole derivatives
JP2800953B2 (ja) * 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体

Also Published As

Publication number Publication date
FI943718A (fi) 1994-08-11
EP0625978A1 (en) 1994-11-30
JPH07503723A (ja) 1995-04-20
GB9202915D0 (en) 1992-03-25
SK96494A3 (en) 1995-07-11
HU9402343D0 (en) 1994-10-28
HUT72309A (en) 1996-04-29
AU3460393A (en) 1993-09-03
ZA93958B (en) 1994-08-11
RU94038064A (ru) 1997-05-27
KR950700290A (ko) 1995-01-16
CA2117434A1 (en) 1993-08-19
MX9300786A (es) 1994-03-31
FI943718A0 (fi) 1994-08-11
IL104690A0 (en) 1993-06-10
NO942977D0 (no) 1994-08-11
CZ194994A3 (en) 1995-09-13
WO1993016073A1 (en) 1993-08-19

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