NO2014005I1 - olodaterol, syreaddisjonssalter og farmakologisk akseptable syrer derav - Google Patents

olodaterol, syreaddisjonssalter og farmakologisk akseptable syrer derav

Info

Publication number
NO2014005I1
NO2014005I1 NO2014005C NO2014005C NO2014005I1 NO 2014005 I1 NO2014005 I1 NO 2014005I1 NO 2014005 C NO2014005 C NO 2014005C NO 2014005 C NO2014005 C NO 2014005C NO 2014005 I1 NO2014005 I1 NO 2014005I1
Authority
NO
Norway
Prior art keywords
olodaterol
acid addition
addition salts
pharmacologically acceptable
acceptable acids
Prior art date
Application number
NO2014005C
Other languages
English (en)
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32185709&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO2014005(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO2014005I1 publication Critical patent/NO2014005I1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/34—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings
    • C07D265/36—1,4-Oxazines; Hydrogenated 1,4-oxazines condensed with carbocyclic rings condensed with one six-membered ring
NO2014005C 2002-11-15 2014-03-10 olodaterol, syreaddisjonssalter og farmakologisk akseptable syrer derav NO2014005I1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10253282A DE10253282A1 (de) 2002-11-15 2002-11-15 Neue Arzneimittel zur Behandlung von chronisch obstruktiver Lungenerkrankung
PCT/EP2003/012565 WO2004045618A2 (de) 2002-11-15 2003-11-11 Neue arzneimittel zur behandlung von chronisch obstruktiver lungenerkrankung

Publications (1)

Publication Number Publication Date
NO2014005I1 true NO2014005I1 (no) 2014-03-10

Family

ID=32185709

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20052883A NO334314B1 (no) 2002-11-15 2005-06-14 Forbindelser, farmasøytiske formuleringer inneholdende slike samt anvendelse av disse for fremstilling av medikamenter for behandling av kronisk obstruktiv lungesykdom
NO2014005C NO2014005I1 (no) 2002-11-15 2014-03-10 olodaterol, syreaddisjonssalter og farmakologisk akseptable syrer derav

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20052883A NO334314B1 (no) 2002-11-15 2005-06-14 Forbindelser, farmasøytiske formuleringer inneholdende slike samt anvendelse av disse for fremstilling av medikamenter for behandling av kronisk obstruktiv lungesykdom

Country Status (38)

Country Link
EP (2) EP1562603B3 (no)
JP (1) JP4317138B2 (no)
KR (1) KR101092247B1 (no)
CN (3) CN101735166A (no)
AR (2) AR041969A1 (no)
AT (1) ATE430569T1 (no)
AU (1) AU2003285326B2 (no)
BE (1) BE2014C016I2 (no)
BR (1) BRPI0316264B8 (no)
CA (1) CA2506082C (no)
CO (1) CO5570670A2 (no)
CY (2) CY1110500T1 (no)
DE (2) DE10253282A1 (no)
DK (1) DK1562603T3 (no)
EA (1) EA008665B1 (no)
EC (1) ECSP055774A (no)
ES (1) ES2326878T7 (no)
FR (1) FR14C0049I2 (no)
HR (1) HRP20050432B1 (no)
HU (1) HUS1400011I1 (no)
IL (1) IL167900A (no)
LT (1) LTC1562603I2 (no)
LU (1) LU92433I2 (no)
ME (1) ME00354B (no)
MX (1) MXPA05005081A (no)
MY (1) MY136034A (no)
NL (1) NL300650I2 (no)
NO (2) NO334314B1 (no)
NZ (1) NZ540661A (no)
PE (1) PE20040694A1 (no)
PL (1) PL212238B1 (no)
PT (1) PT1562603E (no)
RS (1) RS51607B (no)
SI (1) SI1562603T1 (no)
TW (1) TWI343812B (no)
UA (1) UA81276C2 (no)
WO (1) WO2004045618A2 (no)
ZA (1) ZA200502246B (no)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
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US20050256115A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Aerosol formulation for the inhalation of beta-agonists
DE102004024452A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Aerosolformulierung für die Inhalation von Betaagonisten
DE102004024454A1 (de) * 2004-05-14 2005-12-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Enantiomerenreine Betaagonisten, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel
DE102004024451A1 (de) * 2004-05-14 2005-12-22 Boehringer Ingelheim Pharma Gmbh & Co. Kg Pulverformulierungen für die Inhalation, die Enantiomerenreine Betaagonisten enthalten
US7220742B2 (en) 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
US7745621B2 (en) 2004-05-14 2010-06-29 Boehringer Ingelheim International Gmbh Long acting bronchodilators for the treatment of respiratory diseases
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GB0411056D0 (en) 2004-05-18 2004-06-23 Novartis Ag Organic compounds
DE102004045648A1 (de) * 2004-09-21 2006-03-23 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Betamimetika zur Behandlung von Atemwegserkrankungen
GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0424284D0 (en) 2004-11-02 2004-12-01 Novartis Ag Organic compounds
GB0426164D0 (en) 2004-11-29 2004-12-29 Novartis Ag Organic compounds
DE102005007654A1 (de) 2005-02-19 2006-08-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue langwirksame Betamimetika zur Behandlung von Atemwegserkrankungen
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
GB0510390D0 (en) 2005-05-20 2005-06-29 Novartis Ag Organic compounds
DE102005030733A1 (de) * 2005-07-01 2007-01-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Arzneimittelkombinationen zur Behandlung von Atemwegserkrankungen enthaltend langwirksame Beta-2-Agonisten und wenigstens einen weiteren Wirkstoff
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NZ566068A (en) 2005-08-08 2011-03-31 Argenta Discovery Ltd Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses
JP5270343B2 (ja) 2005-08-15 2013-08-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベータミメティックスの製造方法
US20070088030A1 (en) 2005-10-10 2007-04-19 Barbara Niklaus-Humke Aerosol formulations for the inhalation of beta-agonists
TWI396541B (zh) 2005-10-10 2013-05-21 Boehringer Ingelheim Int 用於治療呼吸疾病之新穎藥物組合
EP2532678A1 (en) 2005-10-21 2012-12-12 Novartis AG Human antibodies against il13 and therapeutic uses
BRPI0618370A2 (pt) * 2005-11-09 2011-08-30 Boehringer Ingelheim Int formulação aerossol de medicamento, uso do mesmo e kit de inalação
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
WO2007093608A1 (de) * 2006-02-16 2007-08-23 Boehringer Ingelheim International Gmbh Arzneimittelkombinationen zur behandlung von atemwegserkrankungen
PE20080142A1 (es) * 2006-03-15 2008-04-14 Boehringer Ingelheim Int Beta-agonistas enantiomericamente puros y sus procedimientos de preparacion
PT2013211E (pt) 2006-04-21 2012-06-21 Novartis Ag Derivados de purina para utilização como agonistas de receptores a2a de adenosina
WO2008017638A1 (de) * 2006-08-07 2008-02-14 Boehringer Ingelheim International Gmbh Enantiomerenreine betaagonisten, verfahren zu deren herstellung und deren verwendung als arzneimittel
UY30542A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de agonistas beta
UY30543A1 (es) * 2006-08-18 2008-03-31 Boehringer Ingelheim Int Formulacion de aerosol para la inhalacion de beta- agonistas
ATE502943T1 (de) 2006-09-29 2011-04-15 Novartis Ag Pyrazolopyrimidine als pi3k-lipidkinasehemmer
CN101522682A (zh) 2006-10-30 2009-09-02 诺瓦提斯公司 作为抗炎剂的杂环化合物
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US20100022770A1 (en) * 2007-01-25 2010-01-28 Boehringer Ingelheim International Gmbh Process for the manufacturing of beta mimetics
PL2155721T3 (pl) 2007-05-07 2011-07-29 Novartis Ag Związki organiczne
CL2008003651A1 (es) 2007-12-10 2009-06-19 Novartis Ag Compuestos derivados de 3,5-diamino-6-cloropirazinamida sustituida; composicion farmaceutica; combinacion farmaceutica; y uso en el tratamiento de una condición inflamatoria o alergica, en particular una enfermedad inflamatoria u obstructiva de las vias respiratorias.
PL2231642T3 (pl) 2008-01-11 2014-04-30 Novartis Ag Pirymidyny jako inhibitory kinazy
BRPI0915018A2 (pt) 2008-06-10 2015-10-27 Novartis Ag compostos orgânicos
US8236786B2 (en) 2008-08-07 2012-08-07 Pulmagen Therapeutics (Inflammation) Limited Respiratory disease treatment
US8362064B2 (en) 2008-12-30 2013-01-29 Pulmagen Theraputics (Inflammation) Limited Sulfonamide compounds for the treatment of respiratory disorders
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WO2010150014A1 (en) 2009-06-24 2010-12-29 Pulmagen Therapeutics (Inflammation) Limited 5r- 5 -deuterated glitazones for respiratory disease treatment
US8389526B2 (en) 2009-08-07 2013-03-05 Novartis Ag 3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
EA201200260A1 (ru) 2009-08-12 2012-09-28 Новартис Аг Гетероциклические гидразоны и их применение для лечения рака и воспаления
MX2012002066A (es) 2009-08-17 2012-03-29 Intellikine Inc Compuestos heterociclicos y usos de los mismos.
AU2010310449A1 (en) 2009-10-22 2012-05-03 Vertex Pharmaceuticals Incorporated Compositions for treatment of cystic fibrosis and other chronic diseases
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GB0918923D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminothiazole derivatives
GB0918922D0 (en) 2009-10-28 2009-12-16 Vantia Ltd Aminopyridine derivatives
WO2011098746A1 (en) 2010-02-09 2011-08-18 Pulmagen Therapeutics (Inflammation) Limited Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone
GB201002224D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
GB201002243D0 (en) 2010-02-10 2010-03-31 Argenta Therapeutics Ltd Respiratory disease treatment
US8247436B2 (en) 2010-03-19 2012-08-21 Novartis Ag Pyridine and pyrazine derivative for the treatment of CF
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
US8372845B2 (en) 2010-09-17 2013-02-12 Novartis Ag Pyrazine derivatives as enac blockers
EA024925B1 (ru) * 2010-09-21 2016-11-30 Интекрин Терапьютикс, Инк. Антидиабетические твердые фармацевтические композиции
WO2012107500A1 (en) 2011-02-10 2012-08-16 Novartis Ag [1, 2, 4] triazolo [4, 3 -b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
US9127000B2 (en) 2011-02-23 2015-09-08 Intellikine, LLC. Heterocyclic compounds and uses thereof
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MX339302B (es) 2011-09-15 2016-05-19 Novartis Ag 3-(quinolin-6-il-tio)-[1,2,4]-triazolo-[4,3-a]-piridinas 6-sustituidas como cinasas de tirosina.
WO2013038381A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine/pyrazine amide derivatives
WO2013038378A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
WO2013038386A1 (en) 2011-09-16 2013-03-21 Novartis Ag Heterocyclic compounds for the treatment of cystic fibrosis
WO2013038373A1 (en) 2011-09-16 2013-03-21 Novartis Ag Pyridine amide derivatives
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WO2013078440A2 (en) 2011-11-23 2013-05-30 Intellikine, Llc Enhanced treatment regimens using mtor inhibitors
US8809340B2 (en) 2012-03-19 2014-08-19 Novartis Ag Crystalline form
WO2013149581A1 (en) 2012-04-03 2013-10-10 Novartis Ag Combination products with tyrosine kinase inhibitors and their use
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US9073921B2 (en) 2013-03-01 2015-07-07 Novartis Ag Salt forms of bicyclic heterocyclic derivatives
WO2014151147A1 (en) 2013-03-15 2014-09-25 Intellikine, Llc Combination of kinase inhibitors and uses thereof
WO2015084804A1 (en) 2013-12-03 2015-06-11 Novartis Ag Combination of mdm2 inhibitor and braf inhibitor and their use
CA2945257A1 (en) 2014-04-24 2015-10-29 Novartis Ag Pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors
BR112016024484A2 (pt) 2014-04-24 2017-08-15 Novartis Ag derivados de aminopiridina como inibidores de fosfatidilinositol 3-quinase
EA032075B1 (ru) 2014-04-24 2019-04-30 Новартис Аг Производные аминопиразина в качестве ингибиторов фосфатидилинозитол-3-киназы
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CN108997248B (zh) * 2018-08-06 2023-08-01 上海方予健康医药科技有限公司 盐酸奥达特罗晶型b及其制备方法
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US4460581A (en) 1982-10-12 1984-07-17 Boehringer Ingelheim Kg (1-Hydroxy-2-amino-alkyl)-substituted benzoxazinones and benzoxazolinones
DE3743265A1 (de) * 1987-12-19 1989-06-29 Boehringer Ingelheim Kg Neue ammoniumverbindungen, ihre herstellung und verwendung
BR0110331A (pt) * 2000-04-27 2003-01-07 Boehringer Ingelheim Pharma Substâncias que mimetizam beta que têm uma atividade de longa duração, processos para prepará-las e o uso das mesmas como medicamentos

Also Published As

Publication number Publication date
LU92433I2 (fr) 2014-06-24
NL300650I2 (nl) 2017-11-02
IL167900A (en) 2013-06-27
WO2004045618A3 (de) 2004-09-30
CN1713914A (zh) 2005-12-28
KR101092247B1 (ko) 2011-12-12
FR14C0049I2 (fr) 2015-07-24
RS20050361A (en) 2007-04-10
EP1562603A2 (de) 2005-08-17
ES2326878T3 (es) 2009-10-21
NO334314B1 (no) 2014-02-03
PE20040694A1 (es) 2004-11-23
ZA200502246B (en) 2006-01-25
JP4317138B2 (ja) 2009-08-19
PT1562603E (pt) 2009-06-18
CN101735166A (zh) 2010-06-16
HUS1400011I1 (hu) 2022-02-28
TWI343812B (en) 2011-06-21
DE50311502D1 (de) 2009-06-18
PL375270A1 (en) 2005-11-28
CN101817800A (zh) 2010-09-01
CY1110500T1 (el) 2015-04-29
BRPI0316264B8 (pt) 2021-05-25
ME00354B (me) 2011-10-10
BR0316264A (pt) 2005-10-11
AR087241A2 (es) 2014-03-12
NZ540661A (en) 2007-12-21
EP2025338A1 (de) 2009-02-18
RS51607B (sr) 2011-08-31
EP1562603B3 (de) 2014-01-08
CA2506082A1 (en) 2004-06-03
BE2014C016I2 (no) 2023-03-07
CY2014032I2 (el) 2015-12-09
UA81276C2 (en) 2007-12-25
JP2006508140A (ja) 2006-03-09
ATE430569T1 (de) 2009-05-15
AU2003285326B2 (en) 2009-06-04
PL212238B1 (pl) 2012-08-31
MXPA05005081A (es) 2005-07-01
DE10253282A1 (de) 2004-05-27
KR20050075013A (ko) 2005-07-19
AU2003285326A1 (en) 2004-06-15
AR041969A1 (es) 2005-06-01
MEP53608A (en) 2011-05-10
DK1562603T3 (da) 2009-09-07
CA2506082C (en) 2011-06-21
ECSP055774A (es) 2005-11-22
EA008665B1 (ru) 2007-06-29
ES2326878T7 (es) 2014-03-11
NO20052883L (no) 2005-06-14
CY2014032I1 (el) 2015-12-09
TW200423943A (en) 2004-11-16
MY136034A (en) 2008-07-31
LTC1562603I2 (lt) 2016-12-12
HRP20050432A2 (en) 2006-06-30
SI1562603T1 (sl) 2009-10-31
WO2004045618A2 (de) 2004-06-03
FR14C0049I1 (no) 2014-08-08
EP1562603B1 (de) 2009-05-06
EA200500715A1 (ru) 2005-12-29
CO5570670A2 (es) 2005-10-31
BRPI0316264B1 (pt) 2019-04-09
HRP20050432B1 (en) 2012-01-31

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