MXPA05010958A - Derivados indazol como inhibidores jnk. - Google Patents

Derivados indazol como inhibidores jnk.

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Publication number
MXPA05010958A
MXPA05010958A MXPA05010958A MXPA05010958A MXPA05010958A MX PA05010958 A MXPA05010958 A MX PA05010958A MX PA05010958 A MXPA05010958 A MX PA05010958A MX PA05010958 A MXPA05010958 A MX PA05010958A MX PA05010958 A MXPA05010958 A MX PA05010958A
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MX
Mexico
Prior art keywords
indazole derivatives
compounds
jnk inhibitors
disorders
diseases
Prior art date
Application number
MXPA05010958A
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English (en)
Inventor
Rachel Ferri
Original Assignee
Signal Pharm Llc
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Publication date
Application filed by Signal Pharm Llc filed Critical Signal Pharm Llc
Publication of MXPA05010958A publication Critical patent/MXPA05010958A/es

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    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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Abstract

Esta invencion se dirige generalmente a Derivados Indazol que tienen la siguiente estructura (I) o una sal farmaceuticamente aceptable de los mismos, en donde R1, R2 y A son como se definen en la presente. Tales compuestos tienen utilidad en el tratamiento de un amplio rango de enfermedades y trastornos que son sensibles a la inhibicion JNK, tal como una enfermedad o trastorno inflamatorios. De este modo, los metodos para tratar tales enfermedades y trastornos tambien se describen, como son las composiciones farmaceuticas que contienen uno o mas compuestos de los compuestos anteriores.
MXPA05010958A 2003-04-16 2004-04-16 Derivados indazol como inhibidores jnk. MXPA05010958A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/414,839 US7211594B2 (en) 2000-07-31 2003-04-16 Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith
PCT/US2004/011958 WO2004094388A2 (en) 2003-04-16 2004-04-16 Indazole derivatives as jnk inhibitors

Publications (1)

Publication Number Publication Date
MXPA05010958A true MXPA05010958A (es) 2006-01-30

Family

ID=33309498

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA05010958A MXPA05010958A (es) 2003-04-16 2004-04-16 Derivados indazol como inhibidores jnk.

Country Status (9)

Country Link
US (1) US7211594B2 (es)
EP (1) EP1618093A2 (es)
JP (1) JP2006523721A (es)
AU (1) AU2004232981A1 (es)
BR (1) BRPI0409417A (es)
CA (1) CA2522682A1 (es)
MX (1) MXPA05010958A (es)
WO (1) WO2004094388A2 (es)
ZA (1) ZA200508359B (es)

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