EP0194599A3
(en)
|
1985-03-14 |
1988-01-20 |
Nissan Chemical Industries Ltd. |
Benzamide derivatives, process for producing the same, and soil fungicides containing the same
|
GB9122590D0
(en)
|
1991-10-24 |
1991-12-04 |
Lilly Industries Ltd |
Pharmaceutical compounds
|
DE4410453A1
(de)
|
1994-03-25 |
1995-09-28 |
Hoechst Ag |
Substituierte heterocyclische Carbonsäureamidester, ihre Herstellung und ihre Verwendung als Arzneimittel
|
GB9514160D0
(en)
|
1994-07-25 |
1995-09-13 |
Zeneca Ltd |
Aromatic compounds
|
CA2209902A1
(en)
|
1995-01-19 |
1996-07-25 |
Novartis Ag |
Herbicidal composition
|
EP0863708A1
(en)
|
1995-11-23 |
1998-09-16 |
Novartis AG |
Herbicidal composition
|
CA2238875C
(en)
|
1995-12-15 |
2003-09-16 |
Merck Frosst Canada Inc. |
Tri-aryl ethane derivatives as pde iv inhibitors
|
WO1998008818A1
(en)
|
1996-08-26 |
1998-03-05 |
Genetics Institute, Inc. |
Inhibitors of phospholipase enzymes
|
JPH10114654A
(ja)
|
1996-10-09 |
1998-05-06 |
Fujisawa Pharmaceut Co Ltd |
新規用途
|
WO1998031226A1
(de)
|
1997-01-15 |
1998-07-23 |
Novartis Ag |
Herbizides mittel
|
GB9716657D0
(en)
|
1997-08-07 |
1997-10-15 |
Zeneca Ltd |
Chemical compounds
|
DE19742951A1
(de)
|
1997-09-29 |
1999-04-15 |
Hoechst Schering Agrevo Gmbh |
Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
|
DE19802697A1
(de)
|
1998-01-24 |
1999-07-29 |
Bayer Ag |
Selektive Herbizide auf Basis von N-Aryl-triazolin(thi)onen und N-Arylsulfonylamino(thio)carbonyltriazolin(thi)onen
|
EP1069112A4
(en)
|
1998-02-13 |
2001-04-18 |
Kureha Chemical Ind Co Ltd |
N- (PHENYLSULFONYL) PICOLINAMIDE DERIVATIVES, METHOD FOR THEIR PREPARATION AND HERBICIDES
|
WO1999051574A1
(fr)
|
1998-04-06 |
1999-10-14 |
Fujisawa Pharmaceutical Co., Ltd. |
Derives d'indole
|
CZ20014366A3
(cs)
|
1999-06-10 |
2002-11-13 |
Warner-Lambert Company |
Způsob inhibice agregace amyloidních proteinů a zobrazení amyloidních usazenin za pouľití isoindolinových derivátů
|
DE19936438A1
(de)
|
1999-08-03 |
2001-02-08 |
Aventis Cropscience Gmbh |
Kombinationen von Herbiziden und Safenern
|
DE19940860A1
(de)
|
1999-08-27 |
2001-03-01 |
Bayer Ag |
Selektive Herbizide auf Basis eines substituierten Phenylsulfonyl aminocarbonyltriazolinons und Safenern II
|
DE19958381A1
(de)
|
1999-12-03 |
2001-06-07 |
Bayer Ag |
Herbizide auf Basis von N-Aryl-uracilen
|
AU2001286557A1
(en)
|
2000-08-23 |
2002-03-04 |
Merck Frosst Canada And Co. |
Method of treating or preventing urinary incontinence using prostanoid ep1 receptor antagonists
|
US6720338B2
(en)
|
2000-09-20 |
2004-04-13 |
Abbott Laboratories |
N-acylsulfonamide apoptosis promoters
|
US20020055631A1
(en)
|
2000-09-20 |
2002-05-09 |
Augeri David J. |
N-acylsulfonamide apoptosis promoters
|
UY26942A1
(es)
|
2000-09-20 |
2002-04-26 |
Abbott Lab |
N-acilsulfonamidas promotoras de la apoptosis
|
HUP0302477A2
(hu)
|
2000-10-10 |
2003-12-29 |
Smithkline Beecham Corp. |
Szubsztituált indolszármazékok, ezeket tartalmazó gyógyszerkészítmények és ezek alkalmazása PPAR-gamma kötő szerként
|
US20100074949A1
(en)
|
2008-08-13 |
2010-03-25 |
William Rowe |
Pharmaceutical composition and administration thereof
|
DE10119721A1
(de)
|
2001-04-21 |
2002-10-31 |
Bayer Cropscience Gmbh |
Herbizide Mittel enthaltend Benzoylcyclohexandione und Safener
|
EP1395566B1
(en)
|
2001-05-31 |
2007-09-12 |
Vicore Pharma AB |
Tricyclic compounds useful as angiotensin ii agonists
|
OA12626A
(en)
|
2001-06-28 |
2006-06-13 |
Pfizer Prod Inc |
triamide-substituted indoles, benzofuranes and benzothiophenes as inhibitors of microsomal triglyceride transfer protein (MTP)and/or apolipoprotein B(APO B) secretion.
|
DE10145019A1
(de)
|
2001-09-13 |
2003-04-03 |
Bayer Cropscience Gmbh |
Kombinationen aus Herbiziden und Safenern
|
DE10146873A1
(de)
|
2001-09-24 |
2003-04-17 |
Bayer Cropscience Gmbh |
Heterocyclische Amide und -Iminderivate, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel
|
MXPA04004657A
(es)
|
2001-11-14 |
2004-08-13 |
Teva Pharma |
Formas amorfas y cristalinas de potasio de losartan y proceso para su preparacion.
|
WO2003043655A1
(fr)
|
2001-11-19 |
2003-05-30 |
Ono Pharmaceutical Co., Ltd. |
Remedes pour la frequence urinaire
|
DE10157545A1
(de)
|
2001-11-23 |
2003-06-12 |
Bayer Cropscience Gmbh |
Herbizide Mittel enthaltend Benzoylpyrazole und Safener
|
EP1497270A4
(en)
|
2002-03-27 |
2006-01-04 |
Smithkline Beecham Corp |
AMID COMPOUNDS AND METHOD FOR THEIR USE
|
GB0212785D0
(en)
|
2002-05-31 |
2002-07-10 |
Glaxo Group Ltd |
Compounds
|
DE60304862T2
(de)
|
2002-06-08 |
2006-11-23 |
Bayer Cropscience Gmbh |
Kombinationen von herbiziden aromatischen carbonsäuren und safener-mitteln
|
DE10237461A1
(de)
|
2002-08-16 |
2004-02-26 |
Bayer Cropscience Gmbh |
Herbizide Mittel enthaltend Benzoylpyrazole und Safener
|
US20060019932A1
(en)
|
2002-09-06 |
2006-01-26 |
Mancini Joseph A |
Treatment of rheumatoid arthritis by inhibition of pde4
|
WO2004037798A1
(en)
|
2002-10-22 |
2004-05-06 |
Merck Frosst Canada & Co. |
Nitric oxide releasing selective cyclooxygenase-2 inhibitors
|
GB0225548D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Compounds
|
AU2003302106A1
(en)
|
2002-11-21 |
2004-06-15 |
Vicore Pharma Ab |
New tricyclic angiotensin ii agonists
|
WO2004056777A1
(en)
|
2002-12-20 |
2004-07-08 |
Pfizer Products Inc. |
Microsomal triglyceride transfer protein inhibitors
|
JP2006516028A
(ja)
|
2002-12-20 |
2006-06-15 |
ファイザー・プロダクツ・インク |
ミクロソームトリグリセリド輸送タンパク質阻害剤
|
EP1603884A4
(en)
|
2003-02-28 |
2008-05-28 |
Encysive Pharmaceuticals Inc |
PYRIDINE, PYRIMIDINE, QUINOLINE, QUINAZOLINE AND NAPHTHALENE UROTENSIN II RECEPTOR ANTAGONISTS
|
WO2004085420A1
(en)
|
2003-03-24 |
2004-10-07 |
Vicore Pharma Ab |
Bicyclic compounds useful as angiotensin ii agonists
|
WO2004111014A1
(en)
|
2003-06-06 |
2004-12-23 |
Vertex Pharmaceuticals Incorporated |
Pyrimidine derivatives as modulators of atp-binding cassette transporters
|
US7407976B2
(en)
|
2003-11-14 |
2008-08-05 |
Vertex Pharmaceuticals Incorporated |
Thiazoles and oxazoles useful as modulators of ATP-Binding Cassette transporters
|
GB0328024D0
(en)
|
2003-12-03 |
2004-01-07 |
Glaxo Group Ltd |
Compounds
|
CA2554716A1
(en)
|
2004-01-22 |
2005-08-04 |
Nitromed, Inc. |
Nitrosated and/or nitrosylated compounds, compositions and methods of use
|
AU2005210474B2
(en)
|
2004-01-30 |
2011-07-07 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding cassette transporters
|
US7977322B2
(en)
|
2004-08-20 |
2011-07-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
AP2006003685A0
(en)
|
2004-02-04 |
2006-08-31 |
Pfizer Prod Inc |
Substituted quinoline compounds
|
WO2005082414A2
(en)
|
2004-03-02 |
2005-09-09 |
Astellas Pharma Inc. |
Concomitant drugs of a sulfonamide and another therapeutic agent
|
CN102532048B
(zh)
|
2004-03-05 |
2015-06-24 |
日产化学工业株式会社 |
异噁唑啉取代苯甲酰胺化合物的制备中间体
|
WO2005099705A2
(en)
|
2004-03-24 |
2005-10-27 |
Bayer Pharmaceuticals Corporation |
Preparation of imidazole derivatives and methods of use
|
US7414037B2
(en)
|
2004-03-30 |
2008-08-19 |
The Regents Of The University Of California |
Hydrazide-containing CFTR inhibitor compounds and uses thereof
|
GB0410121D0
(en)
|
2004-05-06 |
2004-06-09 |
Glaxo Group Ltd |
Compounds
|
LT2489659T
(lt)
|
2004-06-24 |
2018-03-26 |
Vertex Pharmaceuticals Incorporated |
Atp rišančios kasetės transporterių moduliatoriai
|
US8354427B2
(en)
|
2004-06-24 |
2013-01-15 |
Vertex Pharmaceutical Incorporated |
Modulators of ATP-binding cassette transporters
|
US7550463B2
(en)
|
2004-09-15 |
2009-06-23 |
Shionogi & Co., Ltd. |
Carbamoylpyridone derivatives having inhibitory activity against HIV integrase
|
US7205296B2
(en)
|
2004-09-29 |
2007-04-17 |
Portola Pharmaceuticals, Inc. |
Substituted 2H-1,3-benzoxazin-4(3H)-ones
|
US20080287399A1
(en)
|
2004-12-14 |
2008-11-20 |
Astrazeneca Ab |
Substituted Aminopyridines and Uses Thereof
|
GB0428173D0
(en)
|
2004-12-23 |
2005-01-26 |
Astrazeneca Ab |
Compounds
|
US20100137378A1
(en)
|
2004-12-23 |
2010-06-03 |
Glaxo Group Limited |
Pyridine Compounds For The Treatment Of Prostaglandin Mediated Diseases
|
AU2006251624A1
(en)
|
2005-05-24 |
2006-11-30 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding cassette transporters
|
US20070032488A1
(en)
|
2005-08-05 |
2007-02-08 |
Genelabs Technologies, Inc. |
6-Membered aryl and heteroaryl derivatives for treating viruses
|
MX2008002019A
(es)
|
2005-08-11 |
2008-04-16 |
Vertex Pharma |
Moduladores del regulador de conductancia transmembrana de fibrosis quistica.
|
WO2007053641A2
(en)
|
2005-11-01 |
2007-05-10 |
Mars, Incorporated |
A-type procyanidins and inflammation
|
WO2007075946A1
(en)
|
2005-12-27 |
2007-07-05 |
Vertex Pharmaceuticals Incorporated |
Compounds useful in cftr assays and methods therewith
|
RS60205B1
(sr)
|
2005-12-28 |
2020-06-30 |
Vertex Pharma |
Farmaceutske kompozicije amorfnog oblika n-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksohinolin-3-karboksamida
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
CA2635760C
(en)
|
2005-12-28 |
2014-07-15 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters
|
JP2009532437A
(ja)
|
2006-04-05 |
2009-09-10 |
バイエル・クロツプサイエンス・エス・アー |
殺菌剤n−シクロプロピル−スルホニルアミド誘導体
|
MX2008012945A
(es)
|
2006-04-07 |
2009-01-15 |
Vertex Pharma |
Moduladores de transportadores de cartucho de union a adenosina-trifosfato celular (atp).
|
JP2009536969A
(ja)
|
2006-05-12 |
2009-10-22 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
N−[2,4−ビス(1,1−ジメチルエチル)−5−ヒドロキシフェニル]−1,4−ジヒドロ−4−オキソキノリン−3−カルボキサミド組成物
|
EP2038272B8
(en)
|
2006-06-30 |
2013-10-23 |
Sunesis Pharmaceuticals, Inc. |
Pyridinonyl pdk1 inhibitors
|
CA2668305C
(en)
|
2006-11-03 |
2017-01-03 |
Vertex Pharmaceuticals Incorporated |
Azaindole derivatives as cftr modulators
|
US7754739B2
(en)
|
2007-05-09 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of CFTR
|
WO2008100867A2
(en)
|
2007-02-12 |
2008-08-21 |
Intermune, Inc. |
Novel inhibitors hepatitis c virus replication
|
WO2008141385A1
(en)
|
2007-05-21 |
2008-11-27 |
Biota Scientific Management Pty Ltd |
Viral polymerase inhibitors
|
US8058299B2
(en)
|
2007-05-22 |
2011-11-15 |
Via Pharmaceuticals, Inc. |
Diacylglycerol acyltransferase inhibitors
|
US8173810B2
(en)
*
|
2007-05-25 |
2012-05-08 |
Amgen Inc. |
Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use
|
US8163909B2
(en)
*
|
2007-05-25 |
2012-04-24 |
Amgen Inc. |
Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use
|
GB0716532D0
(en)
|
2007-08-24 |
2007-10-03 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
US8143305B2
(en)
|
2007-08-29 |
2012-03-27 |
Schering Corporation |
2,3-substituted indole derivatives for treating viral infections
|
BRPI0816345A2
(pt)
|
2007-09-14 |
2015-02-24 |
Vertex Pharma |
Formas sólidas de n-[2,4-bis-(1,1-dimetiletil)-5-hidroxifenil]-1,4-diidro-4-o xoquinolin-3-carboxamida
|
AU2013231151B2
(en)
|
2007-11-16 |
2015-06-25 |
Vertex Pharmaceuticals Incorporated |
Isoquinoline modulators of ATP-Binding Cassette transporters
|
CN102099351A
(zh)
|
2007-11-16 |
2011-06-15 |
先灵公司 |
3-杂环取代的吲哚衍生物及其使用方法
|
GB0723794D0
(en)
|
2007-12-05 |
2008-01-16 |
Lectus Therapeutics Ltd |
Potassium ion channel modulators and uses thereof
|
PT2639222T
(pt)
|
2007-12-07 |
2016-11-01 |
Vertex Pharma |
Processo de produção de ácidos cicloalquilcarboxamido-piridina-benzoicos
|
CA2706920C
(en)
|
2007-12-07 |
2018-02-13 |
Vertex Pharmaceuticals Incorporated |
Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl)cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
AU2013270464B2
(en)
|
2008-03-31 |
2016-05-26 |
Vertex Pharmaceuticals Incorporated |
Pyridyl derivatives as CFTR modulators
|
WO2009127822A2
(en)
|
2008-04-16 |
2009-10-22 |
Biolipox Ab |
Bis-aryl compounds for use as medicaments
|
US20110112193A1
(en)
|
2008-05-14 |
2011-05-12 |
Peter Nilsson |
Bis-aryl compounds for use as medicaments
|
EP2145537A1
(en)
|
2008-07-09 |
2010-01-20 |
Bayer CropScience AG |
Plant growth regulator
|
UY31982A
(es)
|
2008-07-16 |
2010-02-26 |
Boehringer Ingelheim Int |
Derivados de 1,2-dihidropiridin-3-carboxamidas n-sustituidas
|
RS56894B1
(sr)
|
2008-08-13 |
2018-04-30 |
Vertex Pharma |
Farmaceutska kompozicija n-[2,4-bis(1,1-dimetiletil)-5-hidroksifenil]-1,4-dihidro-4-oksohinolin-3-karboksamida i njeno ordiniranje
|
US20110160227A1
(en)
|
2008-08-21 |
2011-06-30 |
Antony Shaw |
Prolyl Hydroxylase Inhibitors
|
BRPI0917719A2
(pt)
|
2008-08-27 |
2019-11-19 |
Calcimedica Inc |
compostos que modulam cálcio intracelular
|
UA104147C2
(uk)
|
2008-09-10 |
2014-01-10 |
Новартис Аг |
Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
|
PT2349263E
(pt)
|
2008-10-23 |
2014-07-28 |
Vertex Pharma |
Moduladores de regulador da condutância transmembranar da fibrose cística
|
UA104876C2
(uk)
|
2008-11-06 |
2014-03-25 |
Вертекс Фармасьютікалз Інкорпорейтед |
Модулятори atф-зв'язувальних касетних транспортерів
|
WO2010053471A1
(en)
|
2008-11-06 |
2010-05-14 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters
|
UA108193C2
(uk)
|
2008-12-04 |
2015-04-10 |
|
Апоптозіндукуючий засіб для лікування раку і імунних і аутоімунних захворювань
|
US20100160322A1
(en)
|
2008-12-04 |
2010-06-24 |
Abbott Laboratories |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
JP5699090B2
(ja)
|
2008-12-30 |
2015-04-08 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
嚢胞性線維症膜コンダクタンス調節因子のモジュレーター
|
KR20160066014A
(ko)
|
2009-01-19 |
2016-06-09 |
애브비 인코포레이티드 |
암, 면역 질환 및 자가면역 질환의 치료를 위한 아폽토시스-유도제
|
MX338802B
(es)
|
2009-03-11 |
2016-05-02 |
Bayer Cropscience Ag |
Cetoenoles sustituidos con haloalquilmetilenoxi-fenilo.
|
SI2408749T1
(sl)
|
2009-03-20 |
2018-10-30 |
Vertex Pharmaceuticals Incorporated |
Modulatorji regulatorja transmembranske prevodnosti pri cistični fibrozi
|
KR101955863B1
(ko)
|
2009-03-20 |
2019-03-07 |
버텍스 파마슈티칼스 인코포레이티드 |
낭성 섬유증 막횡단 전도도 조절자의 조정자의 제조 방법
|
JP5697163B2
(ja)
|
2009-03-26 |
2015-04-08 |
塩野義製薬株式会社 |
置換された3−ヒドロキシ−4−ピリドン誘導体
|
US20120129858A1
(en)
|
2009-04-20 |
2012-05-24 |
Institute For Oneworld Health |
Compounds, compositions and methods comprising pyridazine sulfonamide derivatives
|
SG175253A1
(en)
|
2009-05-26 |
2011-11-28 |
Abbott Lab |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
WO2011102514A1
(ja)
|
2010-02-22 |
2011-08-25 |
武田薬品工業株式会社 |
芳香環化合物
|
AU2011227021A1
(en)
|
2010-03-19 |
2012-10-18 |
Vertex Pharmaceuticals Incorporated |
Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
NZ700556A
(en)
|
2010-03-25 |
2016-04-29 |
Vertex Pharma |
Solid forms of (r)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide
|
HRP20211752T1
(hr)
|
2010-04-07 |
2022-02-18 |
Vertex Pharmaceuticals Incorporated |
Farmaceutski pripravci 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5-il)ciklopropankarboksamido)-3-metilpiridin-2-il)benzojeve kiseline i njihova primjena
|
TWI549950B
(zh)
|
2010-04-07 |
2016-09-21 |
維泰克斯製藥公司 |
3-(6-(1-(2,2-二氟苯并[d][1,3]二氧雜環戊烯-5-基)環丙烷甲醯胺基)-3-甲基吡啶-2-基)苯甲酸之固體形式
|
US8344137B2
(en)
|
2010-04-14 |
2013-01-01 |
Hoffman-La Roche Inc. |
3,3-dimethyl tetrahydroquinoline derivatives
|
SG10201505700QA
(en)
|
2010-04-22 |
2015-08-28 |
Vertex Pharma |
Process of producing cycloalkylcarboxamido-indole compounds
|
CA2796642A1
(en)
|
2010-04-22 |
2011-10-27 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions and administrations thereof
|
TWI520960B
(zh)
|
2010-05-26 |
2016-02-11 |
艾伯維有限公司 |
用於治療癌症及免疫及自體免疫疾病之細胞凋亡誘導劑
|
US8563593B2
(en)
|
2010-06-08 |
2013-10-22 |
Vertex Pharmaceuticals Incorporated |
Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
|
BR112013004443A8
(pt)
|
2010-08-23 |
2018-01-02 |
Vertex Pharma |
composições farmacêuticas de (r)-1-(2,2-difluorbenzo[d] [1,3]dioxol-5-il)-n-(1-(2,3-di-hidróxipropil)-6-flúor-2-(1-hidróxi-2-metilpropan-2-il)-1h-indol-5-il)ciclopropano carboxamida e administração das mesmas
|
WO2012027731A2
(en)
|
2010-08-27 |
2012-03-01 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical composition and administrations thereof
|
EP2630136A1
(en)
|
2010-10-21 |
2013-08-28 |
Universität des Saarlandes |
Selective cyp11b1 inhibitors for the treatment of cortisol dependent diseases
|
WO2012087938A1
(en)
|
2010-12-20 |
2012-06-28 |
Glaxosmithkline Llc |
Quinazolinone derivatives as antiviral agents
|
EP2471363A1
(de)
|
2010-12-30 |
2012-07-04 |
Bayer CropScience AG |
Verwendung von Aryl-, Heteroaryl- und Benzylsulfonamidocarbonsäuren, -carbonsäureestern, -carbonsäureamiden und -carbonitrilen oder deren Salze zur Steigerung der Stresstoleranz in Pflanzen
|
EP2669285A4
(en)
|
2011-01-26 |
2014-06-18 |
Kyorin Seiyaku Kk |
PYRAZOLOPYRIDINE DERIVATIVE OR PHARMACEUTICALLY UNINTENTIONAL SALT OF WHICH
|
US9000026B2
(en)
|
2011-02-17 |
2015-04-07 |
Bayer Intellectual Property Gmbh |
Substituted 3-(biphenyl-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4.5]dec-3-en-2-ones for therapy
|
US9204640B2
(en)
|
2011-03-01 |
2015-12-08 |
Bayer Intellectual Property Gmbh |
2-acyloxy-pyrrolin-4-ones
|
AR085585A1
(es)
|
2011-04-15 |
2013-10-09 |
Bayer Cropscience Ag |
Vinil- y alquinilciclohexanoles sustituidos como principios activos contra estres abiotico de plantas
|
WO2012166415A1
(en)
|
2011-05-27 |
2012-12-06 |
Amira Pharmaceuticals, Inc. |
Heterocyclic autotaxin inhibitors and uses thereof
|
IN2014DN00137A
(es)
|
2011-07-18 |
2015-05-22 |
Adolor Corp |
|
KR20140072037A
(ko)
|
2011-08-30 |
2014-06-12 |
씨에이치디아이 파운데이션, 인코포레이티드 |
키뉴레닌-3-모노옥시게나제 억제제, 약학적 조성물 및 이의 사용 방법
|
JP6138797B2
(ja)
|
2011-09-16 |
2017-05-31 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
植物収量を向上させるためのアシルスルホンアミド類の使用
|
WO2013038373A1
(en)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Pyridine amide derivatives
|
BR112014006940A2
(pt)
|
2011-09-23 |
2017-04-04 |
Bayer Ip Gmbh |
uso de derivados de ácido 1-fenilpirazol-3-carboxílico 4-substituído como agentes contra estresse abiótico em plantas
|
MX357328B
(es)
|
2011-11-08 |
2018-07-05 |
Vertex Pharma |
Moduladores de trasportadores de casete enlazante de atp.
|
US8426450B1
(en)
|
2011-11-29 |
2013-04-23 |
Helsinn Healthcare Sa |
Substituted 4-phenyl pyridines having anti-emetic effect
|
CA2862859C
(en)
|
2012-01-25 |
2022-08-02 |
Vertex Pharmaceuticals Incorporated |
Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
JP2015083542A
(ja)
|
2012-02-08 |
2015-04-30 |
大日本住友製薬株式会社 |
3位置換プロリン誘導体
|
NZ629199A
(en)
|
2012-02-27 |
2017-01-27 |
Vertex Pharma |
Pharmaceutical compositions comprising a solid dispersion of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
US8889730B2
(en)
|
2012-04-10 |
2014-11-18 |
Pfizer Inc. |
Indole and indazole compounds that activate AMPK
|
AU2012377446A1
(en)
|
2012-04-20 |
2014-10-23 |
Vertex Pharmaceuticals Incorporated |
Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
WO2013177224A1
(en)
|
2012-05-22 |
2013-11-28 |
Genentech, Inc. |
N-substituted benzamides and their use in the treatment of pain
|
AU2013270681A1
(en)
|
2012-06-08 |
2014-12-18 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions for the treatment of CFTR -mediated disorders
|
WO2013185202A1
(en)
|
2012-06-14 |
2013-12-19 |
Beta Pharma Canada Inc |
Apoptosis inducers
|
WO2014008458A2
(en)
|
2012-07-06 |
2014-01-09 |
Genentech, Inc. |
N-substituted benzamides and methods of use thereof
|
US9012496B2
(en)
|
2012-07-16 |
2015-04-21 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions of (R)-1-(2,2-difluorobenzo[D][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide and administration thereof
|
JP2015178458A
(ja)
|
2012-07-25 |
2015-10-08 |
杏林製薬株式会社 |
ベンゼン環縮合含窒素5員複素環式化合物、またはその薬理学的に許容される塩
|
MX360172B
(es)
|
2012-08-13 |
2018-10-12 |
Abbvie Inc |
Agentes que inducen la apoptosis.
|
WO2014028968A1
(en)
|
2012-08-21 |
2014-02-27 |
Peter Maccallum Cancer Institute |
Perforin inhibiting benzenesulfonamide compounds, preparation and uses thereof
|
ES2889757T3
(es)
|
2012-09-06 |
2022-01-13 |
Plexxikon Inc |
Compuestos y procedimientos para la modulación de quinasas e indicaciones para estos
|
WO2014047427A2
(en)
|
2012-09-21 |
2014-03-27 |
Vanderbilt University |
Substituted benzofuran, benzothiophene and indole mcl-1 inhibitors
|
RS57831B2
(sr)
|
2012-11-02 |
2024-02-29 |
Vertex Pharma |
Farmaceutske kompozicije za lečenje bolesti posredovanih sa cftr
|
EP2917203B1
(en)
|
2012-11-02 |
2019-04-03 |
Dana-Farber Cancer Institute, Inc. |
Method for identifying myc inhibitors
|
RU2674249C2
(ru)
|
2012-11-05 |
2018-12-06 |
НэнтБайо, Инк. |
Замещенные производные индол-5-ола и их терапевтическое применение
|
US20150305334A1
(en)
|
2012-12-05 |
2015-10-29 |
Bayer Cropscience Ag |
Use of substituted 1-(aryl ethynyl)-, 1-(heteroaryl ethynyl)-, 1-(heterocyclyl ethynyl)- and 1-(cycloalkenyl ethynyl)-cyclohexanols as active agents against abiotic plant stress
|
CN104955327A
(zh)
|
2012-12-05 |
2015-09-30 |
拜尔农作物科学股份公司 |
取代的1-(芳基乙炔基)双环链烷醇、1-(杂芳基乙炔基)双环链烷醇、1-(杂环基乙炔基)双环链烷醇和1-(环烯基乙炔基)双环链烷醇作为对抗非生物植物胁迫的活性剂的用途
|
UA115576C2
(uk)
|
2012-12-06 |
2017-11-27 |
Байєр Фарма Акцієнгезелльшафт |
Похідні бензимідазолу як антагоністи ер4
|
GB201223265D0
(en)
|
2012-12-21 |
2013-02-06 |
Selvita Sa |
Novel benzimidazole derivatives as kinase inhibitors
|
WO2014109858A1
(en)
|
2013-01-14 |
2014-07-17 |
Amgen Inc. |
Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
|
ES2705247T3
(es)
|
2013-03-14 |
2019-03-22 |
Univ Columbia |
4-fenilpiperidinas, su preparación y uso
|
US9637450B2
(en)
|
2013-03-14 |
2017-05-02 |
The Trustees Of Columbia University In The City Of New York |
Octahydrocyclopentapyrroles, their preparation and use
|
HRP20220376T1
(hr)
|
2013-03-15 |
2022-07-22 |
Cyclerion Therapeutics, Inc. |
Sgc stimulatori
|
HUE038220T2
(hu)
|
2013-03-29 |
2018-10-29 |
Takeda Pharmaceuticals Co |
6-(5-Hidroxi-lH-pirazol-1-il)nikotinamid származékok és PHD inhibitorként való alkalmazásuk
|
BR112015027964B1
(pt)
|
2013-05-07 |
2023-01-10 |
Galapagos Nv |
Compostos moduladores do regulador de condutância transmembrana da fibrose cística (cftr), composições farmacêuticas compreendendo os mesmos e uso destes para o tratamento da fibrose cística
|
WO2014181287A1
(en)
|
2013-05-09 |
2014-11-13 |
Piramal Enterprises Limited |
Heterocyclyl compounds and uses thereof
|
WO2014190199A1
(en)
|
2013-05-24 |
2014-11-27 |
The California Institute For Biomedical Research |
Compounds for treatment of drug resistant and persistent tuberculosis
|
WO2015010832A1
(en)
|
2013-07-22 |
2015-01-29 |
Syngenta Participations Ag |
Microbiocidal heterocyclic derivatives
|
EP3038618B1
(en)
|
2013-08-28 |
2020-10-14 |
Vanderbilt University |
Substituted indole mcl-1 inhibitors
|
WO2015051043A1
(en)
|
2013-10-01 |
2015-04-09 |
Amgen Inc. |
Biaryl acyl-sulfonamide compounds as sodium channel inhibitors
|
WO2015069287A1
(en)
|
2013-11-08 |
2015-05-14 |
Allergan, Inc. |
Compounds as tyrosine kinase modulators
|
PL3068392T3
(pl)
|
2013-11-12 |
2021-07-19 |
Vertex Pharmaceuticals Incorporated |
Proces wytwarzania kompozycji farmaceutycznych do leczenia chorób, w których pośredniczy cftr
|
SI3131582T1
(sl)
|
2014-04-15 |
2018-09-28 |
Vertex Pharmaceuticals Incorporated |
Farmacevtski sestavki za zdravljenje bolezni, pri katerih posreduje regulator transmembranske prevodnosti
|
EP3798214B1
(en)
|
2014-10-06 |
2022-09-14 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
RU2749213C2
(ru)
|
2014-10-07 |
2021-06-07 |
Вертекс Фармасьютикалз Инкорпорейтед |
Сокристаллы модуляторов регулятора трансмембранной проводимости при кистозном фиброзе
|
JP6494757B2
(ja)
|
2014-11-18 |
2019-04-03 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
ハイスループット試験高速液体クロマトグラフィーを行うプロセス
|
MA41253A
(fr)
|
2014-12-23 |
2017-10-31 |
Proteostasis Therapeutics Inc |
Composés, compositions et procédés pour augmenter l'activité du cftr
|
WO2016105484A1
(en)
|
2014-12-23 |
2016-06-30 |
Proteostasis Therapeutics, Inc. |
Derivatives of 5-(hetero)arylpyrazol-3-carboxylic amide or 1-(hetero)aryltriazol-4-carboxylic amide useful for the treatment of inter alia cystic fibrosis
|
WO2016128529A1
(en)
*
|
2015-02-15 |
2016-08-18 |
F. Hoffmann-La Roche Ag |
1-(het)arylsulfonyl-(pyrrolidine or piperidine)-2-carboxamide derivatives and their use as trpa1 antagonists
|
US10196384B2
(en)
|
2015-03-31 |
2019-02-05 |
Vertex Pharmaceuticals (Europe) Limited |
Deuterated CFTR modulators
|
AU2016326441B2
(en)
|
2015-09-21 |
2021-11-25 |
Vertex Pharmaceuticals (Europe) Limited |
Administration of deuterated CFTR potentiators
|
EP3436432B1
(en)
|
2016-03-30 |
2021-01-27 |
Genentech, Inc. |
Substituted benzamides and methods of use thereof
|
CA3019380A1
(en)
|
2016-03-31 |
2017-10-05 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
NZ746793A
(en)
|
2016-04-07 |
2022-10-28 |
Proteostasis Therapeutics Inc |
Silicone atoms containing ivacaftor analogues
|
CA3016303A1
(en)
|
2016-04-26 |
2017-11-02 |
Abbvie S.A.R.L. |
Modulators of cystic fibrosis transmembrane conductance regulator protein
|
US10138227B2
(en)
|
2016-06-03 |
2018-11-27 |
Abbvie S.Á.R.L. |
Heteroaryl substituted pyridines and methods of use
|
US10899751B2
(en)
|
2016-06-21 |
2021-01-26 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions, and methods for increasing CFTR activity
|
ES2900263T3
(es)
|
2016-09-30 |
2022-03-16 |
Vertex Pharma |
Modulador de regulador de conductancia transmembrana de fibrosis quística, composiciones farmacéuticas, métodos de tratamiento y proceso de fabricación del modulador
|
US10399940B2
(en)
|
2016-10-07 |
2019-09-03 |
Abbvie S.Á.R.L. |
Substituted pyrrolidines and methods of use
|
US9981910B2
(en)
|
2016-10-07 |
2018-05-29 |
Abbvie S.Á.R.L. |
Substituted pyrrolidines and methods of use
|
US20190256474A1
(en)
|
2016-10-26 |
2019-08-22 |
Proteostasis Therapeutics, Inc. |
N-phenyl-2-(3-phenyl-6-oxo-1,6-dihydropyridazin-1-yl)acetamide derivatives for treating cystic fibrosis
|
AU2017348186A1
(en)
|
2016-10-26 |
2019-05-16 |
Proteostasis Therapeutics, Inc |
Pyridazine derivatives, compositions and methods for modulating CFTR
|
WO2018081378A1
(en)
|
2016-10-26 |
2018-05-03 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions, and methods for modulating cftr
|
SG10202106949XA
(en)
|
2016-11-18 |
2021-07-29 |
Cystic Fibrosis Found |
Pyrrolopyrimidines as cftr potentiators
|
JOP20190125B1
(ar)
|
2016-12-09 |
2022-03-14 |
Vertex Pharma |
مُعدِّل لمنظم موصلية التليف الكيسي عبر الغشاء، وتركيبات صيدلانية، وطرق للعلاج، وعملية لتصنيع المُعدِّل
|
WO2018112149A1
(en)
|
2016-12-16 |
2018-06-21 |
Cystic Fibrosis Foundaton Therapeutics Inc. |
Bycyclic heteroaryl derivatives as cftr potentiators
|
US20200123137A1
(en)
|
2016-12-20 |
2020-04-23 |
AbbVie S.à.r.l. |
Deuterated cftr modulators and methods of use
|
WO2018127130A1
(en)
|
2017-01-07 |
2018-07-12 |
Shanghai Fochon Pharmaceutical Co., Ltd. |
Compounds as bcl-2-selective apoptosis-inducing agents
|
TW201831471A
(zh)
|
2017-02-24 |
2018-09-01 |
盧森堡商艾伯維公司 |
囊腫纖化症跨膜傳導調節蛋白的調節劑及其使用方法
|
US20180280349A1
(en)
|
2017-03-28 |
2018-10-04 |
Vertex Pharmaceuticals Incorporated |
Methods of treating cystic fibrosis in patients with residual function mutations
|
EP3615528B1
(en)
|
2017-04-28 |
2022-02-16 |
Proteostasis Therapeutics, Inc. |
4-sulfonylaminocarbonylquinoline derivatives for increasing cftr activity
|
CA3066084A1
(en)
|
2017-06-08 |
2018-12-13 |
Vertex Pharmaceuticals Incorporated |
Methods of treatment for cystic fibrosis
|
WO2019010092A1
(en)
|
2017-07-01 |
2019-01-10 |
Vertex Pharmaceuticals Incorporated |
COMPOSITIONS AND METHODS FOR TREATING CYSTIC FIBROSIS
|
US20200171015A1
(en)
|
2017-07-17 |
2020-06-04 |
Vertex Pharmaceuticals Incorporated |
Methods of treatment for cystic fibrosis
|
EP3654969A1
(en)
|
2017-07-17 |
2020-05-27 |
Vertex Pharmaceuticals Incorporated |
Methods of treatment for cystic fibrosis
|
WO2019026075A1
(en)
|
2017-07-31 |
2019-02-07 |
Technion Research & Development Foundation Limited |
METHODS OF DETECTING MODIFIED AND UN-MODIFIED DNA
|
TWI799435B
(zh)
|
2017-08-02 |
2023-04-21 |
美商維泰克斯製藥公司 |
製備化合物之製程
|
US10988454B2
(en)
|
2017-09-14 |
2021-04-27 |
Abbvie Overseas S.À.R.L. |
Modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
|
WO2019071078A1
(en)
|
2017-10-06 |
2019-04-11 |
Proteostasis Therapeutics, Inc. |
COMPOUNDS, COMPOSITIONS AND METHODS FOR INCREASING CFTR ACTIVITY
|
CA3078893A1
(en)
|
2017-10-19 |
2019-04-25 |
Vertex Pharmaceuticals Incorporated |
Crystalline forms and compositions of cftr modulators
|
US20210228489A1
(en)
|
2017-12-04 |
2021-07-29 |
Vertex Pharmaceuticals Incorporated |
Compositions for treating cystic fibrosis
|
EP3720849A2
(en)
|
2017-12-08 |
2020-10-14 |
Vertex Pharmaceuticals Incorporated |
Processes for making modulators of cystic fibrosis transmembrane conductance regulator
|
TWI810243B
(zh)
|
2018-02-05 |
2023-08-01 |
美商維泰克斯製藥公司 |
用於治療囊腫纖化症之醫藥組合物
|
US20210009560A1
(en)
|
2018-03-30 |
2021-01-14 |
Vertex Pharmaceuticals Incorporated |
Crystalline forms of modulators of cftr
|
WO2019195739A1
(en)
|
2018-04-05 |
2019-10-10 |
Alexander Russell Abela |
Modulators of cystic fibrosis transmembrane conductance regulator
|
EP3774825A1
(en)
|
2018-04-13 |
2021-02-17 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator, pharmaceutical compositions, methods of treatment, and process for making the modulator
|
WO2020214921A1
(en)
|
2019-04-17 |
2020-10-22 |
Vertex Pharmaceuticals Incorporated |
Solid forms of modulators of cftr
|
WO2020242935A1
(en)
|
2019-05-29 |
2020-12-03 |
Vertex Pharmaceuticals Incorporated |
Methods of treatment for cystic fibrosis
|
EP4013760A1
(en)
|
2019-08-14 |
2022-06-22 |
Vertex Pharmaceuticals Incorporated |
Crystalline forms of cftr modulators
|
TW202120517A
(zh)
|
2019-08-14 |
2021-06-01 |
美商維泰克斯製藥公司 |
製備cftr調節劑之方法
|
TW202115092A
(zh)
|
2019-08-14 |
2021-04-16 |
美商維泰克斯製藥公司 |
囊腫纖維化跨膜傳導調節蛋白之調節劑
|
EP4013759A1
(en)
|
2019-08-14 |
2022-06-22 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|