JP2006510556A - メラトニン−日用量ユニット - Google Patents
メラトニン−日用量ユニット Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
- A61K8/4913—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid
- A61K8/492—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having five membered rings, e.g. pyrrolidone carboxylic acid having condensed rings, e.g. indol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
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- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
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- A61J1/067—Flexible ampoules, the contents of which are expelled by squeezing
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4188—1,3-Diazoles condensed with other heterocyclic ring systems, e.g. biotin, sorbinil
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
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- A61K36/16—Ginkgophyta, e.g. Ginkgoaceae (Ginkgo family)
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
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- A61K8/673—Vitamin B group
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- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9771—Ginkgophyta, e.g. Ginkgoaceae [Ginkgo family]
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- A—HUMAN NECESSITIES
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- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M35/00—Devices for applying media, e.g. remedies, on the human body
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- A—HUMAN NECESSITIES
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/87—Application Devices; Containers; Packaging
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Public Health (AREA)
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- Pharmacology & Pharmacy (AREA)
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- Natural Medicines & Medicinal Plants (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
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- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicinal Preparation (AREA)
- Indole Compounds (AREA)
Abstract
Description
例1:作用物質メラトニン、イチョウおよびビオチンを有する本発明による調製物の組成物。
例1に記載された組成物を確率化された二重空試験においてプラシーボ対照と交叉試験計画法で8人の健康な女性の患者について試験した。日用量は、メラトニン0.1mgであり(組成物3ml)、これは、14日間毎日、就寝前に頭皮に塗布された。
Claims (29)
- 局所的に有効な用量に相当するが、しかし、体系的な作用を引き起こさない、メラトニンまたはメラトニン誘導体の単独用量を含有する局所的適用のための医薬品または化粧薬品のための使い捨て容器。
- メラトニンまたはメラトニン誘導体の単独用量が、0.001〜1.0mgである、請求項1記載の容器。
- メラトニンまたはメラトニン誘導体の単独用量が、0.01〜0.2mgである、請求項1または2記載の容器。
- 単独用量が日用量に相応する、請求項1から3までのいずれか1項に記載の容器。
- 薬品が液状調製物として存在する、請求項1から4までのいずれか1項に記載の容器。
- 液状調製物がメラトニン0.001〜0.01%(質量)の濃度を有する、請求項5記載の容器。
- 液状調製物がメラトニン0.003〜0.004%(質量)の濃度を有する、請求項6記載の容器。
- 薬品が唯一の作用物質としてメラトニンまたはメラトニン誘導体を含有する、請求項1から7までのいずれか1項に記載の容器。
- 薬品が作用物質としてメラトニンまたはメラトニン誘導体とビオチンまたは/およびイチョウとの組合せ物を含有する、請求項1から7までのいずれか1項に記載の容器。
- 薬品が作用物質としてメラトニンまたはメラトニン誘導体とビタミンA、ビタミンA−酸またはビタミンAの別の誘導体との組合せ物を含有する、請求項1から7までのいずれか1項に記載の容器。
- 容器が薬品2.5〜3.5mlを有する、請求項1から10までのいずれか1項に記載の容器。
- 容器が薬品2.9〜3.2mlを有する、請求項11記載の容器。
- 薬品がGMP条件下で注入されている、請求項1から12までのいずれか1項に記載の容器。
- 容器がプラスチックからなる、請求項1から13までのいずれか1項に記載の容器。
- 容器がポリエチレン、ポリプロピレン、ポリ塩化ビニル、ポリスチレンまたはこれらの混合物からなる、請求項14記載の容器。
- 容器が無色である、請求項1から15までのいずれか1項に記載の容器。
- 容器が有色である、請求項1から15までのいずれか1項に記載の容器。
- 容器が透明である、請求項1から17までのいずれか1項に記載の容器。
- 容器が非透明である、請求項1から17までのいずれか1項に記載の容器。
- 容器が回転によって開放することができる使い捨て栓を頭部に有する、請求項1から19までのいずれか1項に記載の容器。
- 開放後に薬品が使用の場合にのみ圧力によって流出する、請求項1から20までのいずれか1項に記載の容器。
- 容器が印刷または刻印によって説明されているかまたは/およびラベルが貼られている、請求項1から21までのいずれか1項に記載の容器。
- 請求項1から22までのいずれか1項に記載の互いに分離可能に結合されている多数の容器を備えたユニット。
- 5個の容器が互いに分離可能に結合されている、請求項23記載のユニット。
- 10個の容器が互いに分離可能に結合されている、請求項23記載のユニット。
- ユニットがアルミニウム袋中に包装されている、請求項23から25までのいずれか1項に記載のユニット。
- 前記袋がアルミニウムを含有する貼り合わせフィルムからなり、付加的にポリエチレン、ポリエステルまたは/および紙を含む、請求項26記載のユニット。
- アルミニウム袋に印刷がなされているかまたは/およびラベルが貼られている、請求項26または27記載のユニット。
- 請求項23から28までのいずれか1項に記載の多数のユニットを含む包装品ユニット。
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10250646A DE10250646A1 (de) | 2002-10-30 | 2002-10-30 | Melatonin in kosmetischen Formulierungen |
DE20217814U DE20217814U1 (de) | 2002-11-18 | 2002-11-18 | Melatonin-Tagesdosierungseinheiten |
US10/353,056 US20040094449A1 (en) | 2002-11-18 | 2003-01-29 | Melatonin daily dosage units |
PCT/EP2003/012099 WO2004039369A1 (de) | 2002-10-30 | 2003-10-30 | Melatonin-tagesdosierungseinheiten |
Publications (1)
Publication Number | Publication Date |
---|---|
JP2006510556A true JP2006510556A (ja) | 2006-03-30 |
Family
ID=32233793
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005501814A Pending JP2006513255A (ja) | 2002-10-30 | 2003-10-30 | メラトニン、イチョウおよびビオチンを含有する調製物 |
JP2005501815A Pending JP2006510556A (ja) | 2002-10-30 | 2003-10-30 | メラトニン−日用量ユニット |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2005501814A Pending JP2006513255A (ja) | 2002-10-30 | 2003-10-30 | メラトニン、イチョウおよびビオチンを含有する調製物 |
Country Status (21)
Country | Link |
---|---|
US (3) | US20060035924A1 (ja) |
EP (2) | EP1562585B2 (ja) |
JP (2) | JP2006513255A (ja) |
KR (2) | KR100849916B1 (ja) |
CN (2) | CN1708331A (ja) |
AT (1) | ATE419038T1 (ja) |
AU (2) | AU2003278164A1 (ja) |
BR (2) | BR0315878A (ja) |
CA (2) | CA2504341A1 (ja) |
DE (1) | DE50311024D1 (ja) |
DK (1) | DK1569724T3 (ja) |
EC (2) | ECSP055820A (ja) |
ES (1) | ES2315541T3 (ja) |
HR (2) | HRP20050385A2 (ja) |
IS (1) | IS7820A (ja) |
MX (2) | MXPA05004535A (ja) |
NO (2) | NO334680B1 (ja) |
NZ (2) | NZ539871A (ja) |
PL (2) | PL212984B1 (ja) |
SI (1) | SI1569724T1 (ja) |
WO (2) | WO2004039369A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2018538062A (ja) * | 2015-12-09 | 2018-12-27 | トキタエ エルエルシー | 多連単回用量容器のパッケージング |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102698273A (zh) | 2004-12-24 | 2012-10-03 | 都菲斯特股份有限公司 | 毛发学制剂和毛发学治疗 |
GB0513581D0 (en) | 2005-07-01 | 2005-08-10 | Norton Healthcare Ltd | Container |
ITGE20070009A1 (it) * | 2007-01-24 | 2008-07-25 | Leila Baeram | Composizione cosmetica e metodo per favorire la ricrescita dei capelli. |
US8940326B2 (en) | 2007-03-19 | 2015-01-27 | Vita Sciences Llc | Transdermal patch and method for delivery of vitamin B12 |
WO2008148015A1 (en) * | 2007-05-24 | 2008-12-04 | The Trustees Of Columbia University In The City Of New York | Sustained release formulation of melatonin |
IT1392903B1 (it) * | 2008-07-29 | 2012-04-02 | Marino Salin | Composizione comprendente un'associazione di principi attivi per uso nel trattamento topico della calvizie |
US9393182B2 (en) * | 2008-11-18 | 2016-07-19 | Scarguard Labs, Llc | Anti-aging product |
IT1401173B1 (it) * | 2010-07-26 | 2013-07-12 | Lameplast Spa | Contenitore richiudibile per prodotti fluidi, particolarmente per prodotti medicali, farmaceutici e cosmetici |
US11696883B2 (en) | 2014-05-23 | 2023-07-11 | Triple Hair Inc. | Compositions for reducing hair loss and/or increasing hair regrowth |
PL3062797T3 (pl) | 2014-05-23 | 2020-08-24 | Triple Hair Inc. | Kompozycje zmniejszające wypadanie włosów i/lub zwiększające odrastanie włosów |
KR101622387B1 (ko) * | 2015-01-30 | 2016-05-20 | 현대약품 주식회사 | 멜라토닌을 포함하는 안정성이 개선된 육모, 양모 또는 발모 촉진용 조성물 |
US10342735B2 (en) | 2015-06-11 | 2019-07-09 | Tokitae Llc | Multi-monodose containers |
US20160361232A1 (en) | 2015-06-11 | 2016-12-15 | Tokitae Llc | Packaging Multi-Monodose Containers |
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JP2018538062A (ja) * | 2015-12-09 | 2018-12-27 | トキタエ エルエルシー | 多連単回用量容器のパッケージング |
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