IL160847A0 - A hydrate of substituted thiazolidinedione derivative, process for its preparation and pharmaceutical composition comprising the same - Google Patents

A hydrate of substituted thiazolidinedione derivative, process for its preparation and pharmaceutical composition comprising the same

Info

Publication number
IL160847A0
IL160847A0 IL16084798A IL16084798A IL160847A0 IL 160847 A0 IL160847 A0 IL 160847A0 IL 16084798 A IL16084798 A IL 16084798A IL 16084798 A IL16084798 A IL 16084798A IL 160847 A0 IL160847 A0 IL 160847A0
Authority
IL
Israel
Prior art keywords
hydrate
preparation
pharmaceutical composition
same
thiazolidinedione derivative
Prior art date
Application number
IL16084798A
Other languages
English (en)
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of IL160847A0 publication Critical patent/IL160847A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL16084798A 1997-12-16 1998-12-14 A hydrate of substituted thiazolidinedione derivative, process for its preparation and pharmaceutical composition comprising the same IL160847A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9726563.1A GB9726563D0 (en) 1997-12-16 1997-12-16 Novel pharmaceutical
PCT/EP1998/008153 WO1999031093A1 (en) 1997-12-16 1998-12-14 Substituted thiazolidinedione derivative, process for its preparation and its pharmaceutical use
IL13642598A IL136425A (en) 1997-12-16 1998-12-14 Transformed hydrolyzed thiazolidinedione, its preparation process and pharmaceutical preparations containing it

Publications (1)

Publication Number Publication Date
IL160847A0 true IL160847A0 (en) 2004-08-31

Family

ID=10823691

Family Applications (2)

Application Number Title Priority Date Filing Date
IL16084798A IL160847A0 (en) 1997-12-16 1998-12-14 A hydrate of substituted thiazolidinedione derivative, process for its preparation and pharmaceutical composition comprising the same
IL13642598A IL136425A (en) 1997-12-16 1998-12-14 Transformed hydrolyzed thiazolidinedione, its preparation process and pharmaceutical preparations containing it

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL13642598A IL136425A (en) 1997-12-16 1998-12-14 Transformed hydrolyzed thiazolidinedione, its preparation process and pharmaceutical preparations containing it

Country Status (37)

Country Link
US (4) US20020133016A1 (xx)
EP (1) EP1042321A1 (xx)
JP (1) JP2002508371A (xx)
KR (1) KR100549141B1 (xx)
CN (3) CN101318957A (xx)
AP (1) AP1363A (xx)
AR (2) AR017211A1 (xx)
AU (2) AU2272299A (xx)
BG (1) BG64850B1 (xx)
BR (1) BR9813598A (xx)
CA (1) CA2314967A1 (xx)
CO (1) CO4990943A1 (xx)
CZ (1) CZ300081B6 (xx)
DZ (1) DZ2679A1 (xx)
EA (1) EA002833B1 (xx)
EG (1) EG22250A (xx)
GB (1) GB9726563D0 (xx)
HR (1) HRP20000404A2 (xx)
HU (1) HUP0102292A3 (xx)
ID (1) ID24714A (xx)
IL (2) IL160847A0 (xx)
MA (1) MA26581A1 (xx)
MY (1) MY128573A (xx)
NO (1) NO317255B1 (xx)
NZ (1) NZ504703A (xx)
OA (1) OA11900A (xx)
PE (1) PE20000125A1 (xx)
PL (1) PL341213A1 (xx)
RS (1) RS50080B (xx)
SA (1) SA99200200B1 (xx)
SK (1) SK286422B6 (xx)
TR (2) TR200001793T2 (xx)
TW (1) TW487709B (xx)
UA (1) UA66821C2 (xx)
UY (2) UY25309A1 (xx)
WO (1) WO1999031093A1 (xx)
ZA (1) ZA9811504B (xx)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39384E1 (en) 1993-09-01 2006-11-07 Smithkline Beecham P.L.C. Substituted thiazolidinedione derivatives
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
GB9726568D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9909041D0 (en) * 1999-04-20 1999-06-16 Smithkline Beecham Plc Novel pharmaceutical
KR100744359B1 (ko) * 1999-04-23 2007-07-30 스미스클라인비이참피이엘시이 티아졸리딘디온 유도체 및 항당뇨병제로서 그의 용도
TR200103060T2 (tr) * 1999-04-23 2002-05-21 Smithkline Beecham P. L. C. Yeni farmasötik maddeler
US20040248945A1 (en) 1999-04-23 2004-12-09 Smithkline Beecham P.L.C. Thiazolidinedione derivative and its use as antidiabetic
ATE246191T1 (de) 1999-04-23 2003-08-15 Smithkline Beecham Plc Polymorph von 5-(4-(2-(n-methyl-n-(2- pyrdyl)amino)äthoxy)benzyl)thiazolidin-2,4-dion maleinsäuresalz
GB0014005D0 (en) * 2000-06-08 2000-08-02 Smithkline Beecham Plc Novel pharmaceutical
GB0021784D0 (en) * 2000-09-05 2000-10-18 Smithkline Beecham Plc Novel pharmaceutical
GB0021978D0 (en) * 2000-09-07 2000-10-25 Smithkline Beecham Plc Novel pharmaceutical
GB0129876D0 (en) * 2001-12-13 2002-02-06 Smithkline Beecham Plc Novel pharmaceutical
WO2003050112A1 (en) * 2001-12-13 2003-06-19 Smithkline Beecham Plc Toluenesulfonate hydrates of a thiazolidinedione derivative
KR100450700B1 (ko) * 2002-03-22 2004-10-01 주식회사종근당 티아졸리딘디온 유도체 화합물 및 이를 함유하는 약제학적조성물
EP1468997A3 (en) * 2003-04-18 2004-11-03 CHEMI S.p.A. Polymorphous forms of rosiglitazone maleate
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
US20050163842A1 (en) * 2003-12-31 2005-07-28 Garth Boehm Rosiglitazone and metformin formulations
WO2005065654A2 (en) * 2003-12-31 2005-07-21 Alpharma, Inc. Rosiglitazone formulations
ITMI20041537A1 (it) * 2004-07-28 2004-10-28 Chemi Spa Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
US7435741B2 (en) * 2006-05-09 2008-10-14 Teva Pharmaceutical Industries, Ltd. 2-N{5-[[4-[2-(methyl-2-pyridinylamino) ethoxy] phenyl]methyl]-2,4-thiazolidinedione} butanedioic acid, methods of preparation and compositions with rosiglitazone maleate
EP2184055A1 (en) 2008-11-07 2010-05-12 LEK Pharmaceuticals d.d. Process for preparing solid dosage forms of rosiglitazone maleate

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3856378T2 (de) 1987-09-04 2000-05-11 Beecham Group Plc Substituierte Thiazolidindionderivate
US6288095B1 (en) 1987-09-04 2001-09-11 Beecham Group P.L.C. Compounds
GB8820389D0 (en) * 1988-08-26 1988-09-28 Beecham Group Plc Novel compounds
GB9124513D0 (en) * 1991-11-19 1992-01-08 Smithkline Beecham Plc Novel process
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
US5741803A (en) 1992-09-05 1998-04-21 Smithkline Beecham Plc Substituted thiazolidinedionle derivatives
SG47100A1 (en) * 1994-02-10 1998-03-20 Smithkline Beecham Plc Use of insulin sensitisers for treating renal diseases
DE4404198A1 (de) 1994-02-10 1995-08-17 Henkel Kgaa 2-Fluor-6-nitroaniline
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
CA2426117A1 (en) 2000-09-26 2002-04-04 Dr. Reddy's Research Foundation Novel polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino]ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation

Also Published As

Publication number Publication date
CN101318956A (zh) 2008-12-10
HUP0102292A3 (en) 2003-12-29
CN1285831A (zh) 2001-02-28
EP1042321A1 (en) 2000-10-11
CZ300081B6 (cs) 2009-01-28
TR200001793T2 (tr) 2000-10-23
RS50080B (sr) 2009-01-22
US20050288513A1 (en) 2005-12-29
BG64850B1 (bg) 2006-06-30
PE20000125A1 (es) 2000-03-03
JP2002508371A (ja) 2002-03-19
DZ2679A1 (fr) 2003-03-29
AU2753802A (en) 2002-05-16
ZA9811504B (en) 2000-06-15
GB9726563D0 (en) 1998-02-11
UA66821C2 (uk) 2004-06-15
HRP20000404A2 (en) 2000-12-31
AU770818B2 (en) 2004-03-04
BR9813598A (pt) 2000-10-10
US20020133016A1 (en) 2002-09-19
TW487709B (en) 2002-05-21
YU36400A (sh) 2003-12-31
AU2272299A (en) 1999-07-05
OA11900A (en) 2006-04-10
NO317255B1 (no) 2004-09-27
UY25306A1 (es) 2000-12-29
CN101318957A (zh) 2008-12-10
SK286422B6 (sk) 2008-09-05
EG22250A (en) 2002-11-30
NO20003070L (no) 2000-06-15
TR199802624A3 (tr) 1999-10-21
ID24714A (id) 2000-08-03
UY25309A1 (es) 1999-07-19
EA200000656A1 (ru) 2000-12-25
BG104606A (en) 2001-02-28
IL136425A (en) 2004-08-31
SA99200200B1 (ar) 2006-11-11
CO4990943A1 (es) 2000-12-26
US20030139604A1 (en) 2003-07-24
AP2000001829A0 (en) 2000-06-30
PL341213A1 (en) 2001-03-26
NZ504703A (en) 2002-12-20
SK9182000A3 (en) 2000-12-11
CA2314967A1 (en) 1999-06-24
US20070037859A1 (en) 2007-02-15
HUP0102292A2 (hu) 2002-05-29
MA26581A1 (fr) 2004-12-20
AP1363A (en) 2005-01-21
IL136425A0 (en) 2001-06-14
NO20003070D0 (no) 2000-06-15
WO1999031093A1 (en) 1999-06-24
CZ20002206A3 (cs) 2000-12-13
MY128573A (en) 2007-02-28
KR20010033140A (ko) 2001-04-25
TR199802624A2 (xx) 1999-10-21
US7368574B2 (en) 2008-05-06
EA002833B1 (ru) 2002-10-31
KR100549141B1 (ko) 2006-02-03
AR016161A1 (es) 2001-06-20
AR017211A1 (es) 2001-08-22

Similar Documents

Publication Publication Date Title
IL160847A0 (en) A hydrate of substituted thiazolidinedione derivative, process for its preparation and pharmaceutical composition comprising the same
IL135920A0 (en) 2-aryl -8-oxodihydropurine derivative, process for the preparation thereof, pharmaceutical composition containing the same and intermediate therefor
HUP0004024A3 (en) Azabenzimidazole-based compounds, process for their preparation and pharmaceutical composition thereof
IL174082A0 (en) Crystal modification of a n-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use for the preparation of a pharmaceutical composition
HUP0001539A3 (en) 2-(1-iminoethylamino)ethyl-homocysteine, process for its preparation and pharmaceutical compositions containing the same
HUP0100431A3 (en) Adamantana derivatives, pharmaceutical compositions comprising them and process for preparing them
HUP0001153A3 (en) Chemically modified polypeptides, process for producing thereof, pharmaceutical compositions comprising these polypeptides and their use
HUP0203542A3 (en) 3(5)-amino-pyrazole derivatives, process for their preparation, their use and pharmaceutical compositions containing the same
HUP0001508A3 (en) 4-arylmethylene-2-imino-2,3-dihydrothiazole derivatives, their use, process for the preparation thereof and pharmaceutical compositions containing them
HUP0102711A3 (en) Epothilone derivatives and pharmaceutical compositions containing them and process for preparation the same
AU7640696A (en) Thiazolidinedione derivatives, method for preparing the derivatives and pharmaceutical compositions containing same
HUP0001555A3 (en) Tetrahydro-imidazo-naphthyridine derivatives, pharmaceutical compositions thereof and process for their preparation
AU3031797A (en) New substituted 2,4-thiazolidinedione derivatives, processes for producing them and pharmaceutical compositions containing them
HUP9803040A3 (en) Thiazole derivatives, process for the preparation thereof, use thereof and pharmaceutical compositions containing them
IL113103A0 (en) Piperidine derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
HUP0100144A3 (en) Process for the preparation of thiazolidinedione derivatives
AU2002300593A1 (en) Process for the preparation of thiazolidinedione derivatives
HUP0001459A3 (en) Process for the preparation of substituted thiazolidinedione derivatives
HUP0004457A3 (en) Angiogenesis inhibiting thiadiazolyl-pyridazine derivatives, process for producing them and pharmaceutical compositions containing the same
HUP0003766A3 (en) Isoguinolin derivatives, process for producing them and pharmaceutical compositions containing them
HUP0104544A3 (en) New pharmaceutical composition and the process for its preparation
HUP0003997A3 (en) 3-benzylpiperidine derivatives, pharmaceutical compositions containing them and process for producing them
HUP9602324A3 (en) Piperidinyl-methyl-oxazolidinon derivatives, pharmaceutical compositions containing the same, process for the preparation of the compounds and use of them
HUP0003104A3 (en) Amino-spiropiperidin-quinazoline derivatives, their use, process for their preparation and pharmaceutical compositions containing them
HUP0001222A3 (en) Imino-aza-anthracyclinone derivatives, pharmaceutical compositions thereof against amyloidosis and process for preparing them