IL150755A0 - Uses of agonists and antagonists to modulate activity of tnf-related molecules - Google Patents
Uses of agonists and antagonists to modulate activity of tnf-related moleculesInfo
- Publication number
- IL150755A0 IL150755A0 IL15075500A IL15075500A IL150755A0 IL 150755 A0 IL150755 A0 IL 150755A0 IL 15075500 A IL15075500 A IL 15075500A IL 15075500 A IL15075500 A IL 15075500A IL 150755 A0 IL150755 A0 IL 150755A0
- Authority
- IL
- Israel
- Prior art keywords
- methods
- tnf
- agonists
- modulate activity
- antagonists
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18293800P | 2000-02-16 | 2000-02-16 | |
US22698600P | 2000-08-22 | 2000-08-22 | |
PCT/US2000/032378 WO2001060397A1 (en) | 2000-02-16 | 2000-11-28 | Uses of agonists and antagonists to modulate activity of tnf-related molecules |
Publications (1)
Publication Number | Publication Date |
---|---|
IL150755A0 true IL150755A0 (en) | 2003-02-12 |
Family
ID=26878566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15075500A IL150755A0 (en) | 2000-02-16 | 2000-11-28 | Uses of agonists and antagonists to modulate activity of tnf-related molecules |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060073146A1 (xx) |
EP (2) | EP1255558B1 (xx) |
JP (1) | JP5062606B2 (xx) |
AT (2) | ATE511857T1 (xx) |
AU (1) | AU2048501A (xx) |
CA (1) | CA2396793A1 (xx) |
CY (1) | CY1105212T1 (xx) |
DE (1) | DE60028830T2 (xx) |
DK (2) | DK1255558T3 (xx) |
ES (1) | ES2267593T3 (xx) |
HK (1) | HK1093674A1 (xx) |
IL (1) | IL150755A0 (xx) |
PT (1) | PT1255558E (xx) |
WO (1) | WO2001060397A1 (xx) |
Families Citing this family (55)
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EE05673B1 (et) † | 1999-08-17 | 2013-08-15 | Biogen, Inc. | BAFF-retseptor (BCMA), immunoregulatoorne agens |
UA74798C2 (uk) * | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
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EA016083B1 (ru) | 2005-08-09 | 2012-02-28 | Займоджинетикс, Инк. | СПОСОБ ЛЕЧЕНИЯ НЕХОДЖКИНСКОЙ ЛИМФОМЫ С ПОМОЩЬЮ СЛИТОЙ МОЛЕКУЛЫ TACI-Ig |
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WO2009062926A1 (en) * | 2007-11-12 | 2009-05-22 | Ares Trading S.A. | Taci-immunoglobulin fusion proteins for treatment of relapsing multiple sclerosis |
JP2011503035A (ja) * | 2007-11-12 | 2011-01-27 | アレス トレーディング ソシエテ アノニム | 視神経炎治療のためのtaci−免疫グロブリン融合タンパク質 |
EP2219675B1 (en) | 2007-11-12 | 2013-10-23 | Ares Trading S.A. | Formulations for taci-immunoglobulin fusion proteins |
AU2015201974B2 (en) * | 2009-03-02 | 2016-12-15 | Aduro Biotech Holdings, Europe B.V. | Antibodies against a proliferating inducing ligand (APRIL) |
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TW201302793A (zh) | 2010-09-03 | 2013-01-16 | Glaxo Group Ltd | 新穎之抗原結合蛋白 |
UA112434C2 (uk) | 2011-05-27 | 2016-09-12 | Ґлаксо Ґруп Лімітед | Антигензв'язувальний білок, який специфічно зв'язується з всма |
WO2013171296A1 (en) | 2012-05-16 | 2013-11-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Diagnostic and treatment of sarcoidosis |
EP2971077B1 (en) | 2013-03-15 | 2019-05-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Method and pharmaceutical composition for use in the treatment and prediction of myocardial infarction |
NL2011406C2 (en) | 2013-09-06 | 2015-03-10 | Bionovion Holding B V | Method for obtaining april-binding peptides, process for producing the peptides, april-binding peptides obtainable with said method/process and use of the april-binding peptides. |
US10435474B2 (en) | 2013-12-24 | 2019-10-08 | Ossianix, Inc. | Baff selective binding compounds and related methods |
EP3243831A1 (en) * | 2014-02-27 | 2017-11-15 | Ucl Business Plc | Variants of the proliferation-inducing ligand (april) |
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DK3380522T3 (da) | 2015-11-25 | 2024-01-22 | Visterra Inc | Antistofmolekyler til april og anvendelser deraf |
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CN116903727A (zh) | 2020-05-08 | 2023-10-20 | 高山免疫科学股份有限公司 | 具有和不具有t细胞抑制蛋白的april和baff抑制性免疫调节蛋白及其使用方法 |
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-
2000
- 2000-11-28 WO PCT/US2000/032378 patent/WO2001060397A1/en active IP Right Grant
- 2000-11-28 AT AT05025025T patent/ATE511857T1/de active
- 2000-11-28 IL IL15075500A patent/IL150755A0/xx unknown
- 2000-11-28 AU AU20485/01A patent/AU2048501A/en not_active Abandoned
- 2000-11-28 DE DE60028830T patent/DE60028830T2/de not_active Expired - Lifetime
- 2000-11-28 CA CA002396793A patent/CA2396793A1/en not_active Abandoned
- 2000-11-28 ES ES00983773T patent/ES2267593T3/es not_active Expired - Lifetime
- 2000-11-28 EP EP00983773A patent/EP1255558B1/en not_active Expired - Lifetime
- 2000-11-28 JP JP2001559493A patent/JP5062606B2/ja not_active Expired - Lifetime
- 2000-11-28 DK DK00983773T patent/DK1255558T3/da active
- 2000-11-28 EP EP05025025A patent/EP1666052B1/en not_active Expired - Lifetime
- 2000-11-28 AT AT00983773T patent/ATE329610T1/de active
- 2000-11-28 PT PT00983773T patent/PT1255558E/pt unknown
- 2000-11-28 DK DK05025025.7T patent/DK1666052T3/da active
-
2005
- 2005-02-28 US US11/069,473 patent/US20060073146A1/en not_active Abandoned
-
2006
- 2006-09-06 CY CY20061101276T patent/CY1105212T1/el unknown
- 2006-12-04 HK HK06113277.1A patent/HK1093674A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
US20060073146A1 (en) | 2006-04-06 |
WO2001060397A1 (en) | 2001-08-23 |
CY1105212T1 (el) | 2010-03-03 |
EP1255558B1 (en) | 2006-06-14 |
JP5062606B2 (ja) | 2012-10-31 |
DE60028830T2 (de) | 2007-01-18 |
DE60028830D1 (de) | 2006-07-27 |
JP2003522800A (ja) | 2003-07-29 |
WO2001060397A9 (en) | 2002-12-05 |
DK1255558T3 (da) | 2006-10-23 |
ES2267593T3 (es) | 2007-03-16 |
AU2048501A (en) | 2001-08-27 |
EP1666052B1 (en) | 2011-06-08 |
EP1255558A1 (en) | 2002-11-13 |
ATE329610T1 (de) | 2006-07-15 |
ATE511857T1 (de) | 2011-06-15 |
EP1666052A1 (en) | 2006-06-07 |
DK1666052T3 (da) | 2011-09-12 |
CA2396793A1 (en) | 2001-08-23 |
PT1255558E (pt) | 2006-11-30 |
HK1093674A1 (en) | 2007-03-09 |
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