ATE329610T1 - Anti-april antikörper und hybridomazellen - Google Patents
Anti-april antikörper und hybridomazellenInfo
- Publication number
- ATE329610T1 ATE329610T1 AT00983773T AT00983773T ATE329610T1 AT E329610 T1 ATE329610 T1 AT E329610T1 AT 00983773 T AT00983773 T AT 00983773T AT 00983773 T AT00983773 T AT 00983773T AT E329610 T1 ATE329610 T1 AT E329610T1
- Authority
- AT
- Austria
- Prior art keywords
- methods
- april
- hybridoma cells
- taci
- bcma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2875—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
- C07K2319/43—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation containing a FLAG-tag
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US18293800P | 2000-02-16 | 2000-02-16 | |
US22698600P | 2000-08-22 | 2000-08-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE329610T1 true ATE329610T1 (de) | 2006-07-15 |
Family
ID=26878566
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00983773T ATE329610T1 (de) | 2000-02-16 | 2000-11-28 | Anti-april antikörper und hybridomazellen |
AT05025025T ATE511857T1 (de) | 2000-02-16 | 2000-11-28 | Anti-april monoklonaler antikörper und deren verwendung zur behandlung von immunerkrankungen oder krebs |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05025025T ATE511857T1 (de) | 2000-02-16 | 2000-11-28 | Anti-april monoklonaler antikörper und deren verwendung zur behandlung von immunerkrankungen oder krebs |
Country Status (14)
Country | Link |
---|---|
US (1) | US20060073146A1 (de) |
EP (2) | EP1666052B1 (de) |
JP (1) | JP5062606B2 (de) |
AT (2) | ATE329610T1 (de) |
AU (1) | AU2048501A (de) |
CA (1) | CA2396793A1 (de) |
CY (1) | CY1105212T1 (de) |
DE (1) | DE60028830T2 (de) |
DK (2) | DK1255558T3 (de) |
ES (1) | ES2267593T3 (de) |
HK (1) | HK1093674A1 (de) |
IL (1) | IL150755A0 (de) |
PT (1) | PT1255558E (de) |
WO (1) | WO2001060397A1 (de) |
Families Citing this family (55)
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US6541224B2 (en) | 1996-03-14 | 2003-04-01 | Human Genome Sciences, Inc. | Tumor necrosis factor delta polypeptides |
US6812327B1 (en) | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
US8212004B2 (en) | 1999-03-02 | 2012-07-03 | Human Genome Sciences, Inc. | Neutrokine-alpha fusion proteins |
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UA74798C2 (uk) * | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
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EP2281843B1 (de) * | 2000-06-16 | 2016-10-12 | Human Genome Sciences, Inc. | Immunspezifisch bindende antikörper gegen BLyS |
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US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
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US8211649B2 (en) | 2006-03-31 | 2012-07-03 | Human Genome Sciences, Inc. | Methods of diagnosing and prognosing hodgkin's lymphoma |
US8784812B2 (en) | 2006-05-15 | 2014-07-22 | Zymogenetics, Inc. | Methods for treating autoimmune diseases using a TACI-Ig fusion molecule |
US8852591B2 (en) * | 2007-03-27 | 2014-10-07 | Zymogenetics, Inc. | Combination of BLyS and/or APRIL inhibition and immunosuppressants for treatment of autoimmune disease |
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2000
- 2000-11-28 DE DE60028830T patent/DE60028830T2/de not_active Expired - Lifetime
- 2000-11-28 DK DK00983773T patent/DK1255558T3/da active
- 2000-11-28 CA CA002396793A patent/CA2396793A1/en not_active Abandoned
- 2000-11-28 JP JP2001559493A patent/JP5062606B2/ja not_active Expired - Lifetime
- 2000-11-28 EP EP05025025A patent/EP1666052B1/de not_active Expired - Lifetime
- 2000-11-28 PT PT00983773T patent/PT1255558E/pt unknown
- 2000-11-28 AT AT00983773T patent/ATE329610T1/de active
- 2000-11-28 WO PCT/US2000/032378 patent/WO2001060397A1/en active IP Right Grant
- 2000-11-28 ES ES00983773T patent/ES2267593T3/es not_active Expired - Lifetime
- 2000-11-28 IL IL15075500A patent/IL150755A0/xx unknown
- 2000-11-28 AT AT05025025T patent/ATE511857T1/de active
- 2000-11-28 DK DK05025025.7T patent/DK1666052T3/da active
- 2000-11-28 AU AU20485/01A patent/AU2048501A/en not_active Abandoned
- 2000-11-28 EP EP00983773A patent/EP1255558B1/de not_active Expired - Lifetime
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2005
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Also Published As
Publication number | Publication date |
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DK1666052T3 (da) | 2011-09-12 |
CA2396793A1 (en) | 2001-08-23 |
EP1666052A1 (de) | 2006-06-07 |
ES2267593T3 (es) | 2007-03-16 |
EP1255558B1 (de) | 2006-06-14 |
HK1093674A1 (en) | 2007-03-09 |
WO2001060397A1 (en) | 2001-08-23 |
WO2001060397A9 (en) | 2002-12-05 |
AU2048501A (en) | 2001-08-27 |
DK1255558T3 (da) | 2006-10-23 |
ATE511857T1 (de) | 2011-06-15 |
PT1255558E (pt) | 2006-11-30 |
US20060073146A1 (en) | 2006-04-06 |
IL150755A0 (en) | 2003-02-12 |
JP5062606B2 (ja) | 2012-10-31 |
JP2003522800A (ja) | 2003-07-29 |
EP1255558A1 (de) | 2002-11-13 |
EP1666052B1 (de) | 2011-06-08 |
DE60028830T2 (de) | 2007-01-18 |
DE60028830D1 (de) | 2006-07-27 |
CY1105212T1 (el) | 2010-03-03 |
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