HRP20000480B1 - Synthetic polysaccharides, their method of production and pharmaceutical compositions containing the same - Google Patents

Synthetic polysaccharides, their method of production and pharmaceutical compositions containing the same

Info

Publication number: HRP20000480B1
Authority: HR; Croatia
Prior art keywords: production; same; pharmaceutical compositions; compositions containing; synthetic polysaccharides
Prior art date: 1998-01-19

Application number

HR970630A

Other languages

English (en)

Inventor

Johannes Basten

Cornelia Dreef-Tromp

Pierre-Alexandre Driguez

Philippe Duchaussoy

Jean-Marc Herbert

Maurice Petitou

Constant Van Boeckel

Original Assignee

Sanofi Synthelabo

Akzo Nobel Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-01-19

Filing date

2000-07-19

Publication date

2002-04-30

2000-07-19 Application filed by Sanofi Synthelabo, Akzo Nobel Nv filed Critical Sanofi Synthelabo

2000-12-31 Publication of HRP20000480A2 publication Critical patent/HRP20000480A2/hr

2002-04-30 Publication of HRP20000480B1 publication Critical patent/HRP20000480B1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Polymers & Plastics (AREA)
Materials Engineering (AREA)
Diabetes (AREA)
Hematology (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Epidemiology (AREA)
Dermatology (AREA)
Vascular Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Medicinal Preparation (AREA)

HR970630A 1998-01-19 2000-07-19 Synthetic polysaccharides, their method of production and pharmaceutical compositions containing the same HRP20000480B1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9800515A FR2773804B1 (fr)	1998-01-19	1998-01-19	Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant
PCT/FR1999/000044 WO1999036443A1 (fr)	1998-01-19	1999-01-13	Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant

Publications (2)

Publication Number	Publication Date
HRP20000480A2 HRP20000480A2 (en)	2000-12-31
HRP20000480B1 true HRP20000480B1 (en)	2002-04-30

Family

ID=9521914

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HR970630A HRP20000480B1 (en)	1998-01-19	2000-07-19	Synthetic polysaccharides, their method of production and pharmaceutical compositions containing the same

Country Status (41)

Country	Link
US (1)	US6528497B1 (no)
EP (1)	EP1049721B1 (no)
JP (1)	JP4402835B2 (no)
KR (1)	KR100513196B1 (no)
CN (1)	CN1165550C (no)
AR (1)	AR013019A1 (no)
AT (1)	ATE209219T1 (no)
AU (1)	AU741748B2 (no)
BR (1)	BRPI9907025B8 (no)
CA (1)	CA2317465C (no)
CO (1)	CO4970795A1 (no)
CZ (1)	CZ297815B6 (no)
DE (1)	DE69900718T2 (no)
DK (1)	DK1049721T3 (no)
DZ (1)	DZ2709A1 (no)
EE (1)	EE04157B1 (no)
EG (1)	EG23982A (no)
ES (1)	ES2168000T3 (no)
FR (1)	FR2773804B1 (no)
GT (1)	GT199900003A (no)
HK (1)	HK1030002A1 (no)
HR (1)	HRP20000480B1 (no)
HU (1)	HU228333B1 (no)
IL (1)	IL137241A0 (no)
MA (1)	MA26597A1 (no)
MY (1)	MY119090A (no)
NO (1)	NO329903B1 (no)
NZ (1)	NZ505492A (no)
PE (1)	PE20000269A1 (no)
PL (1)	PL202802B1 (no)
PT (1)	PT1049721E (no)
RU (1)	RU2211224C2 (no)
SA (1)	SA99191113B1 (no)
SI (1)	SI1049721T1 (no)
SK (1)	SK283411B6 (no)
TR (1)	TR200002078T2 (no)
TW (1)	TW548279B (no)
UA (1)	UA60352C2 (no)
UY (1)	UY25356A1 (no)
WO (1)	WO1999036443A1 (no)
ZA (1)	ZA99355B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2814463B1 (fr) *	2000-09-22	2002-11-15	Sanofi Synthelabo	Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
FR2874924B1 (fr)	2004-09-09	2006-12-01	Sanofi Aventis Sa	Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh)	2004-12-23	2013-08-01	Merck Sharp & Dohme	包含生物素殘基之抗血栓雙重抑制劑
GB0507577D0 (en)	2005-04-14	2005-05-18	Novartis Ag	Organic compounds
IL188647A0 (en)	2008-01-08	2008-11-03	Orina Gribova	Adaptable structured drug and supplements administration system (for oral and/or transdermal applications)
WO2009130704A1 (en) *	2008-04-24	2009-10-29	Technion Research And Development Foundation Ltd.	Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds
KR101529061B1 (ko)	2008-05-30	2015-06-16	모멘타 파머슈티컬스 인코포레이티드	당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
FR2935386B1 (fr) *	2008-08-26	2010-09-10	Sanofi Aventis	Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
WO2010117803A2 (en) *	2009-03-30	2010-10-14	University Of Georgia Research Foundation, Inc.	Heparan sulfate synthesis
EP2451442A4 (en)	2009-07-09	2014-02-12	Oshadi Drug Administration Ltd	MATRIX COMPOSITION COMPOSITIONS, METHODS AND USES
US8288515B2 (en)	2009-07-31	2012-10-16	Reliable Biopharmaceutical Corporation	Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof
FR2949114B1 (fr)	2009-08-14	2011-08-26	Sanofi Aventis	OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949115B1 (fr)	2009-08-14	2012-11-02	Sanofi Aventis	OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en)	2009-10-30	2013-04-16	Reliable Biopharmaceutical Corporation	Efficient and scalable process for the manufacture of Fondaparinux sodium
EP2614089A1 (fr)	2010-09-10	2013-07-17	Sanofi-Aventis	Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
US9005664B2 (en)	2010-10-17	2015-04-14	Technion Research And Development Foundation Ltd.	Denatured lactoglobulin and polyphenol coassemblies
FR2970969B1 (fr)	2011-01-27	2013-10-18	Sanofi Aventis	Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ260933A (en) *	1993-07-16	1996-07-26	Hercules Inc	Cation-complexed polysaccharides; use in foods and pharmaceuticals
FR2749849B1 (fr) *	1996-06-14	1998-09-04	Sanofi Sa	Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
CZ427499A3 (cs) *	1998-05-29	2000-05-17	The Procter & Gamble Company	Jemné topické antimikrobiální přípravky

1998
- 1998-01-19 FR FR9800515A patent/FR2773804B1/fr not_active Expired - Lifetime
1999
- 1999-01-13 JP JP2000540158A patent/JP4402835B2/ja not_active Expired - Fee Related
- 1999-01-13 KR KR10-2000-7007824A patent/KR100513196B1/ko not_active IP Right Cessation
- 1999-01-13 AU AU19745/99A patent/AU741748B2/en not_active Ceased
- 1999-01-13 BR BRPI9907025A patent/BRPI9907025B8/pt not_active IP Right Cessation
- 1999-01-13 CA CA002317465A patent/CA2317465C/en not_active Expired - Fee Related
- 1999-01-13 EP EP99900524A patent/EP1049721B1/fr not_active Expired - Lifetime
- 1999-01-13 IL IL13724199A patent/IL137241A0/xx not_active IP Right Cessation
- 1999-01-13 RU RU2000119753/04A patent/RU2211224C2/ru not_active IP Right Cessation
- 1999-01-13 DE DE69900718T patent/DE69900718T2/de not_active Expired - Lifetime
- 1999-01-13 NZ NZ505492A patent/NZ505492A/en not_active IP Right Cessation
- 1999-01-13 SI SI9930025T patent/SI1049721T1/xx unknown
- 1999-01-13 DK DK99900524T patent/DK1049721T3/da active
- 1999-01-13 WO PCT/FR1999/000044 patent/WO1999036443A1/fr active IP Right Grant
- 1999-01-13 PT PT99900524T patent/PT1049721E/pt unknown
- 1999-01-13 CN CNB998022438A patent/CN1165550C/zh not_active Expired - Fee Related
- 1999-01-13 UA UA2000074011A patent/UA60352C2/uk unknown
- 1999-01-13 HU HU0102009A patent/HU228333B1/hu not_active IP Right Cessation
- 1999-01-13 ES ES99900524T patent/ES2168000T3/es not_active Expired - Lifetime
- 1999-01-13 AT AT99900524T patent/ATE209219T1/de active
- 1999-01-13 CZ CZ20002635A patent/CZ297815B6/cs not_active IP Right Cessation
- 1999-01-13 SK SK1078-2000A patent/SK283411B6/sk not_active IP Right Cessation
- 1999-01-13 EE EEP200000429A patent/EE04157B1/xx unknown
- 1999-01-13 TR TR2000/02078T patent/TR200002078T2/xx unknown
- 1999-01-13 US US09/600,506 patent/US6528497B1/en not_active Expired - Lifetime
- 1999-01-13 PL PL341875A patent/PL202802B1/pl unknown
- 1999-01-14 GT GT199900003A patent/GT199900003A/es unknown
- 1999-01-15 MA MA25431A patent/MA26597A1/fr unknown
- 1999-01-16 EG EG5499A patent/EG23982A/xx active
- 1999-01-16 DZ DZ990010A patent/DZ2709A1/xx active
- 1999-01-18 UY UY25356A patent/UY25356A1/es not_active Application Discontinuation
- 1999-01-18 MY MYPI99000203A patent/MY119090A/en unknown
- 1999-01-18 AR ARP990100172A patent/AR013019A1/es active IP Right Grant
- 1999-01-18 TW TW088100716A patent/TW548279B/zh not_active IP Right Cessation
- 1999-01-19 PE PE1999000044A patent/PE20000269A1/es not_active Application Discontinuation
- 1999-01-19 CO CO99002526A patent/CO4970795A1/es unknown
- 1999-01-19 ZA ZA9900355A patent/ZA99355B/xx unknown
- 1999-02-27 SA SA99191113A patent/SA99191113B1/ar unknown
2000
- 2000-07-17 NO NO20003662A patent/NO329903B1/no not_active IP Right Cessation
- 2000-07-19 HR HR970630A patent/HRP20000480B1/xx not_active IP Right Cessation
2001
- 2001-02-12 HK HK01101003A patent/HK1030002A1/xx not_active IP Right Cessation

Also Published As

Publication number	Publication date
DZ2709A1 (fr)	2003-09-01
ES2168000T3 (es)	2002-05-16
BR9907025B1 (pt)	2013-12-10
NZ505492A (en)	2001-12-21
DE69900718T2 (de)	2002-08-22
FR2773804A1 (fr)	1999-07-23
CN1288470A (zh)	2001-03-21
ATE209219T1 (de)	2001-12-15
ZA99355B (en)	2000-10-11
DK1049721T3 (da)	2002-04-02
TR200002078T2 (tr)	2000-11-21
EE200000429A1 (et)	2003-06-16
PL341875A1 (en)	2001-05-07
CZ20002635A3 (cs)	2000-12-13
EE04157B1 (et)	2003-10-15
SA99191113B1 (ar)	2006-10-11
AR013019A1 (es)	2000-11-22
BR9907025A (pt)	2000-10-17
NO20003662D0 (no)	2000-07-17
PL202802B1 (pl)	2009-07-31
EP1049721B1 (fr)	2001-11-21
CZ297815B6 (cs)	2007-04-04
EP1049721A1 (fr)	2000-11-08
HK1030002A1 (en)	2001-04-20
HRP20000480A2 (en)	2000-12-31
CA2317465C (en)	2008-05-20
NO20003662L (no)	2000-09-14
AU1974599A (en)	1999-08-02
PT1049721E (pt)	2002-05-31
US6528497B1 (en)	2003-03-04
TW548279B (en)	2003-08-21
EE200000429A (et)	2001-12-17
KR20010034189A (ko)	2001-04-25
IL137241A0 (en)	2001-07-24
SI1049721T1 (en)	2002-06-30
EG23982A (en)	2008-02-27
RU2211224C2 (ru)	2003-08-27
WO1999036443A1 (fr)	1999-07-22
UY25356A1 (es)	2000-10-31
NO329903B1 (no)	2011-01-24
PE20000269A1 (es)	2000-06-15
CA2317465A1 (en)	1999-07-22
GT199900003A (es)	2000-07-07
CO4970795A1 (es)	2000-11-07
DE69900718D1 (de)	2002-02-21
FR2773804B1 (fr)	2000-02-18
KR100513196B1 (ko)	2005-09-07
HU228333B1 (en)	2013-03-28
JP4402835B2 (ja)	2010-01-20
MA26597A1 (fr)	2004-12-20
SK10782000A3 (sk)	2001-02-12
SK283411B6 (sk)	2003-07-01
CN1165550C (zh)	2004-09-08
UA60352C2 (uk)	2003-10-15
MY119090A (en)	2005-03-31
HUP0102009A3 (en)	2003-07-28
AU741748B2 (en)	2001-12-06
JP2002509164A (ja)	2002-03-26
BRPI9907025B8 (pt)	2016-09-13
HUP0102009A1 (hu)	2001-11-28

Legal Events

Date	Code	Title	Description
2000-12-31	A1OB	Publication of a patent application
2001-01-16	ARAI	Request for the grant of a patent on the basis of the submitted results of a substantive examination of a patent application
2002-04-30	B1PR	Patent granted
2004-04-20	PPPP	Transfer of rights	Owner name: SANOFI-SYNTHELABO, FR
2005-02-18	PNAN	Change of the applicant name, address/residence	Owner name: SANOFI-AVENTIS, FR
2016-12-14	ODRP	Renewal fee for the maintenance of a patent	Payment date: 20161214 Year of fee payment: 19
2018-07-25	PBON	Lapse due to non-payment of renewal fee	Effective date: 20180113

Publication	Publication Date	Title
PL380081A1 (pl)	2002-04-22	Pochodne 3,3-difenylopropyloamin, sposoby ich wytwarzania, kompozycja farmaceutyczna oraz zastosowania
HUP0200312A3 (en)	2002-12-28	Substituted 2-phenylbenzimidazoles, pharmaceutical compositions containing them, the production thereof and their use
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HRP20000480B1 (en)	2002-04-30	Synthetic polysaccharides, their method of production and pharmaceutical compositions containing the same
HUP9902287A3 (en)	2001-09-28	Synthetic polysaccharides, preparation method therefor and pharmaceutical compositions containing same
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HUP0004588A3 (en)	2002-10-28	Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocine-10-oles, method for the production and use thereof as medicaments and pharmaceutical compositions containing them
PL347096A1 (en)	2002-03-25	Substituted 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)-propanol derivatives, methods for their production, pharmaceutical compositions containing the same and their use
HUP0103316A3 (en)	2002-06-28	2-ureido-pyrimidone derivatives, method for producing them, pharmaceutical compositions containing them and their use
IL139531A0 (en)	2001-11-25	Human antithrombin iii, methods for the production thereof and pharmaceutical compositions containing the same
EP1059304A4 (en)	2003-01-22	NOVEL POLYSACCHARIDE DERIVATIVES, PROCESS FOR PRODUCING THE SAME, AND MEDICINAL COMPOSITIONS CONTAINING THESE NEW DERIVATIVES AS ACTIVE INGREDIENT
HUP9700954A3 (en)	1998-04-28	Substituted 1-naphtoylguanidine derivatives, their production, and pharmaceutical compositions containing them
HUP9700437A3 (en)	2000-03-28	Guanidino-derivatives of substituted thienyl-alkenyl-carboxylic-acids, their production, and pharmaceutical compositions containing them
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