FR2935386B1 - Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine - Google Patents

Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine

Info

Publication number
FR2935386B1
FR2935386B1 FR0804704A FR0804704A FR2935386B1 FR 2935386 B1 FR2935386 B1 FR 2935386B1 FR 0804704 A FR0804704 A FR 0804704A FR 0804704 A FR0804704 A FR 0804704A FR 2935386 B1 FR2935386 B1 FR 2935386B1
Authority
FR
France
Prior art keywords
liaison
covalent
antithrombotic activity
amino chain
novel polysaccharides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0804704A
Other languages
English (en)
Other versions
FR2935386A1 (fr
Inventor
Joseph Michael Schofield
Dave Smith
Patrick Soubayrol
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Sanofi Aventis France
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis France filed Critical Sanofi Aventis France
Priority to FR0804704A priority Critical patent/FR2935386B1/fr
Priority to JP2011524423A priority patent/JP2012500884A/ja
Priority to US13/060,810 priority patent/US8492352B2/en
Priority to PCT/FR2009/001023 priority patent/WO2010023374A1/fr
Priority to EP09737025A priority patent/EP2328935A1/fr
Publication of FR2935386A1 publication Critical patent/FR2935386A1/fr
Application granted granted Critical
Publication of FR2935386B1 publication Critical patent/FR2935386B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FR0804704A 2008-08-26 2008-08-26 Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine Expired - Fee Related FR2935386B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR0804704A FR2935386B1 (fr) 2008-08-26 2008-08-26 Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
JP2011524423A JP2012500884A (ja) 2008-08-26 2009-08-24 共有結合およびアミノ鎖を含む、抗血栓活性を有する多糖類
US13/060,810 US8492352B2 (en) 2008-08-26 2009-08-24 Polysaccharides with antithrombotic activity, including a covalent bond and an amino chain
PCT/FR2009/001023 WO2010023374A1 (fr) 2008-08-26 2009-08-24 Polysaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine
EP09737025A EP2328935A1 (fr) 2008-08-26 2009-08-24 Polysaccharides a activite antithrombotique comprenant une liaison covalente avec une chaine amine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0804704A FR2935386B1 (fr) 2008-08-26 2008-08-26 Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine

Publications (2)

Publication Number Publication Date
FR2935386A1 FR2935386A1 (fr) 2010-03-05
FR2935386B1 true FR2935386B1 (fr) 2010-09-10

Family

ID=40521663

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0804704A Expired - Fee Related FR2935386B1 (fr) 2008-08-26 2008-08-26 Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine

Country Status (5)

Country Link
US (1) US8492352B2 (fr)
EP (1) EP2328935A1 (fr)
JP (1) JP2012500884A (fr)
FR (1) FR2935386B1 (fr)
WO (1) WO2010023374A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013537181A (ja) 2010-09-10 2013-09-30 サノフイ 抗血栓活性及び改善された代謝安定性を有するビオチン化多糖類
JPWO2018043667A1 (ja) 2016-08-31 2018-08-30 王子ホールディングス株式会社 酸性キシロオリゴ糖の製造方法及び酸性キシロオリゴ糖
JP6225321B1 (ja) 2016-08-31 2017-11-08 王子ホールディングス株式会社 ポリ硫酸ペントサンの製造方法
JP6281659B1 (ja) 2017-02-28 2018-02-21 王子ホールディングス株式会社 ポリ硫酸ペントサン、医薬組成物及び抗凝固剤
CA3065747A1 (fr) 2017-05-31 2018-12-06 Oji Holdings Corporation Composition hydratante comprenant un polysulfate de pentosanne
KR20200051688A (ko) * 2017-09-12 2020-05-13 오지 홀딩스 가부시키가이샤 폴리황산펜토산 및 폴리황산펜토산의 제조 방법
PT3730521T (pt) 2017-12-20 2023-06-19 Oji Holdings Corp Polissulfato de pentosano e medicamento contendo polissulfato de pentosano
CN112717207A (zh) * 2020-12-15 2021-04-30 山东大学 一种基于仿生多巴胺的长效抗菌多功能涂层及其制备方法和应用
CN113616861A (zh) * 2021-08-03 2021-11-09 广州维力医疗器械股份有限公司 逐层自组装复合抗凝血涂层、其制备方法及医疗器械

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2751334B1 (fr) * 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2773804B1 (fr) * 1998-01-19 2000-02-18 Sanofi Sa Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine

Also Published As

Publication number Publication date
US20110306567A1 (en) 2011-12-15
FR2935386A1 (fr) 2010-03-05
US8492352B2 (en) 2013-07-23
WO2010023374A1 (fr) 2010-03-04
JP2012500884A (ja) 2012-01-12
EP2328935A1 (fr) 2011-06-08

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Effective date: 20150430