TR200002078T2 - Sentetik polisakkaridler, hazırlanmaları için proses ve bunları içeren farmasötik kompozisyonlar. - Google Patents

Sentetik polisakkaridler, hazırlanmaları için proses ve bunları içeren farmasötik kompozisyonlar.

Info

Publication number
TR200002078T2
TR200002078T2 TR2000/02078T TR200002078T TR200002078T2 TR 200002078 T2 TR200002078 T2 TR 200002078T2 TR 2000/02078 T TR2000/02078 T TR 2000/02078T TR 200002078 T TR200002078 T TR 200002078T TR 200002078 T2 TR200002078 T2 TR 200002078T2
Authority
TR
Turkey
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
synthetic polysaccharides
polysaccharides
Prior art date
Application number
TR2000/02078T
Other languages
English (en)
Inventor
Basten Johannes
Dreef-Tromp Cornelia
Driguez Pierre-Alexandre
Duchaussoy Philippe
Herbert Jean-Marc
Petitou Maurice
Van Boeckel Constant
Original Assignee
Sanofi-Synthelabo
Akzo Nobel N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo, Akzo Nobel N.V. filed Critical Sanofi-Synthelabo
Publication of TR200002078T2 publication Critical patent/TR200002078T2/tr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)

Abstract

Mevcut bulus asidik formdaki sentetik polisakkarid ve bunun farmasötik olarak kabul edilebilen tuzlari olup, bahsedilen polisakkaridin anyonik formu istem 1'de tanimlanan formül (I) ila (V)'ten birine karsilik gelmektedir. Bahsedilen polisakkaridler koagulasyon düzensizliklerine bagli hastaliklarin tedavisinde kullanilabilmektedir.
TR2000/02078T 1998-01-19 1999-01-13 Sentetik polisakkaridler, hazırlanmaları için proses ve bunları içeren farmasötik kompozisyonlar. TR200002078T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9800515A FR2773804B1 (fr) 1998-01-19 1998-01-19 Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant

Publications (1)

Publication Number Publication Date
TR200002078T2 true TR200002078T2 (tr) 2000-11-21

Family

ID=9521914

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/02078T TR200002078T2 (tr) 1998-01-19 1999-01-13 Sentetik polisakkaridler, hazırlanmaları için proses ve bunları içeren farmasötik kompozisyonlar.

Country Status (41)

Country Link
US (1) US6528497B1 (tr)
EP (1) EP1049721B1 (tr)
JP (1) JP4402835B2 (tr)
KR (1) KR100513196B1 (tr)
CN (1) CN1165550C (tr)
AR (1) AR013019A1 (tr)
AT (1) ATE209219T1 (tr)
AU (1) AU741748B2 (tr)
BR (1) BRPI9907025B8 (tr)
CA (1) CA2317465C (tr)
CO (1) CO4970795A1 (tr)
CZ (1) CZ297815B6 (tr)
DE (1) DE69900718T2 (tr)
DK (1) DK1049721T3 (tr)
DZ (1) DZ2709A1 (tr)
EE (1) EE04157B1 (tr)
EG (1) EG23982A (tr)
ES (1) ES2168000T3 (tr)
FR (1) FR2773804B1 (tr)
GT (1) GT199900003A (tr)
HK (1) HK1030002A1 (tr)
HR (1) HRP20000480B1 (tr)
HU (1) HU228333B1 (tr)
IL (1) IL137241A0 (tr)
MA (1) MA26597A1 (tr)
MY (1) MY119090A (tr)
NO (1) NO329903B1 (tr)
NZ (1) NZ505492A (tr)
PE (1) PE20000269A1 (tr)
PL (1) PL202802B1 (tr)
PT (1) PT1049721E (tr)
RU (1) RU2211224C2 (tr)
SA (1) SA99191113B1 (tr)
SI (1) SI1049721T1 (tr)
SK (1) SK283411B6 (tr)
TR (1) TR200002078T2 (tr)
TW (1) TW548279B (tr)
UA (1) UA60352C2 (tr)
UY (1) UY25356A1 (tr)
WO (1) WO1999036443A1 (tr)
ZA (1) ZA99355B (tr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
IL188647A0 (en) 2008-01-08 2008-11-03 Orina Gribova Adaptable structured drug and supplements administration system (for oral and/or transdermal applications)
WO2009130704A1 (en) * 2008-04-24 2009-10-29 Technion Research And Development Foundation Ltd. Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds
KR101529061B1 (ko) 2008-05-30 2015-06-16 모멘타 파머슈티컬스 인코포레이티드 당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
FR2935386B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
WO2010117803A2 (en) * 2009-03-30 2010-10-14 University Of Georgia Research Foundation, Inc. Heparan sulfate synthesis
EP2451442A4 (en) 2009-07-09 2014-02-12 Oshadi Drug Administration Ltd MATRIX COMPOSITION COMPOSITIONS, METHODS AND USES
US8288515B2 (en) 2009-07-31 2012-10-16 Reliable Biopharmaceutical Corporation Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
EP2614089A1 (fr) 2010-09-10 2013-07-17 Sanofi-Aventis Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
US9005664B2 (en) 2010-10-17 2015-04-14 Technion Research And Development Foundation Ltd. Denatured lactoglobulin and polyphenol coassemblies
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ260933A (en) * 1993-07-16 1996-07-26 Hercules Inc Cation-complexed polysaccharides; use in foods and pharmaceuticals
FR2749849B1 (fr) * 1996-06-14 1998-09-04 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
CZ427499A3 (cs) * 1998-05-29 2000-05-17 The Procter & Gamble Company Jemné topické antimikrobiální přípravky

Also Published As

Publication number Publication date
DZ2709A1 (fr) 2003-09-01
ES2168000T3 (es) 2002-05-16
BR9907025B1 (pt) 2013-12-10
NZ505492A (en) 2001-12-21
DE69900718T2 (de) 2002-08-22
FR2773804A1 (fr) 1999-07-23
CN1288470A (zh) 2001-03-21
ATE209219T1 (de) 2001-12-15
ZA99355B (en) 2000-10-11
DK1049721T3 (da) 2002-04-02
EE200000429A1 (et) 2003-06-16
PL341875A1 (en) 2001-05-07
CZ20002635A3 (cs) 2000-12-13
EE04157B1 (et) 2003-10-15
SA99191113B1 (ar) 2006-10-11
AR013019A1 (es) 2000-11-22
BR9907025A (pt) 2000-10-17
NO20003662D0 (no) 2000-07-17
PL202802B1 (pl) 2009-07-31
EP1049721B1 (fr) 2001-11-21
CZ297815B6 (cs) 2007-04-04
EP1049721A1 (fr) 2000-11-08
HK1030002A1 (en) 2001-04-20
HRP20000480A2 (en) 2000-12-31
CA2317465C (en) 2008-05-20
NO20003662L (no) 2000-09-14
AU1974599A (en) 1999-08-02
PT1049721E (pt) 2002-05-31
US6528497B1 (en) 2003-03-04
TW548279B (en) 2003-08-21
EE200000429A (et) 2001-12-17
KR20010034189A (ko) 2001-04-25
IL137241A0 (en) 2001-07-24
SI1049721T1 (en) 2002-06-30
EG23982A (en) 2008-02-27
RU2211224C2 (ru) 2003-08-27
WO1999036443A1 (fr) 1999-07-22
UY25356A1 (es) 2000-10-31
NO329903B1 (no) 2011-01-24
PE20000269A1 (es) 2000-06-15
CA2317465A1 (en) 1999-07-22
GT199900003A (es) 2000-07-07
CO4970795A1 (es) 2000-11-07
DE69900718D1 (de) 2002-02-21
FR2773804B1 (fr) 2000-02-18
KR100513196B1 (ko) 2005-09-07
HRP20000480B1 (en) 2002-04-30
HU228333B1 (en) 2013-03-28
JP4402835B2 (ja) 2010-01-20
MA26597A1 (fr) 2004-12-20
SK10782000A3 (sk) 2001-02-12
SK283411B6 (sk) 2003-07-01
CN1165550C (zh) 2004-09-08
UA60352C2 (uk) 2003-10-15
MY119090A (en) 2005-03-31
HUP0102009A3 (en) 2003-07-28
AU741748B2 (en) 2001-12-06
JP2002509164A (ja) 2002-03-26
BRPI9907025B8 (pt) 2016-09-13
HUP0102009A1 (hu) 2001-11-28

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