CO4970795A1 - Polisacaridos de sintesis, procedimiento para su preparacion y composiciones farmaceuticas que los contienen - Google Patents

Polisacaridos de sintesis, procedimiento para su preparacion y composiciones farmaceuticas que los contienen

Info

Publication number
CO4970795A1
CO4970795A1 CO99002526A CO99002526A CO4970795A1 CO 4970795 A1 CO4970795 A1 CO 4970795A1 CO 99002526 A CO99002526 A CO 99002526A CO 99002526 A CO99002526 A CO 99002526A CO 4970795 A1 CO4970795 A1 CO 4970795A1
Authority
CO
Colombia
Prior art keywords
polysaccharides
synthesis
procedure
contain
preparation
Prior art date
Application number
CO99002526A
Other languages
English (en)
Inventor
Basten Johannes
Cornelia Dreef-Tromp
Alexandre Driguez Pierre
Philippe Duchaussoy
Herbert Jean Marc
Maurice Petitou
Boeckel Constant Van
Original Assignee
Akzo Nobel Nv
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv, Sanofi Synthelabo filed Critical Akzo Nobel Nv
Publication of CO4970795A1 publication Critical patent/CO4970795A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)

Abstract

Polisacárido de síntesis en forma de ácido y sus salesfarmacéuticamente aceptables, cuya forma aniónica responde a alguna de las fórmulas (I) a (V) siguientes:Polisacárido conforme con la reivindicación 1, en forma de sal de sodio o de potasio.
CO99002526A 1998-01-19 1999-01-19 Polisacaridos de sintesis, procedimiento para su preparacion y composiciones farmaceuticas que los contienen CO4970795A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9800515A FR2773804B1 (fr) 1998-01-19 1998-01-19 Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant

Publications (1)

Publication Number Publication Date
CO4970795A1 true CO4970795A1 (es) 2000-11-07

Family

ID=9521914

Family Applications (1)

Application Number Title Priority Date Filing Date
CO99002526A CO4970795A1 (es) 1998-01-19 1999-01-19 Polisacaridos de sintesis, procedimiento para su preparacion y composiciones farmaceuticas que los contienen

Country Status (41)

Country Link
US (1) US6528497B1 (es)
EP (1) EP1049721B1 (es)
JP (1) JP4402835B2 (es)
KR (1) KR100513196B1 (es)
CN (1) CN1165550C (es)
AR (1) AR013019A1 (es)
AT (1) ATE209219T1 (es)
AU (1) AU741748B2 (es)
BR (1) BRPI9907025B8 (es)
CA (1) CA2317465C (es)
CO (1) CO4970795A1 (es)
CZ (1) CZ297815B6 (es)
DE (1) DE69900718T2 (es)
DK (1) DK1049721T3 (es)
DZ (1) DZ2709A1 (es)
EE (1) EE04157B1 (es)
EG (1) EG23982A (es)
ES (1) ES2168000T3 (es)
FR (1) FR2773804B1 (es)
GT (1) GT199900003A (es)
HK (1) HK1030002A1 (es)
HR (1) HRP20000480B1 (es)
HU (1) HU228333B1 (es)
IL (1) IL137241A0 (es)
MA (1) MA26597A1 (es)
MY (1) MY119090A (es)
NO (1) NO329903B1 (es)
NZ (1) NZ505492A (es)
PE (1) PE20000269A1 (es)
PL (1) PL202802B1 (es)
PT (1) PT1049721E (es)
RU (1) RU2211224C2 (es)
SA (1) SA99191113B1 (es)
SI (1) SI1049721T1 (es)
SK (1) SK283411B6 (es)
TR (1) TR200002078T2 (es)
TW (1) TW548279B (es)
UA (1) UA60352C2 (es)
UY (1) UY25356A1 (es)
WO (1) WO1999036443A1 (es)
ZA (1) ZA99355B (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
IL188647A0 (en) 2008-01-08 2008-11-03 Orina Gribova Adaptable structured drug and supplements administration system (for oral and/or transdermal applications)
WO2009130704A1 (en) * 2008-04-24 2009-10-29 Technion Research And Development Foundation Ltd. Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds
KR101529061B1 (ko) 2008-05-30 2015-06-16 모멘타 파머슈티컬스 인코포레이티드 당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
FR2935386B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
WO2010117803A2 (en) * 2009-03-30 2010-10-14 University Of Georgia Research Foundation, Inc. Heparan sulfate synthesis
EP2451442A4 (en) 2009-07-09 2014-02-12 Oshadi Drug Administration Ltd MATRIX COMPOSITION COMPOSITIONS, METHODS AND USES
US8288515B2 (en) 2009-07-31 2012-10-16 Reliable Biopharmaceutical Corporation Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
EP2614089A1 (fr) 2010-09-10 2013-07-17 Sanofi-Aventis Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
US9005664B2 (en) 2010-10-17 2015-04-14 Technion Research And Development Foundation Ltd. Denatured lactoglobulin and polyphenol coassemblies
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ260933A (en) * 1993-07-16 1996-07-26 Hercules Inc Cation-complexed polysaccharides; use in foods and pharmaceuticals
FR2749849B1 (fr) * 1996-06-14 1998-09-04 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
CZ427499A3 (cs) * 1998-05-29 2000-05-17 The Procter & Gamble Company Jemné topické antimikrobiální přípravky

Also Published As

Publication number Publication date
DZ2709A1 (fr) 2003-09-01
ES2168000T3 (es) 2002-05-16
BR9907025B1 (pt) 2013-12-10
NZ505492A (en) 2001-12-21
DE69900718T2 (de) 2002-08-22
FR2773804A1 (fr) 1999-07-23
CN1288470A (zh) 2001-03-21
ATE209219T1 (de) 2001-12-15
ZA99355B (en) 2000-10-11
DK1049721T3 (da) 2002-04-02
TR200002078T2 (tr) 2000-11-21
EE200000429A1 (et) 2003-06-16
PL341875A1 (en) 2001-05-07
CZ20002635A3 (cs) 2000-12-13
EE04157B1 (et) 2003-10-15
SA99191113B1 (ar) 2006-10-11
AR013019A1 (es) 2000-11-22
BR9907025A (pt) 2000-10-17
NO20003662D0 (no) 2000-07-17
PL202802B1 (pl) 2009-07-31
EP1049721B1 (fr) 2001-11-21
CZ297815B6 (cs) 2007-04-04
EP1049721A1 (fr) 2000-11-08
HK1030002A1 (en) 2001-04-20
HRP20000480A2 (en) 2000-12-31
CA2317465C (en) 2008-05-20
NO20003662L (no) 2000-09-14
AU1974599A (en) 1999-08-02
PT1049721E (pt) 2002-05-31
US6528497B1 (en) 2003-03-04
TW548279B (en) 2003-08-21
EE200000429A (et) 2001-12-17
KR20010034189A (ko) 2001-04-25
IL137241A0 (en) 2001-07-24
SI1049721T1 (en) 2002-06-30
EG23982A (en) 2008-02-27
RU2211224C2 (ru) 2003-08-27
WO1999036443A1 (fr) 1999-07-22
UY25356A1 (es) 2000-10-31
NO329903B1 (no) 2011-01-24
PE20000269A1 (es) 2000-06-15
CA2317465A1 (en) 1999-07-22
GT199900003A (es) 2000-07-07
DE69900718D1 (de) 2002-02-21
FR2773804B1 (fr) 2000-02-18
KR100513196B1 (ko) 2005-09-07
HRP20000480B1 (en) 2002-04-30
HU228333B1 (en) 2013-03-28
JP4402835B2 (ja) 2010-01-20
MA26597A1 (fr) 2004-12-20
SK10782000A3 (sk) 2001-02-12
SK283411B6 (sk) 2003-07-01
CN1165550C (zh) 2004-09-08
UA60352C2 (uk) 2003-10-15
MY119090A (en) 2005-03-31
HUP0102009A3 (en) 2003-07-28
AU741748B2 (en) 2001-12-06
JP2002509164A (ja) 2002-03-26
BRPI9907025B8 (pt) 2016-09-13
HUP0102009A1 (hu) 2001-11-28

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