DK1049721T3 - Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske præparater indeholdende disse - Google Patents

Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske præparater indeholdende disse

Info

Publication number
DK1049721T3
DK1049721T3 DK99900524T DK99900524T DK1049721T3 DK 1049721 T3 DK1049721 T3 DK 1049721T3 DK 99900524 T DK99900524 T DK 99900524T DK 99900524 T DK99900524 T DK 99900524T DK 1049721 T3 DK1049721 T3 DK 1049721T3
Authority
DK
Denmark
Prior art keywords
processes
preparation
pharmaceutical compositions
compositions containing
synthetic polysaccharides
Prior art date
Application number
DK99900524T
Other languages
Danish (da)
English (en)
Inventor
Johannes Basten
Cornelia Dreef-Tromp
Pierre-Alexandre Driguez
Philippe Duchaussoy
Jean-Marc Herbert
Maurice Petitou
Boeckel Constant Van
Original Assignee
Akzo Nobel Nv
Sanofi Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv, Sanofi Synthelabo filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of DK1049721T3 publication Critical patent/DK1049721T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
DK99900524T 1998-01-19 1999-01-13 Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske præparater indeholdende disse DK1049721T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9800515A FR2773804B1 (fr) 1998-01-19 1998-01-19 Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant
PCT/FR1999/000044 WO1999036443A1 (fr) 1998-01-19 1999-01-13 Polysaccharides de synthese, procede pour leur preparation et compositions pharmaceutiques le contenant

Publications (1)

Publication Number Publication Date
DK1049721T3 true DK1049721T3 (da) 2002-04-02

Family

ID=9521914

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99900524T DK1049721T3 (da) 1998-01-19 1999-01-13 Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske præparater indeholdende disse

Country Status (41)

Country Link
US (1) US6528497B1 (no)
EP (1) EP1049721B1 (no)
JP (1) JP4402835B2 (no)
KR (1) KR100513196B1 (no)
CN (1) CN1165550C (no)
AR (1) AR013019A1 (no)
AT (1) ATE209219T1 (no)
AU (1) AU741748B2 (no)
BR (1) BRPI9907025B8 (no)
CA (1) CA2317465C (no)
CO (1) CO4970795A1 (no)
CZ (1) CZ297815B6 (no)
DE (1) DE69900718T2 (no)
DK (1) DK1049721T3 (no)
DZ (1) DZ2709A1 (no)
EE (1) EE04157B1 (no)
EG (1) EG23982A (no)
ES (1) ES2168000T3 (no)
FR (1) FR2773804B1 (no)
GT (1) GT199900003A (no)
HK (1) HK1030002A1 (no)
HR (1) HRP20000480B1 (no)
HU (1) HU228333B1 (no)
IL (1) IL137241A0 (no)
MA (1) MA26597A1 (no)
MY (1) MY119090A (no)
NO (1) NO329903B1 (no)
NZ (1) NZ505492A (no)
PE (1) PE20000269A1 (no)
PL (1) PL202802B1 (no)
PT (1) PT1049721E (no)
RU (1) RU2211224C2 (no)
SA (1) SA99191113B1 (no)
SI (1) SI1049721T1 (no)
SK (1) SK283411B6 (no)
TR (1) TR200002078T2 (no)
TW (1) TW548279B (no)
UA (1) UA60352C2 (no)
UY (1) UY25356A1 (no)
WO (1) WO1999036443A1 (no)
ZA (1) ZA99355B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
GB0507577D0 (en) 2005-04-14 2005-05-18 Novartis Ag Organic compounds
IL188647A0 (en) 2008-01-08 2008-11-03 Orina Gribova Adaptable structured drug and supplements administration system (for oral and/or transdermal applications)
WO2009130704A1 (en) * 2008-04-24 2009-10-29 Technion Research And Development Foundation Ltd. Beta-lactoglobulin-polysaccharide nanoparticles for hydrophobic bioactive compounds
KR101529061B1 (ko) 2008-05-30 2015-06-16 모멘타 파머슈티컬스 인코포레이티드 당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
FR2935386B1 (fr) * 2008-08-26 2010-09-10 Sanofi Aventis Nouveaux polysaccharides a activite antithrombotique comprenant une liaion covalente avec une chaine amine
WO2010117803A2 (en) * 2009-03-30 2010-10-14 University Of Georgia Research Foundation, Inc. Heparan sulfate synthesis
EP2451442A4 (en) 2009-07-09 2014-02-12 Oshadi Drug Administration Ltd MATRIX COMPOSITION COMPOSITIONS, METHODS AND USES
US8288515B2 (en) 2009-07-31 2012-10-16 Reliable Biopharmaceutical Corporation Process for preparing Fondaparinux sodium and intermediates useful in the synthesis thereof
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
EP2614089A1 (fr) 2010-09-10 2013-07-17 Sanofi-Aventis Polysaccharides biotinyles a activite antithrombotique et presentant une stabilite metabolique amelioree
US9005664B2 (en) 2010-10-17 2015-04-14 Technion Research And Development Foundation Ltd. Denatured lactoglobulin and polyphenol coassemblies
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ260933A (en) * 1993-07-16 1996-07-26 Hercules Inc Cation-complexed polysaccharides; use in foods and pharmaceuticals
FR2749849B1 (fr) * 1996-06-14 1998-09-04 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
CZ427499A3 (cs) * 1998-05-29 2000-05-17 The Procter & Gamble Company Jemné topické antimikrobiální přípravky

Also Published As

Publication number Publication date
DZ2709A1 (fr) 2003-09-01
ES2168000T3 (es) 2002-05-16
BR9907025B1 (pt) 2013-12-10
NZ505492A (en) 2001-12-21
DE69900718T2 (de) 2002-08-22
FR2773804A1 (fr) 1999-07-23
CN1288470A (zh) 2001-03-21
ATE209219T1 (de) 2001-12-15
ZA99355B (en) 2000-10-11
TR200002078T2 (tr) 2000-11-21
EE200000429A1 (et) 2003-06-16
PL341875A1 (en) 2001-05-07
CZ20002635A3 (cs) 2000-12-13
EE04157B1 (et) 2003-10-15
SA99191113B1 (ar) 2006-10-11
AR013019A1 (es) 2000-11-22
BR9907025A (pt) 2000-10-17
NO20003662D0 (no) 2000-07-17
PL202802B1 (pl) 2009-07-31
EP1049721B1 (fr) 2001-11-21
CZ297815B6 (cs) 2007-04-04
EP1049721A1 (fr) 2000-11-08
HK1030002A1 (en) 2001-04-20
HRP20000480A2 (en) 2000-12-31
CA2317465C (en) 2008-05-20
NO20003662L (no) 2000-09-14
AU1974599A (en) 1999-08-02
PT1049721E (pt) 2002-05-31
US6528497B1 (en) 2003-03-04
TW548279B (en) 2003-08-21
EE200000429A (et) 2001-12-17
KR20010034189A (ko) 2001-04-25
IL137241A0 (en) 2001-07-24
SI1049721T1 (en) 2002-06-30
EG23982A (en) 2008-02-27
RU2211224C2 (ru) 2003-08-27
WO1999036443A1 (fr) 1999-07-22
UY25356A1 (es) 2000-10-31
NO329903B1 (no) 2011-01-24
PE20000269A1 (es) 2000-06-15
CA2317465A1 (en) 1999-07-22
GT199900003A (es) 2000-07-07
CO4970795A1 (es) 2000-11-07
DE69900718D1 (de) 2002-02-21
FR2773804B1 (fr) 2000-02-18
KR100513196B1 (ko) 2005-09-07
HRP20000480B1 (en) 2002-04-30
HU228333B1 (en) 2013-03-28
JP4402835B2 (ja) 2010-01-20
MA26597A1 (fr) 2004-12-20
SK10782000A3 (sk) 2001-02-12
SK283411B6 (sk) 2003-07-01
CN1165550C (zh) 2004-09-08
UA60352C2 (uk) 2003-10-15
MY119090A (en) 2005-03-31
HUP0102009A3 (en) 2003-07-28
AU741748B2 (en) 2001-12-06
JP2002509164A (ja) 2002-03-26
BRPI9907025B8 (pt) 2016-09-13
HUP0102009A1 (hu) 2001-11-28

Similar Documents

Publication Publication Date Title
DK1156049T3 (da) Substituerede heterocykliske forbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DK1117645T3 (da) Arylsubstituerede propanolaminderivater, fremgangsmåder til fremstilling deraf, lægemidler indeholdende disse forbindelser og anvendelse deraf
NO20001409L (no) Karboksamidotiazolderivater, fremgangsmÕte for fremstilling derav og farmasøytiske blandinger
NO20012158D0 (no) Substituerte 2-fenylbenzimidazoler, fremgangsmåte til fremstilling og anvendelse derav
DK199900554A (da) Paroxetinsalte, fremgangsmåde til fremstilling deraf, farmaceutiske præparater omfattende disse og anvendelser deraf
IL138280A0 (en) 20-KETO-11β-ARYLSTERIODS, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THE PREPARATION THEREOF
DK1112266T3 (da) Substituerede 4-amino-2-arylpyrimidiner, fremstilling og anvendelse deraf og farmaceutiske præparater indeholdende dem
DK1049721T3 (da) Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske præparater indeholdende disse
HUP0103884A3 (en) Arylsulfonanilide urea-derivatives, pharmaceutical compositions containing them and their use
NO975987D0 (no) 4-Fenylaminotiazol-derivater, fremgangsmåte for fremstilling av disse og farmasöytiske blandinger inneholdende nevnte derivater
DK0885204T3 (da) Nye arylglycinamidderivater, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende disse forbindelser
YU2903A (sh) Smeše heparinskih derivata polisaharida, njihovo dobijanje i farmaceutske smeše koje ih sadrže
IL139529A0 (en) Platinum complexes, processes for the preparation thereof and pharmaceutical compositions containing the same
DK0912613T3 (da) Syntetiske polysaccharider, fremgangsmåde til deres fremstilling og farmaceutiske præparater, der indeholder dem
PL345354A1 (en) 2-aminopyridine erivatives, their use as medicines and pharmaceutical compositions containing them
HUP0102215A3 (en) Benzoylpyridazines, pharmaceutical compositions containing the same and process for their preparation
DK1054672T3 (da) Morfinsulfatmikrogranula, fremgangsmåde til fremstilling deraf og farmaceutiske præparater
NO960272D0 (no) Oksatiolaner, fremgangsmåte for deres fremstilling og farmasöytiske preparater som inneholder de samme
IL139528A0 (en) Platinum complexes, processes for the preparation thereof and pharmaceutical compositions containing the same
DK1171444T3 (da) Pyridothienodiazepiner, fremgangsmåde til fremstilling af disse og farmaceutiske præparater indeholdende disse
IL139531A0 (en) Human antithrombin iii, methods for the production thereof and pharmaceutical compositions containing the same
DK1263719T3 (da) N-deacetylthiocolchin-derivater og farmaceutiske sammensætninger indeholdende disse.
DK1245565T3 (da) Indenoindolon-forbindelse, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende disse
DK1100775T3 (da) 2,5-Substituerede benzensulfonylurinstoffer og -thiourinstoffer, fremgangsmåde til fremstilling deraf, anvendelse deraf og farmaceutiske præparater indeholdende disse
DK1215213T3 (da) Bicylliske aminopyrazinonderivater, fremstilling deraf og farmaceutiske sammensætninger, som indeholder disse