US3709898A
(en)
|
1971-02-09 |
1973-01-09 |
Upjohn Co |
Process for the production of triazolobenzodiazepines and intermediates
|
US3681343A
(en)
|
1971-05-11 |
1972-08-01 |
Upjohn Co |
6-phenyl-s-triazolo{8 4,3-a{9 {8 1,4{9 {0 benzodiazepines
|
US3812259A
(en)
|
1971-08-09 |
1974-05-21 |
Upjohn Co |
Animal feed and process
|
CH622019A5
(en)
|
1975-10-23 |
1981-03-13 |
Upjohn Co |
Process for the preparation of aminotriazolobenzodiazepines
|
FR2329668A1
(fr)
|
1975-10-27 |
1977-05-27 |
Upjohn Co |
Procede de preparation d'aminotriazolobenzodiazepines
|
EP0087850A1
(en)
|
1982-01-04 |
1983-09-07 |
The Upjohn Company |
Benzodiazepines for anti-hypertensive use
|
DE3435973A1
(de)
|
1984-10-01 |
1986-04-10 |
Boehringer Ingelheim KG, 6507 Ingelheim |
Diazepine enthaltende pharmazeutische zusammensetzungen mit paf-antagonistischer wirkung
|
EP0230942B1
(de)
|
1986-01-21 |
1992-04-29 |
Boehringer Ingelheim Kg |
Thieno-1,4-diazepine
|
DE3724164A1
(de)
|
1986-07-25 |
1988-01-28 |
Boehringer Ingelheim Kg |
Neue 1,4-benzodiazepine, ihre herstellung und verwendung
|
WO1988009333A1
(en)
|
1987-05-28 |
1988-12-01 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Thieno(triazolo)diazepine compound and medicinal application of the same
|
JPH0676326B2
(ja)
|
1988-05-24 |
1994-09-28 |
吉富製薬株式会社 |
循環器系疾患治療薬
|
EP0368175A1
(de)
|
1988-11-06 |
1990-05-16 |
Boehringer Ingelheim Kg |
3S,7S-3-(Morpholinocarbonyl)-5-(2-chlorphenyl)-7,10-dimethyl-3,4-dihydro-2H,7H-cyclopenta[4,5]thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin.
|
EP0387613A1
(de)
|
1989-03-03 |
1990-09-19 |
Boehringer Ingelheim Kg |
Neue Thienodiazepine
|
CA2020806A1
(en)
|
1989-07-12 |
1991-01-13 |
Karl-Heinz Weber |
Thienodiazepine derivatives
|
DE4010528A1
(de)
|
1990-04-02 |
1991-10-17 |
Boehringer Ingelheim Kg |
Praeparativ chromatographisches trennverfahren zur herstellung enantiomerenreiner hetrazepine
|
DE4107521A1
(de)
|
1991-03-08 |
1992-09-10 |
Boehringer Ingelheim Kg |
Neue acylaminosubstituierte hetrazepine
|
CA2120939A1
(en)
|
1991-10-11 |
1993-04-15 |
Tetsuya Tahara |
Therapeutic agent for osteoporosis and diazepine compound
|
EP0661284A1
(en)
|
1992-09-18 |
1995-07-05 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Thienodiazepine compound and medicinal use thereof
|
WO1994022872A1
(en)
|
1993-03-30 |
1994-10-13 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Cell adhesion inhibitor and thienotriazolodiazepine compound
|
JP3001979U
(ja)
|
1994-03-14 |
1994-09-06 |
有限会社マルセ木工 |
竿掛け具
|
WO1995032963A1
(fr)
|
1994-06-01 |
1995-12-07 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Compose de thienylazole et compose de thienotriazolodiazepine
|
CA2209424A1
(en)
|
1995-01-06 |
1996-07-11 |
F. Hoffmann-La Roche Ag |
Hydroxymethylimidazodiazepines and their esters
|
US5854238A
(en)
|
1995-09-09 |
1998-12-29 |
Hoffmann-La Roche Inc. |
Use of a thienotriazolodiazephine to increase apolipoprotein A-I levels
|
US5893397A
(en)
|
1996-01-12 |
1999-04-13 |
Bioject Inc. |
Medication vial/syringe liquid-transfer apparatus
|
EP0934940A1
(en)
|
1996-06-12 |
1999-08-11 |
Japan Tobacco Inc. |
Cytokine production inhibitors, triazepine compounds, and intermediates thereof
|
US5693641A
(en)
|
1996-08-16 |
1997-12-02 |
Berlex Laboratories Inc. |
Bicyclic pyrimidine derivatives and their use as anti-coagulants
|
CN1109037C
(zh)
|
1996-09-13 |
2003-05-21 |
三菱制药株式会社 |
噻吩并-***并二氮杂䓬化合物及其医药用途
|
US6444664B1
(en)
|
1997-04-18 |
2002-09-03 |
Nederlandse Organisatie Voor Toegepast - Natuurweten Schappelijk Onderzoek (Tno) |
Method for controlling the plasma level of lipoproteins to treat alzheimeris disease
|
US5993412A
(en)
|
1997-05-19 |
1999-11-30 |
Bioject, Inc. |
Injection apparatus
|
JPH11228576A
(ja)
|
1997-12-10 |
1999-08-24 |
Japan Tobacco Inc |
アポトーシス抑制剤
|
FR2779652B1
(fr)
|
1998-06-15 |
2001-06-08 |
Sod Conseils Rech Applic |
Utilisation de diazepines pour la preparation de medicaments destines a traiter les etats pathologiques ou les maladies dans lesquels un des recepteurs de la somatostatine est implique
|
US6413981B1
(en)
|
1999-08-12 |
2002-07-02 |
Ortho-Mcneil Pharamceutical, Inc. |
Bicyclic heterocyclic substituted phenyl oxazolidinone antibacterials, and related compositions and methods
|
US7589167B2
(en)
|
2000-02-22 |
2009-09-15 |
J. David Gladstone Institutes |
ZA loops of bromodomains
|
AU2001264303A1
(en)
|
2000-06-16 |
2001-12-24 |
Mitsubishi Pharma Corporation |
Compositions controlling release ph range and/or speed
|
US6552037B2
(en)
|
2000-06-30 |
2003-04-22 |
Neurogen Corporation |
2-Substituted imidazo[1,2-A]pyridine derivatives
|
US20060142257A1
(en)
|
2001-01-19 |
2006-06-29 |
Eberhard Nieschlag |
Male contraceptive formulation comprising norethisterone
|
US6979682B2
(en)
|
2001-02-23 |
2005-12-27 |
Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College |
Platelet-activating factor antagonist inhibition of angiogenesis and tumor growth induced by basic fibroblast
|
BR0211256A
(pt)
|
2001-07-20 |
2004-07-27 |
Novo Nordisk Healthcare Ag |
Composição farmacêutica, kit, usos de um polipeptìdeo relacionado ao fator vii ou fator vii em combinação com um polipeptìdeo relacionado ao fator xi ou fator xi e de uma composição, e, métodos para tratar de episódios de hemorragia em um paciente, para reduzir o tempo de coagulação em um paciente, para intensificar a hemostasia em um paciente, para prolongar o tempo de lise do coágulo e para aumentar a resistência do coágulo em um paciente
|
JP3876254B2
(ja)
|
2001-09-04 |
2007-01-31 |
ベーリンガー インゲルハイム ファルマ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト |
新規なジヒドロプテリジノン、その製造方法及びその医薬組成物としての使用
|
US6806272B2
(en)
|
2001-09-04 |
2004-10-19 |
Boehringer Ingelheim Pharma Kg |
Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
|
US20030216758A1
(en)
|
2001-12-28 |
2003-11-20 |
Angiotech Pharmaceuticals, Inc. |
Coated surgical patches
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
JP3096299U
(ja)
|
2003-02-20 |
2003-09-12 |
宇輪工業股▲ふん▼有限公司 |
足踏み式健康器
|
EP1599478B1
(de)
|
2003-02-26 |
2007-05-09 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
Dihydropteridinone, verfahren zu deren herstellung und deren verwendung als arzneimittel
|
US6861422B2
(en)
|
2003-02-26 |
2005-03-01 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Dihydropteridinones, processes for preparing them and their use as pharmaceutical compositions
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
WO2005002526A2
(en)
|
2003-07-01 |
2005-01-13 |
President And Fellows Of Harvard College |
Method and compositions for treatment of viral infections
|
EP1663992A1
(en)
|
2003-09-18 |
2006-06-07 |
Novartis AG |
2,4-di (phenylamino) pyrimidines useful in the treatment of proliferative disorders
|
EP1528056A1
(en)
|
2003-10-29 |
2005-05-04 |
Academisch Ziekenhuis bij de Universiteit van Amsterdam |
Deoxynojirimycin analogues and their uses as glucosylceramidase inhibitors
|
US7759485B2
(en)
|
2004-08-14 |
2010-07-20 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of dihydropteridinones
|
US7728134B2
(en)
|
2004-08-14 |
2010-06-01 |
Boehringer Ingelheim International Gmbh |
Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament
|
US20060035903A1
(en)
|
2004-08-14 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Storage stable perfusion solution for dihydropteridinones
|
US20060074088A1
(en)
|
2004-08-14 |
2006-04-06 |
Boehringer Ingelheim International Gmbh |
Dihydropteridinones for the treatment of cancer diseases
|
US20060058311A1
(en)
|
2004-08-14 |
2006-03-16 |
Boehringer Ingelheim International Gmbh |
Combinations for the treatment of diseases involving cell proliferation
|
GB0419161D0
(en)
|
2004-08-27 |
2004-09-29 |
Novartis Ag |
Organic compounds
|
WO2006021548A1
(de)
|
2004-08-27 |
2006-03-02 |
Boehringer Ingelheim International Gmbh |
Dihydropteridinone, verfahren zu deren herstellung und deren verwendung als arzneimittel
|
CN1759834B
(zh)
|
2004-09-17 |
2010-06-23 |
中国医学科学院医药生物技术研究所 |
黄连素或其与辛伐他汀联合在制备用于预防或治疗与血脂有关疾病或症状的产品中用途
|
TWI447120B
(zh)
|
2005-05-30 |
2014-08-01 |
Mitsubishi Tanabe Pharma Corp |
噻吩并***并苯二氮呯化合物、其醫藥上之用途
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
KR101312225B1
(ko)
|
2005-06-08 |
2013-09-26 |
리겔 파마슈티칼스, 인크. |
Jak 경로의 억제를 위한 조성물 및 방법
|
WO2007014838A1
(en)
|
2005-08-03 |
2007-02-08 |
Boehringer Ingelheim International Gmbh |
Dihydropteridinones in the treatment of respiratory diseases
|
US8133900B2
(en)
|
2005-11-01 |
2012-03-13 |
Targegen, Inc. |
Use of bi-aryl meta-pyrimidine inhibitors of kinases
|
US8604042B2
(en)
|
2005-11-01 |
2013-12-10 |
Targegen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
BR122021011787B1
(pt)
|
2005-11-01 |
2022-01-25 |
Impact Biomedicines, Inc |
Inibidores de biaril meta pirimidina de cinases, composição farmacêutica e processo para preparar uma composição farmacêutica
|
CA2634787C
(en)
|
2005-12-23 |
2014-10-21 |
Smithkline Beecham Corporation |
Azaindole inhibitors of aurora kinases
|
KR101062583B1
(ko)
|
2006-01-17 |
2011-09-06 |
에프. 호프만-라 로슈 아게 |
Gaba 수용체에 의해 알츠하이머병의 치료에 유용한아릴-아이속사졸-4-일-이미다조[1,2-a]피리딘
|
CN101420955B
(zh)
|
2006-02-14 |
2013-07-17 |
沃泰克斯药物股份有限公司 |
可用作蛋白激酶抑制剂的二氢二氮杂*
|
RU2475488C2
(ru)
|
2006-02-14 |
2013-02-20 |
Вертекс Фармасьютикалз Инкорпорейтед |
Дигидродиазепины, которые можно использовать в качестве ингибиторов протеинкиназ
|
US20070218135A1
(en)
|
2006-03-14 |
2007-09-20 |
Glenmark Pharmaceuticals Limited |
Sustained release matrix pharmaceutical composition
|
KR20090005137A
(ko)
|
2006-05-03 |
2009-01-12 |
노파르티스 아게 |
유기 화합물의 용도
|
US20090312336A1
(en)
|
2006-05-19 |
2009-12-17 |
Astrazeneca Ab |
Dihydropteridine compounds as anti proliferative agents
|
WO2008009909A1
(en)
|
2006-07-17 |
2008-01-24 |
Astrazeneca Ab |
Pteridimones as modulators of polo-like kinase
|
EP2078016B1
(en)
|
2006-10-19 |
2012-02-01 |
Signal Pharmaceuticals LLC |
Heteroaryl compounds, compositions thereof, and methods of treatment therewith
|
ATE542820T1
(de)
|
2006-10-25 |
2012-02-15 |
Chroma Therapeutics Ltd |
Pteridinderivate als inhibitoren der polo-like- kinase zur behandlung von krebs
|
US8338464B2
(en)
|
2006-11-30 |
2012-12-25 |
Albert Einstein College Of Medicine Of Yeshiva University |
Small molecule inhibitors of BCL6
|
JP2008156311A
(ja)
|
2006-12-26 |
2008-07-10 |
Institute Of Physical & Chemical Research |
Brd2ブロモドメイン結合剤
|
PT2114873E
(pt)
|
2006-12-26 |
2013-05-06 |
Lantheus Medical Imaging Inc |
Ligandos para imagiologia de inervação cardíaca
|
AU2008228303B2
(en)
|
2007-03-22 |
2012-04-19 |
Takeda Pharmaceutical Company Limited |
Substituted pyrimidodiazepines useful as PLK1 inhibitors
|
WO2008137081A1
(en)
|
2007-05-02 |
2008-11-13 |
The Trustees Of Columbia University In The City Of New York |
Substituted ( 5, 6 ) -dihydronaphraalenyl compounds as reversible male contraceptives
|
KR20080107050A
(ko)
|
2007-06-05 |
2008-12-10 |
울산대학교 산학협력단 |
항-cd137 단일클론 항체를 포함하는 만성이식편대숙주 질환의 예방 또는 치료용 약학적 조성물
|
US8461149B2
(en)
|
2007-08-15 |
2013-06-11 |
Vertex Pharmaceuticals Incorporated |
Compounds useful as protein kinase inhibitors
|
EP2205241B1
(en)
|
2007-09-25 |
2014-05-21 |
Takeda Pharmaceutical Company Limited |
Polo-like kinase inhibitors
|
PL2205603T3
(pl)
|
2007-09-28 |
2014-07-31 |
Cyclacel Ltd |
Pochodne pirymidyny jako inhibitory kinaz białkowych
|
US20090291938A1
(en)
|
2007-11-19 |
2009-11-26 |
Takeda Pharmaceutical Company Limited |
Polo-like kinase inhibitors
|
WO2009080638A2
(en)
|
2007-12-20 |
2009-07-02 |
Cellzome Limited |
Sulfamides as zap-70 inhibitors
|
US8476260B2
(en)
|
2007-12-28 |
2013-07-02 |
Mitsubishi Tanabe Pharma Corporation |
Antitumor agent
|
AU2009224804B2
(en)
|
2008-03-10 |
2013-12-05 |
Janssen Pharmaceutica Nv |
4-aryl-2-anilino-pyrimidines as PLK kinase inhibitors
|
CA2717529A1
(en)
|
2008-03-11 |
2009-09-17 |
Cellzome Limited |
Sulfonamides as zap-70 inhibitors
|
FR2928923B1
(fr)
|
2008-03-21 |
2010-04-23 |
Sanofi Aventis |
Derives polysubstitues de 2-heteroaryl-6-phenyl-imidazo °1,2-a!pyridines, leur preparation et leur application en therapeutiques
|
EP2112152A1
(en)
|
2008-04-22 |
2009-10-28 |
GPC Biotech AG |
Dihydropteridinones as Plk Inhibitors
|
WO2009153197A1
(en)
|
2008-06-18 |
2009-12-23 |
F. Hoffmann-La Roche Ag |
Halo-substituted pyrimidodiazepines as plkl inhibitors
|
WO2010015340A1
(en)
|
2008-08-06 |
2010-02-11 |
Bayer Schering Pharma Aktiengesellschaft |
Daa-pyridine as peripheral benzodiazepine receptor ligand for diagnostic imaging and pharmaceutical treatment
|
CN102216298B
(zh)
|
2008-09-16 |
2014-04-16 |
Csir公司 |
作为hiv-1逆转录酶抑制剂的咪唑并吡啶和咪唑并嘧啶
|
US8569288B2
(en)
*
|
2008-10-30 |
2013-10-29 |
Circomed Llc |
Thienotriazolodiazepine derivatives active on apo A
|
BRPI0921110A2
(pt)
|
2008-11-13 |
2016-02-16 |
Hoffmann La Roche |
espiro-5,6-di-hidro-4h-2,3,5,10b-tetraaza-benzo[e]azulenos
|
US9266890B2
(en)
|
2009-01-06 |
2016-02-23 |
Dana-Farber Cancer Institute, Inc. |
Pyrimido-diazepinone kinase scaffold compounds and methods of treating disorders
|
EP2389379A1
(en)
|
2009-01-23 |
2011-11-30 |
Takeda Pharmaceutical Company Limited |
Poly (ADP-Ribose) Polymerase (PARP) Inhibitors
|
CN102020643A
(zh)
|
2009-09-22 |
2011-04-20 |
上海恒瑞医药有限公司 |
二氢喋啶酮类衍生物、其制备方法及其在医药上的应用
|
MX2012003484A
(es)
|
2009-09-25 |
2012-04-20 |
Vertex Pharma |
Metodos para preparar derivados de pirimidina utiles como inhibidores de proteina cinasa.
|
GB0919431D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
EP3050885B1
(en)
|
2009-11-05 |
2017-10-18 |
GlaxoSmithKline LLC |
Benzodiazepine bromodomain inhibitor
|
GB0919433D0
(en)
*
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
EP3037423B1
(en)
|
2009-11-05 |
2017-09-20 |
Glaxosmithkline LLC |
Novel benzodiazepine compound
|
GB0919423D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
GB0919426D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
GB0919434D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Novel compounds
|
GB0919432D0
(en)
|
2009-11-05 |
2009-12-23 |
Glaxosmithkline Llc |
Use
|
EP2536725B1
(en)
|
2010-02-17 |
2015-10-28 |
Boehringer Ingelheim International GmbH |
Dihydropteridinones, method for production and use thereof
|
CA2799403C
(en)
|
2010-05-14 |
2020-01-21 |
Dana-Farber Cancer Institute, Inc. |
Compositions and methods for treating leukemia
|
EP2571875A4
(en)
|
2010-05-14 |
2013-10-30 |
Dana Farber Cancer Inst Inc |
CONTRACEPTIVE COMPOSITIONS FOR MEN AND METHODS OF USE THEREOF
|
MX2012013255A
(es)
|
2010-05-14 |
2013-02-27 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para tratar neoplasias, enfermedades inflamatorias y otros trastornos.
|
US20130252331A1
(en)
|
2010-05-14 |
2013-09-26 |
James Elliott Bradner |
Compositions and methods for modulating metabolism
|
ES2526671T3
(es)
|
2010-06-22 |
2015-01-14 |
Glaxosmithkline Llc |
Compuestos de benzotriazoldiazepina inhibidores de bromodominios
|
US20120014979A1
(en)
|
2010-07-16 |
2012-01-19 |
Alexander Dent |
Use of bcl6 inhibitors for treating autoimmune diseases
|
US9358233B2
(en)
|
2010-11-29 |
2016-06-07 |
Boehringer Ingelheim International Gmbh |
Method for treating acute myeloid leukemia
|
WO2012075456A1
(en)
|
2010-12-02 |
2012-06-07 |
Constellation Pharmaceuticals |
Bromodomain inhibitors and uses thereof
|
AR084070A1
(es)
|
2010-12-02 |
2013-04-17 |
Constellation Pharmaceuticals Inc |
Inhibidores del bromodominio y usos de los mismos
|
EP2677865A4
(en)
|
2011-02-23 |
2015-04-22 |
Icahn School Med Mount Sinai |
BROMODOMAIN INHIBITORS AS MODULATORS OF GENE EXPRESSION
|
AU2012223448B2
(en)
|
2011-02-28 |
2017-03-16 |
Epizyme, Inc. |
Substituted 6,5-fused bicyclic heteroaryl compounds
|
US9127074B2
(en)
|
2011-03-07 |
2015-09-08 |
Fondazione Telethon |
TFEB variants and uses thereof
|
GB201106799D0
(en)
|
2011-04-21 |
2011-06-01 |
Glaxosmithkline Llc |
Novel compounds
|
WO2013033268A2
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bivalent bromodomain ligands, and methods of using same
|
WO2013033269A1
(en)
|
2011-08-29 |
2013-03-07 |
Coferon, Inc. |
Bioorthogonal monomers capable of dimerizing and targeting bromodomains and methods of using same
|
DE102011082013A1
(de)
|
2011-09-01 |
2013-03-07 |
Bayer Pharma AG |
6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
|
WO2013097052A1
(en)
*
|
2011-12-30 |
2013-07-04 |
Abbott Laboratories |
Bromodomain inhibitors
|
WO2013123521A1
(en)
|
2012-02-17 |
2013-08-22 |
Nexbio, Inc. |
Methods, Compounds and Compositions for Treatment of Parainfluenza Virus in Immunocompromised Patients
|
EP2830629A4
(en)
|
2012-03-28 |
2016-01-20 |
Icahn School Of Medicine Mount Sinai |
COMPOSITIONS AND METHODS FOR REACTING LATENT IMMUNODEFICIENCY VIRUS
|
CA2878996C
(en)
|
2012-08-08 |
2021-09-14 |
Novomatic Ag |
Method of and system for tracking gaming activity
|
RU2015115634A
(ru)
|
2012-09-28 |
2016-11-20 |
Онкоэтикс Гмбх |
Фармацевтический состав, содержащий соединения тиенотриазолодиазепина
|
EP2917203B1
(en)
|
2012-11-02 |
2019-04-03 |
Dana-Farber Cancer Institute, Inc. |
Method for identifying myc inhibitors
|
US9609495B2
(en)
*
|
2012-11-16 |
2017-03-28 |
Verizon Patent And Licensing Inc. |
Central information management system
|
JP2016504990A
(ja)
|
2012-12-20 |
2016-02-18 |
バイエル ファーマ アクチエンゲゼルシャフト |
Betタンパク質抑制性ジヒドロピリドピラジノン
|
US20140254659A1
(en)
|
2013-03-11 |
2014-09-11 |
Mediatek Inc. |
Video coding method using at least evaluated visual quality and related video coding apparatus
|
TW201444843A
(zh)
|
2013-03-11 |
2014-12-01 |
Abbvie Inc |
溴區結構域蛋白抑制劑
|
CN105026403B
(zh)
|
2013-03-12 |
2018-05-18 |
艾伯维公司 |
四环布罗莫结构域抑制剂
|
CA2905070A1
(en)
*
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Methods of treating cancer and preventing cancer drug resistance
|
WO2014159392A1
(en)
|
2013-03-14 |
2014-10-02 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
RU2016105108A
(ru)
|
2013-07-25 |
2017-08-30 |
Дана-Фарбер Кэнсер Инститьют, Инк. |
Ингибиторы факторов транскрипции и их применение
|
CA2922503C
(en)
|
2013-09-19 |
2021-10-26 |
Dana-Farber Cancer Institute, Inc. |
Methods of bh3 profiling
|
WO2015081284A1
(en)
|
2013-11-26 |
2015-06-04 |
Coferon, Inc. |
Bivalent bromodomain ligands, and methods of using same
|
WO2015081280A1
(en)
|
2013-11-26 |
2015-06-04 |
Coferon, Inc. |
Bromodomain ligands capable of dimerizing in an aqueous solution
|
JP2016539990A
(ja)
*
|
2013-12-10 |
2016-12-22 |
アッヴィ・インコーポレイテッド |
ブロモドメイン阻害薬
|
WO2015117087A1
(en)
|
2014-01-31 |
2015-08-06 |
Dana-Farber Cancer Institute, Inc. |
Uses of diazepane derivatives
|
CN105939607A
(zh)
|
2014-01-31 |
2016-09-14 |
达纳-法伯癌症研究所股份有限公司 |
二氢蝶啶酮衍生物及其用途
|
MX2016009974A
(es)
|
2014-01-31 |
2016-10-31 |
Dana Farber Cancer Inst Inc |
Derivados de diaminopirimidina bencensulfona y sus usos.
|
MX2016009976A
(es)
|
2014-01-31 |
2016-11-15 |
Dana Farber Cancer Inst Inc |
Derivados de diazepam y sus usos.
|
EP3110819A4
(en)
|
2014-02-26 |
2017-08-02 |
Kyorin Pharmaceutical Co., Ltd. |
Heterocyclic compounds
|
AU2015222805B2
(en)
|
2014-02-28 |
2020-05-21 |
Tensha Therapeutics, Inc. |
Treatment of conditions associated with hyperinsulinaemia
|
US20180228907A1
(en)
|
2014-04-14 |
2018-08-16 |
Arvinas, Inc. |
Cereblon ligands and bifunctional compounds comprising the same
|
CN106715437A
(zh)
|
2014-08-08 |
2017-05-24 |
达纳-法伯癌症研究所股份有限公司 |
二氮杂环庚烷衍生物及其用途
|
EP3177147A4
(en)
|
2014-08-08 |
2018-01-24 |
Dana-Farber Cancer Institute, Inc. |
Dihydropteridinone derivatives and uses thereof
|
JP2017537166A
(ja)
|
2014-12-05 |
2017-12-14 |
エイチ リー モフィット キャンサー センター アンド リサーチ インスティテュート インコーポレイテッド |
癌免疫療法におけるアジュバントとしてのブロモドメイン阻害剤
|
US9694084B2
(en)
|
2014-12-23 |
2017-07-04 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce targeted protein degradation through bifunctional molecules
|
EP3256470B1
(en)
|
2014-12-23 |
2023-07-26 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce targeted protein degradation through bifunctional molecules
|
AU2016232705C1
(en)
|
2015-03-18 |
2021-06-17 |
Arvinas, Inc. |
Compounds and methods for the enhanced degradation of targeted proteins
|
AU2016276963C1
(en)
|
2015-06-12 |
2021-08-05 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
WO2017007612A1
(en)
|
2015-07-07 |
2017-01-12 |
Dana-Farber Cancer Institute, Inc. |
Methods to induce targeted protein degradation through bifunctional molecules
|
WO2017024318A1
(en)
|
2015-08-06 |
2017-02-09 |
Dana-Farber Cancer Institute, Inc. |
Targeted protein degradation to attenuate adoptive t-cell therapy associated adverse inflammatory responses
|
US10772962B2
(en)
|
2015-08-19 |
2020-09-15 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of bromodomain-containing proteins
|
KR20180043837A
(ko)
|
2015-09-04 |
2018-04-30 |
에프. 호프만-라 로슈 아게 |
페녹시메틸 유도체
|
AU2016319638B2
(en)
|
2015-09-09 |
2021-02-11 |
Jubilant Biosys Limited |
Tricyclic fused pyridin-2-one derivatives and their use as BRD4 inhibitors
|
CR20180199A
(es)
|
2015-09-11 |
2018-05-25 |
Dana Farber Cancer Inst Inc |
Acetamida tienotriazolodiazepinas y usos de las mismas
|
CA2998250A1
(en)
|
2015-09-11 |
2017-03-16 |
Boehringer Ingelheim International Gmbh |
Pyrazolyl-substituted heteroaryls and their use as medicaments
|
US11306105B2
(en)
|
2015-09-11 |
2022-04-19 |
Dana-Farber Cancer Institute, Inc. |
Cyano thienotriazolodiazepines and uses thereof
|
US10913752B2
(en)
|
2015-11-25 |
2021-02-09 |
Dana-Farber Cancer Institute, Inc. |
Bivalent bromodomain inhibitors and uses thereof
|
WO2017091627A1
(en)
|
2015-11-25 |
2017-06-01 |
Gilead Apollo, Llc |
Fungicidal compositions containing derivatives of 2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidine
|
EP3888658B1
(en)
|
2015-11-25 |
2023-12-27 |
Effector Therapeutics, Inc. |
Eif4-a-inhibiting compounds and methods related thereto
|
JP2018536661A
(ja)
|
2015-11-25 |
2018-12-13 |
ギリアド アポロ, エルエルシー |
トリアゾールacc阻害剤およびその使用
|
MY197345A
(en)
|
2015-11-25 |
2023-06-14 |
Visterra Inc |
Antibody molecules to april and uses thereof
|
EA201890949A1
(ru)
|
2015-11-25 |
2018-12-28 |
Джилид Аполло, Ллс |
СЛОЖНОЭФИРНЫЕ ИНГИБИТОРЫ АЦЕТИЛ-КоА-КАРБОКСИЛАЗЫ И ВАРИАНТЫ ИХ ПРИМЕНЕНИЯ
|
CA3004796C
(en)
|
2015-11-25 |
2023-11-14 |
Gilead Apollo, Llc |
Pyrazole acc inhibitors and uses thereof
|
CA3006029C
(en)
|
2015-12-01 |
2020-08-04 |
Nihon Nohyaku Co., Ltd. |
3h-pyrrolopyridine compound, n-oxide thereof or salt thereof, agricultural and horticultural insecticide comprising the compound and method for using the same
|
EP3455218A4
(en)
|
2016-05-10 |
2019-12-18 |
C4 Therapeutics, Inc. |
C3 CARBON-BASED GLUTARIMIDE DEGRONIMERS FOR TARGET PROTEIN REDUCTION
|
WO2017197051A1
(en)
|
2016-05-10 |
2017-11-16 |
C4 Therapeutics, Inc. |
Amine-linked c3-glutarimide degronimers for target protein degradation
|
WO2017201069A1
(en)
|
2016-05-18 |
2017-11-23 |
Biotheryx, Inc. |
Oxoindoline derivatives as protein function modulators
|
GB201608797D0
(en)
|
2016-05-19 |
2016-07-06 |
Ucb Biopharma Sprl |
Therapeutic use
|
WO2018064589A1
(en)
|
2016-09-29 |
2018-04-05 |
Dana-Farber Cancer Institute, Inc. |
Targeted protein degradation using a mutant e3 ubiquitin ligase
|