FI941245A - Menetelmä 2'-deoksiguanosiinin asyylijohdannaisten valmistamiseksi - Google Patents
Menetelmä 2'-deoksiguanosiinin asyylijohdannaisten valmistamiseksi Download PDFInfo
- Publication number
- FI941245A FI941245A FI941245A FI941245A FI941245A FI 941245 A FI941245 A FI 941245A FI 941245 A FI941245 A FI 941245A FI 941245 A FI941245 A FI 941245A FI 941245 A FI941245 A FI 941245A
- Authority
- FI
- Finland
- Prior art keywords
- acyl derivatives
- deoxyguanosine
- preparation
- enhancing
- haematopoesis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
- A61K31/708—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid having oxo groups directly attached to the purine ring system, e.g. guanosine, guanylic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11592387A | 1987-10-28 | 1987-10-28 | |
US11592387 | 1987-10-28 | ||
PCT/US1988/003824 WO1989003838A1 (en) | 1987-10-28 | 1988-10-27 | Acyl deoxyribonucleoside derivatives and uses thereof |
US8803824 | 1988-10-27 | ||
FI893100 | 1989-06-26 | ||
FI893100A FI91764C (fi) | 1987-10-28 | 1989-06-26 | Analogiamenetelmä asyylideoksiribonukleosidijohdannaisten valmistamiseksi |
Publications (4)
Publication Number | Publication Date |
---|---|
FI941245A0 FI941245A0 (fi) | 1994-03-16 |
FI941245A true FI941245A (fi) | 1994-03-16 |
FI97891B FI97891B (fi) | 1996-11-29 |
FI97891C FI97891C (fi) | 1997-03-10 |
Family
ID=22364166
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI893100A FI91764C (fi) | 1987-10-28 | 1989-06-26 | Analogiamenetelmä asyylideoksiribonukleosidijohdannaisten valmistamiseksi |
FI941245A FI97891C (fi) | 1987-10-28 | 1994-03-16 | Menetelmä 2'-deoksiguanosiinin asyylijohdannaisten valmistamiseksi |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI893100A FI91764C (fi) | 1987-10-28 | 1989-06-26 | Analogiamenetelmä asyylideoksiribonukleosidijohdannaisten valmistamiseksi |
Country Status (15)
Country | Link |
---|---|
US (1) | US6020320A (fi) |
EP (2) | EP0355131B1 (fi) |
JP (2) | JP2637534B2 (fi) |
KR (1) | KR890701609A (fi) |
AT (2) | ATE142221T1 (fi) |
CA (1) | CA1329932C (fi) |
DE (2) | DE3855513T2 (fi) |
DK (1) | DK174400B1 (fi) |
FI (2) | FI91764C (fi) |
HK (1) | HK1004854A1 (fi) |
IL (1) | IL88204A (fi) |
IN (1) | IN167609B (fi) |
NO (1) | NO174392C (fi) |
WO (1) | WO1989003838A1 (fi) |
ZA (1) | ZA888083B (fi) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5968914A (en) * | 1987-10-28 | 1999-10-19 | Pro-Neuron, Inc. | Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides |
US7776838B1 (en) | 1987-10-28 | 2010-08-17 | Wellstat Therapeutics Corporation | Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides |
US6329350B1 (en) * | 1987-10-28 | 2001-12-11 | Pro-Neuron, Inc. | Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis |
US7173017B1 (en) | 1987-10-28 | 2007-02-06 | Wellstat Therapeutics Corporation | Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis |
US6743782B1 (en) * | 1987-10-28 | 2004-06-01 | Wellstat Therapeutics Corporation | Acyl deoxyribonucleoside derivatives and uses thereof |
US5470838A (en) | 1987-10-28 | 1995-11-28 | Pro-Neuron, Inc. | Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine |
US6060459A (en) | 1987-10-28 | 2000-05-09 | Pro-Neuron, Inc. | Enhancing blood cell count with oxypurine nucleosides |
US5736531A (en) * | 1987-10-28 | 1998-04-07 | Pro-Neuron, Inc. | Compositions of chemotherapeutic agent or antiviral agent with acylated pyrimidine nucleosides |
IE980216A1 (en) * | 1989-04-17 | 2000-02-23 | Scotia Holdings Plc | Anti-virals |
WO1992013561A1 (en) * | 1991-02-08 | 1992-08-20 | Pro-Neuron, Inc. | Oxypurine nucleosides and their congeners, and acyl derivatives thereof, for improvement of hematopoiesis |
DK0594667T3 (da) * | 1991-07-05 | 2001-11-12 | Pro Neuron Inc | Behandling af kemoterapeutiske og antivirale, aktive stoffers toksiske virkning med acylerede pyrimidinnucleosider |
GB2260319B (en) * | 1991-10-07 | 1995-12-06 | Norsk Hydro As | Acyl derivatives of nucleosides and nucleoside analogues having anti-viral activity |
JPH08503699A (ja) * | 1992-12-08 | 1996-04-23 | プロ − ニューロン,インコーポレーテッド | 全身性炎症と炎症性肝炎の治療のためのピリミジンヌクレオチド前駆体 |
US5641758A (en) * | 1993-11-10 | 1997-06-24 | Kluge; Michael | Cytarabine derivatives, the preparation and use thereof |
JP4408450B2 (ja) | 1994-07-01 | 2010-02-03 | ウェルスタット セラピューティクス コーポレイション | 全身性炎症および炎症性肝炎の処置のためのピリミジンヌクレオチド前駆体 |
EP0882734B1 (en) * | 1997-06-02 | 2009-08-26 | F. Hoffmann-La Roche Ag | 5'-Deoxy-cytidine derivatives |
US20020006913A1 (en) | 1997-11-04 | 2002-01-17 | Von Borstel Reid W. | Antimutagenic compositions for treatment and prevention of photodamage to skin |
WO1999030705A1 (en) * | 1997-12-16 | 1999-06-24 | William Darwin Garner | Reduction of uv induced skin cancer by topical amines |
US6444652B1 (en) | 1998-08-10 | 2002-09-03 | Novirio Pharmaceuticals Limited | β-L-2'-deoxy-nucleosides for the treatment of hepatitis B |
DK1104436T3 (da) | 1998-08-10 | 2006-04-03 | Centre Nat Rech Scient | Beta-L-2'-deoxy-nukleosider til behandling af hepatitis B-virus |
PT1171137E (pt) | 1999-02-23 | 2008-03-17 | Univ California | Utilização de triacetiluridina para o tratamento de perturbações mitocondriais |
US6576619B2 (en) * | 1999-05-24 | 2003-06-10 | Cv Therapeutics, Inc. | Orally active A1 adenosine receptor agonists |
US6787526B1 (en) | 2000-05-26 | 2004-09-07 | Idenix Pharmaceuticals, Inc. | Methods of treating hepatitis delta virus infection with β-L-2′-deoxy-nucleosides |
US6875751B2 (en) | 2000-06-15 | 2005-04-05 | Idenix Pharmaceuticals, Inc. | 3′-prodrugs of 2′-deoxy-β-L-nucleosides |
DE10117615A1 (de) * | 2001-04-07 | 2002-10-10 | Max Delbrueck Centrum | Verwendung von Nucleosiden, Nucleobasen und deren Derivaten zur verbesserten Gewinnung von adulten Stammzellen |
TWI244393B (en) | 2002-08-06 | 2005-12-01 | Idenix Pharmaceuticals Inc | Crystalline and amorphous forms of beta-L-2'-deoxythymidine |
WO2004024095A2 (en) | 2002-09-13 | 2004-03-25 | Idenix (Cayman) Limited | ß-L-2'-DEOXYNUCLEOSIDES FOR THE TREATMENT OF RESISTANT HBV STRAINS AND COMBINATION THERAPIES |
CA2695950C (en) | 2007-08-16 | 2016-06-07 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Compositions containing nucleosides and manganese and their uses |
CA2751563A1 (en) * | 2009-02-04 | 2010-08-12 | Jelena Mann | Methods of inhibiting fibrogenesis and treating fibrotic disease |
CA3012801A1 (en) | 2010-04-29 | 2011-11-10 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Compositions containing purine and pyrimidine nucleosides, peptides, and manganese and their uses |
US9446064B2 (en) | 2013-03-14 | 2016-09-20 | Epizyme, Inc. | Combination therapy for treating cancer |
AU2021202658A1 (en) | 2021-04-28 | 2022-11-17 | Fondazione Telethon | Gene therapy |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3847898A (en) * | 1969-05-27 | 1974-11-12 | Upjohn Co | N4-trihaloethoxy carbonyl arabino-furanosyl cytosine 5'-esters |
US3585188A (en) * | 1969-06-16 | 1971-06-15 | Takeda Chemical Industries Ltd | Process for producing 2'-deoxyuridine |
DE1941942A1 (de) * | 1969-08-18 | 1971-03-04 | Sylven Bengt Prof Dr | Neues pharmazeutisches Mittel |
FR2096712A1 (en) * | 1970-06-29 | 1972-02-25 | Giraux Georges | Steroid/b group vitamin compsns - for prevention and treatment of skin-photosensitivity disorders |
US3894000A (en) * | 1971-01-27 | 1975-07-08 | Upjohn Co | Ara-cytidine derivatives and process of preparation |
US3975367A (en) * | 1971-06-08 | 1976-08-17 | The Upjohn Company | Arabinofuranosyl N4 -aminoacyl cytosine containing compounds |
DE2147094A1 (de) * | 1971-09-21 | 1973-04-05 | Robugen Gmbh | Virostatisch wirksames arzneimittel |
US3991045A (en) * | 1973-05-30 | 1976-11-09 | Asahi Kasei Kogyo Kabushiki Kaisha | N4 -acylarabinonucleosides |
US4048432A (en) * | 1976-05-17 | 1977-09-13 | Parke, Davis & Company | 9-(3,5-Di-O-acyl-β-D-arabinofuranosyl)adenine compounds and method for their production |
FR2358155A1 (fr) * | 1976-07-15 | 1978-02-10 | Lapinet Eugene | Composition pour le traitement et la prevention de l'irritation et de l'inflammation de la peau, de l'oeil et des muqueuses |
US4675189A (en) * | 1980-11-18 | 1987-06-23 | Syntex (U.S.A.) Inc. | Microencapsulation of water soluble active polypeptides |
JPS5791994A (en) * | 1980-11-26 | 1982-06-08 | Fuji Kagaku Kogyo Kk | 5'-o-(n-alkylcarbamoylalanyl)-5-fluorouridine and its preparation |
DE3100478A1 (de) | 1981-01-09 | 1982-08-12 | Dr. Thilo & Co GmbH, 8021 Sauerlach | 5'ester von pyrimidinnucleosiden mit antiviraler wirksamkeit, verfahren zur herstellung und daraus hergestellte arzneimittel |
JPS57156418A (en) * | 1981-03-19 | 1982-09-27 | Sumitomo Chem Co Ltd | Carcinostatic |
JPS5849315A (ja) * | 1981-09-18 | 1983-03-23 | Mitsui Pharmaceut Inc | 抗腫瘍剤 |
JPS58167589A (ja) * | 1982-03-26 | 1983-10-03 | Nissan Chem Ind Ltd | ピラゾ−ル誘導体、その製法および該誘導体を含有する除草剤 |
JPS58167598A (ja) * | 1982-03-29 | 1983-10-03 | Tanabe Seiyaku Co Ltd | アデノシン誘導体及びその製法 |
FR2536278A1 (fr) * | 1982-11-18 | 1984-05-25 | Dupont Michele | Nouvelle composition therapeutique utile notamment pour la cicatrisation des plaies |
DE3319282A1 (de) * | 1983-05-27 | 1984-11-29 | Gödecke AG, 1000 Berlin | Verwendung von adenosin bei der behandlung von herpes |
JPS59219235A (ja) * | 1983-05-30 | 1984-12-10 | Mitsui Toatsu Chem Inc | 消化性潰瘍用剤 |
DE3481191D1 (de) * | 1983-07-20 | 1990-03-08 | Teijin Ltd | Antineoplastisches mittel. |
JPS6028929A (ja) * | 1983-07-28 | 1985-02-14 | Hokuriku Seiyaku Co Ltd | 2’−デオキシグアノシンを有効成分とする消化性潰瘍治療剤 |
JPS6064907A (ja) * | 1983-09-17 | 1985-04-13 | Risuburan Prod:Kk | 水性ゲル状化粧料 |
JPS60126220A (ja) * | 1983-12-09 | 1985-07-05 | Otsuka Pharmaceut Factory Inc | 核酸成分組成物 |
FR2556727B1 (fr) * | 1983-12-19 | 1990-01-19 | Biostabilex Labo Pharma | Nouvelles compositions therapeutiques a base d'adn a haut poids moleculaire et leur procede de preparation |
JPS60174797A (ja) | 1984-02-21 | 1985-09-09 | Funai Corp | Ν−アロイルチミジン誘導体ならびに抗腫瘍活性物質の毒性低下剤 |
WO1987000435A1 (fr) * | 1985-07-22 | 1987-01-29 | Teijin Limited | Medicament antiviral |
US4762823A (en) * | 1985-10-16 | 1988-08-09 | Sloan-Kettering Institute For Cancer Research | Nucleosides of 5-monofluoromethyluracil and 5-difluoromethyluracil |
ATE146077T1 (de) * | 1986-09-22 | 1996-12-15 | Janssen Pharmaceutica Nv | Serotonin-antagonisten zur behandlung von wunden |
US4758533A (en) * | 1987-09-22 | 1988-07-19 | Xmr Inc. | Laser planarization of nonrefractory metal during integrated circuit fabrication |
US5246708A (en) * | 1987-10-28 | 1993-09-21 | Pro-Neuron, Inc. | Methods for promoting wound healing with deoxyribonucleosides |
JP2638949B2 (ja) * | 1988-07-06 | 1997-08-06 | トヨタ自動車株式会社 | 誘導電導機の制御方法 |
JPH0628929A (ja) * | 1992-07-09 | 1994-02-04 | Fujikura Ltd | 絶縁電線 |
JPH0634913A (ja) * | 1992-07-15 | 1994-02-10 | Oki Electric Ind Co Ltd | 密着イメージセンサの光学構成方法 |
JP3251060B2 (ja) * | 1992-08-18 | 2002-01-28 | 電気化学工業株式会社 | 窒化珪素粉末 |
JPH06123917A (ja) * | 1992-08-24 | 1994-05-06 | Fuji Photo Film Co Ltd | 写真作製装置 |
JP3454951B2 (ja) * | 1994-12-12 | 2003-10-06 | 株式会社半導体エネルギー研究所 | 半導体装置の作製方法 |
-
1988
- 1988-10-27 EP EP88910239A patent/EP0355131B1/en not_active Expired - Lifetime
- 1988-10-27 ZA ZA888083A patent/ZA888083B/xx unknown
- 1988-10-27 EP EP95203050A patent/EP0712629B1/en not_active Expired - Lifetime
- 1988-10-27 KR KR1019890701195A patent/KR890701609A/ko not_active IP Right Cessation
- 1988-10-27 CA CA000581430A patent/CA1329932C/en not_active Expired - Fee Related
- 1988-10-27 AT AT88910239T patent/ATE142221T1/de not_active IP Right Cessation
- 1988-10-27 DE DE3855513T patent/DE3855513T2/de not_active Expired - Fee Related
- 1988-10-27 WO PCT/US1988/003824 patent/WO1989003838A1/en active IP Right Grant
- 1988-10-27 DE DE3856557T patent/DE3856557T2/de not_active Expired - Fee Related
- 1988-10-27 JP JP63509388A patent/JP2637534B2/ja not_active Expired - Fee Related
- 1988-10-27 AT AT95203050T patent/ATE243039T1/de not_active IP Right Cessation
- 1988-10-28 IL IL8820488A patent/IL88204A/en not_active IP Right Cessation
- 1988-10-28 IN IN754/MAS/88A patent/IN167609B/en unknown
-
1989
- 1989-06-26 NO NO892642A patent/NO174392C/no not_active IP Right Cessation
- 1989-06-26 FI FI893100A patent/FI91764C/fi not_active IP Right Cessation
- 1989-06-27 DK DK198903180A patent/DK174400B1/da not_active IP Right Cessation
-
1993
- 1993-11-17 US US08/153,163 patent/US6020320A/en not_active Expired - Fee Related
-
1994
- 1994-03-16 FI FI941245A patent/FI97891C/fi not_active IP Right Cessation
- 1994-10-26 JP JP6299158A patent/JP2764014B2/ja not_active Expired - Lifetime
-
1998
- 1998-04-29 HK HK98103631A patent/HK1004854A1/xx not_active IP Right Cessation
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