UA79749C2
(en)
|
1996-10-18 |
2007-07-25 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
|
WO2001079246A2
(en)
*
|
2000-04-13 |
2001-10-25 |
Pharmasset, Ltd. |
3'-or 2'-hydroxymethyl substituted nucleoside derivatives for treatment of hepatitis virus infections
|
MY164523A
(en)
*
|
2000-05-23 |
2017-12-29 |
Univ Degli Studi Cagliari |
Methods and compositions for treating hepatitis c virus
|
EA200601591A1
(ru)
|
2000-05-26 |
2007-02-27 |
Айденикс (Кайман) Лимитед |
Применение рибонуклеозидных соединений для лечения флавивирусных и пестивирусных инфекций
|
SV2003000617A
(es)
|
2000-08-31 |
2003-01-13 |
Lilly Co Eli |
Inhibidores de la proteasa peptidomimetica ref. x-14912m
|
US8481712B2
(en)
*
|
2001-01-22 |
2013-07-09 |
Merck Sharp & Dohme Corp. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
AU2002243791B2
(en)
*
|
2001-01-22 |
2006-06-29 |
Isis Pharmaceuticals, Inc. |
Nucleoside derivatives as inhibitors of RNA-dependent RNA viral polymerase
|
EP2050822B1
(en)
|
2001-01-23 |
2013-07-31 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Hepatitis C virus replicons and replicon enhanced cells
|
US6905669B2
(en)
|
2001-04-24 |
2005-06-14 |
Supergen, Inc. |
Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
|
GB0114286D0
(en)
|
2001-06-12 |
2001-08-01 |
Hoffmann La Roche |
Nucleoside Derivatives
|
US7138376B2
(en)
*
|
2001-09-28 |
2006-11-21 |
Idenix Pharmaceuticals, Inc. |
Methods and compositions for treating hepatitis C virus using 4'-modified nucleosides
|
AU2002353164A1
(en)
*
|
2001-12-17 |
2003-06-30 |
Ribapharm Inc. |
Unusual nucleoside libraries, compounds, and preferred uses as antiviral and anticancer agents
|
AU2002341942A1
(en)
*
|
2002-01-17 |
2003-09-02 |
Ribapharm Inc. |
Sugar modified nucleosides as viral replication inhibitors
|
WO2003062256A1
(en)
*
|
2002-01-17 |
2003-07-31 |
Ribapharm Inc. |
2'-beta-modified-6-substituted adenosine analogs and their use as antiviral agents
|
WO2003068244A1
(en)
*
|
2002-02-13 |
2003-08-21 |
Merck & Co., Inc. |
Methods of inhibiting orthopoxvirus replication with nucleoside compounds
|
WO2003085375A2
(en)
*
|
2002-04-04 |
2003-10-16 |
Achillion Pharmaceuticals, Inc. |
Hcv antiviral and cytotoxicity drug screening assay
|
EP1495040A4
(en)
*
|
2002-04-12 |
2006-01-25 |
Achillion Pharmaceuticals Inc |
PROCESS FOR THE SYNTHESIS OF BETA-L-FLUORO-2 ', 3'-DIDEOXY-DIDEHYDROCYTIDINE (BETA-L-FD4C)
|
US20070010489A1
(en)
|
2002-04-26 |
2007-01-11 |
Arimilli Murty N |
Cellular accumulation of phosphonate analogs of hiv protease inhibitor compounds
|
US7247621B2
(en)
|
2002-04-30 |
2007-07-24 |
Valeant Research & Development |
Antiviral phosphonate compounds and methods therefor
|
MXPA04010983A
(es)
*
|
2002-05-06 |
2005-02-14 |
Genelabs Tech Inc |
Derivados de nucleosidos para tratar infecciones por el virus de la hepatitis c.
|
US6982253B2
(en)
|
2002-06-05 |
2006-01-03 |
Supergen, Inc. |
Liquid formulation of decitabine and use of the same
|
EP1551421A2
(en)
*
|
2002-06-21 |
2005-07-13 |
Merck & Co. Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
EP1572945A2
(en)
*
|
2002-06-27 |
2005-09-14 |
Merck & Co., Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
BR0312271A
(pt)
|
2002-06-28 |
2007-11-06 |
Idenix Cayman Ltd |
compostos, composições e seus usos para o tratamento de infecções por flaviviridae
|
US7608600B2
(en)
*
|
2002-06-28 |
2009-10-27 |
Idenix Pharmaceuticals, Inc. |
Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections
|
BR0312278A
(pt)
*
|
2002-06-28 |
2007-06-19 |
Idenix Cayman Ltd |
éster 2'-c-metil-3'-o-l-valina de ribofuranosil citidina para tratamento de infecções por flaviviridae
|
CN101172993A
(zh)
|
2002-06-28 |
2008-05-07 |
埃迪尼克斯(开曼)有限公司 |
用于治疗黄病毒感染的2′-c-甲基-3′-o-l-缬氨酸酯核糖呋喃基胞苷
|
GB0215293D0
(en)
|
2002-07-03 |
2002-08-14 |
Rega Foundation |
Viral inhibitors
|
AU2003269902A1
(en)
*
|
2002-07-16 |
2004-02-02 |
Isis Pharmaceuticals, Inc. |
Nucleoside derivatives as inhibitors of rna-dependent rna viral polymerase
|
AU2003256619A1
(en)
|
2002-07-24 |
2004-02-09 |
Isis Pharmaceuticals, Inc. |
Pyrrolopyrimidine thionucleoside analogs as antivirals
|
KR20050037559A
(ko)
*
|
2002-07-25 |
2005-04-22 |
마이크로로직스 바이오테크, 인코포레이티드 |
항바이러스성 7-데아자 d-뉴클레오시드 및 그의 용도
|
US20050058982A1
(en)
|
2002-07-26 |
2005-03-17 |
Chiron Corporation |
Modified small interfering RNA molecules and methods of use
|
US20040067877A1
(en)
*
|
2002-08-01 |
2004-04-08 |
Schinazi Raymond F. |
2', 3'-Dideoxynucleoside analogues for the treatment or prevention of Flaviviridae infections
|
BR0313164A
(pt)
|
2002-08-01 |
2007-07-17 |
Pharmasset Inc |
compostos com o sistema biciclo[4.2.1] nonano para o tratamento de infecções por flaviviridae
|
DE10238722A1
(de)
|
2002-08-23 |
2004-03-11 |
Bayer Ag |
Selektive Phosphodiesterase 9A-Inhibitoren als Arzneimittel zur Verbesserung kognitiver Prozesse
|
US7094768B2
(en)
*
|
2002-09-30 |
2006-08-22 |
Genelabs Technologies, Inc. |
Nucleoside derivatives for treating hepatitis C virus infection
|
AU2003279797B2
(en)
*
|
2002-09-30 |
2009-10-22 |
Genelabs Technologies, Inc. |
Nucleoside derivatives for treating hepatitis C virus infection
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
KR101026294B1
(ko)
*
|
2002-10-31 |
2011-03-31 |
메타베이시스 테라퓨틱스, 인크. |
1,3-프로판-1-아릴 디올의 신규 시클릭 포스페이트디에스테르 및 프로드럭 제조에서의 이들의 용도
|
DK1576138T3
(en)
|
2002-11-15 |
2017-05-01 |
Idenix Pharmaceuticals Llc |
2'-METHYL NUCLEOSIDES IN COMBINATION WITH INTERFERON AND FLAVIVIRIDAE MUTATION
|
US7034167B2
(en)
|
2002-12-06 |
2006-04-25 |
Merck & Co., Inc. |
Process to ribofuranose sugar derivatives as intermediates to branched-chain nucleosides
|
US7598373B2
(en)
|
2002-12-12 |
2009-10-06 |
Idenix Pharmaceuticals, Inc. |
Process for the production of 2-C-methyl-D-ribonolactone
|
US20040181051A1
(en)
*
|
2002-12-23 |
2004-09-16 |
Richard Storer |
Process for the production of 3'-nucleoside prodrugs
|
EP1594459B1
(en)
|
2002-12-30 |
2010-02-17 |
Angiotech International Ag |
Drug delivery from rapid gelling polymer composition
|
US7223785B2
(en)
|
2003-01-22 |
2007-05-29 |
Boehringer Ingelheim International Gmbh |
Viral polymerase inhibitors
|
AR043006A1
(es)
*
|
2003-02-12 |
2005-07-13 |
Merck & Co Inc |
Proceso para preparar ribonucleosidos ramificados
|
BRPI0408846A
(pt)
*
|
2003-03-28 |
2006-07-04 |
Pharmasset Inc |
compostos para o tratamento de infecções por flaviviridae
|
GB0307891D0
(en)
*
|
2003-04-04 |
2003-05-14 |
Angeletti P Ist Richerche Bio |
Chemical compounds,compositions and uses
|
US7300924B2
(en)
|
2003-04-25 |
2007-11-27 |
Gilead Sciences, Inc. |
Anti-infective phosphonate analogs
|
WO2005002626A2
(en)
*
|
2003-04-25 |
2005-01-13 |
Gilead Sciences, Inc. |
Therapeutic phosphonate compounds
|
JP2006524710A
(ja)
|
2003-04-25 |
2006-11-02 |
ギリアード サイエンシーズ, インコーポレイテッド |
キナーゼインヒビターホスホネート抱合体
|
US7407965B2
(en)
|
2003-04-25 |
2008-08-05 |
Gilead Sciences, Inc. |
Phosphonate analogs for treating metabolic diseases
|
WO2004096287A2
(en)
|
2003-04-25 |
2004-11-11 |
Gilead Sciences, Inc. |
Inosine monophosphate dehydrogenase inhibitory phosphonate compounds
|
US7452901B2
(en)
|
2003-04-25 |
2008-11-18 |
Gilead Sciences, Inc. |
Anti-cancer phosphonate analogs
|
US7432261B2
(en)
|
2003-04-25 |
2008-10-07 |
Gilead Sciences, Inc. |
Anti-inflammatory phosphonate compounds
|
NZ542342A
(en)
*
|
2003-04-25 |
2009-05-31 |
Gilead Sciences Inc |
Antiviral phosphonate analogs
|
US7470724B2
(en)
|
2003-04-25 |
2008-12-30 |
Gilead Sciences, Inc. |
Phosphonate compounds having immuno-modulatory activity
|
US20040259934A1
(en)
*
|
2003-05-01 |
2004-12-23 |
Olsen David B. |
Inhibiting Coronaviridae viral replication and treating Coronaviridae viral infection with nucleoside compounds
|
EP2345658A1
(en)
*
|
2003-05-30 |
2011-07-20 |
Pharmasset, Inc. |
Modified fluorinated nucleoside analogues
|
KR20060015742A
(ko)
|
2003-06-04 |
2006-02-20 |
제네랩스 테크놀로지스, 인코포레이티드 |
Hcv 감염의 치료를 위한 질소 함유 헤테로아릴 유도체
|
US7429596B2
(en)
*
|
2003-06-20 |
2008-09-30 |
The Regents Of The University Of California |
1H-pyrrolo [2,3-D] pyrimidine derivatives and methods of use thereof
|
US7572581B2
(en)
|
2003-06-30 |
2009-08-11 |
Roche Molecular Systems, Inc. |
2′-terminator nucleotide-related methods and systems
|
US7947817B2
(en)
|
2003-06-30 |
2011-05-24 |
Roche Molecular Systems, Inc. |
Synthesis and compositions of 2'-terminator nucleotides
|
JP2007527396A
(ja)
*
|
2003-06-30 |
2007-09-27 |
イデニクス(ケイマン)リミテツド |
β−L−2’−デオキシヌクレオシドの合成
|
PT1658302E
(pt)
*
|
2003-07-25 |
2010-10-25 |
Centre Nat Rech Scient |
Análogos do nucleósido purina para o tratamento de doenças provocadas por flaviviridae incluindo hepatite c
|
KR20060054410A
(ko)
|
2003-08-01 |
2006-05-22 |
제네랩스 테크놀로지스, 인코포레이티드 |
플라비비리다에에 대한 2고리 이미다졸 유도체
|
WO2005018330A1
(en)
*
|
2003-08-18 |
2005-03-03 |
Pharmasset, Inc. |
Dosing regimen for flaviviridae therapy
|
NZ546055A
(en)
|
2003-08-27 |
2010-05-28 |
Biota Scient Management |
Novel tricyclic nucleosides or nucleotides as therapeutic agents
|
AR045596A1
(es)
|
2003-09-05 |
2005-11-02 |
Vertex Pharma |
Inhibidores de proteasas de serina en particular proteasa ns3-ns4a del vhc
|
AU2004281780B2
(en)
|
2003-10-14 |
2009-03-19 |
F. Hoffmann-La Roche Ltd |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of HCV replication
|
US7151089B2
(en)
*
|
2003-10-27 |
2006-12-19 |
Genelabs Technologies, Inc. |
Nucleoside compounds for treating viral infections
|
AU2004286239A1
(en)
|
2003-10-24 |
2005-05-12 |
Gilead Sciences, Inc. |
Methods and compositions for identifying therapeutic compounds
|
US7427624B2
(en)
|
2003-10-24 |
2008-09-23 |
Gilead Sciences, Inc. |
Purine nucleoside phosphorylase inhibitory phosphonate compounds
|
WO2005044308A1
(en)
|
2003-10-24 |
2005-05-19 |
Gilead Sciences, Inc. |
Phosphonate analogs of antimetabolites
|
US7202223B2
(en)
*
|
2003-10-27 |
2007-04-10 |
Genelabs Technologies, Inc. |
Nucleoside compounds for treating viral infections
|
EP1687321A1
(en)
*
|
2003-10-27 |
2006-08-09 |
Genelabs Technologies, Inc. |
Nucleoside compounds for treating viral infections
|
WO2005044835A1
(en)
|
2003-10-27 |
2005-05-19 |
Genelabs Technologies, Inc. |
METHODS FOR PREPARING 7-(2'-SUBSTITUTED-ß-D-RIBOFURANOSYL)-4-(NR2R3)-5-(SUBSTITUTED ETHYN-1-YL)-PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES
|
CA2542776A1
(en)
*
|
2003-10-27 |
2005-05-12 |
Genelabs Technologies, Inc. |
Nucleoside compounds for treating viral infections
|
KR20060127906A
(ko)
|
2003-12-22 |
2006-12-13 |
길리애드 사이언시즈, 인코포레이티드 |
4'-치환된 카보버와 아바카비어 유도체 및 hiv와 hcv항바이러스 활성을 갖는 관련 화합물
|
WO2005062949A2
(en)
*
|
2003-12-23 |
2005-07-14 |
Intermune, Inc. |
Method for treating hepatitis virus infection
|
US20070258946A1
(en)
*
|
2003-12-23 |
2007-11-08 |
Blatt Lawrence M |
Combination Therapy for Treating Hepatitis C Virus Infection
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
ES2358333T3
(es)
|
2004-01-21 |
2011-05-09 |
Boehringer Ingelheim International Gmbh |
Péptidos macrocíclicos con acción contra el virus de la hepatitis c.
|
US20050182252A1
(en)
*
|
2004-02-13 |
2005-08-18 |
Reddy K. R. |
Novel 2'-C-methyl nucleoside derivatives
|
EA200901463A1
(ru)
|
2004-02-20 |
2010-08-30 |
Бёрингер Ингельхайм Интернациональ Гмбх |
Ингибиторы вирусной полимеразы
|
CN1980657A
(zh)
|
2004-05-05 |
2007-06-13 |
耶鲁大学 |
新颖的抗病毒赛菊宁黄质类似物
|
WO2005123087A2
(en)
|
2004-06-15 |
2005-12-29 |
Merck & Co., Inc. |
C-purine nucleoside analogs as inhibitors of rna-dependent rna viral polymerase
|
RU2007102281A
(ru)
*
|
2004-06-23 |
2008-07-27 |
Айденикс (Кайман) Лимитед (Ky) |
5-аза-7-деазапуриновые производные для лечения заболеваний, связанных с flaviviridae
|
US20070265222A1
(en)
*
|
2004-06-24 |
2007-11-15 |
Maccoss Malcolm |
Nucleoside Aryl Phosphoramidates for the Treatment of Rna-Dependent Rna Viral Infection
|
US7745125B2
(en)
|
2004-06-28 |
2010-06-29 |
Roche Molecular Systems, Inc. |
2′-terminator related pyrophosphorolysis activated polymerization
|
JP4283738B2
(ja)
*
|
2004-07-08 |
2009-06-24 |
浜松ホトニクス株式会社 |
半導体レーザ装置
|
NZ552927A
(en)
*
|
2004-07-21 |
2010-05-28 |
Pharmasset Inc |
Preparation of alkyl-substituted 2-deoxy-2-fluoro-D-ribofuranosyl pyrimidines and purines and their derivatives
|
CN101023094B
(zh)
*
|
2004-07-21 |
2011-05-18 |
法莫赛特股份有限公司 |
烷基取代的2-脱氧-2-氟代-d-呋喃核糖基嘧啶和嘌呤及其衍生物的制备
|
EP3539546A1
(en)
|
2004-07-27 |
2019-09-18 |
Gilead Sciences, Inc. |
Phosphonate analogs of hiv inhibitor compounds
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
JP2006077004A
(ja)
*
|
2004-08-11 |
2006-03-23 |
Chugai Pharmaceut Co Ltd |
抗hcv作用を有する化合物およびそれを含む医薬組成物
|
CN101044151B
(zh)
*
|
2004-08-23 |
2011-01-19 |
弗·哈夫曼-拉罗切有限公司 |
抗病毒的4'-叠氮基-核苷
|
RU2433124C2
(ru)
|
2004-09-14 |
2011-11-10 |
Фармассет, Инк. |
Способ получения 2'-фтор-2'-алкилзамещенных или других замещенных рибофуранозилпиримидинов и пуринов и их производных
|
AU2005291918A1
(en)
*
|
2004-10-01 |
2006-04-13 |
Vertex Pharmaceuticals Incorporated |
HCV NS3-NS4A protease inhibition
|
WO2006065335A2
(en)
*
|
2004-10-21 |
2006-06-22 |
Merck & Co., Inc. |
Fluorinated pyrrolo[2,3-d]pyrimidine nucleosides for the treatment of rna-dependent rna viral infection
|
EP1814561A4
(en)
|
2004-10-29 |
2012-12-19 |
Biocryst Pharm Inc |
THEROPUTICAL FUROPYRIMIDINES AND THIENOPYRIMIDINES
|
MY141025A
(en)
|
2004-10-29 |
2010-02-25 |
Vertex Pharma |
Dose forms
|
JP2008520744A
(ja)
|
2004-11-19 |
2008-06-19 |
ザ・レジェンツ・オブ・ザ・ユニバーシティ・オブ・カリフォルニア |
抗炎症性ピラゾロピリミジン
|
US7414031B2
(en)
*
|
2004-11-22 |
2008-08-19 |
Genelabs Technologies, Inc. |
5-nitro-nucleoside compounds for treating viral infections
|
MX2007010460A
(es)
*
|
2005-02-28 |
2007-11-08 |
Genelabs Tech Inc |
Compuestos de nucleosido triciclico para tratar infecciones virales.
|
US7524831B2
(en)
*
|
2005-03-02 |
2009-04-28 |
Schering Corporation |
Treatments for Flaviviridae virus infection
|
JP2008532950A
(ja)
|
2005-03-08 |
2008-08-21 |
バイオタ サイエンティフィック マネージメント ピーティーワイ リミテッド |
治療薬としての二環式ヌクレオシドおよび二環式ヌクレオチド
|
CA2600359A1
(en)
*
|
2005-03-09 |
2006-09-09 |
Idenix (Cayman) Limited |
Nucleosides with non-natural bases as anti-viral agents
|
US7250416B2
(en)
|
2005-03-11 |
2007-07-31 |
Supergen, Inc. |
Azacytosine analogs and derivatives
|
JP4516863B2
(ja)
*
|
2005-03-11 |
2010-08-04 |
株式会社ケンウッド |
音声合成装置、音声合成方法及びプログラム
|
WO2006101911A1
(en)
|
2005-03-16 |
2006-09-28 |
Case Western Reserve University |
Selective inhibitors of translesion dna replication
|
US9029345B2
(en)
*
|
2005-03-16 |
2015-05-12 |
Case Western Reserve University |
Selective inhibitors of translesion DNA replication
|
WO2007084157A2
(en)
*
|
2005-03-23 |
2007-07-26 |
Genelabs Technologies, Inc. |
Nucleoside prodrugs for treating viral infections
|
WO2006102594A1
(en)
*
|
2005-03-23 |
2006-09-28 |
Genelabs Technologies, Inc. |
Nucleoside prodrugs for treating viral infections
|
US7514410B2
(en)
|
2005-03-29 |
2009-04-07 |
Biocryst Pharmaceuticals, Inc. |
Hepatitis C therapies
|
US20090156545A1
(en)
*
|
2005-04-01 |
2009-06-18 |
Hostetler Karl Y |
Substituted Phosphate Esters of Nucleoside Phosphonates
|
TW200720285A
(en)
|
2005-04-25 |
2007-06-01 |
Genelabs Tech Inc |
Nucleoside compounds for treating viral infections
|
AU2006242475B2
(en)
|
2005-05-02 |
2011-07-07 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
WO2006122207A1
(en)
*
|
2005-05-10 |
2006-11-16 |
Valeant Research & Development |
6-hydrazinopurine 2'-methyl ribonucleosides and nucleotides for treatment of hcv
|
US7569600B2
(en)
|
2005-05-13 |
2009-08-04 |
Virochem Pharma Inc. |
Compounds and methods for the treatment of prevention of Flavivirus infections
|
CN100478349C
(zh)
*
|
2005-06-20 |
2009-04-15 |
河南省凯特化学实业总公司 |
氟化核苷类化合物、其制备方法及其应用
|
AR057456A1
(es)
|
2005-07-20 |
2007-12-05 |
Merck & Co Inc |
Inhibidores de la proteasa ns3 del vhc
|
MX2008001588A
(es)
*
|
2005-08-01 |
2008-02-19 |
Merck & Co Inc |
Inhibidores de proteasa ns3 del vhc.
|
US20070105781A1
(en)
*
|
2005-08-02 |
2007-05-10 |
Steve Lyons |
Inhibitors of serine proteases
|
US7964624B1
(en)
|
2005-08-26 |
2011-06-21 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases
|
AR055395A1
(es)
|
2005-08-26 |
2007-08-22 |
Vertex Pharma |
Compuestos inhibidores de la actividad de la serina proteasa ns3-ns4a del virus de la hepatitis c
|
US7700567B2
(en)
|
2005-09-29 |
2010-04-20 |
Supergen, Inc. |
Oligonucleotide analogues incorporating 5-aza-cytosine therein
|
MY150667A
(en)
|
2005-12-09 |
2014-02-28 |
Gilead Pharmasset Llc |
Antiviral nucleosides
|
ES2422290T3
(es)
|
2005-12-23 |
2013-09-10 |
Idenix Pharmaceuticals Inc |
Procedimiento para preparar un producto intermedio sintético para la preparación de nucleósidos ramificados
|
TW200800265A
(en)
*
|
2006-02-09 |
2008-01-01 |
Schering Corp |
Combinations comprising HCV protease inhibitor(s) and HCV polymerase inhibitor(s), and methods of treatment related thereto
|
CN101489557B
(zh)
|
2006-02-27 |
2013-12-18 |
弗特克斯药品有限公司 |
包含vx-950的共晶体和包含所述共晶体的药物组合物
|
EP2194039A1
(en)
|
2006-03-16 |
2010-06-09 |
Vertex Pharmceuticals Incorporated |
Process for preparing optically enriched compounds
|
MX2008012929A
(es)
|
2006-04-04 |
2008-12-17 |
Univ California |
Antagonistas de cinasa.
|
CA2647276A1
(en)
*
|
2006-04-04 |
2007-10-11 |
F. Hoffmann-La Roche Ag |
3',5'-di-o-acylated nucleosides for hcv treatment
|
BRPI0710878A2
(pt)
|
2006-04-11 |
2015-03-31 |
Novartis Ag |
Compostos orgânicos e seus usos
|
GB0609492D0
(en)
*
|
2006-05-15 |
2006-06-21 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
GB0612423D0
(en)
|
2006-06-23 |
2006-08-02 |
Angeletti P Ist Richerche Bio |
Therapeutic agents
|
US7842672B2
(en)
|
2006-07-07 |
2010-11-30 |
Gilead Sciences, Inc. |
Phosphonate inhibitors of HCV
|
WO2008073165A2
(en)
*
|
2006-08-25 |
2008-06-19 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for identifying anti-hcv agents
|
DK2084175T3
(da)
|
2006-10-10 |
2011-04-18 |
Medivir Ab |
HCV nucleosidinhibitor
|
SI2084174T1
(sl)
|
2006-10-10 |
2013-10-30 |
Gilead Pharmasset Llc |
Priprava nukleozidov ribofuranozil pririmidinov
|
US8138164B2
(en)
*
|
2006-10-24 |
2012-03-20 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
WO2008051477A2
(en)
*
|
2006-10-24 |
2008-05-02 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
EP2079480B1
(en)
*
|
2006-10-24 |
2013-06-05 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
CN101568346B
(zh)
|
2006-10-27 |
2015-11-25 |
默沙东公司 |
Hcv ns3蛋白酶抑制剂
|
RU2468029C2
(ru)
|
2006-10-27 |
2012-11-27 |
Иституто Ди Ричерке Ди Биолоджиа Молеколаре П.Анджелетти С.П.А. |
Ингибиторы hcv ns3 протеазы
|
BRPI0718714B8
(pt)
|
2006-11-09 |
2021-05-25 |
Hoffmann La Roche |
arilamidas substituídas por tiazol e oxazol, seu uso e composição farmacêutica que as compreende
|
EP2559692A1
(en)
|
2006-11-15 |
2013-02-20 |
Virochem Pharma Inc. |
Thiophene analogues for the treatment or prevention of Flavivirus infections
|
GB0623493D0
(en)
|
2006-11-24 |
2007-01-03 |
Univ Cardiff |
Chemical compounds
|
GB0625345D0
(en)
*
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
GB0625349D0
(en)
|
2006-12-20 |
2007-01-31 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
CA2672250C
(en)
*
|
2006-12-20 |
2013-04-30 |
Ian Stansfield |
Antiviral indoles
|
US20080261913A1
(en)
|
2006-12-28 |
2008-10-23 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of liver disorders
|
CA2673649A1
(en)
|
2007-01-05 |
2008-07-17 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Nucleoside aryl phosphoramidates for the treatment of rna-dependent rna viral infection
|
TW200838550A
(en)
*
|
2007-02-09 |
2008-10-01 |
Novartis Ag |
Organic compounds
|
KR20090115970A
(ko)
|
2007-02-27 |
2009-11-10 |
버텍스 파마슈티칼스 인코포레이티드 |
공-결정 및 그를 포함하는 제약 조성물
|
CA2679426A1
(en)
|
2007-02-27 |
2008-09-04 |
Luc Farmer |
Inhibitors of serine proteases
|
JP2010520200A
(ja)
*
|
2007-02-28 |
2010-06-10 |
クオナトウス ファーマシューティカルズ,インコーポレイテッド |
特定のマトリックスメタロプロテイナーゼ(mmp)阻害剤を使用する肝疾患を治療する方法
|
WO2008106167A1
(en)
*
|
2007-02-28 |
2008-09-04 |
Conatus Pharmaceuticals, Inc. |
Combination therapy comprising matrix metalloproteinase inhibitors and caspase inhibitors for the treatment of liver diseases
|
US20100129437A1
(en)
|
2007-03-23 |
2010-05-27 |
Bbb Holding B.V. |
Targeted intracellular delivery of antiviral agents
|
US7964580B2
(en)
|
2007-03-30 |
2011-06-21 |
Pharmasset, Inc. |
Nucleoside phosphoramidate prodrugs
|
ES2393038T3
(es)
*
|
2007-05-10 |
2012-12-18 |
Biocryst Pharmaceuticals, Inc. |
Compuestos de tretrahidrofuro[3,4-D]dioxolano para su utlilización en el tratamiento de las infecciones víricas y del cáncer
|
GB0709791D0
(en)
*
|
2007-05-22 |
2007-06-27 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
WO2009005615A1
(en)
*
|
2007-06-27 |
2009-01-08 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for identifying agents that inhibit an ns4b-mediated neoplastic cellular phenotype of hcv infected cells
|
CN100532388C
(zh)
*
|
2007-07-16 |
2009-08-26 |
郑州大学 |
2’-氟-4’-取代-核苷类似物、其制备方法及应用
|
WO2009010783A1
(en)
|
2007-07-17 |
2009-01-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Macrocyclic indole derivatives for the treatment of hepatitis c infections
|
AU2008277377B2
(en)
|
2007-07-19 |
2013-08-01 |
Msd Italia S.R.L. |
Macrocyclic compounds as antiviral agents
|
US8492546B2
(en)
|
2007-08-30 |
2013-07-23 |
Vertex Pharmaceuticals Incorporated |
Co-crystals and pharmaceutical compositions comprising the same
|
GB0718575D0
(en)
|
2007-09-24 |
2007-10-31 |
Angeletti P Ist Richerche Bio |
Nucleoside derivatives as inhibitors of viral polymerases
|
US20110160232A1
(en)
*
|
2007-10-04 |
2011-06-30 |
Pingda Ren |
Certain chemical entities and therapeutic uses thereof
|
US20090318380A1
(en)
|
2007-11-20 |
2009-12-24 |
Pharmasset, Inc. |
2',4'-substituted nucleosides as antiviral agents
|
EP2217602B1
(en)
|
2007-11-30 |
2018-08-29 |
Boehringer Ingelheim International GmbH |
1,5-dihydro-pyrazolo[3,4-d]pyrimidin-4-one derivatives and their use as pde9a modulators for the treatment of cns disorders
|
ES2570628T3
(es)
|
2007-12-17 |
2016-05-19 |
Hoffmann La Roche |
Nuevas arilamidas con sustitución imidazol
|
DK2234976T3
(da)
|
2007-12-17 |
2013-06-24 |
Hoffmann La Roche |
Nye pyrazol-substituerede arylamider
|
JP5456691B2
(ja)
|
2007-12-17 |
2014-04-02 |
エフ.ホフマン−ラ ロシュ アーゲー |
テトラゾール置換されたアリールアミド誘導体ならびにp2x3及び/又はp2x2/3プリン作動性受容体アンタゴニストとしてのその使用
|
AU2008337660B2
(en)
|
2007-12-17 |
2014-02-06 |
F. Hoffmann-La Roche Ag |
Triazole-substituted arylamide derivatives and their use as P2X3 and /or P2X2/3 purinergic receptor antagonists
|
SG187425A1
(en)
|
2008-01-04 |
2013-02-28 |
Intellikine Llc |
Certain chemical entities, compositions and methods
|
US8193182B2
(en)
|
2008-01-04 |
2012-06-05 |
Intellikine, Inc. |
Substituted isoquinolin-1(2H)-ones, and methods of use thereof
|
WO2009114874A2
(en)
|
2008-03-14 |
2009-09-17 |
Intellikine, Inc. |
Benzothiazole kinase inhibitors and methods of use
|
JP5547099B2
(ja)
|
2008-03-14 |
2014-07-09 |
インテリカイン, エルエルシー |
キナーゼ阻害剤および使用方法
|
US8227431B2
(en)
*
|
2008-03-17 |
2012-07-24 |
Hetero Drugs Limited |
Nucleoside derivatives
|
TW200946541A
(en)
|
2008-03-27 |
2009-11-16 |
Idenix Pharmaceuticals Inc |
Solid forms of an anti-HIV phosphoindole compound
|
UA105362C2
(en)
|
2008-04-02 |
2014-05-12 |
Бьорингер Ингельхайм Интернациональ Гмбх |
1-heterocyclyl-1, 5-dihydro-pyrazolo [3, 4-d] pyrimidin-4-one derivatives and their use as pde9a modulators
|
US8415321B2
(en)
*
|
2008-04-15 |
2013-04-09 |
Raymond F. Schinazi |
Nucleoside derivatives for treatment of Caliciviridae infections, including Norovirus infections
|
EA020659B1
(ru)
*
|
2008-04-23 |
2014-12-30 |
Джилид Сайэнс, Инк. |
1'-замещённые карбануклеозидные аналоги для противовирусной терапии
|
AU2013216595B2
(en)
*
|
2008-04-23 |
2016-07-28 |
Gilead Sciences, Inc. |
1' -substituted carba-nucleoside analogs for antiviral treatment
|
US8461107B2
(en)
*
|
2008-04-28 |
2013-06-11 |
Merck Sharp & Dohme Corp. |
HCV NS3 protease inhibitors
|
CN102083852A
(zh)
|
2008-06-06 |
2011-06-01 |
西尼克斯公司 |
环孢菌素类似物及其在治疗hcv感染中的应用
|
US8173621B2
(en)
|
2008-06-11 |
2012-05-08 |
Gilead Pharmasset Llc |
Nucleoside cyclicphosphates
|
US20110053226A1
(en)
*
|
2008-06-13 |
2011-03-03 |
Riboxx Gmbh |
Method for enzymatic synthesis of chemically modified rna
|
CA2729168A1
(en)
|
2008-07-02 |
2010-02-04 |
Idenix Pharmaceuticals, Inc. |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
EP2313102A2
(en)
|
2008-07-03 |
2011-04-27 |
Biota Scientific Management |
Bycyclic nucleosides and nucleotides as therapeutic agents
|
JP5788316B2
(ja)
|
2008-07-08 |
2015-09-30 |
インテリカイン, エルエルシー |
キナーゼインヒビターおよび使用方法
|
WO2010006072A2
(en)
*
|
2008-07-08 |
2010-01-14 |
The Regents Of The University Of California |
Mtor modulators and uses thereof
|
AU2009268681B2
(en)
|
2008-07-08 |
2014-10-02 |
Gilead Sciences, Inc. |
Salts of HIV inhibitor compounds
|
BRPI0916235B8
(pt)
|
2008-07-22 |
2021-05-25 |
Merck Sharp & Dohme |
composto, composição farmacêutica, e, uso do composto ou da composição
|
JP4621926B2
(ja)
*
|
2008-07-24 |
2011-02-02 |
国立大学法人九州大学 |
酵素基質修飾ヌクレオシド三リン酸、核酸プローブ、マルチラベル化核酸プローブ、マルチラベル化核酸プローブの製造方法および標的核酸の検出方法
|
JP5146785B2
(ja)
*
|
2008-07-24 |
2013-02-20 |
国立大学法人九州大学 |
酵素基質修飾ヌクレオシド三リン酸誘導体
|
WO2010015637A1
(en)
*
|
2008-08-06 |
2010-02-11 |
Novartis Ag |
New antiviral modified nucleosides
|
UA103195C2
(uk)
|
2008-08-11 |
2013-09-25 |
Глаксосмитклайн Ллк |
Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань
|
HUE033645T2
(en)
|
2008-08-11 |
2017-12-28 |
Glaxosmithkline Llc |
New adenine derivatives
|
JP2011530562A
(ja)
|
2008-08-11 |
2011-12-22 |
グラクソスミスクライン エルエルシー |
アレルギー性、炎症性及び感染性疾患治療用のプリン誘導体
|
CA2736304A1
(en)
|
2008-09-08 |
2010-03-11 |
Boehringer Ingelheim International Gmbh |
Pyrazolopyrimidines and their use for the treatment of cns disorders
|
US8703778B2
(en)
|
2008-09-26 |
2014-04-22 |
Intellikine Llc |
Heterocyclic kinase inhibitors
|
EP2341924A4
(en)
|
2008-10-02 |
2013-01-23 |
David Gladstone Inst |
METHOD FOR THE TREATMENT OF HEPATITIS C VIRUS INFECTIONS
|
CA2740885C
(en)
|
2008-10-16 |
2018-04-03 |
The Regents Of The University Of California |
Fused ring heteroaryl kinase inhibitors
|
US8476431B2
(en)
*
|
2008-11-03 |
2013-07-02 |
Itellikine LLC |
Benzoxazole kinase inhibitors and methods of use
|
JP5645840B2
(ja)
|
2008-12-02 |
2014-12-24 |
株式会社Wave Life Sciences Japan |
リン原子修飾核酸の合成方法
|
PA8855801A1
(es)
|
2008-12-23 |
2010-07-27 |
|
Sintesis de nucleosidos de purina
|
AR074897A1
(es)
|
2008-12-23 |
2011-02-23 |
Pharmasset Inc |
Fosforamidatos de nucleosidos
|
EP2376514A2
(en)
|
2008-12-23 |
2011-10-19 |
Pharmasset, Inc. |
Nucleoside analogs
|
WO2010082050A1
(en)
|
2009-01-16 |
2010-07-22 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
|
GB0900914D0
(en)
|
2009-01-20 |
2009-03-04 |
Angeletti P Ist Richerche Bio |
Antiviral agents
|
PE20120020A1
(es)
*
|
2009-01-21 |
2012-02-02 |
Hoffmann La Roche |
Composicion farmaceutica que comprende un profarmaco inhibidor de la polimerasa de vhc
|
UA112140C2
(uk)
|
2009-02-10 |
2016-07-25 |
Гіліад Сайєнсіз, Інк. |
Нуклеозидні похідіні (варіанти), фармацевтична композиція на їх основі, спосіб лікування вірусної інфекції та застосування сполуки для виробництва лікарського засобу
|
JP2012517478A
(ja)
|
2009-02-12 |
2012-08-02 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
ペグ化インターフェロン、リバビリンおよびテラプレビルを含む、hcv組合せ治療剤
|
US8193372B2
(en)
|
2009-03-04 |
2012-06-05 |
Idenix Pharmaceuticals, Inc. |
Phosphothiophene and phosphothiazole HCV polymerase inhibitors
|
JP2012520884A
(ja)
|
2009-03-18 |
2012-09-10 |
ザ ボード オブ トラスティーズ オブ ザ リランド スタンフォード ジュニア ユニバーシティー |
フラビウイルス科ウイルス感染症を治療する方法および組成物
|
WO2010108140A1
(en)
*
|
2009-03-20 |
2010-09-23 |
Alios Biopharma, Inc. |
Substituted nucleoside and nucleotide analogs
|
MX2011010184A
(es)
|
2009-03-31 |
2011-10-28 |
Boehringer Ingelheim Int |
Derivados de 1-heterociclil-1,5-dihidro-pirazolo[3,4-d]pirimidin-4 -ona y su uso como moduladores de pde9a.
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
SI2421879T1
(sl)
*
|
2009-04-22 |
2014-01-31 |
Institute Of Organic Chemistry And Biochemistry As Cr |
Novi 7-deazapurinski nukleozidi za terapevtske uporabe
|
WO2010129816A2
(en)
|
2009-05-07 |
2010-11-11 |
Intellikine, Inc. |
Heterocyclic compounds and uses thereof
|
JO3027B1
(ar)
*
|
2009-05-14 |
2016-09-05 |
Janssen Products Lp |
نيوكليوسيدات يوراسيل سبيرواوكسيتان
|
WO2010135520A1
(en)
*
|
2009-05-20 |
2010-11-25 |
Chimerix, Inc. |
Compounds, compositions and methods for treating viral infection
|
US8618076B2
(en)
|
2009-05-20 |
2013-12-31 |
Gilead Pharmasset Llc |
Nucleoside phosphoramidates
|
TWI583692B
(zh)
|
2009-05-20 |
2017-05-21 |
基利法瑪席特有限責任公司 |
核苷磷醯胺
|
EP2445897B1
(en)
|
2009-06-22 |
2014-03-19 |
F.Hoffmann-La Roche Ag |
Novel indazole arylamides as p2x3 and/or p2x2/3 antagonists
|
ES2450891T3
(es)
|
2009-06-22 |
2014-03-25 |
F. Hoffmann-La Roche Ag |
Bifenilamidas útiles como moduladores de receptores P2X3 y/o P2X2/3
|
SG176640A1
(en)
|
2009-06-22 |
2012-01-30 |
Hoffmann La Roche |
Novel oxazolone and pyrrolidinone-substituted arylamides
|
JP5998326B2
(ja)
|
2009-07-06 |
2016-09-28 |
ウェイブ ライフ サイエンス リミテッドWave Life Sciences Ltd. |
新規核酸プロドラッグおよびその使用方法
|
WO2011014487A1
(en)
|
2009-07-30 |
2011-02-03 |
Merck Sharp & Dohme Corp. |
Hepatitis c virus ns3 protease inhibitors
|
EP2461811B1
(en)
|
2009-08-05 |
2016-04-20 |
Idenix Pharmaceuticals LLC. |
Macrocyclic serine protease inhibitors useful against viral infections, particularly hcv
|
AR077859A1
(es)
|
2009-08-12 |
2011-09-28 |
Boehringer Ingelheim Int |
Compuestos para el tratamiento de trastornos del snc
|
US8796394B2
(en)
*
|
2009-08-27 |
2014-08-05 |
Northwestern University |
Antifouling hydrogels, coatings, and methods of synthesis and use thereof
|
US8455451B2
(en)
*
|
2009-09-21 |
2013-06-04 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
US7973013B2
(en)
|
2009-09-21 |
2011-07-05 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
CA2773772C
(en)
*
|
2009-09-21 |
2018-06-26 |
Gilead Sciences, Inc. |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
MX2012003126A
(es)
|
2009-09-21 |
2012-06-19 |
Gilead Sciences Inc |
Procesos e intermedios para la preparacion de analogos de 1'-carbonucleosidos sustituidos.
|
WO2011047384A2
(en)
|
2009-10-16 |
2011-04-21 |
The Regents Of The University Of California |
Methods of inhibiting ire1
|
US20120220581A1
(en)
|
2009-10-30 |
2012-08-30 |
Janssen-Cilag, S.A. |
IMIDAZO[1,2-b]PYRIDAZINE DERIVATIVES AND THEIR USE AS PDE10 INHIBITORS
|
CA2780044A1
(en)
|
2009-11-14 |
2011-05-19 |
F. Hoffmann-La Roche Ag |
Biomarkers for predicting rapid response to hcv treatment
|
WO2011060408A2
(en)
*
|
2009-11-16 |
2011-05-19 |
University Of Georgia Research Foundation, Inc. |
2'-fluoro-6'-methylene carbocyclic nucleosides and methods of treating viral infections
|
US20110117055A1
(en)
|
2009-11-19 |
2011-05-19 |
Macdonald James E |
Methods of Treating Hepatitis C Virus with Oxoacetamide Compounds
|
CA2781614A1
(en)
|
2009-11-25 |
2011-06-09 |
Vertex Pharmaceuticals Incorporated |
5-alkynyl-thiophene-2-carboxylic acid derivatives and their use for the treatment or prevention of flavivirus infections
|
RU2012127201A
(ru)
|
2009-12-02 |
2014-01-20 |
Ф.Хоффманн-Ля Рош Аг |
Биомаркеры для прогнозирования устойчивого ответа на лечение вируса гепатита с
|
EP2513113B1
(en)
|
2009-12-18 |
2018-08-01 |
Idenix Pharmaceuticals LLC |
5,5-fused arylene or heteroarylene hepatitis c virus inhibitors
|
AU2010336355A1
(en)
|
2009-12-24 |
2012-07-05 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
JP5704481B2
(ja)
*
|
2010-01-22 |
2015-04-22 |
国立大学法人九州大学 |
核酸検出用キット
|
RU2556991C2
(ru)
*
|
2010-01-28 |
2015-07-20 |
Рибосайенс Ллк |
4'-азидонуклеозиды, активные в отношении hcv
|
KR20120139699A
(ko)
|
2010-01-29 |
2012-12-27 |
버텍스 파마슈티칼스 인코포레이티드 |
C형 간염 바이러스 감염의 치료 요법
|
US8703754B2
(en)
|
2010-02-10 |
2014-04-22 |
Glaxosmithkline Llc |
6-amino-2-{[(1S)-1-methylbutyl]oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8H-purin-8-one maleate
|
WO2011098451A1
(en)
|
2010-02-10 |
2011-08-18 |
Glaxosmithkline Llc |
Purine derivatives and their pharmaceutical uses
|
AR080754A1
(es)
|
2010-03-09 |
2012-05-09 |
Janssen Pharmaceutica Nv |
Derivados de imidazo (1,2-a) pirazina y su uso como inhibidores de pde10
|
CN102869657A
(zh)
|
2010-03-24 |
2013-01-09 |
沃泰克斯药物股份有限公司 |
用于治疗或预防黄病毒感染的类似物
|
EP2550262A1
(en)
|
2010-03-24 |
2013-01-30 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of flavivirus infections
|
TW201141857A
(en)
|
2010-03-24 |
2011-12-01 |
Vertex Pharma |
Analogues for the treatment or prevention of flavivirus infections
|
AU2011232348A1
(en)
|
2010-03-24 |
2012-10-11 |
Vertex Pharmaceuticals Incorporated |
Analogues for the treatment or prevention of Flavivirus infections
|
UY33312A
(es)
|
2010-03-31 |
2011-10-31 |
Pharmasset Inc |
Fosforamidato de nucleosido de purina
|
US8859756B2
(en)
|
2010-03-31 |
2014-10-14 |
Gilead Pharmasset Llc |
Stereoselective synthesis of phosphorus containing actives
|
PL3290428T3
(pl)
|
2010-03-31 |
2022-02-07 |
Gilead Pharmasset Llc |
Tabletka zawierająca krystaliczny (S)-2-(((S)-(((2R,3R,4R,5R)-5-(2,4-diokso-3,4-dihydropirymidyn-1(2H)-ylo)-4-fluoro-3-hydroksy-4-metylotetrahydrofuran-2-ylo)metoksy)(fenoksy)fosforylo)amino)propanian izopropylu
|
MX2012011222A
(es)
|
2010-04-01 |
2013-01-18 |
Centre Nat Rech Scient |
Compuestos y composiciones farmaceuticas para el tratamiento de infecciones virales.
|
CA2799579A1
(en)
|
2010-05-21 |
2011-11-24 |
Intellikine, Inc. |
Chemical compounds, compositions and methods for kinase modulation
|
TW201201815A
(en)
|
2010-05-28 |
2012-01-16 |
Gilead Sciences Inc |
1'-substituted-carba-nucleoside prodrugs for antiviral treatment
|
WO2011156545A1
(en)
|
2010-06-09 |
2011-12-15 |
Vertex Pharmaceuticals Incorporated |
Viral dynamic model for hcv combination therapy
|
EP2582717A2
(en)
|
2010-06-15 |
2013-04-24 |
Vertex Pharmaceuticals Incorporated |
Hcv ns5b polymerase mutants
|
JP2013531011A
(ja)
|
2010-06-28 |
2013-08-01 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
フラビウイルス感染の処置または予防のための化合物および方法
|
MX2012014918A
(es)
|
2010-06-28 |
2013-04-08 |
Vertex Pharma |
Compuestos y metodos para tratamiento o prevencion de infecciones por flavivirus.
|
WO2012006070A1
(en)
|
2010-06-28 |
2012-01-12 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flavivirus infections
|
TW201208704A
(en)
|
2010-07-14 |
2012-03-01 |
Vertex Pharma |
Palatable pharmaceutical composition
|
AP2013006665A0
(en)
|
2010-07-19 |
2013-01-31 |
Gilead Sciences Inc |
Methods for the preparation of diasteromerically pure phosphoramidate prodrugs
|
MX2013000744A
(es)
|
2010-07-22 |
2013-03-07 |
Gilead Sciences Inc |
Metodos y compuestos para tratar infecciones virales por paramyxoviridae.
|
MY170189A
(en)
|
2010-08-12 |
2019-07-09 |
Boehringer Ingelheim Int |
6-cycloalkyl-1, 5-dihydro-pyrazolo[3,4-d] pyrimidin-4-one derivatives and their use as pde9a inhibitors
|
CA2808291A1
(en)
|
2010-08-17 |
2012-02-23 |
Vertex Pharmaceuticals Incorporated |
Compounds and methods for the treatment or prevention of flaviviridae viral infections
|
AP3699A
(en)
*
|
2010-09-20 |
2016-05-31 |
Gilead Sciences Inc |
2'-fluoro substituted carba-nucleoside analogs for antiviral treatment
|
MX2013003153A
(es)
|
2010-09-22 |
2013-05-01 |
Alios Biopharma Inc |
Analogos de nucleotidos sustituidos.
|
US8877731B2
(en)
|
2010-09-22 |
2014-11-04 |
Alios Biopharma, Inc. |
Azido nucleosides and nucleotide analogs
|
DK2620428T3
(da)
|
2010-09-24 |
2019-07-01 |
Wave Life Sciences Ltd |
Asymmetrisk hjælpegruppe
|
WO2012048235A1
(en)
|
2010-10-08 |
2012-04-12 |
Novartis Ag |
Vitamin e formulations of sulfamide ns3 inhibitors
|
CN103298474B
(zh)
|
2010-11-10 |
2016-06-29 |
无限药品股份有限公司 |
杂环化合物及其用途
|
ES2716158T3
(es)
|
2010-11-30 |
2019-06-10 |
Gilead Pharmasset Llc |
2'-spiro-nucleótidos para el tratamiento de hepatitis C
|
WO2012080050A1
(en)
|
2010-12-14 |
2012-06-21 |
F. Hoffmann-La Roche Ag |
Solid forms of a phenoxybenzenesulfonyl compound
|
EP2655392B1
(en)
|
2010-12-22 |
2018-04-18 |
Alios Biopharma, Inc. |
Cyclic nucleotide analogs
|
ES2637113T3
(es)
|
2011-01-10 |
2017-10-10 |
Infinity Pharmaceuticals, Inc. |
Procedimientos para preparar isoquinolinonas y formas sólidas de isoquinolinonas
|
WO2012109398A1
(en)
|
2011-02-10 |
2012-08-16 |
Idenix Pharmaceuticals, Inc. |
Macrocyclic serine protease inhibitors, pharmaceutical compositions thereof, and their use for treating hcv infections
|
WO2012109646A1
(en)
|
2011-02-11 |
2012-08-16 |
Vertex Pharmaceuticals Incorporated |
Treatment of hcv in hiv infection patients
|
US20130040971A1
(en)
|
2011-02-14 |
2013-02-14 |
Boehringer Ingelheim International Gmbh |
6-cycloalkyl-pyrazolopyrimidinones for the treatment of cns disorders
|
US8809345B2
(en)
|
2011-02-15 |
2014-08-19 |
Boehringer Ingelheim International Gmbh |
6-cycloalkyl-pyrazolopyrimidinones for the treatment of CNS disorders
|
JP6130305B2
(ja)
|
2011-02-23 |
2017-05-17 |
インテリカイン, エルエルシー |
キナーゼ阻害剤の組み合わせおよびそれらの使用
|
US20120252721A1
(en)
|
2011-03-31 |
2012-10-04 |
Idenix Pharmaceuticals, Inc. |
Methods for treating drug-resistant hepatitis c virus infection with a 5,5-fused arylene or heteroarylene hepatitis c virus inhibitor
|
US9243025B2
(en)
|
2011-03-31 |
2016-01-26 |
Idenix Pharmaceuticals, Llc |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
PE20140522A1
(es)
|
2011-04-13 |
2014-05-03 |
Merck Sharp & Dohme |
Derivados de nucleosidos 2'- sustituidos y metodos de uso de los mismos para el tratamiento de enfermedades virales
|
EP2696679B1
(en)
|
2011-04-13 |
2017-08-02 |
Merck Sharp & Dohme Corp. |
2'-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
EA201391264A1
(ru)
|
2011-04-13 |
2014-03-31 |
Джилид Сайэнс, Инк. |
1'-замещенные пиримидиновые n-нуклеозидные аналоги для противовирусного лечения
|
US9156872B2
(en)
|
2011-04-13 |
2015-10-13 |
Merck Sharp & Dohme Corp. |
2′-azido substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
WO2013000924A1
(en)
|
2011-06-27 |
2013-01-03 |
Janssen Pharmaceutica Nv |
1-ARYL-4-METHYL-[1,2,4]TRIAZOLO[4,3-a]QUINOXALINE DERIVATIVES
|
WO2013009735A1
(en)
|
2011-07-13 |
2013-01-17 |
Merck Sharp & Dohme Corp. |
5'-substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
EP2731433A4
(en)
|
2011-07-13 |
2014-12-31 |
Merck Sharp & Dohme |
5'-SUBSTITUTED NUCLEOSIDE ANALOGUES AND METHODS OF USE FOR THE TREATMENT OF VIRAL DISEASES
|
US8969363B2
(en)
|
2011-07-19 |
2015-03-03 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
CA2842190A1
(en)
|
2011-07-19 |
2013-01-24 |
Infinity Pharmaceuticals Inc. |
Heterocyclic compounds and uses thereof
|
MX347361B
(es)
|
2011-07-19 |
2017-04-12 |
Wave Life Sciences Ltd |
Metodos para la sintesis de acidos nucleicos funcionalizados.
|
WO2013016499A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Methods for preparation of thiophene compounds
|
WO2013016501A1
(en)
|
2011-07-26 |
2013-01-31 |
Vertex Pharmaceuticals Incorporated |
Formulations of thiophene compounds
|
RU2014111823A
(ru)
|
2011-08-29 |
2015-10-10 |
Инфинити Фармасьютикалз, Инк. |
Гетероциклические соединения и их применения
|
ES2702495T3
(es)
|
2011-08-30 |
2019-03-01 |
Astex Pharmaceuticals Inc |
Formulaciones de derivados de decitabina
|
WO2013033705A2
(en)
|
2011-09-01 |
2013-03-07 |
Case Western Reserve University |
Non-natural nucleosides as theranostic agents
|
JP6342805B2
(ja)
|
2011-09-02 |
2018-06-13 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
置換ピラゾロ[3,4−d]ピリミジンおよびその用途
|
EP2755985B1
(en)
|
2011-09-12 |
2017-11-01 |
Idenix Pharmaceuticals LLC |
Compounds and pharmaceutical compositions for the treatment of viral infections
|
EP2755983B1
(en)
|
2011-09-12 |
2017-03-15 |
Idenix Pharmaceuticals LLC. |
Substituted carbonyloxymethylphosphoramidate compounds and pharmaceutical compositions for the treatment of viral infections
|
KR101991298B1
(ko)
|
2011-09-16 |
2019-06-21 |
길리애드 파마셋 엘엘씨 |
Hcv 치료 방법
|
WO2013056046A1
(en)
|
2011-10-14 |
2013-04-18 |
Idenix Pharmaceuticals, Inc. |
Substituted 3',5'-cyclic phosphates of purine nucleotide compounds and pharmaceutical compositions for the treatment of viral infections
|
US8466159B2
(en)
|
2011-10-21 |
2013-06-18 |
Abbvie Inc. |
Methods for treating HCV
|
US8492386B2
(en)
|
2011-10-21 |
2013-07-23 |
Abbvie Inc. |
Methods for treating HCV
|
CN104023726A
(zh)
|
2011-10-21 |
2014-09-03 |
艾伯维公司 |
用于治疗hcv的一种或多种daa的联合治疗(例如,与abt-072或abt-333)
|
US8853176B2
(en)
|
2011-10-21 |
2014-10-07 |
Abbvie Inc. |
Methods for treating HCV
|
WO2013070887A1
(en)
*
|
2011-11-10 |
2013-05-16 |
Inhibitex, Inc. |
Substituted purine nucleosides, phosphoramidate and phosphordiamidate derivatives for treatment of viral infections
|
EP2780026B1
(en)
|
2011-11-15 |
2019-10-23 |
Merck Sharp & Dohme Corp. |
Hcv ns3 protease inhibitors
|
US8889159B2
(en)
|
2011-11-29 |
2014-11-18 |
Gilead Pharmasset Llc |
Compositions and methods for treating hepatitis C virus
|
CN104185420B
(zh)
|
2011-11-30 |
2017-06-09 |
埃默里大学 |
用于治疗或预防逆转录病毒和其它病毒感染的抗病毒jak抑制剂
|
WO2013084165A1
(en)
*
|
2011-12-05 |
2013-06-13 |
Medivir Ab |
Hcv polymerase inhibitors
|
AU2012347785B2
(en)
|
2011-12-06 |
2017-03-16 |
The Board Of Trustees Of The Leland Stanford Junior University |
Methods and compositions for treating viral diseases
|
AP2014007796A0
(en)
|
2011-12-22 |
2014-07-31 |
Alios Biopharma Inc |
Substituted nucleosides, nucleotides and analogs thereof
|
US8980865B2
(en)
|
2011-12-22 |
2015-03-17 |
Alios Biopharma, Inc. |
Substituted nucleotide analogs
|
US20140356325A1
(en)
|
2012-01-12 |
2014-12-04 |
Ligand Pharmaceuticals Incorporated |
Novel 2'-c-methyl nucleoside derivative compounds
|
WO2013116339A1
(en)
|
2012-01-31 |
2013-08-08 |
Vertex Pharmaceuticals Incorporated |
High potency formulations of vx-950
|
US20130217644A1
(en)
|
2012-02-13 |
2013-08-22 |
Idenix Pharmaceuticals, Inc. |
Pharmaceutical Compositions of 2'-C-Methyl-Guanosine, 5'-[2[(3-Hydroxy-2,2-Dimethyl-1-Oxopropyl)Thio]Ethyl N-(Phenylmethyl)Phosphoramidate]
|
MX2014009850A
(es)
|
2012-02-14 |
2015-03-10 |
Univ Georgia |
Spiro [2.4] heptanos para aplicaciones relacionadas con el tratamiento de infecciones de flaviviridae.
|
EP3210993B1
(en)
*
|
2012-03-13 |
2018-12-12 |
Gilead Sciences, Inc. |
2'- substituted carba-nucleoside analogs for antiviral treatment
|
USRE48171E1
(en)
|
2012-03-21 |
2020-08-25 |
Janssen Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
WO2013142124A1
(en)
|
2012-03-21 |
2013-09-26 |
Vertex Pharmaceuticals Incorporated |
Solid forms of a thiophosphoramidate nucleotide prodrug
|
US9441007B2
(en)
|
2012-03-21 |
2016-09-13 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
EA035159B1
(ru)
|
2012-03-21 |
2020-05-06 |
Янссен Байофарма, Инк. |
Замещенные нуклеозиды, нуклеотиды и их аналоги
|
US9012427B2
(en)
|
2012-03-22 |
2015-04-21 |
Alios Biopharma, Inc. |
Pharmaceutical combinations comprising a thionucleotide analog
|
US8940742B2
(en)
|
2012-04-10 |
2015-01-27 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
WO2013177188A1
(en)
|
2012-05-22 |
2013-11-28 |
Idenix Pharmaceuticals, Inc. |
3',5'-cyclic phosphoramidate prodrugs for hcv infection
|
AP3913A
(en)
|
2012-05-22 |
2016-11-26 |
Idenix Pharamaceuticals Inc |
D-amino acid compounds for liver disease
|
US9296778B2
(en)
|
2012-05-22 |
2016-03-29 |
Idenix Pharmaceuticals, Inc. |
3′,5′-cyclic phosphate prodrugs for HCV infection
|
EP2861611B1
(en)
|
2012-05-25 |
2016-07-13 |
Janssen Sciences Ireland UC |
Uracyl spirooxetane nucleosides
|
US9206412B2
(en)
*
|
2012-05-31 |
2015-12-08 |
Colorado State University Research Foundation |
Thioxothiazolidine inhibitors
|
US8828998B2
(en)
|
2012-06-25 |
2014-09-09 |
Infinity Pharmaceuticals, Inc. |
Treatment of lupus, fibrotic conditions, and inflammatory myopathies and other disorders using PI3 kinase inhibitors
|
CA2872216C
(en)
|
2012-06-26 |
2021-07-20 |
Janssen Pharmaceutica Nv |
Combinations comprising pde 2 inhibitors such as 1-aryl-4-methyl-[1,2,4] triazolo [4,3-a] quinoxaline compounds and pde 10 inhibitors for use in the treatment of neurological or metabolic disorders
|
JP6174695B2
(ja)
|
2012-07-09 |
2017-08-02 |
ヤンセン ファーマシューティカ エヌ.ベー. |
ホスホジエステラーゼ10酵素の阻害剤
|
WO2014010718A1
(ja)
|
2012-07-13 |
2014-01-16 |
株式会社新日本科学 |
キラル核酸アジュバント
|
KR102213609B1
(ko)
|
2012-07-13 |
2021-02-08 |
웨이브 라이프 사이언시스 리미티드 |
키랄 제어
|
DK2872485T3
(da)
|
2012-07-13 |
2021-03-08 |
Wave Life Sciences Ltd |
Asymmetrisk hjælpegruppe
|
US9556216B2
(en)
|
2012-08-31 |
2017-01-31 |
Novartis Ag |
2′-Ethynyl nucleoside derivatives for treatment of viral infections
|
CN104995192A
(zh)
|
2012-09-26 |
2015-10-21 |
加利福尼亚大学董事会 |
Ire1的调节
|
WO2014052638A1
(en)
|
2012-09-27 |
2014-04-03 |
Idenix Pharmaceuticals, Inc. |
Esters and malonates of sate prodrugs
|
EA030189B8
(ru)
|
2012-10-08 |
2018-10-31 |
Иденикс Фармасьютикалз Ллс |
Аналоги 2'-хлоронуклеозидов для инфекции вгс
|
US9457039B2
(en)
|
2012-10-17 |
2016-10-04 |
Merck Sharp & Dohme Corp. |
2′-disubstituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
US9242988B2
(en)
|
2012-10-17 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
2′-cyano substituted nucleoside derivatives and methods of use thereof for the treatment of viral diseases
|
AR092959A1
(es)
|
2012-10-17 |
2015-05-06 |
Merck Sharp & Dohme |
Derivados de nucleosidos 2-metil sustituidos y metodos de uso de los mismos para el tratamiento de enfermedades virales
|
EP2909223B1
(en)
|
2012-10-19 |
2017-03-22 |
Idenix Pharmaceuticals LLC |
Dinucleotide compounds for hcv infection
|
US10723754B2
(en)
|
2012-10-22 |
2020-07-28 |
Idenix Pharmaceuticals Llc |
2′,4′-bridged nucleosides for HCV infection
|
WO2014078427A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-alanine ester of rp-nucleoside analog
|
WO2014078436A1
(en)
|
2012-11-14 |
2014-05-22 |
Idenix Pharmaceuticals, Inc. |
D-alanine ester of sp-nucleoside analog
|
RU2015123641A
(ru)
|
2012-11-19 |
2017-01-10 |
Мерк Шарп И Доум Корп. |
2-алкинилзамещенные производные нуклеозидов, предназначенные для лечения вирусных заболеваний
|
WO2014099941A1
(en)
|
2012-12-19 |
2014-06-26 |
Idenix Pharmaceuticals, Inc. |
4'-fluoro nucleosides for the treatment of hcv
|
RS61767B1
(sr)
|
2012-12-21 |
2021-05-31 |
Janssen Biopharma Inc |
4'-fluor-nukleozidi, 4'-fluor-nukleotidi i njihovi analozi za lečenje hcv
|
EP2935305A4
(en)
*
|
2012-12-21 |
2016-08-03 |
Alios Biopharma Inc |
SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGUE THEREOF
|
WO2014120981A1
(en)
|
2013-01-31 |
2014-08-07 |
Gilead Pharmasset Llc |
Combination formulation of two antiviral compounds
|
WO2014121417A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
WO2014121418A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
WO2014121416A1
(en)
|
2013-02-07 |
2014-08-14 |
Merck Sharp & Dohme Corp. |
Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
|
US9821173B2
(en)
*
|
2013-02-08 |
2017-11-21 |
Case Western Reserve University |
Anti-cancer agents and methods of use
|
TW201526899A
(zh)
|
2013-02-28 |
2015-07-16 |
Alios Biopharma Inc |
醫藥組成物
|
US9339541B2
(en)
|
2013-03-04 |
2016-05-17 |
Merck Sharp & Dohme Corp. |
Thiophosphate nucleosides for the treatment of HCV
|
US9309275B2
(en)
|
2013-03-04 |
2016-04-12 |
Idenix Pharmaceuticals Llc |
3′-deoxy nucleosides for the treatment of HCV
|
WO2014160484A1
(en)
|
2013-03-13 |
2014-10-02 |
Idenix Pharmaceuticals, Inc. |
Amino acid phosphoramidate pronucleotides of 2'-cyano, azido and amino nucleosides for the treatment of hcv
|
US9481667B2
(en)
|
2013-03-15 |
2016-11-01 |
Infinity Pharmaceuticals, Inc. |
Salts and solid forms of isoquinolinones and composition comprising and methods of using the same
|
RU2534613C2
(ru)
|
2013-03-22 |
2014-11-27 |
Александр Васильевич Иващенко |
Алкил 2-{ [(2r,3s,5r)-5-(4-амино-2-оксо-2н-пиримидин-1-ил)- -гидрокси-тетрагидро-фуран-2-илметокси]-фенокси-фосфориламино} -пропионаты, нуклеозидные ингибиторы рнк-полимеразы hcv ns5b, способы их получения и применения
|
US9187515B2
(en)
|
2013-04-01 |
2015-11-17 |
Idenix Pharmaceuticals Llc |
2′,4′-fluoro nucleosides for the treatment of HCV
|
WO2014169280A2
(en)
|
2013-04-12 |
2014-10-16 |
Achillion Pharmaceuticals, Inc. |
Deuterated nucleoside prodrugs useful for treating hcv
|
WO2014197578A1
(en)
|
2013-06-05 |
2014-12-11 |
Idenix Pharmaceuticals, Inc. |
1',4'-thio nucleosides for the treatment of hcv
|
ES2685591T3
(es)
|
2013-06-26 |
2018-10-10 |
Alios Biopharma, Inc. |
Nucleósidos, nucleótidos sustituidos y análogos de los mismos
|
CA2913206C
(en)
|
2013-06-26 |
2022-08-02 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
EP3027636B1
(en)
|
2013-08-01 |
2022-01-05 |
Idenix Pharmaceuticals LLC |
D-amino acid phosphoramidate pronucleotides of halogeno pyrimidine compounds for liver disease
|
PL3038601T3
(pl)
|
2013-08-27 |
2020-08-24 |
Gilead Pharmasset Llc |
Formulacja złożona dwóch związków przeciwwirusowych
|
EP3046924A1
(en)
|
2013-09-20 |
2016-07-27 |
IDENIX Pharmaceuticals, Inc. |
Hepatitis c virus inhibitors
|
US9943604B2
(en)
|
2013-09-20 |
2018-04-17 |
Ionis Pharmaceuticals, Inc. |
Targeted therapeutic nucleosides and their use
|
MX2021012208A
(es)
|
2013-10-04 |
2023-01-19 |
Infinity Pharmaceuticals Inc |
Compuestos heterocíclicos y usos de los mismos.
|
US9751888B2
(en)
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
WO2015054465A1
(en)
|
2013-10-11 |
2015-04-16 |
Alios Biopharma, Inc. |
Substituted nucleosides, nucleotides and analogs thereof
|
WO2015061683A1
(en)
|
2013-10-25 |
2015-04-30 |
Idenix Pharmaceuticals, Inc. |
D-amino acid phosphoramidate and d-alanine thiophosphoramidate pronucleotides of nucleoside compounds useful for the treatment of hcv
|
WO2015066370A1
(en)
|
2013-11-01 |
2015-05-07 |
Idenix Pharmaceuticals, Inc. |
D-alanine phosphoramidate pronucleotides of 2'-methyl 2'-fluoro guanosine nucleoside compounds for the treatment of hcv
|
CZ305466B6
(cs)
*
|
2013-11-04 |
2015-10-14 |
Ústav organické chemie a biochemie Akademie věd České republiky, v. v. i. |
Substituované 7-deazapurinové ribonukleosidy pro terapeutické použití
|
US20170198005A1
(en)
|
2013-11-27 |
2017-07-13 |
Idenix Pharmaceuticals Llc |
2'-dichloro and 2'-fluoro-2'-chloro nucleoside analogues for hcv infection
|
US10683321B2
(en)
|
2013-12-18 |
2020-06-16 |
Idenix Pharmaceuticals Llc |
4′-or nucleosides for the treatment of HCV
|
WO2015108048A1
(ja)
|
2014-01-15 |
2015-07-23 |
株式会社新日本科学 |
抗腫瘍作用を有するキラル核酸アジュバンド及び抗腫瘍剤
|
EP3095461A4
(en)
|
2014-01-15 |
2017-08-23 |
Shin Nippon Biomedical Laboratories, Ltd. |
Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator
|
EP3095460A4
(en)
|
2014-01-15 |
2017-08-23 |
Shin Nippon Biomedical Laboratories, Ltd. |
Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent
|
SG10201912897UA
(en)
|
2014-01-16 |
2020-02-27 |
Wave Life Sciences Ltd |
Chiral design
|
AU2015217221A1
(en)
|
2014-02-13 |
2016-08-11 |
Ligand Pharmaceuticals, Inc. |
Prodrug compounds and their uses
|
US10202386B2
(en)
|
2014-02-20 |
2019-02-12 |
Glaxosmithkline Intellectual Property (No. 2) Limited |
Pyrrolo[3,2-D]pyrimidine derivatives as inducers of human interferon
|
US20170135990A1
(en)
|
2014-03-05 |
2017-05-18 |
Idenix Pharmaceuticals Llc |
Pharmaceutical compositions comprising a 5,5-fused heteroarylene flaviviridae inhibitor and their use for treating or preventing flaviviridae infection
|
US20170066779A1
(en)
|
2014-03-05 |
2017-03-09 |
Idenix Pharmaceuticals Llc |
Solid forms of a flaviviridae virus inhibitor compound and salts thereof
|
MX2016012021A
(es)
|
2014-03-19 |
2017-04-13 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos para utilizarlos en el tratamiento de trastornos mediados por pi3k-gamma.
|
WO2015161137A1
(en)
|
2014-04-16 |
2015-10-22 |
Idenix Pharmaceuticals, Inc. |
3'-substituted methyl or alkynyl nucleosides for the treatment of hcv
|
US20150320755A1
(en)
|
2014-04-16 |
2015-11-12 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
CN106459133B
(zh)
*
|
2014-06-10 |
2019-12-06 |
安捷伦科技有限公司 |
用于“z核苷酸”的保护基团及其方法
|
CN106573011A
(zh)
|
2014-06-24 |
2017-04-19 |
艾丽奥斯生物制药有限公司 |
取代的核苷、核苷酸和其类似物
|
CA2952959C
(en)
|
2014-06-24 |
2023-03-07 |
Alios Biopharma, Inc. |
Use of nucleosides and nucleotides to treat filoviridae viral infection
|
WO2016003812A1
(en)
|
2014-07-02 |
2016-01-07 |
Ligand Pharmaceuticals, Inc. |
Prodrug compounds and uses therof
|
WO2016054491A1
(en)
|
2014-10-03 |
2016-04-07 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
TWI767201B
(zh)
|
2014-10-29 |
2022-06-11 |
美商基利科學股份有限公司 |
絲狀病毒科病毒感染之治療
|
EP3218377B1
(en)
|
2014-11-13 |
2022-04-13 |
GlaxoSmithKline Biologicals SA |
Adenine derivatives which are useful in the treatment of allergic diseases or other inflammatory conditions
|
MA41213A
(fr)
|
2014-12-19 |
2017-10-24 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
MA41441A
(fr)
|
2014-12-19 |
2017-12-12 |
Alios Biopharma Inc |
Nucléosides substitués, nucléotides et analogues de ceux-ci
|
IL302877A
(en)
|
2015-03-06 |
2023-07-01 |
Atea Pharmaceuticals Inc |
Cell-D-2'-deoxy-2'-alpha-fluoro-2'-cell-C-modified-2-different-N6-purine modified nucleotides for the treatment of hepatitis C virus
|
EP3303362B1
(en)
|
2015-06-03 |
2022-10-19 |
Teva Pharmaceuticals International GmbH |
Improved processes for the preparation of sofosbuvir and intermediates thereof
|
BR112018000054A2
(pt)
|
2015-07-02 |
2018-09-04 |
Otsuka Pharmaceutical Co., Ltd. |
composições farmacêuticas liofilizadas
|
BR112018002399A2
(pt)
|
2015-08-06 |
2018-09-25 |
Chimerix, Inc. |
nucleosídeos de pirrolopirimidina e análogos dos mesmos, úteis como agentes antivirais
|
WO2017027645A1
(en)
|
2015-08-13 |
2017-02-16 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
CN108350016B
(zh)
*
|
2015-09-02 |
2021-07-27 |
艾伯维公司 |
抗病毒四氢呋喃衍生物
|
EP3350183A1
(en)
|
2015-09-14 |
2018-07-25 |
Infinity Pharmaceuticals, Inc. |
Solid forms of isoquinolinone derivatives, process of making, compositions comprising, and methods of using the same
|
MA42819A
(fr)
|
2015-09-16 |
2018-07-25 |
Gilead Sciences Inc |
Procédés pour le traitement d'infections virales à arenaviridae et coronaviridae
|
MX2018003212A
(es)
*
|
2015-09-23 |
2018-07-06 |
Merck Sharp & Dohme |
Inhibidores de transcriptasa inversa de nucleosido 4'-substituido y preparaciones de los mismos.
|
MX363780B
(es)
|
2015-12-03 |
2019-04-03 |
Glaxosmithkline Ip Dev Ltd |
Dinucleótidos de purina cíclica como moduladores del estimulador de los genes de interferón.
|
WO2017156262A1
(en)
|
2016-03-09 |
2017-09-14 |
Alios Biopharma, Inc. |
Acyclic antivirals
|
WO2017161116A1
(en)
|
2016-03-17 |
2017-09-21 |
Infinity Pharmaceuticals, Inc. |
Isotopologues of isoquinolinone and quinazolinone compounds and uses thereof as pi3k kinase inhibitors
|
ES2962269T3
(es)
|
2016-03-24 |
2024-03-18 |
Novartis Ag |
Análogos de nucleósidos alquinil como inhibidores del rinovirus humano
|
CN109563081A
(zh)
|
2016-04-07 |
2019-04-02 |
葛兰素史克知识产权开发有限公司 |
可用作蛋白调节剂的杂环酰胺类
|
HRP20220936T1
(hr)
|
2016-04-07 |
2022-10-28 |
Glaxosmithkline Intellectual Property Development Limited |
Heterociklički amidi korisni kao modulatori proteina
|
JP7129703B2
(ja)
|
2016-04-28 |
2022-09-02 |
エモリー ユニバーシティー |
アルキン含有ヌクレオチド及びヌクレオシド治療組成物並びにそれらに関連した使用
|
WO2017214269A1
(en)
|
2016-06-08 |
2017-12-14 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
AU2017281797A1
(en)
|
2016-06-24 |
2019-01-24 |
Infinity Pharmaceuticals, Inc. |
Combination therapies
|
US10202412B2
(en)
|
2016-07-08 |
2019-02-12 |
Atea Pharmaceuticals, Inc. |
β-D-2′-deoxy-2′-substituted-4′-substituted-2-substituted-N6-substituted-6-aminopurinenucleotides for the treatment of paramyxovirus and orthomyxovirus infections
|
WO2018013937A1
(en)
|
2016-07-14 |
2018-01-18 |
Atea Pharmaceuticals, Inc. |
Beta-d-2'-deoxy-2'-alpha-fluoro-2'-beta-c-substituted-4'-fluoro-n6-substituted-6-amino-2-substituted purine nucleotides for the treatment of hepatitis c virus infection
|
CN109890831A
(zh)
*
|
2016-08-12 |
2019-06-14 |
詹森生物制药有限公司 |
被取代的核苷、核苷酸以及它们的类似物
|
KR20220146668A
(ko)
|
2016-09-07 |
2022-11-01 |
아테아 파마슈티컬즈, 인크. |
Rna 바이러스 치료를 위한 2'-치환된-n6-치환된 퓨린 뉴클레오티드
|
WO2018089306A1
(en)
*
|
2016-11-10 |
2018-05-17 |
Oyagen, Inc. |
Methods of treating and inhibiting ebola virus infection
|
CN110177544A
(zh)
|
2016-11-29 |
2019-08-27 |
普尔泰克健康有限公司 |
用于递送治疗剂的外泌体
|
WO2018110643A1
(ja)
*
|
2016-12-14 |
2018-06-21 |
ヤマサ醤油株式会社 |
抗ウイルス活性を示すヌクレオシド誘導体
|
GEP20237457B
(en)
|
2017-02-01 |
2023-01-10 |
Atea Pharmaceuticals Inc |
Nucleotide hemi-sulfate salt for treatment of hepatitis c virus
|
TW201836615A
(zh)
|
2017-03-14 |
2018-10-16 |
美商基利科學股份有限公司 |
治療貓冠狀病毒感染之方法
|
AU2018262501B2
(en)
|
2017-05-01 |
2020-12-10 |
Gilead Sciences, Inc. |
Crystalline forms of (S) 2 ethylbutyl 2 (((S) (((2R,3S,4R,5R) 5 (4 aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy) phosphoryl)amino)propanoate
|
US10675296B2
(en)
|
2017-07-11 |
2020-06-09 |
Gilead Sciences, Inc. |
Compositions comprising an RNA polymerase inhibitor and cyclodextrin for treating viral infections
|
ES2969496T3
(es)
|
2017-08-01 |
2024-05-20 |
Gilead Sciences Inc |
Formas cristalinas de ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-il)-4-fluoro-2,5-dihidrofuran-2- il)oxi)metil)(fenoxi)fosforil)-L-alaninato de etilo para tratar infecciones virales
|
KR20200035438A
(ko)
|
2017-08-03 |
2020-04-03 |
오쓰까 세이야꾸 가부시키가이샤 |
약물 화합물 및 이의 정제 방법
|
KR20200098483A
(ko)
|
2017-09-18 |
2020-08-20 |
얀센 바이오파마, 인크. |
치환된 뉴클레오시드, 뉴클레오티드 및 이들의 유사체
|
WO2019060692A1
(en)
|
2017-09-21 |
2019-03-28 |
Chimerix, Inc. |
MORPHIC FORMS OF 4-AMINO-7- (3,4-DIHYDROXY-5- (HYDROXYMETHYL) -ETRAHYDROFURAN-2-YL) -2-METHYL-7H-PYRROLO [2,3-D] PYRIMIDINE-5-CARBOXAMIDE AND THEIR USES
|
US20210238172A1
(en)
|
2017-10-05 |
2021-08-05 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides useful as protein modulators and methods of using the same
|
EP3692034A1
(en)
|
2017-10-05 |
2020-08-12 |
GlaxoSmithKline Intellectual Property Development Limited |
Modulators of stimulator of interferon genes (sting)
|
JP2021509907A
(ja)
|
2018-01-09 |
2021-04-08 |
リガンド・ファーマシューティカルズ・インコーポレイテッド |
アセタール化合物およびその治療的使用
|
CN112105625A
(zh)
|
2018-03-07 |
2020-12-18 |
赛诺菲 |
核苷酸前体、核苷酸类似物以及含其的寡聚化合物
|
EP3773753A4
(en)
|
2018-04-10 |
2021-12-22 |
ATEA Pharmaceuticals, Inc. |
TREATMENT OF PATIENTS INFECTED WITH THE HEPATITIS C VIRUS WITH CIRRHOSIS
|
BR112020020804A2
(pt)
|
2018-04-12 |
2021-01-12 |
Modis Therapeutics Inc. |
Pró-fármacos de desoxinucleosídeos para tratamento de doenças causadas por agrupamentos de nucleotídeos não balanceados
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
BR112021010351A2
(pt)
|
2018-12-12 |
2021-08-31 |
Janssen Biopharma, Inc. |
Análogos de ciclopentil nucleosídeos como antivirais
|
KR20210102360A
(ko)
|
2018-12-12 |
2021-08-19 |
얀센 바이오파마, 인코퍼레이트. |
항바이러스제로서의 사이클로부틸 뉴클레오시드 유사체
|
EP3969452A1
(en)
|
2019-05-16 |
2022-03-23 |
Stingthera, Inc. |
Benzo[b][1,8]naphthyridine acetic acid derivatives and methods of use
|
JP2022533390A
(ja)
|
2019-05-16 |
2022-07-22 |
スティングセラ インコーポレイテッド |
オキソアクリジニル酢酸誘導体および使用方法
|
GB201910305D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
GB201910304D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
CN114728999A
(zh)
|
2019-09-05 |
2022-07-08 |
赛诺菲 |
含有核苷酸类似物的寡核苷酸
|
TWI789695B
(zh)
|
2020-01-27 |
2023-01-11 |
美商基利科學股份有限公司 |
治療sars cov-2感染之方法
|
WO2021158248A1
(en)
|
2020-02-04 |
2021-08-12 |
Oyagen, Inc. |
Method for treating coronavirus infections
|
US10874687B1
(en)
|
2020-02-27 |
2020-12-29 |
Atea Pharmaceuticals, Inc. |
Highly active compounds against COVID-19
|
TWI785528B
(zh)
|
2020-03-12 |
2022-12-01 |
美商基利科學股份有限公司 |
1’-氰基核苷之製備方法
|
EP4132651A1
(en)
|
2020-04-06 |
2023-02-15 |
Gilead Sciences, Inc. |
Inhalation formulations of 1'-cyano substituted carbanucleoside analogs
|
EP4157272A1
(en)
|
2020-05-29 |
2023-04-05 |
Gilead Sciences, Inc. |
Remdesivir treatment methods
|
BR112022026321A2
(pt)
|
2020-06-24 |
2023-01-17 |
Gilead Sciences Inc |
Análogos de 1'-ciano nucleosídeo e usos dos mesmos
|
US11926645B2
(en)
|
2020-08-27 |
2024-03-12 |
Gilead Sciences, Inc. |
Compounds and methods for treatment of viral infections
|
EP4232455A2
(en)
|
2020-10-20 |
2023-08-30 |
Sanofi |
Novel ligands for asialoglycoprotein receptor
|
CN112979735B
(zh)
*
|
2021-04-25 |
2021-09-17 |
南京颐媛生物医学研究院有限公司 |
抗肝炎病毒的化合物及其制备方法和应用
|
CN113278041B
(zh)
*
|
2021-07-16 |
2021-10-19 |
南京颐媛生物医学研究院有限公司 |
一种核苷磷酸酯及其合成方法与抗肝炎病毒的制药应用
|
TW202400185A
(zh)
|
2022-03-02 |
2024-01-01 |
美商基利科學股份有限公司 |
用於治療病毒感染的化合物及方法
|
CN115651047B
(zh)
*
|
2022-11-14 |
2023-03-17 |
天津奥瑞芙生物医药有限公司 |
2’-o-甲基核苷的制备方法
|
CN117362369B
(zh)
*
|
2023-10-09 |
2024-04-19 |
长沙晨辰医药科技有限公司 |
一锅法合成核苷二磷酸
|