DZ3042A1 - Dérivés d'isothiazole nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant. - Google Patents
Dérivés d'isothiazole nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant.Info
- Publication number
- DZ3042A1 DZ3042A1 DZ000085A DZ000085A DZ3042A1 DZ 3042 A1 DZ3042 A1 DZ 3042A1 DZ 000085 A DZ000085 A DZ 000085A DZ 000085 A DZ000085 A DZ 000085A DZ 3042 A1 DZ3042 A1 DZ 3042A1
- Authority
- DZ
- Algeria
- Prior art keywords
- preparation
- pharmaceutical compositions
- compositions containing
- isothiazole derivatives
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/02—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
- C07D275/03—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/44—Oxygen and nitrogen or sulfur and nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13493399P | 1999-05-19 | 1999-05-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
DZ3042A1 true DZ3042A1 (fr) | 2004-03-27 |
Family
ID=22465672
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DZ000085A DZ3042A1 (fr) | 1999-05-19 | 2000-05-17 | Dérivés d'isothiazole nouveaux, procédé pour leur préparation et compositions pharmaceutiques les contenant. |
Country Status (21)
Country | Link |
---|---|
US (1) | US6380214B1 (fr) |
EP (1) | EP1187826B1 (fr) |
JP (2) | JP3692041B2 (fr) |
AR (1) | AR029634A1 (fr) |
AT (1) | ATE349440T1 (fr) |
AU (1) | AU4137400A (fr) |
BR (1) | BR0010746A (fr) |
CA (1) | CA2374247C (fr) |
CO (1) | CO5170417A1 (fr) |
DE (1) | DE60032601T2 (fr) |
DZ (1) | DZ3042A1 (fr) |
ES (1) | ES2276681T3 (fr) |
GT (1) | GT200000069A (fr) |
HN (1) | HN2000000051A (fr) |
MA (1) | MA26733A1 (fr) |
MX (1) | MXPA01011920A (fr) |
PA (1) | PA8494101A1 (fr) |
PE (1) | PE20010152A1 (fr) |
TN (1) | TNSN00104A1 (fr) |
UY (1) | UY26143A1 (fr) |
WO (1) | WO2000071532A1 (fr) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1158985B1 (fr) | 1999-01-13 | 2011-12-28 | Bayer HealthCare LLC | DIPHENYLE UREES A SUBSTITUTION OMEGA-CARBOXY ARYLE EN TANT QU'INHIBITEURS DE LA KINASE p38 |
US8124630B2 (en) | 1999-01-13 | 2012-02-28 | Bayer Healthcare Llc | ω-carboxyaryl substituted diphenyl ureas as raf kinase inhibitors |
ATE279410T1 (de) | 2000-02-07 | 2004-10-15 | Bristol Myers Squibb Co | 3-aminopyrazole als inhibitoren von cyclinabhängigen kinasen |
GB0003154D0 (en) | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
US7105682B2 (en) | 2001-01-12 | 2006-09-12 | Amgen Inc. | Substituted amine derivatives and methods of use |
US7102009B2 (en) | 2001-01-12 | 2006-09-05 | Amgen Inc. | Substituted amine derivatives and methods of use |
US8329924B2 (en) * | 2001-06-11 | 2012-12-11 | Vertex Pharmaceuticals (Canada) Incorporated | Compounds and methods for the treatment or prevention of Flavivirus infections |
AP1753A (en) * | 2001-06-11 | 2007-07-18 | Shire Biochem Inc | Thiophene derivatives as antiviral agents for flavvivirus infection |
SE0102616D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
SE0102617D0 (sv) * | 2001-07-25 | 2001-07-25 | Astrazeneca Ab | Novel compounds |
US6924276B2 (en) | 2001-09-10 | 2005-08-02 | Warner-Lambert Company | Diacid-substituted heteroaryl derivatives as matrix metalloproteinase inhibitors |
WO2003068229A1 (fr) | 2002-02-11 | 2003-08-21 | Bayer Pharmaceuticals Corporation | N-oxydes de pyridine, de quinoline, et d'isoquinoline en tant qu'inhibiteurs de kinase |
PT1478358E (pt) | 2002-02-11 | 2013-09-11 | Bayer Healthcare Llc | Tosilato de sorafenib para o tratamento de doenças caracterizadas por angiogénese anormal |
US6989451B2 (en) * | 2002-06-04 | 2006-01-24 | Valeant Research & Development | Heterocyclic compounds and uses thereof |
WO2003105843A1 (fr) * | 2002-06-13 | 2003-12-24 | Kinetek Pharmaceuticals, Inc. | Procedes d'utilisation de derives d'izothiazole pour traiter un cancer ou une inflammation |
WO2004004712A1 (fr) * | 2002-07-09 | 2004-01-15 | Fasgen, Llc | Methodes de traitement d'infections microbiennes chez les humains et les animaux |
WO2004005277A1 (fr) * | 2002-07-09 | 2004-01-15 | Fasgen, Inc. | Nouveaux composés, compositions pharmaceutiques les contenant et méthodes d'utilisation desdits composés |
AU2003281664A1 (en) * | 2002-07-25 | 2004-02-16 | Pfizer Products Inc. | Isothiazole derivatives useful as anticancer agents |
AU2003302665B2 (en) * | 2002-11-15 | 2009-12-24 | Symphony Evolution, Inc. | Kinase modulators |
KR101058696B1 (ko) * | 2002-12-10 | 2011-08-22 | 바이로켐 파마 인코포레이티드 | 후라비바이러스 감염의 치료 또는 예방을 위한 화합물과방법 |
SE0300092D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
SE0300091D0 (sv) * | 2003-01-15 | 2003-01-15 | Astrazeneca Ab | Novel compounds |
US7534802B2 (en) * | 2003-03-07 | 2009-05-19 | Santen Pharmaceutical Co., Ltd. | Compounds having 4-pyridylalkylthio group as substituent |
DE602004011340T2 (de) | 2003-05-20 | 2008-11-06 | Bayer Healthcare Llc | Diaryl-harnstoffe mit kinasehemmender wirkung |
UA84156C2 (ru) | 2003-07-23 | 2008-09-25 | Байер Фармасьютикалс Корпорейшн | Фторозамещённая омега-карбоксиарилдифенилмочевина для лечения и профилактики болезней и состояний |
JP4626353B2 (ja) * | 2004-02-17 | 2011-02-09 | 参天製薬株式会社 | 置換又は無置換アミノ基を導入した4−ピリジルアルキルチオ基を有する新規環式化合物 |
CN1918127B (zh) * | 2004-02-17 | 2012-02-15 | 参天制药株式会社 | 具有引入了取代或无取代氨基的4-吡啶基烷硫基的环状化合物 |
KR101179840B1 (ko) | 2004-02-17 | 2012-09-04 | 산텐 세이야꾸 가부시키가이샤 | 치환 또는 무치환 아미노기를 도입한 4-피리딜알킬티오기를갖는 신규 고리형 화합물 |
WO2005090313A1 (fr) | 2004-03-18 | 2005-09-29 | Pfizer Limited | Sulfamides n-(1-arylpyrazol-4l) et leur utilisation en tant qu'anti-parasitaires |
WO2005110994A2 (fr) | 2004-04-30 | 2005-11-24 | Bayer Pharmaceuticals Corporation | Derives de pyrazolyl uree substitues utiles dans le traitement du cancer |
BRPI0514667A (pt) * | 2004-08-26 | 2008-06-17 | Pfizer Prod Inc | processos para a preparação de derivados de isotiazol |
JP4585978B2 (ja) * | 2005-03-03 | 2010-11-24 | 参天製薬株式会社 | キノリルアルキルチオ基を有する新規環式化合物 |
KR20080016597A (ko) * | 2005-05-13 | 2008-02-21 | 바이로켐 파마 인코포레이티드 | 플라비바이러스 감염의 예방 또는 치료용 화합물 및 그의예방 또는 치료 방법 |
US7932390B2 (en) | 2006-06-29 | 2011-04-26 | Hoffman-La Roche Inc. | Substituted thieno[3,2-C]pyridine carboxylic acid derivatives |
PL2104674T3 (pl) | 2006-11-15 | 2013-12-31 | Vertex Pharmaceuticals Canada Incorporated | Analogi tiofenu do leczenia lub zapobiegania zakażeniom flawiwirusowym |
CA2678735A1 (fr) * | 2007-02-26 | 2008-09-04 | Santen Pharmaceutical Co., Ltd. | Nouveau derive de pyrrole ayant un groupe ureide et un groupe aminocarbonyle comme substituants |
WO2008153042A1 (fr) * | 2007-06-11 | 2008-12-18 | Kyowa Hakko Kirin Co., Ltd. | Agent antitumoral |
MX2010001636A (es) | 2007-08-14 | 2010-03-15 | Hoffmann La Roche | Derivados de pirazolo[3,4-d]-pirimidina como agentes antiproliferativos. |
WO2010151710A2 (fr) * | 2009-06-25 | 2010-12-29 | Medolution Limited | Composés hétérocycliques substitués utilisés en tant qu'inhibiteurs de la kinase et leur procédé d'utilisation |
AR092809A1 (es) | 2012-03-16 | 2015-05-06 | Axikin Pharmaceuticals Inc | 3,5-diaminopirazol como inhibidor de quinasa |
NZ631142A (en) | 2013-09-18 | 2016-03-31 | Axikin Pharmaceuticals Inc | Pharmaceutically acceptable salts of 3,5-diaminopyrazole kinase inhibitors |
TWI703133B (zh) | 2014-12-23 | 2020-09-01 | 美商艾克斯基製藥公司 | 3,5-二胺基吡唑激酶抑制劑 |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1950990A1 (de) * | 1968-10-17 | 1970-05-14 | Ciba Geigy | Verfahren zur Herstellung von neuen triazacyclischen Verbindungen |
GB1355513A (en) * | 1971-04-07 | 1974-06-05 | May & Baker Ltd | Isothiazole derivatives |
DE2408234A1 (de) * | 1974-02-21 | 1975-09-04 | Celamerck Gmbh & Co Kg | Isothiazolylharnstoffe |
US4075001A (en) * | 1976-06-18 | 1978-02-21 | Fmc Corporation | 3-Aminoisothiazole derivatives as herbicides |
US4057416A (en) * | 1976-06-18 | 1977-11-08 | Fmc Corporation | 3-Alkylthio-, 3-alkylsulfinyl-, and 3-alkylsulfonylisothiazole derivatives as herbicides |
US4059433A (en) * | 1976-06-18 | 1977-11-22 | Fmc Corporation | 3-Alkoxyisothiazole derivatives as herbicides |
DE3529247A1 (de) * | 1985-05-17 | 1986-11-20 | Bayer Ag, 5090 Leverkusen | Verwendung von thienylharnstoffen und -isoharnstoffen als leistungsfoerdernde mittel bei tieren, neue thienylharnstoffe und -isoharnstoffe und ihre herstellung |
DE3540377A1 (de) * | 1985-11-14 | 1987-05-21 | Bayer Ag | Thienooxazinone, verfahren zu ihrer herstellung und ihre verwendung als leistungsfoerderer |
DE3541631A1 (de) * | 1985-11-26 | 1987-05-27 | Bayer Ag | Selektiv-fungizide verwendung von thienylharnstoff-derivaten |
US4859699A (en) * | 1987-07-20 | 1989-08-22 | Sandoz Ltd. | Substituted N-benzoyl-N'-thienylureas |
US6177401B1 (en) | 1992-11-13 | 2001-01-23 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften | Use of organic compounds for the inhibition of Flk-1 mediated vasculogenesis and angiogenesis |
DE4328425A1 (de) * | 1993-08-24 | 1995-03-02 | Basf Ag | Acylamino-substituierte Isoxazol- bzw. Isothiazolderivate, Verfahren zu deren Herstellung und ihre Verwendung |
TW276256B (fr) * | 1993-08-26 | 1996-05-21 | Takeda Pharm Industry Co Ltd | |
AU700964B2 (en) * | 1994-11-10 | 1999-01-14 | Cor Therapeutics, Inc. | Pharmaceutical pyrazole compositions useful as inhibitors of protein kinases |
US5792767A (en) * | 1995-01-27 | 1998-08-11 | Abbott Laboratories | Bicyclic substituted hexahydrobenz e! isoindole alpha-1 adrenergic antagonists |
US5773459A (en) * | 1995-06-07 | 1998-06-30 | Sugen, Inc. | Urea- and thiourea-type compounds |
WO1998052559A1 (fr) * | 1997-05-23 | 1998-11-26 | Bayer Corporation | Inhibiteurs de raf kinase |
US6037340A (en) * | 1997-05-28 | 2000-03-14 | Cadus Pharmaceutical Corporation | Synthesis and use of thiophene- and pyrrole-based heteroaromatic compounds |
UA60365C2 (uk) * | 1998-06-04 | 2003-10-15 | Пфайзер Продактс Інк. | Похідні ізотіазолу, спосіб їх одержання, фармацевтична композиція та спосіб лікування гіперпроліферативного захворювання у ссавця |
-
2000
- 2000-04-12 HN HN2000000051A patent/HN2000000051A/es unknown
- 2000-04-17 US US09/549,893 patent/US6380214B1/en not_active Expired - Fee Related
- 2000-04-17 CO CO00028307A patent/CO5170417A1/es not_active Application Discontinuation
- 2000-04-18 PA PA20008494101A patent/PA8494101A1/es unknown
- 2000-05-03 ES ES00920969T patent/ES2276681T3/es not_active Expired - Lifetime
- 2000-05-03 MX MXPA01011920A patent/MXPA01011920A/es active IP Right Grant
- 2000-05-03 BR BR0010746-8A patent/BR0010746A/pt not_active Application Discontinuation
- 2000-05-03 CA CA002374247A patent/CA2374247C/fr not_active Expired - Fee Related
- 2000-05-03 EP EP00920969A patent/EP1187826B1/fr not_active Expired - Lifetime
- 2000-05-03 JP JP2000619789A patent/JP3692041B2/ja not_active Expired - Lifetime
- 2000-05-03 DE DE60032601T patent/DE60032601T2/de not_active Expired - Fee Related
- 2000-05-03 AT AT00920969T patent/ATE349440T1/de not_active IP Right Cessation
- 2000-05-03 AU AU41374/00A patent/AU4137400A/en not_active Abandoned
- 2000-05-03 WO PCT/IB2000/000570 patent/WO2000071532A1/fr active IP Right Grant
- 2000-05-15 UY UY26143A patent/UY26143A1/es not_active Application Discontinuation
- 2000-05-16 PE PE2000000458A patent/PE20010152A1/es not_active Application Discontinuation
- 2000-05-17 AR ARP000102369A patent/AR029634A1/es not_active Application Discontinuation
- 2000-05-17 GT GT200000069A patent/GT200000069A/es unknown
- 2000-05-17 TN TNTNSN00104A patent/TNSN00104A1/fr unknown
- 2000-05-17 MA MA25977A patent/MA26733A1/fr unknown
- 2000-05-17 DZ DZ000085A patent/DZ3042A1/fr active
-
2004
- 2004-07-20 JP JP2004211640A patent/JP2005008641A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
TNSN00104A1 (fr) | 2005-11-10 |
DE60032601D1 (de) | 2007-02-08 |
AR029634A1 (es) | 2003-07-10 |
DE60032601T2 (de) | 2007-11-15 |
ATE349440T1 (de) | 2007-01-15 |
GT200000069A (es) | 2001-11-08 |
CO5170417A1 (es) | 2002-06-27 |
CA2374247A1 (fr) | 2000-11-30 |
MXPA01011920A (es) | 2002-05-06 |
CA2374247C (fr) | 2008-01-22 |
JP3692041B2 (ja) | 2005-09-07 |
UY26143A1 (es) | 2000-12-29 |
HN2000000051A (es) | 2001-02-02 |
EP1187826B1 (fr) | 2006-12-27 |
EP1187826A1 (fr) | 2002-03-20 |
AU4137400A (en) | 2000-12-12 |
JP2003500401A (ja) | 2003-01-07 |
ES2276681T3 (es) | 2007-07-01 |
US6380214B1 (en) | 2002-04-30 |
WO2000071532A1 (fr) | 2000-11-30 |
MA26733A1 (fr) | 2004-12-20 |
PE20010152A1 (es) | 2001-02-08 |
PA8494101A1 (es) | 2003-09-05 |
JP2005008641A (ja) | 2005-01-13 |
BR0010746A (pt) | 2002-02-13 |
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