DK145289D0 - Aristeromycin/adenosinderivater samt anvendelsen heraf - Google Patents

Aristeromycin/adenosinderivater samt anvendelsen heraf

Info

Publication number
DK145289D0
DK145289D0 DK145289A DK145289A DK145289D0 DK 145289 D0 DK145289 D0 DK 145289D0 DK 145289 A DK145289 A DK 145289A DK 145289 A DK145289 A DK 145289A DK 145289 D0 DK145289 D0 DK 145289D0
Authority
DK
Denmark
Prior art keywords
aristeromycine
adenosin
derivatives
adenosin derivatives
Prior art date
Application number
DK145289A
Other languages
English (en)
Other versions
DK171645B1 (da
DK145289A (da
Inventor
Michael L Edwards
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK145289D0 publication Critical patent/DK145289D0/da
Publication of DK145289A publication Critical patent/DK145289A/da
Application granted granted Critical
Publication of DK171645B1 publication Critical patent/DK171645B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052—Imidazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056—Triazole or tetrazole radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/167—Purine radicals with ribosyl as the saccharide radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK145289A 1988-03-25 1989-03-22 Adenosinderivater samt farmaceutisk præparat DK171645B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/173,782 US4996308A (en) 1988-03-25 1988-03-25 Derivatives with unsaturated substitutions for the 5'-hydroxymethyl group
US17378288 1988-03-25

Publications (3)

Publication Number Publication Date
DK145289D0 true DK145289D0 (da) 1989-03-22
DK145289A DK145289A (da) 1989-09-26
DK171645B1 DK171645B1 (da) 1997-03-03

Family

ID=22633462

Family Applications (1)

Application Number Title Priority Date Filing Date
DK145289A DK171645B1 (da) 1988-03-25 1989-03-22 Adenosinderivater samt farmaceutisk præparat

Country Status (21)

Country Link
US (1) US4996308A (da)
EP (1) EP0334361B1 (da)
JP (1) JP2829737B2 (da)
KR (1) KR0135529B1 (da)
CN (1) CN1023804C (da)
AR (1) AR247403A1 (da)
AT (1) ATE121415T1 (da)
AU (1) AU606792B2 (da)
CA (1) CA1322195C (da)
DE (1) DE68922235T2 (da)
DK (1) DK171645B1 (da)
ES (1) ES2074060T3 (da)
FI (1) FI90877C (da)
HU (1) HU203561B (da)
IE (1) IE67543B1 (da)
IL (1) IL89689A0 (da)
NO (1) NO171856C (da)
NZ (1) NZ228422A (da)
PH (1) PH26776A (da)
PT (1) PT90080B (da)
ZA (1) ZA892105B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3924424A1 (de) * 1989-07-24 1991-01-31 Boehringer Mannheim Gmbh Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung
CA2027023C (en) * 1989-10-11 2001-12-25 Esa T. Jarvi Inosine/guanosine derivatives
AU629988B2 (en) * 1989-10-11 1992-10-15 Merrell Dow Pharmaceuticals Inc. Inosine/guanosine derivatives as antineoplastic agents
GB8926417D0 (en) * 1989-11-22 1990-01-10 Wellcome Found Heterocyclic compounds
JPH0421682A (ja) * 1990-05-11 1992-01-24 Asahi Chem Ind Co Ltd ２―フルオロネプラノシンａおよびその製造法
GB9205071D0 (en) * 1992-03-09 1992-04-22 Wellcome Found Therapeutic nucleosides
US5399580A (en) * 1993-03-08 1995-03-21 Burroughs Wellcome Co. Therapeutic nucleosides-uses
EP0690068A4 (en) * 1993-03-18 1996-07-31 Akira Matsuda NOVEL 2'-METHYLIDENENUCLEOTIDE COMPOUND, PROCESS FOR OBTAINING THIS COMPOUND AND ITS PHARMACEUTICAL USE
US5736549A (en) * 1994-10-05 1998-04-07 Chiroscience Limited Hypoxanthine and guanine compounds
GB9600142D0 (en) * 1996-01-05 1996-03-06 Wellcome Found Chemical compounds
CZ9901996A3 (cs) * 1999-06-04 2001-01-17 Ústav organické chemie a biochemie AV ČR Nové 6-fenylpurinové 9-ß-D-ribonukleosidy s antineoplastickým účinkem, jejich použití k přípravě farmaceutických preparátů a farmaceutické přípravky, které je obsahují
EP1183034B1 (en) 1999-06-09 2005-11-23 Anticancer, Inc. Modulators of methylation for control of bacterial virulence
US6579857B1 (en) * 1999-06-11 2003-06-17 Evanston Northwestern Healthcare Research Institute Combination cancer therapy comprising adenosine and deaminase enzyme inhibitors
JP5230052B2 (ja) * 2000-05-26 2013-07-10 イデニクス（ケイマン）リミテツド フラビウイルスおよびペスチウイルス治療のための方法および組成物
US20040162422A1 (en) * 2001-03-20 2004-08-19 Adrian Hall Chemical compounds
KR20040036417A (ko) * 2002-10-25 2004-04-30 정낙신 항암 활성을 갖는 티오뉴클레오시드 유도체 및 이를함유하는 약학적 조성물
JP5002851B2 (ja) * 2005-01-20 2012-08-15 独立行政法人理化学研究所 イミダゾピリジン誘導体
CN102746304B (zh) * 2012-06-21 2014-03-19 成都苑东药业有限公司 一种嘌呤胺类化合物及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1113851A (en) * 1965-05-29 1968-05-15 Upjohn Co Decoyinine derivatives
US3472837A (en) * 1966-10-10 1969-10-14 Syntex Corp Unsaturated nucleosides and process for their preparation
US3575959A (en) * 1969-05-13 1971-04-20 Merck & Co Inc 5'-substituted ribofuranosyl nucleosides
US3585189A (en) * 1969-06-27 1971-06-15 Syntex Corp Unsaturated nucleosides and processes for their preparation
US3910885A (en) * 1974-03-12 1975-10-07 Syntex Inc 4-Alkoxy nucleosides and intermediates therefore
DE3587500T2 (de) * 1984-12-04 1993-12-16 Lilly Co Eli Tumorbehandlung bei Säugetieren.
GB8708050D0 (en) * 1987-04-03 1987-05-07 Wellcome Found Therapeutic nucleosides
NZ225906A (en) * 1987-08-26 1990-10-26 Merrell Dow Pharma Aristeromycin/adenosine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ATE121415T1 (de) 1995-05-15
NZ228422A (en) 1991-04-26
DK171645B1 (da) 1997-03-03
FI891339A (fi) 1989-09-26
DE68922235T2 (de) 1995-08-31
NO891248L (no) 1989-09-26
EP0334361A3 (en) 1991-04-03
NO891248D0 (no) 1989-03-21
JP2829737B2 (ja) 1998-12-02
IE67543B1 (en) 1996-04-17
AR247403A1 (es) 1994-12-29
JPH01283285A (ja) 1989-11-14
NO171856B (no) 1993-02-01
AU606792B2 (en) 1991-02-14
AU3173789A (en) 1989-09-28
DK145289A (da) 1989-09-26
HUT49367A (en) 1989-09-28
DE68922235D1 (de) 1995-05-24
EP0334361A2 (en) 1989-09-27
FI90877B (fi) 1993-12-31
CN1023804C (zh) 1994-02-16
CA1322195C (en) 1993-09-14
PT90080B (pt) 1994-06-30
IE890953L (en) 1989-09-25
KR890014573A (ko) 1989-10-24
HU203561B (en) 1991-08-28
CN1036579A (zh) 1989-10-25
IL89689A0 (en) 1989-09-28
PT90080A (pt) 1989-11-10
FI90877C (fi) 1994-04-11
KR0135529B1 (ko) 1998-04-23
ES2074060T3 (es) 1995-09-01
FI891339A0 (fi) 1989-03-21
PH26776A (en) 1992-10-13
ZA892105B (en) 1989-11-29
US4996308A (en) 1991-02-26
EP0334361B1 (en) 1995-04-19
NO171856C (no) 1993-05-12

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Legal Events

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B1 Patent granted (law 1993)
PBP Patent lapsed

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