DK0831098T3 - Mellemprodukter og fremgangsmåde til fremstilling af olanzapin - Google Patents

Mellemprodukter og fremgangsmåde til fremstilling af olanzapin

Info

Publication number: DK0831098T3
Authority: DK; Denmark
Prior art keywords: olanzapine; intermediates; preparation
Prior art date: 1996-09-23

Application number

DK97307383T

Other languages

Danish (da)

English (en)

Inventor

Charles Arthur Bunnell

Samuel Dean Larsen

Susan Marie Reutzel

Gregory Alan Stephenson

John Richard Nichols

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-23

Filing date

1997-09-22

Publication date

2002-05-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0831098(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-09-22 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2002-05-21 Application granted granted Critical

2002-05-21 Publication of DK0831098T3 publication Critical patent/DK0831098T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Medicinal Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biomedical Technology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Psychiatry (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

DK97307383T 1996-09-23 1997-09-22 Mellemprodukter og fremgangsmåde til fremstilling af olanzapin DK0831098T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2648796P	1996-09-23	1996-09-23

Publications (1)

Publication Number	Publication Date
DK0831098T3 true DK0831098T3 (da)	2002-05-21

Family

ID=21832120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK97307383T DK0831098T3 (da)	1996-09-23	1997-09-22	Mellemprodukter og fremgangsmåde til fremstilling af olanzapin

Country Status (36)

Country	Link
US (1)	US6020487A (uk)
EP (1)	EP0831098B1 (uk)
JP (2)	JP2001500877A (uk)
KR (1)	KR100560015B1 (uk)
CN (1)	CN1122036C (uk)
AR (1)	AR013838A1 (uk)
AT (1)	ATE209208T1 (uk)
AU (1)	AU719441B2 (uk)
BR (1)	BR9712100A (uk)
CA (1)	CA2265712C (uk)
CO (1)	CO4910140A1 (uk)
CZ (1)	CZ299248B6 (uk)
DE (1)	DE69708428T2 (uk)
DK (1)	DK0831098T3 (uk)
EA (1)	EA001642B1 (uk)
EG (1)	EG23861A (uk)
ES (1)	ES2166051T3 (uk)
HK (1)	HK1009807A1 (uk)
HU (1)	HU226484B1 (uk)
ID (1)	ID27275A (uk)
IL (1)	IL128962A (uk)
IN (1)	IN187156B (uk)
MY (1)	MY125565A (uk)
NO (1)	NO323980B1 (uk)
NZ (1)	NZ334448A (uk)
PE (1)	PE110398A1 (uk)
PL (3)	PL196068B1 (uk)
PT (1)	PT831098E (uk)
RS (1)	RS49598B (uk)
SI (1)	SI0831098T1 (uk)
SV (1)	SV1997000081A (uk)
TR (1)	TR199900640T2 (uk)
TW (1)	TW470746B (uk)
UA (1)	UA59371C2 (uk)
WO (1)	WO1998012199A1 (uk)
ZA (1)	ZA978515B (uk)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL154688A0 (en) *	2000-08-31	2003-09-17	Reddys Lab Ltd Dr	Hydrates of olanzapine and processes for the preparation thereof
US6740753B2 (en) *	2001-01-04	2004-05-25	Geneva Pharmaceuticals, Inc.	Olanzapine crystal modification
WO2003037903A1 (en) *	2001-10-29	2003-05-08	Dr. Reddy's Laboratories Ltd.	Olanzapine dihydrate-ii a process for its preparation and use thereof
WO2003055438A2 (en)	2001-12-24	2003-07-10	Sun Pharmaceutical Industries Limited	Crystalline form i of 2-methyl-4-(4-methyl-1-piperazinyl) 10h thieno [2,3-b][1,5]benzodiazepine
AU2003243153A1 (en) *	2002-04-23	2003-11-10	Dr. Reddy's Laboratories Limited	Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
EP1513846B1 (en)	2002-05-31	2011-03-02	Sandoz Ag	Process of preparation of olanzapine form i
SI21270A (sl)	2002-07-15	2004-02-29	Krka, Tovarna Zdravil, D.D., Novo Mesto	Kristalne oblike olanzapina in postopki za njihovo pripravo
WO2004058773A1 (en) *	2002-12-24	2004-07-15	Teva Pharmaceutical Industries Ltd.	Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
JP2007511605A (ja) *	2003-11-18	2007-05-10	スリーエムイノベイティブプロパティズカンパニー	オランザピン含有経皮薬物送達組成物
DE602004014264D1 (de) *	2003-12-22	2008-07-17	Teva Pharma	Verfahren zur herstellung von olanzapin
WO2005070938A1 (en)	2004-01-27	2005-08-04	Synthon B.V.	Stable salts of olanzapine
EP1716154A1 (en) *	2004-02-19	2006-11-02	Neuland Laboratories Ltd	Process for the preparation of olanzapine form 1 useful as antipsychotic drug
WO2006006185A1 (en) *	2004-07-14	2006-01-19	Shasun Chemicals And Drugs Limited	Improved process for making form i of olanzapine.
ES2253091B1 (es)	2004-07-27	2007-02-01	Inke, S.A.	Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
DE112005000641T5 (de)	2004-09-06	2007-09-06	Shasun Chemicals and Drugs Ltd., Chennai	Neues Verfahren zur Herstellung einer pharmazeutisch reinen polymorphen Form I von Olanzapin
CA2587710C (en) *	2004-11-16	2014-10-21	Elan Pharma International Ltd.	Injectable nanoparticulate olanzapine formulations
US7834176B2 (en)	2006-01-26	2010-11-16	Sandoz Ag	Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) *	2007-06-14	2008-12-14	Apotex Pharmachem Inc.	Novel processes to form-i of olanzapine
EP2486913A1 (en)	2011-02-14	2012-08-15	Labtec GmbH	Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) *	2012-12-20	2016-10-19	株式会社トクヤマ	オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5302716A (en) *	1986-01-16	1994-04-12	Schering Corporation	Fused benzazepines
CA2002596A1 (en) *	1988-11-14	1990-05-14	Thomas M. Eckrich	Hydrates of b-lactam antibiotic
GB9009229D0 (en) *	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
US5229382A (en) *	1990-04-25	1993-07-20	Lilly Industries Limited	2-methyl-thieno-benzodiazepine
AU668159B2 (en) *	1992-05-29	1996-04-26	Lilly Industries Limited	Pharmaceutical compounds
US5550231A (en) *	1993-06-15	1996-08-27	Eli Lilly And Company	Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) *	1994-12-12	1997-02-11	Allelix Biopharmaceuticals, Inc.	5-HT2 receptor ligands
US5637584A (en) *	1995-03-24	1997-06-10	Eli Lilly And Company	Solvate of olanzapine
US5631250A (en) *	1995-03-24	1997-05-20	Eli Lilly And Company	Process and solvate of 2-methyl-thieno-benzodiazepine
EG24221A (en) *	1995-03-24	2008-11-10	Lilly Co Eli	Process for preparing olanzapine
EG23659A (en) *	1995-03-24	2007-03-26	Lilly Co Eli	Process and crystal forms of methyl-thieno-benzodiazepine
RS49597B (sr) *	1996-09-23	2007-06-04	Eli Lilly And Company,	Olanzapin dihidrat d

1997
- 1997-09-02 ZA ZA978515A patent/ZA978515B/xx unknown
- 1997-09-18 CA CA002265712A patent/CA2265712C/en not_active Expired - Lifetime
- 1997-09-18 JP JP10514842A patent/JP2001500877A/ja not_active Withdrawn
- 1997-09-18 HU HU0000066A patent/HU226484B1/hu unknown
- 1997-09-18 CN CN97198137A patent/CN1122036C/zh not_active Expired - Lifetime
- 1997-09-18 PL PL381479A patent/PL196068B1/pl unknown
- 1997-09-18 AU AU44841/97A patent/AU719441B2/en not_active Expired
- 1997-09-18 PL PL97332482A patent/PL194565B1/pl unknown
- 1997-09-18 BR BR9712100-2A patent/BR9712100A/pt not_active Application Discontinuation
- 1997-09-18 KR KR1019997002424A patent/KR100560015B1/ko not_active IP Right Cessation
- 1997-09-18 IL IL12896297A patent/IL128962A/xx not_active IP Right Cessation
- 1997-09-18 EA EA199900326A patent/EA001642B1/ru not_active IP Right Cessation
- 1997-09-18 WO PCT/US1997/016499 patent/WO1998012199A1/en not_active Application Discontinuation
- 1997-09-18 CZ CZ0099099A patent/CZ299248B6/cs not_active IP Right Cessation
- 1997-09-18 ID IDW990058D patent/ID27275A/id unknown
- 1997-09-18 TR TR1999/00640T patent/TR199900640T2/xx unknown
- 1997-09-18 NZ NZ334448A patent/NZ334448A/en not_active IP Right Cessation
- 1997-09-18 UA UA99031635A patent/UA59371C2/uk unknown
- 1997-09-18 RS YUP-155/99A patent/RS49598B/sr unknown
- 1997-09-18 PL PL381478A patent/PL196069B1/pl unknown
- 1997-09-19 IN IN1736CA1997 patent/IN187156B/en unknown
- 1997-09-22 SV SV1997000081A patent/SV1997000081A/es not_active Application Discontinuation
- 1997-09-22 PT PT97307383T patent/PT831098E/pt unknown
- 1997-09-22 SI SI9730288T patent/SI0831098T1/xx unknown
- 1997-09-22 MY MYPI97004392A patent/MY125565A/en unknown
- 1997-09-22 ES ES97307383T patent/ES2166051T3/es not_active Expired - Lifetime
- 1997-09-22 DK DK97307383T patent/DK0831098T3/da active
- 1997-09-22 EP EP97307383A patent/EP0831098B1/en not_active Expired - Lifetime
- 1997-09-22 DE DE69708428T patent/DE69708428T2/de not_active Expired - Lifetime
- 1997-09-22 AT AT97307383T patent/ATE209208T1/de active
- 1997-09-22 CO CO97055061A patent/CO4910140A1/es unknown
- 1997-09-23 AR ARP970104362A patent/AR013838A1/es not_active Application Discontinuation
- 1997-09-23 US US08/935,884 patent/US6020487A/en not_active Expired - Lifetime
- 1997-09-23 EG EG98697A patent/EG23861A/xx active
- 1997-09-23 PE PE1997000855A patent/PE110398A1/es active IP Right Grant
1998
- 1998-02-27 TW TW086113832A patent/TW470746B/zh not_active IP Right Cessation
- 1998-09-21 HK HK98110796A patent/HK1009807A1/xx not_active IP Right Cessation
1999
- 1999-03-22 NO NO19991382A patent/NO323980B1/no not_active IP Right Cessation
2009
- 2009-06-05 JP JP2009135901A patent/JP2009242407A/ja active Pending

Also Published As

Publication number	Publication date
DE69708428T2 (de)	2002-07-04
SI0831098T1 (en)	2002-04-30
ATE209208T1 (de)	2001-12-15
NZ334448A (en)	2000-08-25
WO1998012199A1 (en)	1998-03-26
CZ299248B6 (cs)	2008-05-28
SV1997000081A (es)	1999-01-14
NO323980B1 (no)	2007-07-30
TR199900640T2 (xx)	1999-06-21
ID27275A (id)	2001-03-22
CN1122036C (zh)	2003-09-24
EP0831098B1 (en)	2001-11-21
KR100560015B1 (ko)	2006-03-15
PL194565B1 (pl)	2007-06-29
EP0831098A2 (en)	1998-03-25
YU15599A (sh)	2001-12-26
EA001642B1 (ru)	2001-06-25
IN187156B (uk)	2002-02-16
NO991382D0 (no)	1999-03-22
NO991382L (no)	1999-03-22
IL128962A0 (en)	2000-02-17
ES2166051T3 (es)	2002-04-01
CO4910140A1 (es)	2000-04-24
EP0831098A3 (en)	1998-04-29
CZ99099A3 (cs)	1999-11-17
HU226484B1 (en)	2009-03-02
PE110398A1 (es)	1999-01-14
AR013838A1 (es)	2001-01-31
PL332482A1 (en)	1999-09-13
EG23861A (en)	2007-11-18
UA59371C2 (uk)	2003-09-15
ZA978515B (en)	1999-03-23
DE69708428D1 (de)	2002-01-03
BR9712100A (pt)	1999-08-31
HUP0000066A2 (hu)	2000-06-28
RS49598B (sr)	2007-06-04
AU4484197A (en)	1998-04-14
CA2265712C (en)	2006-10-31
PL196068B1 (pl)	2007-12-31
CA2265712A1 (en)	1998-03-26
MY125565A (en)	2006-08-30
PT831098E (pt)	2002-04-29
HUP0000066A3 (en)	2000-11-28
AU719441B2 (en)	2000-05-11
PL196069B1 (pl)	2007-12-31
CN1234802A (zh)	1999-11-10
JP2009242407A (ja)	2009-10-22
EA199900326A1 (ru)	1999-08-26
JP2001500877A (ja)	2001-01-23
IL128962A (en)	2003-01-12
KR20000048520A (ko)	2000-07-25
HK1009807A1 (en)	1999-06-11
TW470746B (en)	2002-01-01
US6020487A (en)	2000-02-01

Publication	Publication Date	Title
DK0831098T3 (da)	2002-05-21	Mellemprodukter og fremgangsmåde til fremstilling af olanzapin
DK0770615T3 (da)	2003-07-14	Fremgangsmåde til fremstilling af dihalogenazolopyrimidiner
DK1038008T3 (da)	2007-03-12	Fremgangsmåde til fremstilling af EGIII-lignende enzymer
DK0811682T3 (da)	2004-05-17	Fremgangsmåde til fremstilling af L-lysin
DK0922040T3 (da)	2005-04-04	Fremgangsmåde til fremstilling af mellemprodukter til florfenicol
DK21995A (da)	1995-09-03	Forbinding og fremgangsmade til fremstilling af forbinding
DK0939749T3 (da)	2001-11-05	Fremgangsmåde til fremstilling af benzylethere
DK0991666T3 (da)	2008-04-14	Alfa-1-antitrypsin-præparat og fremgangsmåde til fremstilling heraf
NO20012963L (no)	2001-06-15	Fremgangsmåte for fremstilling av 3-alkanoylindoler og 3- alkylindoler
DK0756597T3 (da)	2001-08-20	Fremgangsmåde til fremstilling af puriner
DK0768310T3 (da)	2000-04-17	Fremgangsmåde til fremstilling af imidazo-benzodiazepin-derivater
DK0877738T3 (da)	2003-09-08	Fremgangsmåde til fremstilling af phenylimidazolidinderivater
DK0912603T3 (da)	2004-02-09	Fremgangsmåde til fremstilling af visse azacyclohexapeptider
DK0970077T3 (da)	2003-09-01	Forbedret fremgangsmåde til fremstilling af thiazolidindioner og nye thiazolidindioner
DK0946514T3 (da)	2003-08-25	Fremgangsmåde til fremstilling af n-substituerede 3-hydroxypyrazoler
DK1039888T3 (da)	2003-06-16	Fremgangsmåde til forøgelse af produktionen og forbedring af kvaliteten af sæd
DK0905128T3 (da)	2002-03-25	Fremgangsmåder og mellemprodukter egnede til fremstilling af antifolater
DK0864564T3 (da)	2002-09-23	Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater
DK0983249T3 (da)	2002-07-08	Fremgangsmåder og mellemprodukter til fremstilling af substituerede indazolderivater
DK0648738T3 (da)	1997-06-16	Fremgangsmåde til fremstilling af acetoacetarylamider
DK1036319T3 (da)	2006-01-16	Fremgangsmåde til opnåelse af L-dihydroorotsyre og anvendelse deraf
DK0648748T3 (da)	1997-10-13	Fremgangsmåde til fremstilling af 5-acetoacetylaminobenzimidazolon-2
DK1012152T3 (da)	2003-02-10	Fremgangsmåde til fremstilling af oxazaphosphorin-2-aminer
DK0721929T3 (da)	2000-03-27	Fremgangsmåde til fremstilling af hydroxyalkoxybenzophenoner
DK0855379T3 (da)	2001-12-17	Fremgangsmåde til fremstilling af benzophenonderivater