BR9712100A - Intermediários e processo para preparar olanzapina. - Google Patents

Intermediários e processo para preparar olanzapina.

Info

Publication number
BR9712100A
BR9712100A BR9712100-2A BR9712100A BR9712100A BR 9712100 A BR9712100 A BR 9712100A BR 9712100 A BR9712100 A BR 9712100A BR 9712100 A BR9712100 A BR 9712100A
Authority
BR
Brazil
Prior art keywords
intermediates
preparing
preparing olanzapine
olanzapine
olazapine
Prior art date
Application number
BR9712100-2A
Other languages
English (en)
Inventor
Charles A Bunnell
Samuel D Larsen
John R Nichols
Susan M Reutzel
Gregory A Stephenson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9712100(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of BR9712100A publication Critical patent/BR9712100A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Abstract

Patente de Invenção:<B>"INTERMEDIáRIOS E PROCESSO PARA PREPARAR OLANZAPINA"<D>. A presente invenção fornece um processo para preparar olazapina e seus intermediários.
BR9712100-2A 1996-09-23 1997-09-18 Intermediários e processo para preparar olanzapina. BR9712100A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2648796P 1996-09-23 1996-09-23
PCT/US1997/016499 WO1998012199A1 (en) 1996-09-23 1997-09-18 Intermediates and process for preparing olanzapine

Publications (1)

Publication Number Publication Date
BR9712100A true BR9712100A (pt) 1999-08-31

Family

ID=21832120

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9712100-2A BR9712100A (pt) 1996-09-23 1997-09-18 Intermediários e processo para preparar olanzapina.

Country Status (36)

Country Link
US (1) US6020487A (pt)
EP (1) EP0831098B1 (pt)
JP (2) JP2001500877A (pt)
KR (1) KR100560015B1 (pt)
CN (1) CN1122036C (pt)
AR (1) AR013838A1 (pt)
AT (1) ATE209208T1 (pt)
AU (1) AU719441B2 (pt)
BR (1) BR9712100A (pt)
CA (1) CA2265712C (pt)
CO (1) CO4910140A1 (pt)
CZ (1) CZ299248B6 (pt)
DE (1) DE69708428T2 (pt)
DK (1) DK0831098T3 (pt)
EA (1) EA001642B1 (pt)
EG (1) EG23861A (pt)
ES (1) ES2166051T3 (pt)
HK (1) HK1009807A1 (pt)
HU (1) HU226484B1 (pt)
ID (1) ID27275A (pt)
IL (1) IL128962A (pt)
IN (1) IN187156B (pt)
MY (1) MY125565A (pt)
NO (1) NO323980B1 (pt)
NZ (1) NZ334448A (pt)
PE (1) PE110398A1 (pt)
PL (3) PL196068B1 (pt)
PT (1) PT831098E (pt)
RS (1) RS49598B (pt)
SI (1) SI0831098T1 (pt)
SV (1) SV1997000081A (pt)
TR (1) TR199900640T2 (pt)
TW (1) TW470746B (pt)
UA (1) UA59371C2 (pt)
WO (1) WO1998012199A1 (pt)
ZA (1) ZA978515B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ2003566A3 (cs) * 2000-08-31 2004-01-14 Dr. Reddy's Laboratories Ltd. Způsob přípravy hydrátů olanzapinu a jejich konverze na krystalické formy olanzapinu
US6740753B2 (en) * 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
CA2464306A1 (en) * 2001-10-29 2003-05-08 Dr. Reddy's Laboratories Ltd. Olanzapine dihydrate-ii a process for its preparation and use thereof
CH695862A5 (fr) 2001-12-24 2006-09-29 Sun Pharmaceutical Ind Ltd Forme cristalline I de la methyl-4-(4-methyl-1-piperazinyl) 10H-thieno [2,3-b] [1,5] benzodiazepine.
WO2003091260A1 (en) * 2002-04-23 2003-11-06 Dr. Reddy's Laboratories Limited Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
SI1513846T1 (sl) 2002-05-31 2011-11-30 Sandoz Ag Postopek za pripravo olanzapina form I
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en) 2002-12-24 2008-01-29 Teva Pharmaceutical Industries Ltd. Crystal forms, methods for their preparation and method for preparation of olanzapine
CA2546200A1 (en) * 2003-11-18 2005-06-02 3M Innovative Properties Company Olanzapine containing transdermal drug delivery compositions
CA2551806A1 (en) * 2003-12-22 2005-07-14 Teva Pharmaceutical Industries, Ltd. Methods of preparing olanzapine
DE602005027308D1 (de) 2004-01-27 2011-05-19 Synthon Bv Stabile salze von olanzapin
WO2005080401A1 (en) * 2004-02-19 2005-09-01 Neuland Laboratories Limited Process for the preparation of olanzapine form 1 useful as antipsychotic drug
WO2006006185A1 (en) * 2004-07-14 2006-01-19 Shasun Chemicals And Drugs Limited Improved process for making form i of olanzapine.
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
WO2006027800A1 (en) * 2004-09-06 2006-03-16 Shasun Chemicals And Drugs Limited A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine
EP2623095A1 (en) * 2004-11-16 2013-08-07 Elan Pharma International Limited Injectable nanoparticulate olanzapine formulations
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) * 2007-06-14 2008-12-14 Apotex Pharmachem Inc. Novel processes to form-i of olanzapine
EP2486913A1 (en) 2011-02-14 2012-08-15 Labtec GmbH Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
ES2153373T3 (es) * 1992-05-29 2001-03-01 Lilly Co Eli Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central.
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
ID21924A (id) * 1996-09-23 1999-08-12 Lilly Co Eli Olanzapin dihidrat d

Also Published As

Publication number Publication date
ID27275A (id) 2001-03-22
IL128962A0 (en) 2000-02-17
YU15599A (sh) 2001-12-26
AU4484197A (en) 1998-04-14
JP2001500877A (ja) 2001-01-23
TW470746B (en) 2002-01-01
EA001642B1 (ru) 2001-06-25
ZA978515B (en) 1999-03-23
NO323980B1 (no) 2007-07-30
SI0831098T1 (en) 2002-04-30
NO991382D0 (no) 1999-03-22
DK0831098T3 (da) 2002-05-21
KR20000048520A (ko) 2000-07-25
EP0831098A2 (en) 1998-03-25
PL196068B1 (pl) 2007-12-31
CZ299248B6 (cs) 2008-05-28
ES2166051T3 (es) 2002-04-01
NZ334448A (en) 2000-08-25
WO1998012199A1 (en) 1998-03-26
CA2265712A1 (en) 1998-03-26
HUP0000066A2 (hu) 2000-06-28
CZ99099A3 (cs) 1999-11-17
PT831098E (pt) 2002-04-29
AR013838A1 (es) 2001-01-31
JP2009242407A (ja) 2009-10-22
PE110398A1 (es) 1999-01-14
DE69708428D1 (de) 2002-01-03
TR199900640T2 (xx) 1999-06-21
NO991382L (no) 1999-03-22
KR100560015B1 (ko) 2006-03-15
HK1009807A1 (en) 1999-06-11
DE69708428T2 (de) 2002-07-04
CN1234802A (zh) 1999-11-10
HU226484B1 (en) 2009-03-02
AU719441B2 (en) 2000-05-11
CN1122036C (zh) 2003-09-24
CO4910140A1 (es) 2000-04-24
SV1997000081A (es) 1999-01-14
CA2265712C (en) 2006-10-31
US6020487A (en) 2000-02-01
RS49598B (sr) 2007-06-04
HUP0000066A3 (en) 2000-11-28
IL128962A (en) 2003-01-12
EP0831098B1 (en) 2001-11-21
PL194565B1 (pl) 2007-06-29
IN187156B (pt) 2002-02-16
EP0831098A3 (en) 1998-04-29
PL196069B1 (pl) 2007-12-31
ATE209208T1 (de) 2001-12-15
PL332482A1 (en) 1999-09-13
EG23861A (en) 2007-11-18
EA199900326A1 (ru) 1999-08-26
UA59371C2 (uk) 2003-09-15
MY125565A (en) 2006-08-30

Similar Documents

Publication Publication Date Title
BR9712100A (pt) Intermediários e processo para preparar olanzapina.
PT916675E (pt) Processo para preparacao de sildenafil
BR9905852A (pt) Poliuretanos termoplásticos alifáticos, processo para sua preparação e seu emprego
BR9400616A (pt) Processo para a preparação de 1,1,1,4,4,4-hexafluorbuteno-2
BR9907230B1 (pt) processo para a preparaÇço de um macrâmero.
ITMI931295A0 (it) Processo per la preparazione di cumene
BR9916187B1 (pt) processo para a preparação de 3-alcanoìla e 3-alquilindóis.
BR9706465A (pt) Processo para a preparação contínua de metilmercaptano
BR9508320A (pt) Processo para a preparação de um composto e cultura biologicamente
BR9400604A (pt) Processo para a preparação de 1,1,1,3,3-pentafluorpropano
BR9605759A (pt) Processo contínuo para preparação de 4-mino-2,2,6,6-tetrametilpiperidina
BR9709096A (pt) Processo para a preparação de 4,6-di-hidróxi-pirimidina
BR9905342A (pt) Caixa de câmbio
BR9400338A (pt) Processo para preparação de 1,1,1,2-tetrafluoro-2-cloroetano e de pentafluoretano
BR9707173A (pt) Processo para a preparação de um composto e composto
PT801070E (pt) Processo para a preparacao de um composto de platina
BR9403539A (pt) Um processo para a preparação de 5 (4H)-tetrazolinonas 1-tetrazolinonas 1-substituídas
BR9712773A (pt) Processo para a sìntese de benzotiofenos
BR9706239A (pt) Processo para preparação de 3-(1-hidroxifenil-1-alcoxiimino-metil)dioxazinas
PT929299E (pt) 1,2,3,4-tetra-hidro-2-dibenzofuranaminas e 2-aminociclo-hepta ¬b| benzofuranos substituidos
ITRM930502A0 (it) Procedimento per la produzione di r amminocarnitina e s amminocarnitina.
BR9407024A (pt) Processo para a preparação de 4,6-diamino-5-cianopirimidinas substituídas
BR9810481A (pt) Processo para preparação de 1h-indol-3-glioxamidas 4-substituìdas.
PT1131299E (pt) Processo para o fabrico de 5-hidroxipirazois ou de 3-hidroxipirazois 1-substituidos
BR9100447A (pt) Processo para a floculacao de um caldo aquoso de enzima

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL.7: C07D 415/04, C07D 243/10, A61K 31/55

Ipc: C07D 495/04 (2007.01), C07D 243/10 (2007.01), A61K

B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]

Free format text: COM A PETICAO NO020070092567, DE 09/07/2007, A REQUERENTE APRESENTOU MANIFESTACAO SOBRE O PARECER PUBLICADO NA RPI 1892, DE 10/04/2007, COM NOVAS VIAS DO QUADRO REIVINDICATORIO (TOTAL DE 15 REIVINDICACOES). NO ENTANTO, NA PETICAO NO 035063, DE 14/09/2000, ONDE A REQUERENTE SOLICITOU O EXAME DO PRESENTE PEDIDO, E INDICADO O PAGAMENTO RELATIVO A 13 REIVINDICACOES. DESSE MODO, A FIM DE DAR CONTINUIDADE AO EXAME DO PEDIDO, A REQUERENTE DEVERA COMPLEMENTAR A RETRIBUICAO EQUIVALENTE A 02 (DUAS) REIVINDICACOES EXCEDENTES

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PRESENTE PEDIDO UMA VEZ QUE ESTE NAO ATENDE AOS ARTIGOS 8O E 13 DA LEI 9279/96 (LPI).

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.