DK0864564T3 - Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater - Google Patents

Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater

Info

Publication number
DK0864564T3
DK0864564T3 DK98103570T DK98103570T DK0864564T3 DK 0864564 T3 DK0864564 T3 DK 0864564T3 DK 98103570 T DK98103570 T DK 98103570T DK 98103570 T DK98103570 T DK 98103570T DK 0864564 T3 DK0864564 T3 DK 0864564T3
Authority
DK
Denmark
Prior art keywords
bromolactam
alpha
derivatives
preparation
particular method
Prior art date
Application number
DK98103570T
Other languages
English (en)
Inventor
Stefan Abrecht
Original Assignee
Basilea Pharmaceutica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basilea Pharmaceutica Ag filed Critical Basilea Pharmaceutica Ag
Application granted granted Critical
Publication of DK0864564T3 publication Critical patent/DK0864564T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D505/00Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK98103570T 1997-03-10 1998-03-02 Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater DK0864564T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97103964 1997-03-10

Publications (1)

Publication Number Publication Date
DK0864564T3 true DK0864564T3 (da) 2002-09-23

Family

ID=8226572

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98103570T DK0864564T3 (da) 1997-03-10 1998-03-02 Særlig fremgangsmåde til fremstillingen af alfa-bromlactamderivater

Country Status (16)

Country Link
US (1) US6114541A (da)
EP (1) EP0864564B1 (da)
JP (1) JP2938427B2 (da)
KR (1) KR100280561B1 (da)
CN (1) CN1193014A (da)
AR (1) AR015571A1 (da)
AT (1) ATE219056T1 (da)
AU (1) AU728147B2 (da)
BR (1) BR9800844A (da)
CA (1) CA2231631A1 (da)
CY (1) CY2392B1 (da)
DE (1) DE69805887T2 (da)
DK (1) DK0864564T3 (da)
ES (1) ES2176841T3 (da)
TR (1) TR199800403A2 (da)
ZA (1) ZA981885B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9901712D0 (sv) * 1999-05-11 1999-05-11 Astra Ab New process
US7741327B2 (en) 2008-04-16 2010-06-22 Hoffmann-La Roche Inc. Pyrrolidinone glucokinase activators
TWI685497B (zh) 2014-06-02 2020-02-21 西班牙商伊史帝夫製藥公司 具有多重模式抗疼痛活性的1-氧雜-4,9-二氮雜螺十一烷化合物之烷基衍生物
TW201615643A (zh) 2014-06-02 2016-05-01 伊史帝夫博士實驗室股份有限公司 具有多重模式抗疼痛活性之1-氧雜-4,9-二氮雜螺十一烷化合物之烷基與芳基衍生物
PL3365346T3 (pl) 2015-10-23 2020-06-01 Esteve Pharmaceuticals, S.A. Związki oksa-diazaspiro o działaniu przeciwbólowym
EP3365338B1 (en) 2015-10-23 2022-08-03 Esteve Pharmaceuticals, S.A. Substituted morpholine derivatives having activity against pain
US10183918B2 (en) 2015-10-23 2019-01-22 Laboratorios Del Dr. Esteve S.A. Oxa-azaspiro compounds having activity against pain
TWI756196B (zh) 2015-11-16 2022-03-01 西班牙商艾斯提夫製藥股份有限公司 用於治療藥物濫用和成癮之氧雜二氮雜螺環化合物
CN107129454A (zh) * 2017-05-04 2017-09-05 唐山威格化学工业有限公司 N‑辛基吡咯烷酮的合成方法
CA3076765A1 (en) 2017-10-17 2019-04-25 Esteve Pharmaceuticals, S.A. Salts of (r)-9-(2,5-difluorophenethyl)-4-ethyl-2-methyl-1-oxa-4,9-diazaspiro[5.5]undecan-3-one

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
PT620225E (pt) * 1993-04-16 2003-03-31 Basilea Pharmaceutica Ag Derivados de cefalosporina
US5811419A (en) * 1996-01-16 1998-09-22 Hoffmann-La Roche Inc. Isooxacephem-derivatives

Also Published As

Publication number Publication date
ATE219056T1 (de) 2002-06-15
CA2231631A1 (en) 1998-09-10
AU5737498A (en) 1998-09-10
CN1193014A (zh) 1998-09-16
CY2392B1 (en) 2004-09-10
KR100280561B1 (ko) 2001-02-01
TR199800403A3 (tr) 1998-09-21
BR9800844A (pt) 2000-05-02
US6114541A (en) 2000-09-05
AR015571A1 (es) 2001-05-16
JPH10273481A (ja) 1998-10-13
ZA981885B (en) 1998-09-10
ES2176841T3 (es) 2002-12-01
EP0864564B1 (en) 2002-06-12
DE69805887D1 (de) 2002-07-18
DE69805887T2 (de) 2003-02-20
EP0864564A1 (en) 1998-09-16
TR199800403A2 (xx) 1998-09-21
AU728147B2 (en) 2001-01-04
JP2938427B2 (ja) 1999-08-23
KR19980080035A (ko) 1998-11-25

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