ATE209208T1 - Zwischenprodukte und verfahren zur herstellung olanzapin - Google Patents

Zwischenprodukte und verfahren zur herstellung olanzapin

Info

Publication number: ATE209208T1
Authority: AT; Austria
Prior art keywords: olnzapine; producing; intermediate products; products; producing olnzapine
Prior art date: 1996-09-23

Application number

AT97307383T

Other languages

English (en)

Inventor

Charles Arthur Bunnell

Samuel Dean Larsen

John Richard Nichols

Susan Marie Reutzel

Gregory Alan Stephenson

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-23

Filing date

1997-09-22

Publication date

2001-12-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE209208(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1997-09-22 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

2001-12-15 Application granted granted Critical

2001-12-15 Publication of ATE209208T1 publication Critical patent/ATE209208T1/de

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

AT97307383T 1996-09-23 1997-09-22 Zwischenprodukte und verfahren zur herstellung olanzapin ATE209208T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2648796P	1996-09-23	1996-09-23

Publications (1)

Publication Number	Publication Date
ATE209208T1 true ATE209208T1 (de)	2001-12-15

Family

ID=21832120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT97307383T ATE209208T1 (de)	1996-09-23	1997-09-22	Zwischenprodukte und verfahren zur herstellung olanzapin

Country Status (36)

Country	Link
US (1)	US6020487A (de)
EP (1)	EP0831098B1 (de)
JP (2)	JP2001500877A (de)
KR (1)	KR100560015B1 (de)
CN (1)	CN1122036C (de)
AR (1)	AR013838A1 (de)
AT (1)	ATE209208T1 (de)
AU (1)	AU719441B2 (de)
BR (1)	BR9712100A (de)
CA (1)	CA2265712C (de)
CO (1)	CO4910140A1 (de)
CZ (1)	CZ299248B6 (de)
DE (1)	DE69708428T2 (de)
DK (1)	DK0831098T3 (de)
EA (1)	EA001642B1 (de)
EG (1)	EG23861A (de)
ES (1)	ES2166051T3 (de)
HK (1)	HK1009807A1 (de)
HU (1)	HU226484B1 (de)
ID (1)	ID27275A (de)
IL (1)	IL128962A (de)
IN (1)	IN187156B (de)
MY (1)	MY125565A (de)
NO (1)	NO323980B1 (de)
NZ (1)	NZ334448A (de)
PE (1)	PE110398A1 (de)
PL (3)	PL196068B1 (de)
PT (1)	PT831098E (de)
RS (1)	RS49598B (de)
SI (1)	SI0831098T1 (de)
SV (1)	SV1997000081A (de)
TR (1)	TR199900640T2 (de)
TW (1)	TW470746B (de)
UA (1)	UA59371C2 (de)
WO (1)	WO1998012199A1 (de)
ZA (1)	ZA978515B (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CZ2003566A3 (cs) *	2000-08-31	2004-01-14	Dr. Reddy's Laboratories Ltd.	Způsob přípravy hydrátů olanzapinu a jejich konverze na krystalické formy olanzapinu
US6740753B2 (en) *	2001-01-04	2004-05-25	Geneva Pharmaceuticals, Inc.	Olanzapine crystal modification
CA2464306A1 (en) *	2001-10-29	2003-05-08	Dr. Reddy's Laboratories Ltd.	Olanzapine dihydrate-ii a process for its preparation and use thereof
CH695862A5 (fr)	2001-12-24	2006-09-29	Sun Pharmaceutical Ind Ltd	Forme cristalline I de la methyl-4-(4-methyl-1-piperazinyl) 10H-thieno [2,3-b] [1,5] benzodiazepine.
WO2003091260A1 (en) *	2002-04-23	2003-11-06	Dr. Reddy's Laboratories Limited	Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
SI1513846T1 (sl)	2002-05-31	2011-11-30	Sandoz Ag	Postopek za pripravo olanzapina form I
SI21270A (sl)	2002-07-15	2004-02-29	Krka, Tovarna Zdravil, D.D., Novo Mesto	Kristalne oblike olanzapina in postopki za njihovo pripravo
US7323459B2 (en)	2002-12-24	2008-01-29	Teva Pharmaceutical Industries Ltd.	Crystal forms, methods for their preparation and method for preparation of olanzapine
CA2546200A1 (en) *	2003-11-18	2005-06-02	3M Innovative Properties Company	Olanzapine containing transdermal drug delivery compositions
CA2551806A1 (en) *	2003-12-22	2005-07-14	Teva Pharmaceutical Industries, Ltd.	Methods of preparing olanzapine
DE602005027308D1 (de)	2004-01-27	2011-05-19	Synthon Bv	Stabile salze von olanzapin
WO2005080401A1 (en) *	2004-02-19	2005-09-01	Neuland Laboratories Limited	Process for the preparation of olanzapine form 1 useful as antipsychotic drug
WO2006006185A1 (en) *	2004-07-14	2006-01-19	Shasun Chemicals And Drugs Limited	Improved process for making form i of olanzapine.
ES2253091B1 (es)	2004-07-27	2007-02-01	Inke, S.A.	Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
WO2006027800A1 (en) *	2004-09-06	2006-03-16	Shasun Chemicals And Drugs Limited	A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine
EP2623095A1 (de) *	2004-11-16	2013-08-07	Elan Pharma International Limited	Injizierbare Olanzapin-Formulierungen in Nanoteilchenform
US7834176B2 (en)	2006-01-26	2010-11-16	Sandoz Ag	Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) *	2007-06-14	2008-12-14	Apotex Pharmachem Inc.	Novel processes to form-i of olanzapine
EP2486913A1 (de)	2011-02-14	2012-08-15	Labtec GmbH	Orale Filmformulierungen für Olanzapin mit schneller Zersetzung
JP6008734B2 (ja) *	2012-12-20	2016-10-19	株式会社トクヤマ	オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5302716A (en) *	1986-01-16	1994-04-12	Schering Corporation	Fused benzazepines
CA2002596A1 (en) *	1988-11-14	1990-05-14	Thomas M. Eckrich	Hydrates of b-lactam antibiotic
US5229382A (en) *	1990-04-25	1993-07-20	Lilly Industries Limited	2-methyl-thieno-benzodiazepine
GB9009229D0 (en) *	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
ES2153373T3 (es) *	1992-05-29	2001-03-01	Lilly Co Eli	Derivados de tienobenzodiazepina para el tratamiento de trastornos del sistema nervioso central.
US5550231A (en) *	1993-06-15	1996-08-27	Eli Lilly And Company	Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) *	1994-12-12	1997-02-11	Allelix Biopharmaceuticals, Inc.	5-HT2 receptor ligands
US5637584A (en) *	1995-03-24	1997-06-10	Eli Lilly And Company	Solvate of olanzapine
US5631250A (en) *	1995-03-24	1997-05-20	Eli Lilly And Company	Process and solvate of 2-methyl-thieno-benzodiazepine
EG24221A (en) *	1995-03-24	2008-11-10	Lilly Co Eli	Process for preparing olanzapine
EG23659A (en) *	1995-03-24	2007-03-26	Lilly Co Eli	Process and crystal forms of methyl-thieno-benzodiazepine
ID21924A (id) *	1996-09-23	1999-08-12	Lilly Co Eli	Olanzapin dihidrat d

1997
- 1997-09-02 ZA ZA978515A patent/ZA978515B/xx unknown
- 1997-09-18 EA EA199900326A patent/EA001642B1/ru not_active IP Right Cessation
- 1997-09-18 CN CN97198137A patent/CN1122036C/zh not_active Expired - Lifetime
- 1997-09-18 PL PL381479A patent/PL196068B1/pl unknown
- 1997-09-18 CZ CZ0099099A patent/CZ299248B6/cs not_active IP Right Cessation
- 1997-09-18 UA UA99031635A patent/UA59371C2/uk unknown
- 1997-09-18 HU HU0000066A patent/HU226484B1/hu unknown
- 1997-09-18 IL IL12896297A patent/IL128962A/xx not_active IP Right Cessation
- 1997-09-18 PL PL381478A patent/PL196069B1/pl unknown
- 1997-09-18 PL PL97332482A patent/PL194565B1/pl unknown
- 1997-09-18 ID IDW990058D patent/ID27275A/id unknown
- 1997-09-18 RS YUP-155/99A patent/RS49598B/sr unknown
- 1997-09-18 NZ NZ334448A patent/NZ334448A/en not_active IP Right Cessation
- 1997-09-18 AU AU44841/97A patent/AU719441B2/en not_active Expired
- 1997-09-18 WO PCT/US1997/016499 patent/WO1998012199A1/en not_active Application Discontinuation
- 1997-09-18 KR KR1019997002424A patent/KR100560015B1/ko not_active IP Right Cessation
- 1997-09-18 BR BR9712100-2A patent/BR9712100A/pt not_active Application Discontinuation
- 1997-09-18 TR TR1999/00640T patent/TR199900640T2/xx unknown
- 1997-09-18 CA CA002265712A patent/CA2265712C/en not_active Expired - Lifetime
- 1997-09-18 JP JP10514842A patent/JP2001500877A/ja not_active Withdrawn
- 1997-09-19 IN IN1736CA1997 patent/IN187156B/en unknown
- 1997-09-22 ES ES97307383T patent/ES2166051T3/es not_active Expired - Lifetime
- 1997-09-22 AT AT97307383T patent/ATE209208T1/de active
- 1997-09-22 SI SI9730288T patent/SI0831098T1/xx unknown
- 1997-09-22 MY MYPI97004392A patent/MY125565A/en unknown
- 1997-09-22 CO CO97055061A patent/CO4910140A1/es unknown
- 1997-09-22 EP EP97307383A patent/EP0831098B1/de not_active Expired - Lifetime
- 1997-09-22 DE DE69708428T patent/DE69708428T2/de not_active Expired - Lifetime
- 1997-09-22 DK DK97307383T patent/DK0831098T3/da active
- 1997-09-22 SV SV1997000081A patent/SV1997000081A/es not_active Application Discontinuation
- 1997-09-22 PT PT97307383T patent/PT831098E/pt unknown
- 1997-09-23 PE PE1997000855A patent/PE110398A1/es active IP Right Grant
- 1997-09-23 AR ARP970104362A patent/AR013838A1/es not_active Application Discontinuation
- 1997-09-23 US US08/935,884 patent/US6020487A/en not_active Expired - Lifetime
- 1997-09-23 EG EG98697A patent/EG23861A/xx active
1998
- 1998-02-27 TW TW086113832A patent/TW470746B/zh not_active IP Right Cessation
- 1998-09-21 HK HK98110796A patent/HK1009807A1/xx not_active IP Right Cessation
1999
- 1999-03-22 NO NO19991382A patent/NO323980B1/no not_active IP Right Cessation
2009
- 2009-06-05 JP JP2009135901A patent/JP2009242407A/ja active Pending

Also Published As

Publication number	Publication date
ID27275A (id)	2001-03-22
IL128962A0 (en)	2000-02-17
YU15599A (sh)	2001-12-26
AU4484197A (en)	1998-04-14
JP2001500877A (ja)	2001-01-23
TW470746B (en)	2002-01-01
EA001642B1 (ru)	2001-06-25
ZA978515B (en)	1999-03-23
NO323980B1 (no)	2007-07-30
SI0831098T1 (en)	2002-04-30
NO991382D0 (no)	1999-03-22
DK0831098T3 (da)	2002-05-21
KR20000048520A (ko)	2000-07-25
EP0831098A2 (de)	1998-03-25
PL196068B1 (pl)	2007-12-31
CZ299248B6 (cs)	2008-05-28
ES2166051T3 (es)	2002-04-01
NZ334448A (en)	2000-08-25
WO1998012199A1 (en)	1998-03-26
CA2265712A1 (en)	1998-03-26
HUP0000066A2 (hu)	2000-06-28
CZ99099A3 (cs)	1999-11-17
PT831098E (pt)	2002-04-29
AR013838A1 (es)	2001-01-31
JP2009242407A (ja)	2009-10-22
PE110398A1 (es)	1999-01-14
DE69708428D1 (de)	2002-01-03
TR199900640T2 (xx)	1999-06-21
NO991382L (no)	1999-03-22
KR100560015B1 (ko)	2006-03-15
HK1009807A1 (en)	1999-06-11
DE69708428T2 (de)	2002-07-04
CN1234802A (zh)	1999-11-10
HU226484B1 (en)	2009-03-02
BR9712100A (pt)	1999-08-31
AU719441B2 (en)	2000-05-11
CN1122036C (zh)	2003-09-24
CO4910140A1 (es)	2000-04-24
SV1997000081A (es)	1999-01-14
CA2265712C (en)	2006-10-31
US6020487A (en)	2000-02-01
RS49598B (sr)	2007-06-04
HUP0000066A3 (en)	2000-11-28
IL128962A (en)	2003-01-12
EP0831098B1 (de)	2001-11-21
PL194565B1 (pl)	2007-06-29
IN187156B (de)	2002-02-16
EP0831098A3 (de)	1998-04-29
PL196069B1 (pl)	2007-12-31
PL332482A1 (en)	1999-09-13
EG23861A (en)	2007-11-18
EA199900326A1 (ru)	1999-08-26
UA59371C2 (uk)	2003-09-15
MY125565A (en)	2006-08-30

Legal Events

Date	Code	Title	Description
2002-03-15	UEP	Publication of translation of european patent specification

Publication	Publication Date	Title
DE69716779T2 (de)	2003-07-17	Produkte und verfahren zur herstellung von dilatatoren
DE69527054T2 (de)	2003-02-06	Retroreflektierender gegenstand und verfahren zur herstellung
DE69429873D1 (de)	2002-03-21	Teilchenförmige aromazusammenstellungen und verfahren zur herstellung derselben
DE69626833T2 (de)	2003-12-24	Ernährungsergänzungsgetränk und verfahren zur herstellung desselben
ATE258180T1 (de)	2004-02-15	Verfahren zur herstellung von glufosinate und zwischenprodukte dafür
ATE283847T1 (de)	2004-12-15	Verfahren zur herstellung von zwischenprodukten des florfenicols
DE69530954T2 (de)	2003-11-27	Mikromechanisches Bauelement und Verfahren zur Herstellung desselben
DE69829181D1 (de)	2005-04-07	Verbesserte trennsäulen und verfahren zur herstellung der verbesserten trennsäulen
DE69706429D1 (de)	2001-10-04	Verbesserte metalbehalter und verfahren zur herstellung
ATE209208T1 (de)	2001-12-15	Zwischenprodukte und verfahren zur herstellung olanzapin
DE69813312D1 (de)	2003-05-15	Verfahren zur herstellung von cyclopropylethyn sowie zwischenprodukte zur herstellung von cyclopropylethyn
DE69624792T2 (de)	2004-10-07	Verfahren und Vorrichtung zur Herstellung von lufthaltigen gefrorenen Produkten
DE69511248T2 (de)	1999-12-02	Polycarbomate, verfahren zur herstellung von polycarbomaten und verfahren zur herstellung von polyisocyanaten
ATE219767T1 (de)	2002-07-15	Verfahren zur herstellung von 2,4-dihydroxy- pyridin und 2,4-dihydroxy-3-nitropyridin
ATE249452T1 (de)	2003-09-15	Verfahren und zwischenprodukte zur herstellung substituierter chromanolderivate
DE69706976D1 (de)	2001-10-31	Kontinuierliches verfahren zur herstellung von hydrocarbylaluminoxanen
DE69522561T2 (de)	2002-07-11	Verfahren zur herstellung von benzophentionen und benzophenonen
ATE214373T1 (de)	2002-03-15	Verfahren und zwischenprodukte zur herstellung substituierter indazolderivate
ATE284390T1 (de)	2004-12-15	Verfahren und zwischenprodukte zur herstellung von 2,3-pyridindicarboxylatderivaten
DE69626299D1 (de)	2003-03-27	Halbleiteranordnung und verfahren zur herstellung
DE69726024D1 (de)	2003-12-11	Verfahren und vorrichtung zur herstellung von getränken
ATE203506T1 (de)	2001-08-15	Verfahren und zwischenprodukte zur herstellung von pestiziden-fluorolefinverbindungen
DE69419516D1 (de)	1999-08-19	Verfahren zur herstellung von hexafluorocyclobuten und verfahren zur herstellung von hexafluorocyclobutan
DE69617643T2 (de)	2002-08-08	Verfahren zur herstellung von difluormethan und difluorchlormethan
DE59700696D1 (de)	1999-12-16	Verfahren und zwischenprodukte zur herstellung von pyridyl-4-fluoranilinen