HK1009807A1 - Intermediates and process for preparing olanzapine - Google Patents

Intermediates and process for preparing olanzapine

Info

Publication number: HK1009807A1
Authority: HK; Hong Kong
Prior art keywords: intermediates; preparing olanzapine; olanzapine; preparing
Prior art date: 1996-09-23

Application number

HK98110796A

Other languages

English (en)

Inventor

Charles Arthur Bunnell

Samuel Dean Larsen

John Richard Nichols

Susan Marie Reutzel

Gregory Alan Stephenson

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-09-23

Filing date

1998-09-21

Publication date

1999-06-11

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1009807(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1998-09-21 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1999-06-11 Publication of HK1009807A1 publication Critical patent/HK1009807A1/xx

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

HK98110796A 1996-09-23 1998-09-21 Intermediates and process for preparing olanzapine HK1009807A1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US2648796P	1996-09-23	1996-09-23

Publications (1)

Publication Number	Publication Date
HK1009807A1 true HK1009807A1 (en)	1999-06-11

Family

ID=21832120

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
HK98110796A HK1009807A1 (en)	1996-09-23	1998-09-21	Intermediates and process for preparing olanzapine

Country Status (36)

Country	Link
US (1)	US6020487A (xx)
EP (1)	EP0831098B1 (xx)
JP (2)	JP2001500877A (xx)
KR (1)	KR100560015B1 (xx)
CN (1)	CN1122036C (xx)
AR (1)	AR013838A1 (xx)
AT (1)	ATE209208T1 (xx)
AU (1)	AU719441B2 (xx)
BR (1)	BR9712100A (xx)
CA (1)	CA2265712C (xx)
CO (1)	CO4910140A1 (xx)
CZ (1)	CZ299248B6 (xx)
DE (1)	DE69708428T2 (xx)
DK (1)	DK0831098T3 (xx)
EA (1)	EA001642B1 (xx)
EG (1)	EG23861A (xx)
ES (1)	ES2166051T3 (xx)
HK (1)	HK1009807A1 (xx)
HU (1)	HU226484B1 (xx)
ID (1)	ID27275A (xx)
IL (1)	IL128962A (xx)
IN (1)	IN187156B (xx)
MY (1)	MY125565A (xx)
NO (1)	NO323980B1 (xx)
NZ (1)	NZ334448A (xx)
PE (1)	PE110398A1 (xx)
PL (3)	PL196069B1 (xx)
PT (1)	PT831098E (xx)
RS (1)	RS49598B (xx)
SI (1)	SI0831098T1 (xx)
SV (1)	SV1997000081A (xx)
TR (1)	TR199900640T2 (xx)
TW (1)	TW470746B (xx)
UA (1)	UA59371C2 (xx)
WO (1)	WO1998012199A1 (xx)
ZA (1)	ZA978515B (xx)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SK2502003A3 (en) *	2000-08-31	2004-03-02	Reddys Lab Ltd Dr	Process for preparation of hydrates of olanzapine and their conversion into crystalline forms of olanzapine
US6740753B2 (en)	2001-01-04	2004-05-25	Geneva Pharmaceuticals, Inc.	Olanzapine crystal modification
WO2003037903A1 (en) *	2001-10-29	2003-05-08	Dr. Reddy's Laboratories Ltd.	Olanzapine dihydrate-ii a process for its preparation and use thereof
AU2002367119A1 (en)	2001-12-24	2003-07-15	Sun Pharmaceutical Industries Limited	Crystalline form I of 2-methyl-4-(4-methyl-1-piperazinyl) 10H thieno [2,3-b][1,5]benzodiazepine
WO2003091260A1 (en) *	2002-04-23	2003-11-06	Dr. Reddy's Laboratories Limited	Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
WO2003101997A1 (en) *	2002-05-31	2003-12-11	Geneva Pharmaceuticals, Inc.	Process of preparation of olanzapine form i
SI21270A (sl)	2002-07-15	2004-02-29	Krka, Tovarna Zdravil, D.D., Novo Mesto	Kristalne oblike olanzapina in postopki za njihovo pripravo
AU2003300324A1 (en)	2002-12-24	2004-07-22	Teva Pharmaceutical Industries Ltd.	Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
EP1684734A2 (en) *	2003-11-18	2006-08-02	3M Innovative Properties Company	Olanzapine containing transdermal drug delivery compositions
ES2308304T3 (es) *	2003-12-22	2008-12-01	Teva Pharmaceutical Industries Ltd.	Procedimientos de preparacion de la olanzapina.
ATE504588T1 (de)	2004-01-27	2011-04-15	Synthon Bv	Stabile salze von olanzapin
WO2005080401A1 (en) *	2004-02-19	2005-09-01	Neuland Laboratories Limited	Process for the preparation of olanzapine form 1 useful as antipsychotic drug
EP1781666A1 (en) *	2004-07-14	2007-05-09	Shasun Chemicals and Drugs Limited	Improved process for making form i of olanzapine.
ES2253091B1 (es)	2004-07-27	2007-02-01	Inke, S.A.	Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
WO2006027800A1 (en) *	2004-09-06	2006-03-16	Shasun Chemicals And Drugs Limited	A novel process for preparation of a pharmaceutically pure polymorphic form 1 of olanzapine
EA200701065A1 (ru) *	2004-11-16	2007-12-28	Элан Фарма Интернэшнл Лтд.	Инъецируемые составы, содержащие нанодисперсный оланзапин
US7834176B2 (en)	2006-01-26	2010-11-16	Sandoz Ag	Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) *	2007-06-14	2008-12-14	Apotex Pharmachem Inc.	Novel processes to form-i of olanzapine
EP2486913A1 (en)	2011-02-14	2012-08-15	Labtec GmbH	Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) *	2012-12-20	2016-10-19	株式会社トクヤマ	オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5302716A (en) *	1986-01-16	1994-04-12	Schering Corporation	Fused benzazepines
CA2002596A1 (en) *	1988-11-14	1990-05-14	Thomas M. Eckrich	Hydrates of b-lactam antibiotic
GB9009229D0 (en) *	1990-04-25	1990-06-20	Lilly Industries Ltd	Pharmaceutical compounds
US5229382A (en) *	1990-04-25	1993-07-20	Lilly Industries Limited	2-methyl-thieno-benzodiazepine
AU668159B2 (en) *	1992-05-29	1996-04-26	Lilly Industries Limited	Pharmaceutical compounds
US5550231A (en) *	1993-06-15	1996-08-27	Eli Lilly And Company	Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) *	1994-12-12	1997-02-11	Allelix Biopharmaceuticals, Inc.	5-HT2 receptor ligands
US5637584A (en) *	1995-03-24	1997-06-10	Eli Lilly And Company	Solvate of olanzapine
EG24221A (en) *	1995-03-24	2008-11-10	Lilly Co Eli	Process for preparing olanzapine
EG23659A (en) *	1995-03-24	2007-03-26	Lilly Co Eli	Process and crystal forms of methyl-thieno-benzodiazepine
US5631250A (en) *	1995-03-24	1997-05-20	Eli Lilly And Company	Process and solvate of 2-methyl-thieno-benzodiazepine
EA001881B1 (ru) *	1996-09-23	2001-10-22	Эли Лилли Энд Компани	Форма d дигидрата оланзапина

1997
- 1997-09-02 ZA ZA978515A patent/ZA978515B/xx unknown
- 1997-09-18 CN CN97198137A patent/CN1122036C/zh not_active Expired - Lifetime
- 1997-09-18 PL PL381478A patent/PL196069B1/pl unknown
- 1997-09-18 CZ CZ0099099A patent/CZ299248B6/cs not_active IP Right Cessation
- 1997-09-18 BR BR9712100-2A patent/BR9712100A/pt not_active Application Discontinuation
- 1997-09-18 NZ NZ334448A patent/NZ334448A/en not_active IP Right Cessation
- 1997-09-18 HU HU0000066A patent/HU226484B1/hu unknown
- 1997-09-18 JP JP10514842A patent/JP2001500877A/ja not_active Withdrawn
- 1997-09-18 IL IL12896297A patent/IL128962A/xx not_active IP Right Cessation
- 1997-09-18 RS YUP-155/99A patent/RS49598B/sr unknown
- 1997-09-18 EA EA199900326A patent/EA001642B1/ru not_active IP Right Cessation
- 1997-09-18 TR TR1999/00640T patent/TR199900640T2/xx unknown
- 1997-09-18 AU AU44841/97A patent/AU719441B2/en not_active Expired
- 1997-09-18 UA UA99031635A patent/UA59371C2/uk unknown
- 1997-09-18 PL PL97332482A patent/PL194565B1/pl unknown
- 1997-09-18 ID IDW990058D patent/ID27275A/id unknown
- 1997-09-18 WO PCT/US1997/016499 patent/WO1998012199A1/en not_active Application Discontinuation
- 1997-09-18 CA CA002265712A patent/CA2265712C/en not_active Expired - Lifetime
- 1997-09-18 KR KR1019997002424A patent/KR100560015B1/ko not_active IP Right Cessation
- 1997-09-18 PL PL381479A patent/PL196068B1/pl unknown
- 1997-09-19 IN IN1736CA1997 patent/IN187156B/en unknown
- 1997-09-22 PT PT97307383T patent/PT831098E/pt unknown
- 1997-09-22 ES ES97307383T patent/ES2166051T3/es not_active Expired - Lifetime
- 1997-09-22 EP EP97307383A patent/EP0831098B1/en not_active Expired - Lifetime
- 1997-09-22 SI SI9730288T patent/SI0831098T1/xx unknown
- 1997-09-22 MY MYPI97004392A patent/MY125565A/en unknown
- 1997-09-22 DK DK97307383T patent/DK0831098T3/da active
- 1997-09-22 CO CO97055061A patent/CO4910140A1/es unknown
- 1997-09-22 AT AT97307383T patent/ATE209208T1/de active
- 1997-09-22 SV SV1997000081A patent/SV1997000081A/es not_active Application Discontinuation
- 1997-09-22 DE DE69708428T patent/DE69708428T2/de not_active Expired - Lifetime
- 1997-09-23 PE PE1997000855A patent/PE110398A1/es active IP Right Grant
- 1997-09-23 AR ARP970104362A patent/AR013838A1/es not_active Application Discontinuation
- 1997-09-23 EG EG98697A patent/EG23861A/xx active
- 1997-09-23 US US08/935,884 patent/US6020487A/en not_active Expired - Lifetime
1998
- 1998-02-27 TW TW086113832A patent/TW470746B/zh not_active IP Right Cessation
- 1998-09-21 HK HK98110796A patent/HK1009807A1/xx not_active IP Right Cessation
1999
- 1999-03-22 NO NO19991382A patent/NO323980B1/no not_active IP Right Cessation
2009
- 2009-06-05 JP JP2009135901A patent/JP2009242407A/ja active Pending

Also Published As

Publication number	Publication date
HU226484B1 (en)	2009-03-02
BR9712100A (pt)	1999-08-31
PL196068B1 (pl)	2007-12-31
PL196069B1 (pl)	2007-12-31
MY125565A (en)	2006-08-30
NZ334448A (en)	2000-08-25
WO1998012199A1 (en)	1998-03-26
UA59371C2 (uk)	2003-09-15
DK0831098T3 (da)	2002-05-21
CN1234802A (zh)	1999-11-10
EA001642B1 (ru)	2001-06-25
NO991382D0 (no)	1999-03-22
DE69708428D1 (de)	2002-01-03
KR20000048520A (ko)	2000-07-25
JP2001500877A (ja)	2001-01-23
JP2009242407A (ja)	2009-10-22
KR100560015B1 (ko)	2006-03-15
EP0831098A2 (en)	1998-03-25
EA199900326A1 (ru)	1999-08-26
SI0831098T1 (en)	2002-04-30
AU4484197A (en)	1998-04-14
ID27275A (id)	2001-03-22
CA2265712C (en)	2006-10-31
HUP0000066A2 (hu)	2000-06-28
EG23861A (en)	2007-11-18
TW470746B (en)	2002-01-01
EP0831098A3 (en)	1998-04-29
CZ299248B6 (cs)	2008-05-28
CA2265712A1 (en)	1998-03-26
PL194565B1 (pl)	2007-06-29
NO991382L (no)	1999-03-22
IN187156B (xx)	2002-02-16
PL332482A1 (en)	1999-09-13
SV1997000081A (es)	1999-01-14
ZA978515B (en)	1999-03-23
ES2166051T3 (es)	2002-04-01
ATE209208T1 (de)	2001-12-15
RS49598B (sr)	2007-06-04
AR013838A1 (es)	2001-01-31
PT831098E (pt)	2002-04-29
TR199900640T2 (xx)	1999-06-21
CN1122036C (zh)	2003-09-24
US6020487A (en)	2000-02-01
PE110398A1 (es)	1999-01-14
HUP0000066A3 (en)	2000-11-28
IL128962A (en)	2003-01-12
YU15599A (sh)	2001-12-26
AU719441B2 (en)	2000-05-11
CO4910140A1 (es)	2000-04-24
DE69708428T2 (de)	2002-07-04
IL128962A0 (en)	2000-02-17
CZ99099A3 (cs)	1999-11-17
NO323980B1 (no)	2007-07-30
EP0831098B1 (en)	2001-11-21

Legal Events

Date	Code	Title	Description
2004-12-15	PF	Patent in force
2006-04-28	PC	Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)	Effective date: 20050922

Publication	Publication Date	Title
AP9901444A0 (en)	1999-03-31	Erythrommycins and process for their preparation
HUP9800208A3 (en)	2000-04-28	Omega-cycloalkyl-prostaglandin e2-derivatives and process for preparing them
GB9609441D0 (en)	1996-07-10	Process
EG23861A (en)	2007-11-18	Intermediates and process for preparing olanzapine
HU9702508D0 (en)	1998-03-02	Vitronectin-receptor-antagonists and process for producing them
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PL321699A1 (en)	1998-03-30	Tempering process
GB9602046D0 (en)	1996-04-03	Process
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HUP9904112A3 (en)	2001-07-30	Process for preparing amidines
GB2316403B (en)	2000-04-26	Process
GB9610666D0 (en)	1996-07-31	Milk-shakes and process for making them
HUP9801594A3 (en)	2000-03-28	Novel seco-azalides and process for preparing them
IL141354A0 (en)	2002-03-10	Hydroxyphenyl-hydroximinomethyl-dioxazines and process for preparing them
GB9610470D0 (en)	1996-07-24	Article making method
HUP9903692A3 (en)	2000-07-28	Process for making dihydropyrimidinones